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https://www.readbyqxmd.com/read/29665783/surveillance-on-the-endemic-of-zika-virus-infection-by-meteorological-factors-in-colombia-a-population-based-spatial-and-temporal-study
#1
Lung-Chang Chien, Ro-Ting Lin, Yunqi Liao, Francisco S Sy, Adriana Pérez
BACKGROUND: Zika virus (ZIKV) infection is a pandemic and a public health emergency. It is transmitted by mosquitoes, primarily the Aedes genus. In light of no treatment currently, it is crucial to develop effective vector control programs to prevent the spread of ZIKV infection earlier when observing possible risk factors, such as weather conditions enhancing mosquito breeding and surviving. METHODS: This study collected daily meteorological measurements and weekly ZIKV infectious cases among 32 departments of Colombia from January 2015-December 2016...
April 17, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29627357/estimating-the-numbers-of-pregnant-women-infected-with-zika-virus-and-infants-with-congenital-microcephaly-in-colombia-2015-2017
#2
Alys Adamski, Jeanne Bertolli, Carlos Castañeda-Orjuela, Owen J Devine, Michael A Johansson, Maritza Adegnis Gonzalez Duarte, Sarah C Tinker, Sherry L Farr, Marcela Maria Mercado Reyes, Van T Tong, Oscar Eduardo Pacheco Garcia, Diana Valencia, Diego Alberto Cuellar Ortiz, Margaret A Honein, Denise J Jamieson, Martha Lucía Ospina Martínez, Suzanne M Gilboa
BACKGROUND: Colombia experienced a Zika virus (ZIKV) outbreak in 2015-2016. To assist with planning for medical and supportive services for infants affected by prenatal ZIKV infection, we used a model to estimate the number of pregnant women infected with ZIKV and the number of infants with congenital microcephaly from August 2015- August 2017. METHODS: We used nationally-reported cases of symptomatic ZIKV disease among pregnant women and information from the literature on the percent of asymptomatic infections to estimate the number of pregnant women with ZIKV infection occurring August 2015 - December 2016...
April 5, 2018: Journal of Infection
https://www.readbyqxmd.com/read/29579112/maternal-invasion-history-of-aedes-aegypti-and-aedes-albopictus-into-the-isthmus-of-panama-implications-for-the-control-of-emergent-viral-disease-agents
#3
Gilberto A Eskildsen, Jose R Rovira, Octavio Smith, Matthew J Miller, Kelly L Bennett, W Owen McMillan, Jose Loaiza
Despite an increase in dengue outbreaks and the arrival of chikungunya and Zika disease in Panama, studies on the demographic history of the invasive Aedes mosquitoes that are the principle vectors of these diseases are still lacking in this region. Here, we assess the genetic diversity of these mosquitoes in order to decipher their invasion histories into the Isthmus of Panama. DNA sequences from the mitochondrial cytochrome C oxidase I gene obtained from 30 localities in 10 provinces confirmed the presence of more than one mitochondrial haplogroup (i...
2018: PloS One
https://www.readbyqxmd.com/read/29512482/the-burden-of-dengue-fever-and-chikungunya-in-southern-coastal-ecuador-epidemiology-clinical-presentation-and-phylogenetics-from-the-first-two-years-of-a-prospective-study
#4
Anna M Stewart-Ibarra, Sadie J Ryan, Aileen Kenneson, Christine A King, Mark Abbott, Arturo Barbachano-Guerrero, Efraín Beltrán-Ayala, Mercy J Borbor-Cordova, Washington B Cárdenas, Cinthya Cueva, Julia L Finkelstein, Christina D Lupone, Richard G Jarman, Irina Maljkovic Berry, Saurabh Mehta, Mark Polhemus, Mercy Silva, Timothy P Endy
Here, we report the findings from the first 2 years of an arbovirus surveillance study conducted in Machala, Ecuador, a dengue-endemic region (2014-2015). Patients with suspected dengue virus (DENV) infections (index cases, N = 324) were referred from five Ministry of Health clinical sites. A subset of DENV-positive index cases ( N = 44) were selected, and individuals from the index household and four neighboring homes within 200 m were recruited ( N = 400). Individuals who entered the study, other than the index cases, are referred to as associates...
