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https://www.readbyqxmd.com/read/28610628/case-report-microcephaly-associated-with-zika-virus-infection-colombia
#1
Salim Mattar, Carolina Ojeda, Janna Arboleda, German Arrieta, Irene Bosch, Ingrid Botia, Nelson Alvis-Guzman, Carlos Perez-Yepes, Lee Gerhke, German Montero
BACKGROUND: Recently there has been a large outbreak of Zika virus infections in Colombia, South America. The epidemic began in September 2015 and continued to April 2017, for the total number of Zika cases reported of 107,870. For those confirmed Zika cases, there were nearly 20,000 (18.5%) suspected to be pregnant women, resulting in 157 confirmed cases of microcephaly in newborns reported by their health government agency. There is a clear under-estimation of the total number of cases and in addition no prior publications have been published to demonstrate the clinical aspects of the Zika infection in Colombia...
June 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28594771/serial-head-and-brain-imaging-of-17-fetuses-with-confirmed-zika-virus-infection-in-colombia-south-america
#2
Miguel Parra-Saavedra, Jennita Reefhuis, Juan Pablo Piraquive, Suzanne M Gilboa, Martina L Badell, Cynthia A Moore, Marcela Mercado, Diana Valencia, Denise J Jamieson, Mauricio Beltran, Magda Sanz-Cortes, Ana Maria Rivera-Casas, Mayel Yepez, Guido Parra, Martha Ospina Martinez, Margaret A Honein
OBJECTIVE: To evaluate fetal ultrasound and magnetic resonance imaging findings among a series of pregnant women with confirmed Zika virus infection to evaluate the signs of congenital Zika syndrome with respect to timing of infection. METHODS: We conducted a retrospective case series of pregnant women referred to two perinatal clinics in Barranquilla and Ibagué, Colombia, who had findings consistent with congenital Zika syndrome and Zika virus infection confirmed in maternal, fetal, or neonatal samples...
June 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28574621/prospects-for-induction-of-cd8-t-cell-mediated-immunity-to-zika-virus-infection-by-yellow-fever-virus-yfv-vaccination
#3
Kim Blom, John Tyler Sandberg, Karin Loré, Hans-Gustaf Ljunggren
The Zika virus epidemic represents an unprecedented health crisis affecting significant parts of the world (1) . On February 1(st) 2016, the WHO declared the reported clusters of Zika-virus induced microcephaly and other neurological disorders a Public Health Emergency of International Concern (PHEIC). The epidemic is currently ongoing in Latin America and the Caribbean, with impacts of the infection already seen in large populations of Brazil, Colombia, Mexico, Peru and beyond. No specific treatment or vaccine is available, although several candidates are under development (2) ...
June 2, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28566102/real-time-parameter-estimation-of-zika-outbreaks-using-model-averaging
#4
C R Sebrango-Rodríguez, D A Martínez-Bello, L Sánchez-Valdés, P J Thilakarathne, E Del Fava, P VAN DER Stuyft, A López-Quílez, Z Shkedy
Early prediction of the final size of any epidemic and in particular for Zika disease outbreaks can be useful for health authorities in order to plan the response to the outbreak. The Richards model is often been used to estimate epidemiological parameters for arboviral diseases based on the reported cumulative cases in single- and multi-wave outbreaks. However, other non-linear models can also fit the data as well. Typically, one follows the so called post selection estimation procedure, i.e., selects the best fitting model out of the set of candidate models and ignores the model uncertainty in both estimation and inference since these procedures are based on a single model...
