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https://www.readbyqxmd.com/read/27898980/feasibility-of-macular-integrity-assessment-maia-microperimetry-in-children-sensitivity-reliability-and-fixation-stability-in-healthy-observers
#1
Pete R Jones, Narmella Yasoubi, Marko Nardini, Gary S Rubin
Purpose: To assess the feasibility of macular integrity assessment (MAIA) microperimetry (MP) in children. Also to establish representative outcome measures (differential light sensitivity, fixation stability, test-retest reliability) for children without visual impairment. Methods: Thirty-three adults and 33 children (9-12 years) were asked to perform three monocular MAIA examinations within a single session (dominant eye only). Results: Children exhibited poorer test-retest reliability than adults for measures of both mean sensitivity (95% coefficient of repeatability [CoR95] = 2...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27895939/malaria-moderate-to-severe-anaemia-and-malarial-anaemia-in-children-at-presentation-to-hospital-in-the-mount-cameroon-area-a-cross-sectional-study
#2
Irene Ule Ngole Sumbele, Sharon Odmia Sama, Helen Kuokuo Kimbi, Germain Sotoing Taiwe
Background. Malaria remains a major killer of children in Sub-Saharan Africa, while anaemia is a public health problem with significant morbidity and mortality. Examining the factors associated with moderate to severe anaemia (MdSA) and malarial anaemia as well as the haematological characteristics is essential. Methodology. Children (1-14 years) at presentation at the Regional Hospital Annex-Buea were examined clinically and blood samples were collected for malaria parasite detection and full blood count evaluation...
2016: Anemia
https://www.readbyqxmd.com/read/27856090/cystatin-c-and-cardiac-measures-in-children-and%C3%A2-adolescents%C3%A2-with-ckd
#3
Tammy M Brady, Kelly Townsend, Michael F Schneider, Christopher Cox, Thomas Kimball, Peace Madueme, Bradley Warady, Susan Furth, Mark Mitsnefes
BACKGROUND: Cardiovascular disease (CVD) is highly prevalent among children with chronic kidney disease (CKD). Cystatin C is an established marker of kidney function and an emerging biomarker for CVD events. We quantified the relationship between cystatin C level and cardiac structure and function over time among children with CKD and assessed whether cystatin C level and diastolic function retained an association after accounting for kidney function. STUDY DESIGN: Prospective cohort study...
November 14, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27846417/threat-interpretation-and-parental-influences-for-children-with-asthma-and-anxiety
#4
Gemma Sicouri, Louise Sharpe, Jennifer L Hudson, Jo Dudeney, Adam Jaffe, Hiran Selvadurai, Sarah Lorimer, Caroline Hunt
Anxiety disorders are highly prevalent in children with asthma yet very little is known about the cognitive and parent factors that may underpin this relationship. The present study investigated interpretation biases in children with asthma and anxiety and their parents, and whether parent-child discussions influenced children's interpretations. Eighty-nine parent-child dyads were included across four groups: children with asthma and anxiety, children with anxiety only, children with asthma only and healthy children (aged between 8 and 13 years old)...
November 10, 2016: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/27788403/preschool-children-use-space-rather-than-counting-to-infer-the-numerical-magnitude-of-digits-evidence-for-a-spatial-mapping-principle
#5
Francesco Sella, Ilaria Berteletti, Daniela Lucangeli, Marco Zorzi
A milestone in numerical development is the acquisition of counting principles which allow children to exactly determine the numerosity of a given set. Moreover, a canonical left-to-right spatial layout for representing numbers also emerges during preschool. These foundational aspects of numerical competence have been extensively studied, but there is sparse knowledge about the interplay between the acquisition of the cardinality principle and spatial mapping of numbers in early numerical development. The present study investigated how these skills concurrently develop before formal schooling...