March 5, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29382300/co-circulation-and-simultaneous-co-infection-of-dengue-chikungunya-and-zika-viruses-in-patients-with-febrile-syndrome-at-the-colombian-venezuelan-border
#5
Marlen Yelitza Carrillo-Hernández, Julian Ruiz-Saenz, Lucy Jaimes Villamizar, Sergio Yebrail Gómez-Rangel, Marlen Martínez-Gutierrez
BACKGROUND: In Colombia, the dengue virus (DENV) has been endemic for decades, and with the recent entry of the chikungunya virus (CHIKV) (2014) and the Zika virus (ZIKV) (2015), health systems are overloaded because the diagnosis of these three diseases is based on clinical symptoms, and the three diseases share a symptomatology of febrile syndrome. Thus, the objective of this study was to use molecular methods to identify their co-circulation as well as the prevalence of co-infections, in a cohort of patients at the Colombian-Venezuelan border...
January 30, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29362446/critical-neutralizing-fragment-of-zika-virus-ediii-elicits-cross-neutralization-and-protection-against-divergent-zika-viruses
#6
Wanbo Tai, Lei He, Yufei Wang, Shihun Sun, Guangyu Zhao, Chuming Luo, Pei Li, Haiyan Zhao, Daved H Fremont, Fang Li, Shibo Jiang, Yusen Zhou, Lanying Du
Zika virus (ZIKV) infection remains a serious health threat due to its close association with congenital Zika syndrome (CZS), which includes microcephaly and other severe birth defects. As no vaccines are available for human use, continuous effort is needed to develop effective and safe vaccines to prevent ZIKV infection. In this study, we constructed three recombinant proteins comprising, respectively, residues 296-406 (E296-406), 298-409 (E298-409), and 301-404 (E301-404) of ZIKV envelope (E) protein domain III (EDIII) fused with a C-terminal Fc of human IgG...
January 24, 2018: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/29353032/clinical-assessment-and-brain-findings-in-a-cohort-of-mothers-fetuses-and-infants-infected-with-zika-virus
#7
Magdalena Sanz Cortes, Ana Maria Rivera, Mayel Yepez, Carolina V Guimaraes, Israel Diaz Yunes, Alexander Zarutskie, Ivan Davila, Anil Shetty, Arun Mahadev, Saray Maria Serrano, Nicolas Castillo, Wesley Lee, Gregory Valentine, Michael Belfort, Guido Parra, Carrie Mohila, Kjersti Aagaard, Miguel Parra Saavedra
BACKGROUND: Congenital Zika virus (ZIKV) infection can be detected in both the presence and absence of microcephaly and manifests as a number of signs and symptoms that are detected clinically and by neuroimaging. However, to date, qualitative and quantitative measures for the purpose of diagnosis and prognosis are limited. OBJECTIVES: Main objectives of this study conducted on fetuses and infants with confirmed congenital Zika virus infection and detected brain abnormalities were (1) to assess the prevalence of microcephaly and the frequency of the anomalies that include a detailed description based on ultrasound and magnetic resonance imaging in fetuses and ultrasound, magnetic resonance imaging, and computed tomography imaging postnatally, (2) to provide quantitative measures of fetal and infant brain findings by magnetic resonance imaging with the use of volumetric analyses and diffusion-weighted imaging, and (3) to obtain additional information from placental and fetal histopathologic assessments and postnatal clinical evaluations...
