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Multiparametric mri and prostate

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https://www.readbyqxmd.com/read/28424829/-mri-of-the-prostate
#1
D Nörenberg, O Solyanik, B Schlenker, G Magistro, B Ertl-Wagner, D A Clevert, C Stief, M F Reiser, M D'Anastasi
New clinical and technological advances in the field of magnetic resonance imaging (MRI) and targeted image-guided biopsy techniques have significantly improved the detection, localization and staging as well as active surveillance of prostate cancer in recent years. Multiparametric MRI (mpMRI) is currently the main imaging technique for the detection, characterization and diagnostics of metastasizing prostate cancer and is of high diagnostic importance for local staging within the framework of the detection of prostate cancer...
April 19, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28401579/mri-assessment-of-tissue-effects-after-180-w-xps-greenlight-laser-vaporization-of-the-prostate
#2
Romain Huet, Romain Mathieu, Tanguy Rohou, Benoit Peyronnet, Andrea Manunta, Gregory Verhoest, Karim Bensalah, Sebastien Vincendeau
BACKGROUND AND OBJECTIVE: Photoselective vaporization of the prostate (PVP) is an alternative to transurethral resection of the prostate (TURP) in the surgical management of Benign Prostate Obtruction (BPO), with a better hemostatic effect due to a coagulation depth of several millimeters. The objective of this study was to prospectively assess the tissue effects of PVP by Magnetic Resonance Imaging (MRI). MATERIALS AND METHODS: From December to February 2014, ten patients were included in a prospective study and underwent PVP performed by a single surgeon with the Greenlight™ laser 180-W XPS...
April 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28400169/combined-clinical-parameters-and-multiparametric-magnetic-resonance-imaging-for-advanced-risk-modeling-of-prostate-cancer-patient-tailored-risk-stratification-can-reduce-unnecessary-biopsies
#3
Jan Philipp Radtke, Manuel Wiesenfarth, Claudia Kesch, Martin T Freitag, Celine D Alt, Kamil Celik, Florian Distler, Wilfried Roth, Kathrin Wieczorek, Christian Stock, Stefan Duensing, Matthias C Roethke, Dogu Teber, Heinz-Peter Schlemmer, Markus Hohenfellner, David Bonekamp, Boris A Hadaschik
BACKGROUND: Multiparametric magnetic resonance imaging (mpMRI) is gaining widespread acceptance in prostate cancer (PC) diagnosis and improves significant PC (sPC; Gleason score≥3+4) detection. Decision making based on European Randomised Study of Screening for PC (ERSPC) risk-calculator (RC) parameters may overcome prostate-specific antigen (PSA) limitations. OBJECTIVE: We added pre-biopsy mpMRI to ERSPC-RC parameters and developed risk models (RMs) to predict individual sPC risk for biopsy-naïve men and men after previous biopsy...
April 8, 2017: European Urology
https://www.readbyqxmd.com/read/28393492/reliability-of-negative-multiparametric-mri-of-the-prostate-can-we-avoid-the-biopsy-not-yet
#4
EDITORIAL
Mark Frydenberg
No abstract text is available yet for this article.
May 2017: BJU International
https://www.readbyqxmd.com/read/28391284/gleason-score-within-prostate-abnormal-areas-defined-by-multiparametric-magnetic-resonance-imaging-did-not-vary-according-to-the-pirads-score
#5
Hakim Slaoui, Yann Neuzillet, Tarek Ghoneim, Mathieu Rouanne, Abdelali Abdou, Pierre Marie Lugagne-Delpon, Antoine Scherrer, Camelia Radulescu, Christian Delancourt, Vincent Molinié, Thierry Lebret
BACKGROUND: We aim to correlate multiparametric magnetic resonance imaging (mpMRI) of the prostate reporting (Prostate Imaging Reporting and Data System [PI-RADS] version 2) with the Gleason score into both radical prostatectomy (RP) specimen and MRI fusion-targeted biopsies (FTB). METHODS: mpMRI of 74 patients who underwent an RP after FTB were retrospectively reviewed. The Gleason score distribution was compared according to the PI-RADS score using the Kruskal-Wallis test...
April 8, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28386721/multiparametric-magnetic-resonance-imaging-of-the-prostate-with-computer-aided-detection-experienced-observer-performance-study
#6
Valentina Giannini, Simone Mazzetti, Enrico Armando, Silvia Carabalona, Filippo Russo, Alessandro Giacobbe, Giovanni Muto, Daniele Regge
OBJECTIVES: To compare the performance of experienced readers in detecting prostate cancer (PCa) using likelihood maps generated by a CAD system with that of unassisted interpretation of multiparametric magnetic resonance imaging (mp-MRI). METHODS: Three experienced radiologists reviewed mp-MRI prostate cases twice. First, readers observed CAD marks on a likelihood map and classified as positive those suspicious for cancer. After 6 weeks, radiologists interpreted mp-MRI examinations unassisted, using their favourite protocol...