June 1, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28538734/zika-virus-evolution-and-spread-in-the-americas
#5
Hayden C Metsky, Christian B Matranga, Shirlee Wohl, Stephen F Schaffner, Catherine A Freije, Sarah M Winnicki, Kendra West, James Qu, Mary Lynn Baniecki, Adrianne Gladden-Young, Aaron E Lin, Christopher H Tomkins-Tinch, Simon H Ye, Daniel J Park, Cynthia Y Luo, Kayla G Barnes, Rickey R Shah, Bridget Chak, Giselle Barbosa-Lima, Edson Delatorre, Yasmine R Vieira, Lauren M Paul, Amanda L Tan, Carolyn M Barcellona, Mario C Porcelli, Chalmers Vasquez, Andrew C Cannons, Marshall R Cone, Kelly N Hogan, Edgar W Kopp, Joshua J Anzinger, Kimberly F Garcia, Leda A Parham, Rosa M Gélvez Ramírez, Maria C Miranda Montoya, Diana P Rojas, Catherine M Brown, Scott Hennigan, Brandon Sabina, Sarah Scotland, Karthik Gangavarapu, Nathan D Grubaugh, Glenn Oliveira, Refugio Robles-Sikisaka, Andrew Rambaut, Lee Gehrke, Sandra Smole, M Elizabeth Halloran, Luis Villar, Salim Mattar, Ivette Lorenzana, Jose Cerbino-Neto, Clarissa Valim, Wim Degrave, Patricia T Bozza, Andreas Gnirke, Kristian G Andersen, Sharon Isern, Scott F Michael, Fernando A Bozza, Thiago M L Souza, Irene Bosch, Nathan L Yozwiak, Bronwyn L MacInnis, Pardis C Sabeti
Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects have attracted a great deal of attention, much remains unknown about ZIKV disease epidemiology and ZIKV evolution, in part owing to a lack of genomic data. Here we address this gap in knowledge by using multiple sequencing approaches to generate 110 ZIKV genomes from clinical and mosquito samples from 10 countries and territories, greatly expanding the observed viral genetic diversity from this outbreak. We analysed the timing and patterns of introductions into distinct geographic regions; our phylogenetic evidence suggests rapid expansion of the outbreak in Brazil and multiple introductions of outbreak strains into Puerto Rico, Honduras, Colombia, other Caribbean islands, and the continental United States...
June 15, 2017: Nature
https://www.readbyqxmd.com/read/28487212/mapping-the-ecoepidemiology-of-zika-virus-infection-in-urban-and-rural-areas-of-pereira-risaralda-colombia-2015-2016-implications-for-public-health-and-travel-medicine
#6
Alfonso J Rodriguez-Morales, Pablo Ruiz, Javier Tabares, Carlos Augusto Ossa, Maria Camila Yepes-Echeverry, Valeria Ramirez-Jaramillo, Maria Leonor Galindo-Marquez, Carlos Julian García-Loaiza, Juan Alejandro Sabogal-Roman, Esteban Parra-Valencia, Guillermo J Lagos-Grisales, Carlos O Lozada-Riascos, Cornelis A de Pijper, Martin P Grobusch
OBJECTIVE: Geographical information systems (GIS) have been demonstrated earlier to be of great use to inform public health action against vector-borne infectious diseases. METHODS: Using surveillance data on the ongoing ZIKV outbreak from Pereira, Colombia (2015-2016), we estimated incidence rates (cases/100,000 population), and developed maps correlating with the ecoepidemiology of the area. RESULTS: Up to October 8, 2016, 439 cases of ZIKV were reported in Pereira (93 cases/100,000 pop...
May 6, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28418539/ophthalmic-manifestations-of-congenital-zika-syndrome-in-colombia-and-venezuela
#7
Juan B Yepez, Felipe A Murati, Michele Pettito, Carlos F Peñaranda, Jazmin de Yepez, Gladys Maestre, J Fernando Arevalo
Importance: The ocular manifestations and sequelae of Zika virus infection are not well known. Recently, the World Health Organization changed the declaration of Zika as a public health emergency and designated the viral outbreak and related microcephaly clusters as a long-term program of work. This change indicates the urgent need to evaluate and document ophthalmic manifestations in patients for timely management of this disease. In addition, confirmation whether the public health problem in Brazil extends to other regions in South America is needed...
