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https://www.readbyqxmd.com/read/29049283/the-impact-of-muscle-relaxation-techniques-on-the-quality-of-life-of-cancer-patients-as-measured-by-the-fact-g-questionnaire
#1
Paula Parás-Bravo, Paloma Salvadores-Fuentes, Cristina Alonso-Blanco, María Paz-Zulueta, Miguel Santibañez-Margüello, Domingo Palacios-Ceña, Ester Boixadera-Planas, César Fernández-de-Las-Peñas
INTRODUCTION: Patients with cancer frequently suffer from emotional distress, characterized by psychological symptoms such as anxiety or depression. The presence of psychological symptoms combined with the complex nature of oncology processes can negatively impact patients' quality of life. We aimed to determine the impact of a relaxation protocol on improving quality of life in a sample of oncological patients treated in the Spanish National Public Health System. MATERIALS AND METHODS: We conducted a multicenter interventional study without a control group...
2017: PloS One
https://www.readbyqxmd.com/read/29037618/immediate-effect-of-mental-practice-with-and-without-mirror-therapy-on-muscle-activation-in-hemiparetic-stroke-patients
#2
Tamise Aguiar Caires, Luciane Fernanda Rodrigues Martinho Fernandes, Lislei Jorge Patrizzi, Rafael de Almeida Oliveira, Luciane Aparecida Pascucci Sande de Souza
Mental practice (MP) consists of the repeated mental rehearsal of a physical skill without movement, called motor imagery (MI). Studies show that MP and MI associated mirror therapy (MPMT) may improve muscle control of the upper limbs in hemiparesis. This study aimed to evaluate muscle activation during active flexion of the wrist (MA), MP, and MPMT in patients with history of stroke and hemiparesis. Individuals diagnosed with stroke showing sequelae of upper limb hemiparesis were enrolled. The flexor carpi ulnaris was analyzed using electromyography during tasks (MA, MP, MPMT) involving wrist flexion...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28987079/effectiveness-of-biofield-therapy-for-patients-diagnosed-with-fibromyalgia
#3
Fernando Sarmento, Hideaki Tanaka, Eduarda Cordeiro, Kiyoshi Suzuki
Context • Fibromyalgia (FM) is a disorder with an unknown etiology; symptoms include physical and psychological stress, widespread chronic pain, insomnia, and depression. Mind-body medicine and aerobic exercise have shown positive effects for symptom control. Several studies have reported positive effects for biofield therapy for FM, but when other studies have compared the treatment with a sham control, they have not found those beneficial effects. Objective • The study intended to examine the effects of a biofield therapy called Okada purifying therapy on patients' FM symptoms...
October 2, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28983271/-health-in-the-mirror-an-unconventional-approach-to-unmet-psychological-needs-in-oncology
#4
Valentina E Di Mattei, Letizia Carnelli, Paola Taranto, Martina Bernardi, Chiara Brombin, Federica Cugnata, Angela Noviello, Morag Currin, Giorgia Mangili, Emanuela Rabaiotti, Lucio Sarno, Massimo Candiani
Background: The introduction of aesthetic care programs for cancer patients inside hospitals could help patients cope with the side effects of both disease and treatment. The specific objective of this study is to evaluate whether a complementary and supportive program, called "Health in the Mirror," has a positive effect on participants by analyzing certain psychological variables. Methods: Eighty-eight female cancer patients were included in this analysis. The support program is composed of three group aesthetic interventions that address both physical and psychological aspects that accompany cancer and its treatment...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28980043/how-imaging-membrane-and-cell-processes-involved-in-electropermeabilization-can-improve-its-development-in-cell-biology-and-in-clinics
#5
Laure Gibot, Muriel Golzio, Marie-Pierre Rols
Cell membranes can be transiently permeabilized under the application of electric pulses. This process, called electropermeabilization or electroporation, allows hydrophilic molecules, such as anticancer drugs and DNA, to enter into cells and tissues. The method is nowadays used in clinics to treat cancers. Vaccination and gene therapy are other fields of application of DNA electrotransfer. A description of the mechanisms can be assayed by using different complementary systems with increasing complexities (models of membranes, cells cultivated in 2D and 3D culture named spheroids, and tissues in living mice) and different microscopy tools to visualize the processes from single molecules to entire animals...