April 6, 2017: European Radiology
https://www.readbyqxmd.com/read/28385253/prostate-cancer-state-of-the-art-imaging-and-focal-treatment
#7
REVIEW
D A Woodrum, A Kawashima, K R Gorny, L A Mynderse
In 2016, it is estimated 180,890 men are newly diagnosed with prostate cancer and 3,306,760 men live with prostate cancer in the United States. The introduction of multiparametric (mp) magnetic resonance imaging (MRI) of the prostate, standardised interpretation guidelines such as Prostate Imaging Reporting and Data System (PI-RADS version 2), and MRI-based targeted biopsy has improved detection of clinically significant prostate cancer. Accurate risk stratification (Gleason grade/score and tumour stage) using imaging and image-guided targeted biopsy has become critical for the management of patients with prostate cancer...
April 3, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28381220/the-prostate-cancer-detection-rates-of-ceus-targeted-versus-mri-targeted-versus-systematic-trus-guided-biopsies-in-biopsy-na%C3%A3-ve-men-a-prospective-comparative-clinical-trial-using-the-same-patients
#8
A W Postema, M J V Scheltema, C K Mannaerts, R J G Van Sloun, T Idzenga, M Mischi, M R E Engelbrecht, J J M C H De la Rosette, H Wijkstra
BACKGROUND: The current standard for Prostate Cancer (PCa) detection in biopsy-naïve men consists of 10-12 systematic biopsies under ultrasound guidance. This approach leads to underdiagnosis and undergrading of significant PCa while insignificant PCa may be overdiagnosed. The recent developments in MRI and Contrast Enhanced Ultrasound (CEUS) imaging have sparked an increasing interest in PCa imaging with the ultimate goal of replacing these "blind" systematic biopsies with reliable imaging-based targeted biopsies...
April 5, 2017: BMC Urology
https://www.readbyqxmd.com/read/28379863/improved-magnetic-resonance-imaging-pathology-correlation-with-imaging-derived-3d-printed-patient-specific-whole-mount-molds-of-the-prostate
#9
Daniel N Costa, Yonatan Chatzinoff, Niccolo M Passoni, Payal Kapur, Claus G Roehrborn, Yin Xi, Neil M Rofsky, Jose Torrealba, Franto Francis, Cecil Futch, Phyllis Hagens, Hollis Notgrass, Susana Otero-Muinelo, Ivan Pedrosa, Rajiv Chopra
OBJECTIVES: The aim of this study was to compare the anatomical registration of preoperative magnetic resonance imaging (MRI) and prostate whole-mount obtained with 3D-printed, patient-specific, MRI-derived molds (PSM) versus conventional whole-mount sectioning (WMS). MATERIALS AND METHODS: Based on an a priori power analysis, this institutional review board-approved study prospectively included 50 consecutive men who underwent 3 T multiparametric prostate MRI followed by radical prostatectomy...
April 4, 2017: Investigative Radiology
https://www.readbyqxmd.com/read/28373135/the-value-of-psa-density-in-combination-with-pi-rads-for-the-accuracy-of-prostate-cancer-prediction
#10
Florian A Distler, Jan P Radtke, David Bonekamp, Claudia Kesch, Heinz-Peter Schlemmer, Kathrin Wieczorek, Marietta Kirchner, Sascha Pahernik, Markus Hohenfellner, Boris A Hadaschik
PURPOSE: Multiparametric MRI (mpMRI) has an emerging role in prostate cancer (PC) diagnostics. In addition, clinical information are reliable predictors for significant PC (sPC). We analyzed if the negative predictive value (NPV) of mpMRI to rule out sPC could be improved by using clinical factors, especially prostate specific antigen (PSA)-density. METHODS: 1040 consecutive men with suspicion of PC underwent mpMRI first, followed by transperineal systematic and MRI/TRUS-fusion-guided biopsy...
March 31, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28351193/measurement-of-serum-isoform-2-propsa-derivatives-shows-superior-accuracy-to-magnetic-resonance-imaging-in-the-diagnosis-of-prostate-cancer-in-patients-with-a-total-prostate-specific-antigen-level-of-2-10%C3%A2-ng-ml
#11
Kazuhiro Furuya, Takashi Kawahara, Masaki Narahara, Takashi Tokita, Sachi Fukui, Masashi Imano, Taku Mitome, Yusuke Ito, Koji Izumi, Kimito Osaka, Yumiko Yokomizo, Narihiko Hayashi, Hisashi Hasumi, Shintaro Nawata, Tsuyoshi Kawano, Masahiro Yao, Hiroji Uemura
OBJECTIVE: More accurate diagnostic procedures for prostate cancer are needed to avoid unnecessary biopsy due to the low specificity of prostate-specific antigen (PSA). Recent studies showed that the percentage of serum isoform [-2]proPSA (p2PSA) to free PSA (%p2PSA), the Prostate Health Index (PHI) and magnetic resonance imaging (MRI) were more accurate than PSA. The aim of this study was to test the accuracy of %p2PSA, PHI and MRI in discriminating patients with and without prostate cancer...