May 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28348794/zika-and-chikungunya-virus-co-infection-in-a-traveller-returning-from-colombia-2016-virus-isolation-and-genetic-analysis
#8
Kartikeya Cherabuddi, Nicole M Iovine, Kairav Shah, Sarah K White, Taylor Paisie, Marco Salemi, J Glenn Morris, John A Lednicky
INTRODUCTION: Zikavirus (ZIKV) and Chikungunyavirus (CHIKV) can share the same mosquito vector, and co-infections by these viruses can occur in humans. While infections with these viruses share commonalities, CHIKV is unique in causing arthritis and arthralgias that may persist for a year or more. These infections are commonly diagnosed by RT-PCR-based methods during the acute phase of infection. Even with the high specificity and sensitivity characteristic of PCR, false negatives can occur, highlighting the need for additional diagnostic methods for confirmation...
December 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28344900/temporal-patterns-and-geographic-heterogeneity-of-zika-virus-zikv-outbreaks-in-french-polynesia-and-central-america
#9
Ying-Hen Hsieh
BACKGROUND: Zika virus (ZIKV) transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO) to declare ZIKV as a Public Health Emergency of International Concern in February 2016, due to its strong association with medical complications such as microcephaly and Guillain-Barré Syndrome (GBS). However, a substantial gap in knowledge still exists regarding differing temporal pattern and potential of transmission of ZIKV in different regions of the world...
2017: PeerJ
https://www.readbyqxmd.com/read/28335029/the-challenge-of-assessing-microcephaly-in-the-context-of-the-zika-virus-epidemic
#10
Llorenç Quintó, Alberto L García-Basteiro, Azucena Bardají, Raquel González, Norma Padilla, Flor E Martinez-Espinosa, Myriam Arévalo-Herrera, Eusébio Macete, Clara Menéndez
The present article examines the impact of the current limitations of the microcephaly definition in the context of the Zika virus outbreak. It highlights its dependence on the method used for determining gestational age and other anthropometric parameters, and includes original results of prevalence of microcephaly in four countries from two different continents (Mozambique, Brazil, Guatemala and Colombia). Alternative definitions of microcephaly are proposed to allow the identification of true cases of microcephaly in a more accurate manner...
March 10, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28325935/a-comparison-study-of-zika-virus-outbreaks-in-french-polynesia-colombia-and-the-state-of-bahia-in-brazil
#11
Daihai He, Daozhou Gao, Yijun Lou, Shi Zhao, Shigui Ruan
Zika virus (ZIKV) disease outbreaks occurred in French Polynesia in 2013-2014 and in Brazil and Colombia in 2015-2016, respectively. Using our recently developed ZIKV disease model, we simulated the reported ZIKV infection cases from French Polynesia, Colombia and the State of Bahia of Brazil. Moreover, we estimated that the infection attack rates were 78.0% (95% confidence interval (CI): 63.5-86.3%) in French Polynesia which closely matches a previous serological study; 20.8% (95% CI: 1.1-50.0%) in Colombia which suggests that the attack rate was most likely less than 50%; and 32...
March 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28296632/severe-neurologic-disorders-in-2-fetuses-with-zika-virus-infection-colombia
#12
Jorge Acosta-Reyes, Edgar Navarro, Maria José Herrera, Eloina Goenaga, Martha L Ospina, Edgar Parra, Marcela Mercado, Pablo Chaparro, Mauricio Beltran, Maria Luz Gunturiz, Lissethe Pardo, Catalina Valencia, Sandra Huertas, Jorge Rodríguez, Germán Ruiz, Diana Valencia, Lisa B Haddad, Sarah C Tinker, Cynthia A Moore, Hernando Baquero
We report the results of pathologic examinations of 2 fetuses from women in Colombia with Zika virus infection during pregnancy that revealed severe central nervous system defects and potential associated abnormalities of the eye, spleen, and placenta. Amniotic fluid and tissues from multiple fetal organs tested positive for Zika virus.