April 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29177397/-not-everything-is-zika-congenital-toxoplasmosis-still-prevalent-in-colombia
#8
Jorge L Alvarado-Socarras, Keyla Meneses-Silvera, Andrea Carolina Zarate-Vergara, Carlos Guerrero-Gomez, Alfonso J Rodriguez-Morales
Congenital toxoplasmosis continues to be a public health threat. Even existing guidelines, publicly known, its implementation and lack of appropriate interpretation of serological tests in pregnancy is often observed. This leds to failure in opportunities for positive and known interventions to decrease the fetal risk due to Toxoplasma gondii infection. We reported herein a case series, with variable neurological and systemic compromise (respiratory distress, hepatosplenomegaly, enterocolitis, brain calcifications, thrombocytopenia, ascites, shock), even fatal, calling for awareness about the fact that despite the Zika epidemics in 2015-2016 in Brazil, Colombia and other countries, precisely toxoplasmosis, is a differential diagnosis still prevalent in these territories, that can leds to severe consequences, with neurological disability and risk of ocular damage, even lately...
April 2017: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/29165933/transmission-scenarios-of-major-vector-borne-diseases-in-colombia-1990-2016
#9
Julio César Padilla, Fredy Eberto Lizarazo, Olga Lucía Murillo, Fernando Antonio Mendigaña, Edwin Pachón, Mauricio Javier Vera
Introducción. Las enfermedades transmitidas por vectores representan más de 17 % de todas las enfermedades infecciosas y causan anualmente un millón de defunciones a nivel mundial. En Colombia, la malaria, el dengue, la enfermedad de Chagas y las leishmaniasis son condiciones endemoepidémicas persistentes.Objetivo. Determinar el comportamiento epidemiológico de las enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016.Materiales y métodos. Se hizo un estudio descriptivo del comportamiento epidemiológico de las principales enfermedades transmitidas por vectores en zonas urbanas y rurales de Colombia entre 1990 y 2016, con la información proveniente de fuentes oficiales secundarias...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29161485/aedes-albopictus-skuse-1894-infected-with-the-american-asian-genotype-of-dengue-type-2-virus-in-medell%C3%A3-n-suggests-its-possible-role-as-vector-of-dengue-fever-in-colombia
#10
Andrés Gómez-Palacio, Juan Suaza-Vasco, Sandra Castaño, Omar Triana, Sandra Uribe
INTRODUCTION: Aedes aegypti and Ae. albopictus are recognized vectors of dengue, yellow fever, chikungunya and Zika arboviruses in several countries worldwide. In Colombia, Ae. albopictus geographical distribution has increased to include highly populated cities such as Cali and Medellín. Although this species has been frequently found in urban and semi-urban zones in the country, its role as vector of the dengue fever is poorly known. OBJECTIVE: To identify the presence of Ae...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29118981/zika-virus-disease-microcephaly-and-guillain-barr%C3%A3-syndrome-in-colombia-epidemiological-situation-during-21-months-of-the-zika-virus-outbreak-2015-2017
#11
Nelson Méndez, Misael Oviedo-Pastrana, Salim Mattar, Isaac Caicedo-Castro, German Arrieta
Background: The Zika virus disease (ZVD) has had a huge impact on public health in Colombia for the numbers of people affected and the presentation of Guillain-Barre syndrome (GBS) and microcephaly cases associated to ZVD. Methods: A retrospective descriptive study was carried out, we analyze the epidemiological situation of ZVD and its association with microcephaly and GBS during a 21-month period, from October 2015 to June 2017. The variables studied were: (i) ZVD cases, (ii) ZVD cases in pregnant women, (iii) laboratory-confirmed ZVD in pregnant women, (iv) ZVD cases associated with microcephaly, (v) laboratory-confirmed ZVD associated with microcephaly, and (vi) ZVD associated to GBS cases...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28991697/zika-virus-disease-associated-guillain-barr%C3%A3-syndrome-barranquilla-colombia-2015-2016
#12
Jorge L Salinas, Diana M Walteros, Ashley Styczynski, Flavio Garzón, Hernán Quijada, Elsa Bravo, Pablo Chaparro, Javier Madero, Jorge Acosta-Reyes, Jeremy Ledermann, Zuleima Arteta, Erin Borland, Paul Burns, Maritza Gonzalez, Ann M Powers, Marcela Mercado, Alma Solano, James J Sejvar, Martha L Ospina
BACKGROUND: An outbreak of Guillain-Barré syndrome (GBS), a disorder characterized by acute, symmetric limb weakness with decreased or absent deep-tendon reflexes, was reported in Barranquilla, Colombia, after the introduction of Zika virus in 2015. We reviewed clinical data for GBS cases in Barranquilla and performed a case-control investigation to assess the association of suspect and probable Zika virus disease with GBS. METHODS: We used the Brighton Collaboration Criteria to confirm reported GBS patients in Barranquilla during October 2015-April 2016...