March 29, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28350785/the-picture-study-diagnostic-accuracy-of-multiparametric-mri-in-men-requiring-a-repeat-prostate-biopsy
#12
Lucy A M Simmons, Abi Kanthabalan, Manit Arya, Tim Briggs, Dean Barratt, Susan C Charman, Alex Freeman, James Gelister, David Hawkes, Yipeng Hu, Charles Jameson, Neil McCartan, Caroline M Moore, Shonit Punwani, Navin Ramachandran, Jan van der Meulen, Mark Emberton, Hashim U Ahmed
BACKGROUND: Transrectal prostate biopsy has limited diagnostic accuracy. Prostate Imaging Compared to Transperineal Ultrasound-guided biopsy for significant prostate cancer Risk Evaluation (PICTURE) was a paired-cohort confirmatory study designed to assess diagnostic accuracy of multiparametric magnetic resonance imaging (mpMRI) in men requiring a repeat biopsy. METHODS: All underwent 3 T mpMRI and transperineal template prostate mapping biopsies (TTPM biopsies)...
March 28, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28349978/patient-selection-for-prostate-focal-therapy-in-the-era-of-active-surveillance-an-international-delphi-consensus-project
#13
K J Tay, M J Scheltema, H U Ahmed, E Barret, J A Coleman, J Dominguez-Escrig, S Ghai, J Huang, J S Jones, L H Klotz, C N Robertson, R Sanchez-Salas, S Scionti, A Sivaraman, J de la Rosette, T J Polascik
BACKGROUND: Whole-gland extirpation or irradiation is considered the gold standard for curative oncological treatment for localized prostate cancer, but is often associated with sexual and urinary impairment that adversely affects quality of life. This has led to increased interest in developing therapies with effective cancer control but less morbidity. We aimed to provide details of physician consensus on patient selection for prostate focal therapy (FT) in the era of contemporary prostate cancer management...
March 28, 2017: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/28344811/the-role-of-imaging-in-the-diagnosis-of-primary-prostate-cancer
#14
Hugh Harvey, Nandita M deSouza
Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state following injection of weakly paramagnetic agents such as gadolinium. Together these parameters are referred to as multiparametric (mp)MRI and are used for detecting and guiding biopsy and staging prostate cancer. Although sensitivity of mpMRI is <75% for disease detection, specificity is >90% and a standardised reporting system together with MR-guided targeted biopsy is the optimal diagnostic pathway...
December 2016: Journal of Clinical Urology
https://www.readbyqxmd.com/read/28336078/what-is-the-negative-predictive-value-of-multiparametric-magnetic-resonance-imaging-in-excluding-prostate-cancer-at-biopsy-a-systematic-review-and-meta-analysis-from-the-european-association-of-urology-prostate-cancer-guidelines-panel
#15
REVIEW
Paul C Moldovan, Thomas Van den Broeck, Richard Sylvester, Lorenzo Marconi, Joaquim Bellmunt, Roderick C N van den Bergh, Michel Bolla, Erik Briers, Marcus G Cumberbatch, Nicola Fossati, Tobias Gross, Ann M Henry, Steven Joniau, Theo H van der Kwast, Vsevolod B Matveev, Henk G van der Poel, Maria De Santis, Ivo G Schoots, Thomas Wiegel, Cathy Yuhong Yuan, Philip Cornford, Nicolas Mottet, Thomas B Lam, Olivier Rouvière
CONTEXT: It remains unclear whether patients with a suspicion of prostate cancer (PCa) and negative multiparametric magnetic resonance imaging (mpMRI) can safely obviate prostate biopsy. OBJECTIVE: To systematically review the literature assessing the negative predictive value (NPV) of mpMRI in patients with a suspicion of PCa. EVIDENCE ACQUISITION: The Embase, Medline, and Cochrane databases were searched up to February 2016. Studies reporting prebiopsy mpMRI results using transrectal or transperineal biopsy as a reference standard were included...