June 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28074128/epidemic-outbreak-of-chikungunya-in-two-neighboring-towns-in-the-colombian-caribbean-a-survival-analysis
#13
Misael Oviedo-Pastrana, Nelson Méndez, Salim Mattar, Germán Arrieta, Luty Gomezcaceres
BACKGROUND: The first autochthonous Chikungunya virus transmission in Colombia was reported in September 2014. Three months later, every town in the Caribbean region was affected, including the bordering towns of Ovejas and Corozal, in the department of Sucre. The objective of the study was to analyze and compare the temporal dynamics of the outbreak of Chikungunya in two towns of the department of Sucre. METHODS: Households with suspicious cases with clinical symptomatology for Chikungunya were enrolled...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28062188/a-comprehensive-analysis-and-immunobiology-of-autoimmune-neurological-syndromes-during-the-zika-virus-outbreak-in-c%C3%A3%C2%BAcuta-colombia
#14
Juan-Manuel Anaya, Yhojan Rodríguez, Diana M Monsalve, Daniel Vega, Ernesto Ojeda, Diana González-Bravo, Mónica Rodríguez-Jiménez, Carlos A Pinto-Díaz, Pablo Chaparro, María L Gunturiz, Aftab A Ansari, M Eric Gershwin, Nicolás Molano-González, Carolina Ramírez-Santana, Yeny Acosta-Ampudia
We have focused on the epidemiology and immunobiology of Zika virus (ZIKV) infection and factors associated with the development of Guillain-Barré syndrome (GBS) and other neurological syndromes in Cúcuta, the capital of North Santander department, Colombia. Data of patients with ZIKV disease reported to the national population-based surveillance system were used to calculate the basic reproduction number (R0) and the attack rates (ARs) as well as to develop epidemiological maps. Patients with neurological syndromes were contacted and their diagnoses were confirmed...
February 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/27977645/preliminary-report-of-microcephaly-potentially-associated-with-zika-virus-infection-during-pregnancy-colombia-january-november-2016
#15
Esther Liliana Cuevas, Van T Tong, Nathaly Rozo, Diana Valencia, Oscar Pacheco, Suzanne M Gilboa, Marcela Mercado, Christina M Renquist, Maritza González, Elizabeth C Ailes, Carolina Duarte, Valerie Godoshian, Christina L Sancken, Angelica Maria Rico Turca, Dinorah L Calles, Martha Ayala, Paula Morgan, Erika Natalia Tolosa Perez, Hernan Quijada Bonilla, Ruben Caceres Gomez, Ana Carolina Estupiñan, Maria Luz Gunturiz, Dana Meaney-Delman, Denise J Jamieson, Margaret A Honein, Martha Lucia Ospina Martínez
In Colombia, approximately 105,000 suspected cases of Zika virus disease (diagnosed based on clinical symptoms, regardless of laboratory confirmation) were reported during August 9, 2015-November 12, 2016, including nearly 20,000 in pregnant women (1,2). Zika virus infection during pregnancy is a known cause of microcephaly and serious congenital brain abnormalities and has been associated with other birth defects related to central nervous system damage (3). Colombia's Instituto Nacional de Salud (INS) maintains national surveillance for birth defects, including microcephaly and other central nervous system defects...
December 16, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27869391/-first-report-of-the-f1534c-mutation-associated-with-cross-resistance-to-ddt-and-pyrethroids-in-aedes-aegypti-from-colombia
#16
María Claudia Atencia, María De Jesús Pérez, María Cristina Jaramillo, Sandy Milena Caldera, Suljey Cochero, Eduar Elías Bejarano
The main strategy for the control of Aedes aegypti, vector of dengue, chikungunya and Zika viruses, is based on the use of insecticides to reduce its populations. However, their use has led to insect resistance to these chemicals. Objective: To determine the presence of the F1534C mutation associated with cross-resistance to DDT and pyrethroids in A. aegypti in Sincelejo, Colombia. Materials and methods: We studied nine specimens of A. aegypti that showed resistance to lambdacyhalothrin in bioassays developed by the Secretaría de Salud de Sucre...