October 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28975230/ocular-histopathologic-features-of-congenital-zika-syndrome
#13
Maria P Fernandez, Edgar Parra Saad, Martha Ospina Martinez, Sheryl Corchuelo, Marcela Mercado Reyes, Maria Jose Herrera, Miguel Parra Saavedra, Angelica Rico, Angela M Fernandez, Richard K Lee, Camila V Ventura, Audina M Berrocal, Sander R Dubovy
Importance: Congenital Zika syndrome (CZS) is known to be associated with severe malformations in newborns. Although microcephaly is the hallmark of this disease, the ocular findings are important given the severe visual impairment that has been observed in these patients. Regardless of the increased number of CZS cases reported, to date, no studies have described the ocular histopathologic findings of this entity. Objectives: To evaluate the presence of Zika virus (ZIKV) antigens and describe the associated ocular histopathologic features of 4 cases of CZS...
November 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28956541/spatial-distribution-of-zika-virus-infection-in-northeastern-colombia
#14
Alfonso J Rodriguez-Morales, Ubydul Haque, Jacob Ball, Carlos Julian García-Loaiza, Maria Leonor Galindo-Marquez, Juan Alejandro Sabogal-Roman, Santiago Marin-Loaiza, Andrés Felipe Ayala, Carlos O Lozada-Riascos, Fredi A Diaz-Quijano, Jorge L Alvarado-Socarras
In this study, we investigated the weekly reported spatio-temporal distribution and topographic risk factors for Zika virus (ZIKV) infection in northeastern Colombia. Weekly reported surveillance data, including clinical, suspected and confirmed cases from the ongoing ZIKV epidemic in the Santander and Norte de Santander departments (Santanderes) in Colombia were used to estimate cumulative incidence rates. Spatial analysis was performed to develop hot spot maps and to identify spatial topographic risk factors for infection...
September 1, 2017: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/28914749/raised-frequency-of-microcephaly-related-to-zika-virus-infection-in-two-birth-defects-surveillance-systems-in-bogot%C3%A3-and-cali-colombia
#15
Paula Hurtado-Villa, Angie K Puerto, Salomé Victoria, Gloria Gracia, Lesly Guasmayán, Patricia Arce, Gilberto Álvarez, Esperanza Blandón, Nubia Rengifo, Jorge A Holguín, Alexander Durán, Ignacio Zarante
Zika virus infection during pregnancy is now known to cause congenital microcephaly and severe brain defects. In 2016, rates of microcephaly appeared to start increasing around May, peaking in July, and declining through December. The occurrence of microcephaly appears to have increased nearly 4-fold in 2 large cities in Colombia, concurrently with the reported Zika virus epidemic in the country.
October 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28854106/mosquito-vector-biology-and-control-in-latin-america-a-27th-symposium
#16
Lee W Cohnstaedt, Catalina Alfonso-Parra, Ildefonso Fernandez-Salas
The 27th Annual Latin American Symposium presented by the American Mosquito Control Association (AMCA) was held as part of the 83rd Annual Meeting of the AMCA in San Diego, CA, in February 2017. The Latin American Symposia promote the participation of vector control specialists, public health workers, and academicians from Latin America and the sharing of data between continents. Generally, presentations are in Spanish and simultaneously translated in English, although the majority of PowerPoint slides are in English so all meeting attendees can understand the content...