March 20, 2017: European Urology
https://www.readbyqxmd.com/read/28333020/-18-f-choline-positron-emission-tomography-computed-tomography-and-multiparametric-magnetic-resonance-imaging-for-the-detection-of-early-local-recurrence-of-prostate-cancer-initially-treated-by-radiation-therapy-comparison-with-systematic-3-dimensional-transperineal
#16
Salim Kanoun, Paul Walker, Jean-Marc Vrigneaud, Edouard Depardon, Vincent Barbier, Olivier Humbert, Morgan Moulin, Gilles Créhange, Luc Cormier, Romaric Loffroy, François Brunotte, Alexandre Cochet
PURPOSE: To compare the diagnostic performance of (18)F-fluorocholine positron emission tomography/computed tomography (FCH-PET/CT), multiparametric prostate magnetic resonance imaging (mpMRI), and a combination of both techniques for the detection of local recurrence of prostate cancer initially treated by radiation therapy. METHODS AND MATERIALS: This was a retrospective, single-institution study of 32 patients with suspected prostate cancer recurrence who underwent both FCH-PET/CT and 3T mpMRI within 3 months of one another for the detection of recurrence...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28333017/effect-of-prostate-magnetic-resonance-imaging-ultrasound-fusion-guided-biopsy-on-radiation-treatment-recommendations
#17
Aaron Reed, Luca F Valle, Uma Shankavaram, Andra Krauze, Aradhana Kaushal, Erica Schott, Theresa Cooley-Zgela, Bradford Wood, Peter Pinto, Peter Choyke, Baris Turkbey, Deborah E Citrin
PURPOSE: Targeted magnetic resonance imaging (MRI)/ultrasound fusion prostate biopsy (MRI-Bx) has recently been compared with the standard of care extended sextant ultrasound-guided prostate biopsy (SOC-Bx), with the former associated with an increased rate of detection of clinically significant prostate cancer. The present study sought to determine the influence of MRI-Bx on radiation therapy and androgen deprivation therapy (ADT) recommendations. METHODS AND MATERIALS: All patients who had received radiation treatment and had undergone SOC-Bx and MRI-Bx at our institution were included...
April 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28330587/comparison-of-semi-automated-and-manual-methods-to-measure-the-volume-of-prostate-cancer-on-magnetic-resonance-imaging
#18
L Marin, M Ezziane, E Comperat, P Mozer, G Cancel-Tassin, J-F Coté, D Racoceanu, F Boudghene, O Lucidarme, O Cussenot, R Renard Penna
PURPOSE: The purpose of this study was to determine the accuracy of manual semi-automated and volumetric measurements to assess prostate cancer volume on multiparametric magnetic resonance imaging (MP-MRI) using whole-mount histopathology for validation. MATERIALS AND METHODS: We evaluated 30 consecutive men (median age, 65.7 years; interquartile range [IQR], 61.5-70.9 years) with a median prostatic specific antigen of 8.5ng/dL (IQR, 5.5-10.5ng/dL), who underwent MP-MRI before radical prostatectomy...
March 15, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28322902/negative-multi-parametric-mri-of-the-prostate-predicts-absence-of-clinically-significant-prostate-cancer-on-12-core-template-prostate-biopsy
#19
Amanda J Lu, Jamil S Syed, Kevin A Nguyen, Cayce B Nawaf, James Rosoff, Michael Spektor, Angelique Levi, Peter A Humphrey, Jeffrey C Weinreb, Peter G Schulam, Preston C Sprenkle
OBJECTIVE: To determine the negative predictive value of multiparametric-MRI (mpMRI), we evaluated the frequency of prostate cancer detection by 12-core template mapping biopsy in men whose mpMRI showed no suspicious regions. METHODS: 670 patients underwent mpMRI followed by transrectal ultrasound-(TRUS) guided systematic prostate biopsy from December 2012 to June 2016. Of this cohort, 100 patients had a negative mpMRI. mpMRI imaging sequences included T2-weighted, diffusion-weighted imaging, and dynamic contrast enhancement sequences...
March 16, 2017: Urology
https://www.readbyqxmd.com/read/28314291/biparametric-versus-multiparametric-mri-with-non-endorectal-coil-at-3t-in-the-detection-and-localization-of-prostate-cancer
#20
Michele Scialpi, Enrico Prosperi, Alfredo D'Andrea, Eugenio Martorana, Corrado Malaspina, Barbara Palumbo, Agostino Orlandi, Giuseppe Falcone, Michele Milizia, Luigi Mearini, Maria Cristina Aisa, Pietro Scialpi, Carlo DE Domincis, Giampaolo Bianchi, Angelo Sidoni
AIM: To assess the sensitivity of biparametric magnetic resonance imaging (bpMRI) with non-endorectal coil in the detection and localization of index (dominant) and non-index lesions in patients suspected of having prostate cancer. PATIENTS AND METHODS: We carried-out a retrospective analysis of multiparametric MRI (mpMRI) of 41 patients who underwent radical prostatectomy. Results of MRI for detection and localization of index and non-index lesions were correlated with those of histology...
March 2017: Anticancer Research
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