2017: Advances in Anatomy, Embryology, and Cell Biology
https://www.readbyqxmd.com/read/28933176/-myocarditis-and-inflammatory-cardiomyopathy
#6
Dalibor Mlejnek, Jan Krejčí
Myocarditis is an inflammation of the heart muscle. The most common cause of myocarditis is viral infection in industrialized countries. Myocarditis with left ventricular dysfunction is called inflammatory cardiomyopathy and is the major cause of dilated cardiomyopathy. The clinical picture is very diverse, most often the patient present with signs of heart failure, arrhythmic symptoms and chest pains. Despite significant advances in non-invasive diagnostics, particularly magnetic resonance imaging, endomyocardial biopsy remains the gold standard of myocarditis diagnosis...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28891846/quality-of-life-in-rectal-cancer-patients-after-chemoradiation-watch-and-wait-policy-versus-standard-resection-a-matched-controlled-study
#7
MULTICENTER STUDY
Britt J P Hupkens, Milou H Martens, Jan H Stoot, Maaike Berbee, Jarno Melenhorst, Regina G Beets-Tan, Geerard L Beets, Stéphanie O Breukink
BACKGROUND: Fifteen to twenty percent of patients with locally advanced rectal cancer have a clinical complete response after chemoradiation therapy. These patients can be offered nonoperative organ-preserving treatment, the so-called watch-and-wait policy. The main goal of this watch-and-wait policy is an anticipated improved quality of life and functional outcome in comparison with a total mesorectal excision, while maintaining a good oncological outcome. OBJECTIVE: The aim of this study was to compare the quality of life of watch-and-wait patients with a matched-controlled group of patients who underwent chemoradiation and surgery (total mesorectal excision group)...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28879503/asthma-phenotypes-and-endotypes-implications-for-personalised-therapy
#8
Katrina Dean, Robert Niven
Asthma is increasingly recognised as a heterogeneous group of diseases with similar clinical presentations rather than a singular disease entity. Asthma was historically categorised by clinical symptoms; however, newer methods of subgrouping, describing and categorising the disease have sub-defined asthma. These sub-definitions are intermittently called phenotypes or endotypes, but the real meanings of these words are poorly understood. Novel treatments are currently and increasingly available, partly in the monoclonal antibody environment, and also some physical therapies (bronchial thermoplasty), but additionally small molecules are not far away from clinical practice...
September 6, 2017: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://www.readbyqxmd.com/read/28855584/non-equilibrium-inertial-separation-array-for-high-throughput-large-volume-blood-fractionation
#9
Baris R Mutlu, Kyle C Smith, Jon F Edd, Priyanka Nadar, Mcolisi Dlamini, Ravi Kapur, Mehmet Toner
Microfluidic blood processing is used in a range of applications from cancer therapeutics to infectious disease diagnostics. As these applications are being translated to clinical use, processing larger volumes of blood in shorter timescales with high-reliability and robustness is becoming a pressing need. In this work, we report a scaled, label-free cell separation mechanism called non-equilibrium inertial separation array (NISA). The NISA mechanism consists of an array of islands that exert a passive inertial lift force on proximate cells, thus enabling gentler manipulation of the cells without the need of physical contact...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28826701/outcomes-of-men-on-active-surveillance-for-low-risk-prostate-cancer-at-a-safety-net-hospital
#10
E Charles Osterberg, Nynikka R A Palmer, Catherine R Harris, Gregory P Murphy, Sarah D Blaschko, Carissa Chu, Isabel E Allen, Matthew R Cooperberg, Peter R Carroll, Benjamin N Breyer
PURPOSE: To characterize demographic, disease, and cancer outcomes of men on active surveillance (AS) at a safety-net hospital and characterize those who were lost to follow-up (LTFU). METHODS: From January 2004 to November 2014, 104 men with low-risk prostate cancer (PCa) were followed with AS at Zuckerberg San Francisco General Hospital (ZSFG). Criteria for AS have evolved over time; however, patients with diagnostic prostate-specific antigen (PSA) 10ng/mL or less, clinical stage T1/2, biopsy Gleason score 3 + 3 or 3 + 4, 33% or fewer positive cores, and 50% or less tumor in any single core were potentially eligible for AS...
August 17, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28826230/optimism-alongside-new-challenges-using-a-rehabilitation-framework-to-explore-experiences-of-a-qualitative-longitudinal-cohort-of-people-living-with-hiv-on-antiretroviral-treatment-in-lusaka-zambia
#11
Stephanie A Nixon, Virginia Bond, Patricia Solomon, Cathy Cameron, Chanda Mwamba, Jill Hanass-Hancock, Margaret C Maimbolwa, J Anitha Menon, Phillimon Simwaba, Robert Sinyinza, Margaret Siwale, Stephen Tattle, Tammy Yates
Previous research has demonstrated increased comorbidities related to the chronic effects of HIV. Rehabilitation science offers a useful approach for studying chronic illness. This longitudinal qualitative study used a rehabilitation science approach to explore the experiences over time of women and men living with HIV and on antiretroviral therapy (ART) in the high HIV-prevalence setting of Lusaka, Zambia. Thirty-five participants participated in a total of 99 in-depth interviews from 2012 to 2015. The central pattern that emerged across the participants' narratives was the paradoxical experience of profound optimism alongside significant new challenges...
August 21, 2017: AIDS Care
https://www.readbyqxmd.com/read/28812985/interventions-to-support-integrated-psychological-care-and-holistic-health-outcomes-in-paediatrics
#12
REVIEW
Roz Shafran, Sophie D Bennett, Mhairi McKenzie Smith
There are strong calls from many national and international bodies for there to be a 'holistic' and integrated approach to the understanding and management of psychological and physical health needs. Such holistic approaches are characterized by the treatment of the whole person, taking into account mental and social factors, rather than just the symptoms of a disease. Holistic approaches can impact on mental and physical health and are cost-effective. Several psychological interventions have demonstrated efficacy in improving holistic health outcomes, for example Cognitive Behaviour Therapy, Behavioural Therapies and Problem Solving Therapies...