September 2017: Journal of the American Mosquito Control Association
https://www.readbyqxmd.com/read/28829235/taking-innovative-vector-control-interventions-in-urban-latin-america-to-scale-lessons-learnt-from-multi-country-implementation-research
#17
Juliana Quintero, Tatiana García-Betancourt, Andrea Caprara, Cesar Basso, Elsa Garcia da Rosa, Pablo Manrique-Saide, Giovanini Coelho, Gustavo Sánchez-Tejeda, Felipe Dzul-Manzanilla, Diego Alejandro García, Gabriel Carrasquilla, Eduardo Alfonso-Sierra, Cyntia Monteiro Vasconcelos Motta, Johannes Sommerfeld, Axel Kroeger
Prior to the current public health emergency following the emergence of chikungunya and Zika Virus Disease in the Americas during 2014 and 2015, multi-country research investigated between 2011 and 2013 the efficacy of novel Aedes aegypti intervention packages through cluster randomised controlled trials in four Latin-American cities: Fortaleza (Brazil); Girardot (Colombia), Acapulco (Mexico) and Salto (Uruguay). Results from the trials led to a scaling up effort of the interventions at city levels. Scaling up refers to deliberate efforts to increase the impact of successfully tested health interventions to benefit more people and foster policy and program development in a sustainable way...
September 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28806479/zika-virus-disease-in-children-in-colombia-august-2015-to-may-2016
#18
Natalia Tolosa, Sarah C Tinker, Oscar Pacheco, Diana Valencia, Daniela Salas Botero, Van T Tong, Marcela Mercado, Suzanne M Gilboa, Maritza Gonzalez, Christina A Nelson, Lissethe Pardo, Carol Y Rao, Angélica Rico, Meredith Moore, Edgar Parra, Margaret A Honein, Martha L Ospina Martínez
BACKGROUND: Children are considered a potentially vulnerable population for Zika virus infection. However, data on paediatric Zika virus infection are sparse. METHODS: We analysed data from Colombia's national surveillance system during the 2015-2016 Zika virus outbreak on patients meeting the clinical case definition of Zika virus disease (ZVD) among children aged 1 month to 18 years to estimate incidence by demographic characteristics and characterize the occurrence of selected complications...
August 14, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28803069/estimating-the-reproductive-number-total-outbreak-size-and-reporting-rates-for-zika-epidemics-in-south-and-central-america
#19
Deborah P Shutt, Carrie A Manore, Stephen Pankavich, Aaron T Porter, Sara Y Del Valle
As South and Central American countries prepare for increased birth defects from Zika virus outbreaks and plan for mitigation strategies to minimize ongoing and future outbreaks, understanding important characteristics of Zika outbreaks and how they vary across regions is a challenging and important problem. We developed a mathematical model for the 2015/2016 Zika virus outbreak dynamics in Colombia, El Salvador, and Suriname. We fit the model to publicly available data provided by the Pan American Health Organization, using Approximate Bayesian Computation to estimate parameter distributions and provide uncertainty quantification...
December 2017: Epidemics
https://www.readbyqxmd.com/read/28767730/community-context-and-sub-neighborhood-scale-detail-to-explain-dengue-chikungunya-and-zika-patterns-in-cali-colombia
#20
Amy R Krystosik, Andrew Curtis, Paola Buritica, Jayakrishnan Ajayakumar, Robert Squires, Diana Dávalos, Robinson Pacheco, Madhav P Bhatta, Mark A James
BACKGROUND: Cali, Colombia has experienced chikungunya and Zika outbreaks and hypoendemic dengue. Studies have explained Cali's dengue patterns but lack the sub-neighborhood-scale detail investigated here. METHODS: Spatial-video geonarratives (SVG) with Ministry of Health officials and Community Health Workers were collected in hotspots, providing perspective on perceptions of why dengue, chikungunya and Zika hotspots exist, impediments to control, and social outcomes...
2017: PloS One
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