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Multiparametric mri and prostate

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https://www.readbyqxmd.com/read/28533806/second-salvage-high-dose-rate-brachytherapy-for-radiorecurrent-prostate-cancer
#1
Metha Maenhout, Marco van Vulpen, Marinus Moerland, Max Peters, Richard Meijer, Maurice van den Bosch, Paul Nguyen, Steven Frank, Jochem van der Voort van Zyp
PURPOSE: Salvage treatments for localized radiorecurrent prostate cancer can be performed safely when a focal and image guided approach is used. Due to the low toxicity, the opportunity exists to investigate a second salvage treatment when a second locally recurrent prostate cancer occurs. Here, we describe a second salvage treatment procedure of 4 patients. MATERIAL AND METHODS: Four patients with a pathologically proven second local recurrence were treated in an outpatient magnetic resonance imaging (MRI)-guided setting with a single fraction of 19 Gy focal high-dose-rate brachytherapy (HDR-BT)...
April 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28531902/evaluation-of-prostate-imaging-reporting-and-data-system-classification-in-the-prediction-of-tumor-aggressiveness-in-targeted-magnetic-resonance-imaging-ultrasound-fusion-biopsy
#2
Angelika Borkowetz, Ivan Platzek, Marieta Toma, Theresa Renner, Roman Herout, Martin Baunacke, Michael Laniado, Gustavo B Baretton, Michael Froehner, Stefan Zastrow, Manfred P Wirth
OBJECTIVES: The study aimed to evaluate the prediction of Prostate Imaging Reporting and Data System (PI-RADS) with respect to the prostate cancer (PCa) detection rate and tumor aggressiveness in magnetic resonance imaging (MRI)/ultrasound-fusion-biopsy (fusPbx) and in systematic biopsy (sysPbx). MATERIALS AND METHODS: Six hundred and twenty five patients undergoing multiparametric MRI were investigated. MRI findings were classified using PI-RADS v1 or v2. All patients underwent fusPbx combined with sysPbx (comPbx)...
May 23, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28513296/confirmatory-biopsy-of-men-under-active-surveillance-extended-versus-saturation-versus-multiparametric-magnetic-resonance-imaging-transrectal-ultrasound-fusion-prostate-biopsy
#3
Pietro Pepe, Sebastiano Cimino, Antonio Garufi, Giandomenico Priolo, Giorgio Ivan Russo, Raimondo Giardina, Giulio Reale, Michele Pennisi, Giuseppe Morgia
OBJECTIVE: The aim of this study was to evaluate the detection rate for clinically significant prostate cancer (PCa) after multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound (TRUS) fusion biopsy versus extended biopsy or saturation prostate biopsy (SPBx) in men enrolled on active surveillance (AS). MATERIALS AND METHODS: From May 2013 to January 2016, 100 men with very low-risk PCa were enrolled on AS. Eligible criteria were: life expectancy greater than 10 years, cT1c, prostate-specific antigen (PSA) below 10 ng/ml, PSA density less than 0...
May 17, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28511220/-significance-and-value-of-psma-ligands-in-prostate-cancer
#4
Claudia Gasch, Stefan Körber, Christophe Kremer, Matthias Eiber, Clemens Kratochwil, Uwe Haberkorn, Markus Hohenfellner, Boris Hadaschik, Frederik L Giesel
In recent years, PSMA-targeting PET tracers such as (68)Ga-PSMA-11 have shown promising results, thus contributing to a better management of prostate cancer patients. At the present time, (68)Ga-PSMA-11 is most frequently used for diagnostic evaluation in the setting of biochemical recurrence of prostate cancer. In this context, the (68)Ga-PSMA-11 PET/CT delivers superior detection rates compared to conventional imaging, especially for the detection of small, unsuspicious lesions or lesions in the presence of low PSA values...
April 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28506596/advances-in-medical-imaging-for-the-diagnosis-and-management-of-common-genitourinary-cancers
#5
REVIEW
Mohammad H Bagheri, Mark A Ahlman, Liza Lindenberg, Baris Turkbey, Jeffrey Lin, Ali Cahid Civelek, Ashkan A Malayeri, Piyush K Agarwal, Peter L Choyke, Les R Folio, Andrea B Apolo
Medical imaging of the 3 most common genitourinary (GU) cancers-prostate adenocarcinoma, renal cell carcinoma, and urothelial carcinoma of the bladder-has evolved significantly during the last decades. The most commonly used imaging modalities for the diagnosis, staging, and follow-up of GU cancers are computed tomography, magnetic resonance imaging (MRI), and positron emission tomography (PET). Multiplanar multidetector computed tomography and multiparametric MRI with diffusion-weighted imaging are the main imaging modalities for renal cell carcinoma and urothelial carcinoma, and although multiparametric MRI is rapidly becoming the main imaging tool in the evaluation of prostate adenocarcinoma, biopsy is still required for diagnosis...