October 24, 2016: Cognition
https://www.readbyqxmd.com/read/27749630/association-of-delay-in-appendectomy-with-perforation-in-children-with-appendicitis
#6
James A Meltzer, Sergey Kunkov, Jennifer H Chao, Ee Tein Tay, Jerry P George, David Borukhov, Stephen Alerhand, Prince A Harrison, Jeffrey Hom, Ellen F Crain
OBJECTIVE: The aim of this study was to assess whether increased time from emergency department (ED) triage to appendectomy is associated with a greater risk of children developing appendiceal perforation. METHODS: We performed a multicenter retrospective cohort study of children younger than 18 years hospitalized with appendicitis. To avoid enrolling patients who had perforated prior to ED arrival, we included only children who had a computed tomography (CT) scan demonstrating nonperforated appendicitis...
September 30, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27738597/socioeconomic-impacts-of-gluten-free-diet-among-saudi-children-with-celiac-disease
#7
Ahmed Sarkhy, Mohammad I El Mouzan, Elshazaly Saeed, Aziz Alanazi, Sharifa Alghamdi, Shirin Anil, Asaad Assiri
PURPOSE: To determine the socio-economic impact of gluten free diet (GFD) on Saudi children and their families. METHODS: A cross-sectional study was conducted in which an online questionnaire was sent to all families registered in the Saudi celiac patients support group. We included only children (age 18 years of age and younger) with biopsy-confirmed celiac disease (CD). RESULTS: A total of 113 children were included in the final analysis, the median age was 9...
September 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/27736034/sensitivity-of-newly-defined-impulse-oscillometry-indices-in-preschool-children
#8
Hanna Knihtilä, Anne Kotaniemi-Syrjänen, Anna S Pelkonen, Satu Kalliola, Mika J Mäkelä, L Pekka Malmberg
INTRODUCTION: Early origins of chronic obstructive pulmonary disease have been recognized. Impulse oscillometry (IOS) is suitable for assessment of lung function also in preschool children, and some novel indices have been connected to assessment of small airway function. However, limited data exist on the sensitivity of these new indices to detect lung function deficits in young symptomatic children. METHODS: IOS measurements of 103 healthy preschool children were evaluated to establish reference equations for the difference between respiratory resistance at 5 and 20 Hz (R5-20), the relative difference of R5-20 (R5-20%), and area under the reactance curve (AX)...
October 13, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27726123/psychological-therapies-for-children-and-adolescents-exposed-to-trauma
#9
REVIEW
Donna Gillies, Licia Maiocchi, Abhishta P Bhandari, Fiona Taylor, Carl Gray, Louise O'Brien
BACKGROUND: Children and adolescents who have experienced trauma are at high risk of developing post-traumatic stress disorder (PTSD) and other negative emotional, behavioural and mental health outcomes, all of which are associated with high personal and health costs. A wide range of psychological treatments are used to prevent negative outcomes associated with trauma in children and adolescents. OBJECTIVES: To assess the effects of psychological therapies in preventing PTSD and associated negative emotional, behavioural and mental health outcomes in children and adolescents who have undergone a traumatic event...
