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Cervical cytology quality

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https://www.readbyqxmd.com/read/29770623/quality-of-tissue-from-punch-biopsy-forceps-vs-round-loop-electrode-in-colposcopically-directed-biopsy-a-randomized-controlled-trial
#1
Thanita Wetcho, Athithan Rattanaburi, Kanet Kanjanapradit
OBJECTIVE: To compare the quality of tissue from punch biopsy forceps (PB group) with round loop electrode (LE group) in colposcopically directed biopsy along with the evaluation of pain associated with each procedure. METHODS: Patients with abnormal cervical cytologic results and abnormal colposcopic findings were enrolled into a randomized trial into either a PB group or LE group. The quality of tissue was evaluated in regards to the size of tissue, site of tissue, and tissue damage...
March 12, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29767914/impact-of-applying-a-learning-strategy-to-improve-the-sample-quality-in-cervical-screening-in-nursing-staff-in-social-service
#2
Sandra Olimpia Gutiérrez Enríquez, Luis Fernando Méndez Donjuan, Yolanda Terán Figueroa, Darío Gaytán Hernández, Cuauhtémoc Oros Ovalle, Aracely Díaz Oviedo
OBJECTIVES: The study sought to assess the impact of applying a learning strategy to improve the quality of sample collection during cervical screening by students from the Nursing Degree Program doing social service. METHODS: This was a longitudinal, quasi-experimental study with the participation of 23 interns from the Nursing Degree Program at a public university from San Luis Potosí, Mexico. The work assessed knowledge of practical skills in taking cervical cytology tests and the quality of samples before and after applying a learning strategy that included 10 h of theoretical training and 22 h of practices on themes related to sample collection in cervical screening...
October 2017: Investigación y Educación en Enfermería
https://www.readbyqxmd.com/read/29764329/preliminary-results-of-the-first-cervical-cancer-screening-programme-in-the-north-eastern-region-of-romania
#3
Ioana Păvăleanu, Dumitru Gafiţanu, Nicolae Ioanid, Mihaela Grigore
Objective Cervical cancer represents a major health problem in Romania. A national population-based cervical cancer screening programme was launched in 2012. The aims of the study were to assess the participation rate and to estimate the prevalence of epithelial cell abnormalities in the first four years of the programme in North Eastern Romania. Methods The participation rate, representing the proportion of eligible women screened in the programme, was evaluated for 2012-2016. The prevalence of cytological abnormalities was estimated by age group and calendar year...
January 1, 2018: Journal of Medical Screening
https://www.readbyqxmd.com/read/29729092/improved-removal-of-blood-contamination-from-thinprep-cervical-cytology-samples-for-raman-spectroscopic-analysis
#4
Damien Traynor, Shiyamala Duraipandian, Cara M Martin, John J O'Leary, Fiona M Lyng
There is an unmet need for methods to help in the early detection of cervical precancer. Optical spectroscopy-based techniques, such as Raman spectroscopy, have shown great potential for diagnosis of different cancers, including cervical cancer. However, relatively few studies have been carried out on liquid-based cytology (LBC) pap test specimens and confounding factors, such as blood contamination, have been identified. Previous work reported a method to remove blood contamination before Raman spectroscopy by pretreatment of the slides with hydrogen peroxide...
May 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/29684144/moving-towards-an-organized-cervical-cancer-screening-costs-and-impact
#5
Mireia Diaz, David Moriña, Vanesa Rodríguez-Salés, Raquel Ibáñez, Josep Alfons Espinás, Silvia de Sanjosé
Background: HPV screening has been shown to be more cost-effective than cytology screening under most scenarios. Furthermore, it should be offered only in organized programmes with good quality assurance mechanisms. This study analyses the comparative cost of the current policy of opportunistic cytology screening vs. a hypothetical organized programme based on primary HPV screening. Methods: Total cervical cancer expenditure was defined as the sum of three cost elements: (i) direct (medical and non-medical) costs, obtained from a calibrated Markov model of the natural history of HPV and cervical cancer; (ii) programmatic costs, estimated based on other organized screening programmes; and (iii) indirect costs, extrapolated from previously published data...