May 12, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28503230/utility-of-preoperative-3-tesla-pelvic-phased-array-multiparametric-magnetic-resonance-imaging-in-prediction-of-extracapsular-extension-and-seminal-vesicle-invasion-of-prostate-cancer-and-its-impact-on-surgical-margin-status-experience-at-a-canadian-academic
#6
Taehyoung Lee, Jen Hoogenes, Ian Wright, Edward D Matsumoto, Bobby Shayegan
INTRODUCTION: To evaluate the utility of 3 Tesla (3T) pelvic phased-array (PPA) multiparametric magnetic resonance imaging (mpMRI) to predict extracapsular extension (ECE) and seminal vesicle invasion (SVI) and its subsequent effect on radical prostatectomy (RP) surgical margin status. METHODS: A retrospective evaluation was conducted of RP patients who underwent preoperative 3T PPA mpMRI (without endorectal coil) based on clinical probability of adverse pathological features...
May 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28502474/-role-of-prostate-mri-trus-fusion-biopsies-and-new-markers-in-the-diagnostic-strategy-of-prostate-cancer
#7
Raphaële Renard-Penna, Pierre Mozer, Luca Lunelli, Olivier Cussenot
Multiparametric MRI prostate (mp-MRI) is a powerful tool to locate lesions>0.5cm(3) (below this threshold tumor volume, prostate cancers are classified as "insignificant"). The detection rate of the mp-MRI for significant cancers of small volume (0.5-1cm(3)) with a Gleason score≥7 is>85 %. The prostate mp-MRI optimizes the management of cancers classified as low risk of progression by providing aggressive criteria for misclassified lesions, which require an active treatment and enhance the clinicopathological criteria of indolence for subclinical lesions, which can justify of surveillance...
May 11, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28501565/prostate-zonal-anatomy-correlates-with-the-detection-of-prostate-cancer-on-multiparametric-magnetic-resonance-imaging-ultrasound-fusion-targeted-biopsy-in-patients-with-a-solitary-pi-rads-v2-scored-lesion
#8
Jamil S Syed, Kevin A Nguyen, Cayce B Nawaf, Ansh M Bhagat, Steffen Huber, Angelique Levi, Peter Humphrey, Jeffrey C Weinreb, Peter G Schulam, Preston C Sprenkle
PURPOSE: To evaluate the positive predictive value (PPV) of the Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) assessment method in patients with a single suspicious finding on prostate multiparametric magnetic resonance imaging (mpMRI). PATIENTS AND METHODS: A total of 176 patients underwent MRI/ultrasound fusion-targeted prostate biopsy after the detection of a single suspicious finding on mpMRI. The PPV for cancer detection was determined based on PI-RADS v2 assessment score and location...
May 10, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28494579/multiparametric-prostate-mri-technical-conduct-standardized-report-and-clinical-use-a-narrative-review
#9
Matteo Manfredi, Fabrizio Mele, Diletta Garrou, Jochen Walz, Jurgen J Fütterer, Filippo Russo, Lorenzo Vassallo, Arnauld Villers, Mark Emberton, Massimo Valerio
Multiparametric prostate MRI (mp-MRI) is an emerging imaging modality for diagnosis, characterization, staging, and treatment planning of prostate cancer (PCa). The technique, results reporting, and its role in clinical practice have been the subject of significant development over the last decade. Although mp-MRI is not yet routinely used in the diagnostic pathway, almost all urological guidelines have emphasized the potential role of mp-MRI in several aspects of PCa management. Moreover, new MRI sequences and scanning techniques are currently under evaluation to improve the diagnostic accuracy of mp-MRI...