September 1, 2016: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/27846442/estimate-of-the-reproduction-number-of-the-2015-zika-virus-outbreak-in-barranquilla-colombia-and-estimation-of-the-relative-role-of-sexual-transmission
#17
Sherry Towers, Fred Brauer, Carlos Castillo-Chavez, Andrew K I Falconar, Anuj Mubayi, Claudia M E Romero-Vivas
BACKGROUND: In 2015, the Zika arbovirus (ZIKV) began circulating in the Americas, rapidly expanding its global geographic range in explosive outbreaks. Unusual among mosquito-borne diseases, ZIKV has been shown to also be sexually transmitted, although sustained autochthonous transmission due to sexual transmission alone has not been observed, indicating the reproduction number (R0) for sexual transmission alone is less than 1. Critical to the assessment of outbreak risk, estimation of the potential attack rates, and assessment of control measures, are estimates of the basic reproduction number, R0...
December 2016: Epidemics
https://www.readbyqxmd.com/read/27743683/initial-experience-with-imported-zika-virus-infection-in-spain
#18
Marta Díaz-Menéndez, Fernando de la Calle-Prieto, Dolores Montero, Eugenia Antolín, Ana Vazquez, Marta Arsuaga, Elena Trigo, Silvia García-Bujalance, María de la Calle, Paz Sánchez Seco, Fernando de Ory, Jose Ramón Arribas
INTRODUCTION: A considerable increase of imported Zika virus (ZIKV) infection has been reported in Europe in the last year. This is the result of the large outbreak of the disease in the Americas, along with the increase in the numbers of travellers and immigrants arriving from ZIKV endemic areas. METHODS: A descriptive study was conducted in the Tropical Medicine Unit of Hospital La Paz-Carlos III in Madrid on travellers returning from an endemic area for ZIKV from January to April 2016...
October 12, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27743307/mapping-zika-virus-disease-incidence-in-valle-del-cauca
#19
Alfonso J Rodriguez-Morales, Maria Leonor Galindo-Marquez, Carlos Julian García-Loaiza, Juan Alejandro Sabogal-Roman, Santiago Marin-Loaiza, Andrés F Ayala, Guillermo J Lagos-Grisales, Carlos O Lozada-Riascos, Esteban Parra-Valencia, Jorge H Rojas-Palacios, Eduardo López, Pío López, Martin P Grobusch
OBJECTIVE: Geographical information systems (GIS) use for development of epidemiological maps in tropical diseases is increasingly frequently utilized. Here, we apply this technique to map the current Zika virus (ZIKV) outbreak in Colombia. METHODS: Surveillance cases data of the ongoing epidemic of ZIKV in Valle del Cauca department and its capital, Cali (2015-2016), were used to estimate cumulated incidence rates (cases/100,000 population) to develop the first maps in the department and it municipalities...
February 2017: Infection
https://www.readbyqxmd.com/read/27705091/guillain-barr%C3%A3-syndrome-associated-with-zika-virus-infection-in-colombia
#20
Beatriz Parra, Jairo Lizarazo, Jorge A Jiménez-Arango, Andrés F Zea-Vera, Guillermo González-Manrique, José Vargas, Jorge A Angarita, Gonzalo Zuñiga, Reydmar Lopez-Gonzalez, Cindy L Beltran, Karen H Rizcala, Maria T Morales, Oscar Pacheco, Martha L Ospina, Anupama Kumar, David R Cornblath, Laura S Muñoz, Lyda Osorio, Paula Barreras, Carlos A Pardo
BACKGROUND: Zika virus (ZIKV) infection has been linked to the Guillain-Barré syndrome. From November 2015 through March 2016, clusters of cases of the Guillain-Barré syndrome were observed during the outbreak of ZIKV infection in Colombia. We characterized the clinical features of cases of Guillain-Barré syndrome in the context of this ZIKV infection outbreak and investigated their relationship with ZIKV infection. METHODS: A total of 68 patients with the Guillain-Barré syndrome at six Colombian hospitals were evaluated clinically, and virologic studies were completed for 42 of the patients...
October 20, 2016: New England Journal of Medicine
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