April 18, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29659930/automated-cervical-screening-and-triage-based-on-hpv-testing-and-computer-interpreted-cytology
#6
Kai Yu, Noorie Hyun, Barbara Fetterman, Thomas Lorey, Tina R Raine-Bennett, Han Zhang, Robin E Stamps, Nancy E Poitras, William Wheeler, Brian Befano, Julia C Gage, Philip E Castle, Nicolas Wentzensen, Mark Schiffman
Background: State-of-the-art cervical cancer prevention includes human papillomavirus (HPV) vaccination among adolescents and screening/treatment of cervical precancer (CIN3/AIS and, less strictly, CIN2) among adults. HPV testing provides sensitive detection of precancer but, to reduce overtreatment, secondary "triage" is needed to predict women at highest risk. Those with the highest-risk HPV types or abnormal cytology are commonly referred to colposcopy; however, expert cytology services are critically lacking in many regions...
April 11, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29602377/-the-spanish-society-of-cytology-quality-control-program-of-gynecological-cytology
#7
Francesc Alameda, Sonsoles Aso, Inmaculada Catalina, M Dolores Comes, M Carmen Gomez Mateo, Rosario Granados, Belén Lloveras, Rosa Oncins, Marta Rezola Bajineta, Francesc Treserra
INTRODUCTION: In Spain, the guidelines for cervical cancer screening include a recommendation to enroll in external quality control programs. The Spanish Society of Cytology (SEC) has initiated its own quality control program of gynecological cytology (QCPGC). AIM: To describe and discuss the results of the second round of SEĆs QCPGC. MATERIAL AND METHOD: The cases are selected by a group of expert cytologists. The cases with an agreement of 75% of four cytopathologists were used...
April 2018: Revista Española de Patología
https://www.readbyqxmd.com/read/29602143/2017-update-of-the-european-federation-for-colposcopy-efc-performance-standards-for-the-practice-of-colposcopy
#8
REVIEW
K Ulrich Petry, Pekka J Nieminen, Simon C Leeson, Christine O M A Bergeron, Charles W E Redman
A refinement of quality indicators (QIs) is described whereby the quality of care can be measured across colposcopy services in different countries and healthcare settings. A five-round Delphi process was conducted at successive satellite meetings from 2011 to 2015 of leading European colposcopists to refine the most high-scoring QIs relevant to colposcopic practice. A review and refinement of the wording of the standards and their criteria was undertaken by national society representatives. Six quality indicators were identified and refined...
May 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29597202/impact-of-implementing-100-rapid-review-as-a-quality-control-tool-in-cervical-cytology
#9
Juliana Cristina Magalhães, Cinara Zago Silveira Ázara, Sulene Brito do Nascimento Tavares, Edna Joana Claudio Manrique, Rita Goreti Amaral
OBJECTIVE: We aimed to evaluate the impact of implementing 100% rapid review (100% RR) as a quality control tool in cervical smear cytology. DESIGN: A cross-sectional study was conducted in which cytology findings, false-negative results, and quality indicators were evaluated. The variables were analyzed in 2004, the year in which 100% RR was implemented, and again in 2013, i.e., 10 years on. RESULTS: Detection of atypical squamous cells of undetermined significance (ASC-US) increased from 0...
2018: Acta Cytologica
https://www.readbyqxmd.com/read/29548787/inefficiencies-of-over-screening-and-under-screening-for-cervical-cancer-prevention-in-the-u-s
#10
Philip E Castle, Cosette M Wheeler, Nicole G Campos, Stephen Sy, Emily A Burger, Jane J Kim
There is limited information on the cost-inefficiencies of non-adherence to recommended cervical cancer screening or the potential value for improving non-adherence. We estimated the incremental value of adhering to recommended screening every three years with cytology, using a disease simulation model that integrated real-world screening practice data from New Mexico. The amount that can be spent to improve adherence was estimated by calculating the incremental net monetary benefit (INMB) under scenarios of Current Practice (assuming a population of mixed adherence) and Uniformly Non-Adherent populations with imperfect or perfect adherence to follow-up of screen-positive women...
June 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29543048/ensuring-patient-safety-when-implementing-a-new-diagnostic-pathway-for-thyroid-nodules
#11
M Brimioulle, A Al-Lami, S Marzouk, H Emerson, A Balfour, V Dhar, I J Nixon
Introduction The aim of this study was to determine whether ultrasound alone is sufficient to safely exclude malignancy in thyroid nodules in a district general hospital setting, to comply with the latest British Thyroid Association guidelines. Methods This retrospective study investigated the quality of ultrasound reporting and the correlation between ultrasound report and histology for individual thyroid nodules. Cases were selected from the thyroid multidisciplinary meeting and included all patients having undergone surgery for a thyroid malignancy in a one-year period...