May 11, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28488844/mri-in-prostate-cancer-detection-and-management-a-systematic-review
#10
Fabio Monni, Paolo Fontanella, Angelica Grasso, Peter Wiklund, Yen-Chuan Ou, Marco Randazzo, Bernardo Rocco, Emanuele Montanari, Giampaolo Bianchi
INTRODUCTION: The aim of our work was to evaluate the role of multi-parametric MRI (mpMRI) in detection and management of prostate cancer (PC); specifically investigating the efficacy of mpMRI-based biopsy techniques in terms of diagnostic yield of significant prostate neoplasm and the improved management of patient who choose conservative treatments or active surveillance. EVIDENCE ACQUISITION: A systematic and critical analysis through Medline, Embase, Scopus and Web of Science databases was carried out in March 2016, following the PRISMA ("Preferred Reporting Items for Systematic Reviews and Meta-Analyses") statement...
May 8, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28485391/magnetic-resonance-imaging-targeted-transperineal-prostate-biopsy-a-local-anaesthetic-approach
#11
E J Bass, I A Donaldson, A Freeman, C Jameson, S Punwani, C Moore, M Arya, M Emberton, H U Ahmed
BACKGROUND: Despite high rates of disease misclassification and sepsis, the use of transrectal biopsy remains commonplace. Transperineal mapping biopsies mitigate these problems but carry increased cost and patient burden. Local anaesthetic, multiparametric magnetic resonance imaging (MRI)-targeted transperineal biopsy may offer an alternative. Here, we aim to determine the feasibility, tolerability and detection rates of clinically significant prostate cancer using a local anaesthetic, transperineal, MRI-targeted biopsy technique...
May 9, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28479202/opening-our-eyes-to-multiparametric-magnetic-resonance-imaging-before-prostate-biopsy
#12
EDITORIAL
Hashim U Ahmed
No abstract text is available yet for this article.
May 4, 2017: European Urology
https://www.readbyqxmd.com/read/28479189/mri-based-salvage-brachytherapy-moving-toward-a-focal-paradigm
#13
Marisa A Kollmeier, Michael Zelefsky, Sean McBride
Brachytherapy is an ideal treatment approach for radiorecurrent prostate cancer given the highly conformal treatment. Increasingly, multiparametric magnetic resonance imaging is being utilized to enhance our ability to assess intraprostatic tumor characteristics. This article aims to review the current literature on whole gland salvage brachytherapy for radiorecurrent prostate cancer as well as the methodology and progress towards a focal approach to salvage brachytherapy. Particular emphasis is placed on the potential role of multiparametric MRI in achieving optimal outcomes with focal salvage brachytherapy...
May 4, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28476529/is-suspicious-upstaging-on-multiparametric-magnetic-resonance-imaging-useful-in-improving-the-reliability-of-prostate-cancer-research-international-active-surveillance-prias-criteria-use-of-the-k-cap-registry
#14
Sagnjun Yoo, Jun Hyuk Hong, Seok-Soo Byun, Ji Youl Lee, Byung Ha Chung, Choung-Soo Kim
BACKGROUND AND OBJECTIVE: To evaluate the clinical effects of suspicious upstaging on multiparametric magnetic resonance imaging (mpMRI) for improving the quality of Prostate Cancer Research International Active Surveillance (PRIAS) criteria. MATERIAL AND METHODS: A total of 363 patients with low-risk prostate cancer (PCa) were selected from the K-CaP registry (the multicenter Korean PCa Database). Patients were divided into 2 groups according to the results of mpMRI (with or without suspicious upstaging)...
May 2, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28473595/intra-individual-comparison-of-18-f-psma-1007-pet-ct-multi-parametric-mri-and-radical-prostatectomy-specimen-in-patients-with-primary-prostate-cancer-a-retrospective-proof-of-concept-study
#15
Claudia Kesch, Maria Vinsensia, Jan P Radtke, Heinz P Schlemmer, Martina Heller, Elena Ellert, Tim Holland-Letz, Stefan Duensing, Nils Grabe, Ali Afshar-Oromieh, Kathrin Wieczorek, Martin Schäfer, Oliver C Neels, Jens Cardinale, Clemens Kratochwil, Markus Hohenfellner, Klaus Kopka, Uwe Haberkorn, Boris A Hadaschik, Frederik L Giesel
Background:(68)Ga-prostate-specific membrane antigen (PSMA)-11-positron-emission-tomography (PET)/ computer-tomography (CT) represents an advanced method for staging of primary prostate cancer (PCa) and diagnosis of recurrent or metastatic PCa. However, due to the narrow availability of (68)Ga the development of alternative tracers is of high interest. Objective: To examine the value of the new PET tracer (18)F-PSMA-1007 for staging of local disease by comparing it to multiparametric magnetic resonance imaging (mpMRI) and radical prostatectomy (RP) histopathology...