October 11, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27676842/safety-and-effectiveness-of-early-intramuscular-botulinum-toxin-injections-to-prevent-shoulder-deformity-in-babies-with-obstetrical-brachial-plexus-palsy-presentation-of-a-multicentre-randomised-double-blind-placebo-controlled-trial
#10
Christelle Pons, Dinomais Mickael, Franck Fitoussi, Marie-Charlotte D'Anjou, Mélanie Porte, Emilie Rumilly, Nathaly Quintero, Philippe Violas, Sylvain Brochard
OBJECTIVE: In children with obstetrical brachial plexus palsy (OBPP), shoulder musculoskeletal deformity is the main cause of morbidity, with a loss of range of shoulder motion, pain and a reduction in social participation. Some uncontrolled studies show that early injections of botulinum toxin (BTI) in the internal shoulder rotator muscles (which cause the deformity) are one of the most promising treatments for the prevention of bony deformity. The main objective of this study will be the evaluation of the effectiveness of BTI in the internal shoulder rotator muscles at the age of 6 months in preventing an increase in posterior subluxation of the glenohumeral joint in babies with OBPP (evaluated at the ages of 5 and 12 months), compared with a placebo...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27592045/a-systematic-review-and-meta-analysis-of-outcomes-of-transcatheter-stent-implantation-for-the-primary-treatment-of-native-coarctation
#11
Linqi Yang, Xiuzhen Chua, Dimple D Rajgor, Bee Choo Tai, Swee Chye Quek
BACKGROUND/OBJECTIVES: The treatment of native coarctation of aorta (CoA) has evolved since surgery performed in 1944, followed by transcatheter balloon angioplasty and recently, widely adopted stent implantation. Despite good results demonstrated with stent implantation, a systematic review and meta-analysis (SRMA) looking at the efficacy and safety of the intervention, particularly in younger population is yet to be done. We aimed to obtain pooled estimates of the success and complication rates after transcatheter stent implantation in the treatment of native CoA based on SRMA...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27589674/congenital-heart-disease-in-lao-people-s-democratic-republic-2-years-experience-of-the-only-children-s-hospital
#12
In-Chang Hwang, Malouny Sisavanh, Somxay Billamay, Sommanikhone Phangmanixay, Bounleua Oudavong, Jeehoon Kang, Bo Sang Kwon, Gi Beom Kim, Eun Jung Bae, Chung Il Noh, Jung Yun Choi
BACKGROUND: Management of congenital heart disease (CHD) in developing countries is challenging because of limited access to healthcare facilities and socioeconomic limitations. We aimed to describe the recent experience with CHD at Children's Hospital of Lao People's Democratic Republic (PDR), the only pediatric referral hospital in the nation. METHODS: From July 2013 to November 2015, we performed 1,009 echocardiograms of 797 individuals who visited Children's Hospital and identified 213 CHD patients...
September 2, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27565788/2016-updated-mascc-esmo-consensus-recommendations-prevention-of-acute-chemotherapy-induced-nausea-and-vomiting-in-children
#13
L Lee Dupuis, Lillian Sung, Alexander Molassiotis, Andrea D Orsey, Wim Tissing, Marianne van de Wetering
PURPOSE: To update the 2009 recommendations for the prevention of acute chemotherapy-induced emesis in children. METHODS: We updated the original systematic literature search. Randomized studies were included in the evidence to support this guideline if they were primary studies fully published in full text in English or French; included only children less than 18 years old or, for mixed studies of adults and children, reported the pediatric results separately or the median or mean age was no more than 13 years; evaluated acute chemotherapy-induced nausea and vomiting (CINV) prophylaxis; provided sufficient information to permit determination of the emetogenicity of the antineoplastic therapy administered or the study investigators stated the emetogenicity of the chemotherapy administered; included an implicit or explicit definition of complete acute CINV response; described the antiemetic regimen in full; and reported the complete acute CINV response rate as a proportion...
January 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/27553256/-vaccination-coverage-and-socioeconomic-determinants-of-bcg-vaccination-in-children-before-3-months-results-of-the-elfe-cohort-study-2011
#14
J-P Guthmann, M Ragot, M Ben Boutieb, C Bois, M-N Dufourg, D Lévy-Bruhl
BACKGROUND: In 2007, French authorities changed mandatory BCG vaccination for all children into a strong recommendation to vaccinate only children considered at high risk of tuberculosis. Vaccination coverage (VC) data are insufficient in France. We estimated VC at approximately two months of age and identified socioeconomic factors associated with BCG vaccination. METHODS: The Elfe study (Étude Longitudinale Française depuis l'Enfance) included a random sample of about 18 000 children born in 2011 selected at birth from 320 maternity wards from mainland France...
September 2016: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/27552298/give-as-i-give-adult-influence-on-children-s-giving-in-two-cultures
#15
Peter R Blake, John Corbit, Tara C Callaghan, Felix Warneken
Adult influence on children's altruistic behavior may differ between cultural communities. We used an experimental approach to assess the influence of adult models on children's altruistic giving in a city in the United States and rural villages in India. Children between 3 and 8 years of age were tested with their parents in the United States (n=163) and India (n=154). Parents modeled either a generous or stingy donation; children then performed a similar task in private. Children in both communities were influenced by the stingy model, but only children in India increased their giving after viewing a generous model...