May 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29528922/quality-improvement-to-demonstrate-the-lack-of-reliability-of-the-human-papillomavirus-mrna-assay-to-identify-women-with-latent-human-papillomavirus-infections
#12
Sarah Cotton, Robert E Brown, Elizabeth K Nugent, Sonia C Robazetti, Pamela D Berens, Judith A Smith
OBJECTIVE: To assess the consistency between human papillomavirus (HPV) mRNA testing in women with a history of previous HPV infections diagnosed by HPV DNA assay and the potential effects on follow-up HPV screening. METHODS: This was a quality improvement study that used data from a pathology laboratory software database reviewed from November 2014 to June 2016 to identify female patients aged 30 years or older with greater than one HPV-positive result, including one or more HPV mRNA assay results and one or more documented HPV DNA assay results for comparison...
April 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29505536/diagnostic-accuracy-of-colposcopy-with-dynamic-spectral-imaging-for-cytology-negative-high-risk-hpv-positive-failed-test-of-cure-after-large-loop-excision-of-the-transformation-zone-lletz-of-the-cervix-results-of-the-dysis-colposcopy-1-study
#13
Christina Founta, Emmanouil Papagiannakis, Nithya Ratnavelu, Arlene Feusi, Stavros Natsis, Melissa Bradbury, Ann Fisher, Raj Naik
After treatment for cervical intraepithelial neoplasia (CIN), in the UK women who are cytology-negative, high-risk (HR) human papilloma virus (HPV) positive are referred to colposcopy. This pilot study assessed the incidence of residual/recurrent CIN and the diagnostic accuracy of colposcopy with dynamic spectral imaging (DSI) mapping in their detection.This was a prospective service evaluation carried out in a UK National Health Service (NHS) colposcopy clinic. All women, referred with negative cytology/HR-HPV positive result following treatment for CIN from March 2013 until November 2014, who were examined with the DSI digital colposcope were included...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29478281/frequency-of-unsatisfactory-cervical-cytology-smears-in-cancer-screening-of-japanese-women-a-systematic-review-and-meta-analysis
#14
REVIEW
Satoyo Hosono, Teruhiko Terasawa, Takafumi Katayama, Seiju Sasaki, Keika Hoshi, Chisato Hamashima
The Bethesda system (TBS) has been used for cervical cytological diagnosis in Japan since 2008. Evaluation of specimen adequacy is the most important aspect of quality assurance and for precise diagnosis in TBS. A systematic review and meta-analysis were carried out to assess the unsatisfactory specimen rate in the primary cervical cancer screening setting in Japan. Ovid Medline and Ichushi-Web databases were searched from inception through to May 2017. Prospective and retrospective studies that reported the proportion of unsatisfactory specimens in healthy asymptomatic Japanese women in a cervical cancer screening program were eligible for inclusion; 17 studies were included in the meta-analysis...
April 2018: Cancer Science
https://www.readbyqxmd.com/read/29401497/a-novel-solution-configuration-on-liquid-based-endometrial-cytology
#15
COMPARATIVE STUDY
Shulan Lv, Rui Wang, Qi Wang, Lu Han, Xiaoqian Tuo, Huilian Hou, Yu Liu, Zan Shi, Qing Wang, Yan Li, Chao Sun, Xue Xue, Qiling Li
OBJECTIVE: Early detection and diagnosis of endometrial carcinoma and precancerous change would undoubtedly become the most alluring part for researchers. With the emergence of endometrial brush samplers, a new upsurge in endometrial cytology is in the making. But endometrial specimens obtained by the endometrial brush samplers require special preservation solution. The objective of this study is to develop a new kind of endometrial-cell preservation solution and to test the availability compared with a patented liquid-based cell preservation solution...