May 4, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28473218/predicting-extracapsular-involvement-in-prostate-cancer-through-the-tumor-contact-length-and-the-apparent-diffusion-coefficient
#16
M F Granja, C M Pedraza, D C Flórez, J A Romero, M A Palau, D A Aguirre
OBJECTIVE: To evaluate the diagnostic performance of the length of the tumor contact with the capsule (LTC) and the apparent diffusion coefficient (ADC) map in the prediction of microscopic extracapsular extension in patients with prostate cancer who are candidates for radical prostatectomy. MATERIAL AND METHODS: We used receiver operating curves to retrospectively study the diagnostic performance of the ADC map and the LTC as predictors of microscopic extracapsular extension in 92 patients with prostate cancer and moderate to high risk who were examined between May 2011 and December 2013...
May 1, 2017: Radiología
https://www.readbyqxmd.com/read/28473080/acr-appropriateness-criteria-%C3%A2-prostate-cancer-pretreatment-detection-surveillance-and%C3%A2-staging
#17
Fergus V Coakley, Aytekin Oto, Lauren F Alexander, Brian C Allen, Brian J Davis, Adam T Froemming, Pat F Fulgham, Keyanoosh Hosseinzadeh, Christopher Porter, V Anik Sahni, David M Schuster, Timothy N Showalter, Aradhana M Venkatesan, Sadhna Verma, Carolyn L Wang, Erick M Remer, Steven C Eberhardt
Despite the frequent statement that "most men die with prostate cancer, not of it," the reality is that prostate cancer is second only to lung cancer as a cause of death from malignancy in American men. The primary goal during baseline evaluation of prostate cancer is disease characterization, that is, establishing disease presence, extent (local and distant), and aggressiveness. Prostate cancer is usually diagnosed after the finding of a suspicious serum prostate-specific antigen level or digital rectal examination...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28469301/multiparametric-magnetic-resonance-imaging-transrectal-ultrasound-fusion-prostate-biopsy-a-prospective-single-centre-study
#18
Somendra Bansal, Narmada P Gupta, Rajiv Yadav, Rakesh Khera, Kulbir Ahlawat, Dheeraj Gautam, Rajesh Ahlawat, Gagan Gautam
INTRODUCTION: Transrectal rectal ultrasound (TRUS)-guided systematic biopsy is the gold standard for diagnosis of prostate cancer. However, systematic biopsy has high false-negative rate and often misses anteriorly located tumors. Magnetic resonance imaging (MRI)-TRUS fusion biopsy can potentially improve cancer detection by better visualization and targeting of cancer focus. We evaluated the role of fusion biopsy in detection of prostate cancer and the association of prostate imaging reporting and data system (PI-RADS) score for predicting cancer risk and its aggression...
April 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28463931/multiparametric-magnetic-resonance-imaging-of-the-prostate-repeatability-of-volume-and-apparent-diffusion-coefficient-quantification
#19
Andriy Fedorov, Mark G Vangel, Clare M Tempany, Fiona M Fennessy
OBJECTIVES: The aim of this study was to evaluate the repeatability of a region of interest (ROI) volume and mean apparent diffusion coefficient (ADC) in standard-of-care 3 T multiparametric magnetic resonance imaging (mpMRI) of the prostate obtained with the use of endorectal coil. MATERIALS AND METHODS: This prospective study was Health Insurance Portability and Accountability Act compliant, with institutional review board approval and written informed consent...
May 1, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28451763/evaluating-the-performance-of-pi-rads-v2-in-the-non-academic-setting
#20
Eric J Jordan, Charles Fiske, Ronald J Zagoria, Antonio C Westphalen
PURPOSE: To evaluate the utility of PI-RADS v2 to diagnose clinically significant prostate cancer (CS-PCa) with magnetic resonance ultrasound (MR/US) fusion-guided prostate biopsies in the non-academic setting. MATERIALS/METHODS: Retrospective analysis of men whom underwent prostate multiparametric MRI and subsequent MR/US fusion biopsies at a single non-academic center from 11/2014 to 3/2016. Prostate MRIs were performed on a 3-Tesla scanner with a surface body coil...
April 27, 2017: Abdominal Radiology
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