December 2016: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/27549305/gay-male-only-children-evidence-for-low-birth-weight-and-high-maternal-miscarriage-rates
#16
Malvina N Skorska, Ray Blanchard, Doug P VanderLaan, Kenneth J Zucker, Anthony F Bogaert
Recent findings suggest that there may be a maternal immune response underpinning the etiology of sexual orientation of gay male only-children. This maternal immune response appears to be distinct from that which is purported to explain the classic fraternal birth order effect found in studies of male sexual orientation. We tested two predictions related to the hypothesized maternal immune response in mothers of gay male only-children: (1) elevated fetal loss among mothers who have had gay male only-children and (2) lower birth weight in gay male only-children...
August 22, 2016: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/27537430/down-s-syndrome-is-a-risk-factor-for-severe-lower-respiratory-tract-infection-due-to-respiratory-syncytial-virus
#17
Constanza Galleguillos, Bárbara Galleguillos, Guillermo Larios, Gonzalo Menchaca, Louis Bont, Jose A Castro-Rodriguez
AIM: Previous studies have suggested that Down's syndrome is an independent risk factor for severe respiratory infection due to respiratory syncytial virus (RSV). We compared the clinical characteristics of children with and without Down's syndrome hospitalised due to RSV. METHODS: This retrospective cohort study compared data from hospitalisations due to RSV lower respiratory tract infections (LRTI) in children under 14 years of age with (n = 58) and without (n = 58) Down's syndrome...
November 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27533314/renal-function-recovery-after-nephrectomy-or-nephron-sparing-surgery-in-children-with-unilateral-renal-tumor
#18
Denis A Cozzi, Silvia Ceccanti, Francesco Cozzi
Introduction Children with unilateral renal tumor (URT) and preoperative renal dysfunction (PRD) may benefit from nephron-sparing surgery (NSS). To test this hypothesis, we studied the outcome of baseline renal function after nephrectomy or NSS among children with URT. Materials and Methods Retrospective records review of children with URT who underwent nephrectomy (25 children) or NSS (11 children) at our institution. We analyzed the estimated glomerular filtration rate (eGFR) changes over time among patients, stratified by both preoperative renal function (with or without PRD) and surgical extent (NSS vs...
August 17, 2016: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27491773/parental-migration-and-smoking-behavior-of-left-behind-children-evidence-from-a-survey-in-rural-anhui-china
#19
Tingting Yang, Cuicui Li, Chengchao Zhou, Shan Jiang, Jie Chu, Alexis Medina, Scott Rozelle
BACKGROUND: Parental migration is most an important factor affecting children's behaviors. Few studies have addressed the association between parental migration and children's smoking behavior in China. This study aims to estimate the current smoking prevalence among children, evaluate the association of parental migration and the smoking behavior of children and identify factors associated with smoking behavior among left-behind children (LBC). METHODS: A cross-sectional study was conducted in 6 cities in Anhui province during July and August, 2012...
2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27487183/self-reported-health-experiences-of-children-living-with-congenital-heart-defects-including-patient-reported-outcomes-in-a-national-cohort-study
#20
Rachel Louise Knowles, Valerija Tadic, Ailbhe Hogan, Catherine Bull, Jugnoo Sangeeta Rahi, Carol Dezateux
BACKGROUND: Understanding children's views about living with congenital heart defects (CHDs) is fundamental to supporting their successful participation in daily life, school and peer relationships. As an adjunct to a health and quality of life outcomes questionnaire, we asked school-age children who survived infant heart procedures to describe their experiences of living with CHDs. METHODS: In a UK-wide cohort study, children aged 10 to 14 years with CHDs self-completed postal questionnaires that included an open question about having a 'heart problem'...
2016: PloS One
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