2018: PloS One
https://www.readbyqxmd.com/read/29394915/trend-analysis-of-the-quality-indicators-for-the-brazilian-cervical-cancer-screening-programme-by-region-and-state-from-2006-to-2013
#16
Ricardo Filipe Alves Costa, Adhemar Longatto-Filho, Fabiana de Lima Vazquez, Céline Pinheiro, Luiz Carlos Zeferino, José Humberto Tavares Guerreiro Fregnani
BACKGROUND: Quality indicators for the Brazilian cervical cancer screening programme can provide a perspective on its effectiveness in Brazilian macro-regions and states. The aim of this study was to perform a trend analysis of the cervical cancer screening program's quality indicators, according to Brazilian regions and states, from 2006 to 2013. METHODS: Using information from approximately 62,000,000 exams obtained from the Information System of Cervical Cancer Screening (SISCOLO), joinpoint analysis was used to calculate the Annual Percentage Change (APC)...
February 2, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29369251/community-based-screening-for-cervical-cancer-using-visual-inspection-with-acetic-acid-results-and-lessons-learned-from-a-pilot-study-in-vietnam
#17
Lan T H Vu, Hanh T D Tran, Binh Th Nguyen, Ha T T Bui, Anh Duy Nguyen, Nha Ba Pham
CONTEXT: Vietnam still applies the opportunistic cytology-based screening model, which failed to have an impact on the increasing burden of cervical cancer in Vietnam. OBJECTIVES: To pilot a community-based screening model for cervical cancer using visual inspection with acetic acid (VIA) in Vietnam by training midwife and assistant physician working at grassroots level of health care system. DESIGN: The study employed a pre-experimental design...
March 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29353972/accuracy-of-triage-strategies-for-human-papillomavirus-dna-positive-women-in-low-resource-settings-a-cross-sectional-study-in-china
#18
Margaret Wang, Shangying Hu, Shuang Zhao, Wenhua Zhang, Qinjing Pan, Xun Zhang, Feng Chen, Jinxiu Han, Junfei Ma, Jennifer S Smith, Youlin Qiao, Caihong Zhou, Fanghui Zhao
Objective: Care HPV is a human papillomavirus (HPV) DNA test for low-resource settings (LRS). This study assesses optimum triage strategies for care HPV-positive women in LRS. Methods: A total of 2,530 Chinese women were concurrently screened for cervical cancer with visual inspection with acetic acid (VIA), liquid-based cytology and HPV testing by physician- and self-collected care HPV, and physician-collected Hybrid Capture 2 (HC2). Screen-positive women were referred to colposcopy with biopsy and endocervical curettage as necessary...
December 2017: Chinese Journal of Cancer Research, Chung-kuo Yen Cheng Yen Chiu
https://www.readbyqxmd.com/read/29349795/quality-of-life-assumptions-determine-which-cervical-cancer-screening-strategies-are-cost-effective
#19
Inge M C M de Kok, Ida J Korfage, Wilbert B van den Hout, Theo J M Helmerhorst, J Dik F Habbema, Marie-Louise Essink-Bot, Marjolein van Ballegooijen
Quality-adjusted life years are used in cost-effectiveness analyses (CEAs). To calculate QALYs, a "utility" (0-1) is used for each health state induced or prevented by the intervention. We aimed to estimate the impact of quality of life (QoL) assumptions (utilities and durations of health states) on CEAs of cervical cancer screening. To do so, 12 alternative sets of utility assumptions were retrieved from published cervical cancer screening CEAs. Two additional sets were based on empirical QoL data that were integrally obtained through two different measures (SF-6D and EQ-5D) from eight groups of women (total n = 3,087), from invitation for screening to diagnosis with cervical cancer...
June 1, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29341505/stability-integrity-and-recovery-rate-of-cellular-nucleic-acids-preserved-in-a-new-liquid-based-cytology-medium
#20
Guodong Zhao, Zhaocheng Liu, Yaping Tian, Minsheng Zhu, Shouli Wang, Hui Wang, Shen Gao, Yong Ma, Minxue Zheng
BACKGROUND: Liquid-based cytology (LBC) has replaced the conventional Papanicolaou test in cervical cancer screening. The cervical swab specimens collected in LBC media can also be used for additional analyses including high-risk HPV (HR-HPV) test, DNA methylation analysis, and HPV E6/E7 mRNA test. METHODS: The stability, integrity, and recovery rate of cellular DNA and RNA after storage at different conditions were evaluated by a quantitative real-time PCR (qPCR) based HR-HPV test, reverse transcription qPCR (RT-qPCR), and agarose gel electrophoresis...
January 16, 2018: Diagnostic Cytopathology
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