August 16, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28806822/-multiple-myeloma-current-status-in-diagnostic-testing-and-therapy
#13
Michael Kehrer, Sebastian Koob, Andreas Strauss, Dieter Christian Wirtz, Jan Schmolders
Background Multiple myeloma is a haematological blood cancer of the bone marrow and is classified by the World Health Organisation (WHO) as a plasma cell neoplasm. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of an abnormal immunoglobulin called monoclonal protein or M protein. This ultimately causes multiple myeloma symptoms such as bone damage or kidney problems. The annual worldwide incidence of multiple myeloma is estimated to be 6 - 7/100,000 and accounts for 1% of all cancer...
October 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28770686/body-composition-changes-with-testosterone-replacement-therapy-following-spinal-cord-injury-and-aging-a-mini-review
#14
Tom E Nightingale, Pamela Moore, Joshua Harman, Refka Khalil, Ranjodh S Gill, Teodoro Castillo, Robert A Adler, Ashraf S Gorgey
Context Hypogonadism is a male clinical condition in which the body does not produce enough testosterone. Testosterone plays a key role in maintaining body composition, bone mineral density, sexual function, mood, erythropoiesis, cognition and quality of life. Hypogonadism can occur due to several underlying pathologies during aging and in men with physical disabilities, such as spinal cord injury (SCI). This condition is often under diagnosed and as a result, symptoms undertreated. Methods In this mini-review, we propose that testosterone replacement therapy (TRT) may be a viable strategy to improve lean body mass (LBM) and fat mass (FM) in men with SCI...
August 3, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28760092/when-chronic-pain-is-not-chronic-pain-lessons-from-3-decades-of-pain
#15
Alan J Taylor, Roger Kerry
The current move in physical therapy toward the biopsychosocial management of chronic pain has led some interpreters to call for a less hands-on approach, as awareness of central sensitization leads to specific management trends and a move away from pathoanatomical considerations. The authors of this Viewpoint suggest that no approach, no matter how vocal and evangelistic its followers, would likely be any more certain than what preceded it. This Viewpoint poses the question, why, when we (as a profession) appear (according to the new physical therapy gurus) to have been so wrong before, do we appear to believe that we are right this time? J Orthop Sports Phys Ther 2017;47(8):515-517...
August 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28752662/a-bayesian-approach-to-solve-proton-stopping-powers-from-noisy-multi-energy-ct-data
#16
Arthur Lalonde, Esther Bär, Hugo Bouchard
PURPOSE: To propose a new formalism allowing the characterization of human tissues from multienergy computed tomography (MECT) data affected by noise and to evaluate its performance in estimating proton stopping powers (SPR). METHODS: A recently published formalism based on principal component analysis called eigentissue decomposition (ETD) is adapted to the context of noise using a Bayesian estimator. The method, named Bayesian ETD, uses the maximum a posteriori fractions of eigentissues in each voxel to determine physical parameters relevant for proton beam dose calculation...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/28682718/the-ventricular-assist-device-in-the-life-of-the-child-a-phenomenological-pediatric-study
#17
Michael A van Manen
What is it like for a child to live with an artificial heart? The use of some medical therapies in children requires developmental considerations, is associated with psychosocial consequences, and calls for ethical sensitivities. A critical case is the ventricular assist device (VAD), a mechanical pump used to support the functioning of a failing heart. As a pediatric therapy, the device can be used as a temporary solution for poor heart function, a bridge to transplantation or recovery, or as a destination therapy...
May 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28609301/a-light-weight-compact-proton-gantry-design-with-a-novel-dose-delivery-system-for-broad-energetic-laser-accelerated-beams
#18
U Masood, T E Cowan, W Enghardt, K M Hofmann, L Karsch, F Kroll, U Schramm, J J Wilkens, J Pawelke
Proton beams may provide superior dose-conformity in radiation therapy. However, the large sizes and costs limit the widespread use of proton therapy (PT). The recent progress in proton acceleration via high-power laser systems has made it a compelling alternative to conventional accelerators, as it could potentially reduce the overall size and cost of the PT facilities. However, the laser-accelerated beams exhibit different characteristics than conventionally accelerated beams, i.e. very intense proton bunches with large divergences and broad-energy spectra...
July 7, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28576305/cystic-fibrosis-transmembrane-regulator-modulators-implications-for-the-management-of-depression-and-anxiety-in-cystic-fibrosis
#19
REVIEW
Jaideep S Talwalkar, Jonathan L Koff, Hochang B Lee, Clemente J Britto, Arielle M Mulenos, Anna M Georgiopoulos
BACKGROUND: Individuals with cystic fibrosis (CF) are at high risk for depression and anxiety, which are associated with worse medical outcomes. Novel therapies for CF hold great promise for improving physical health, but the effects of these therapies on mental health remain poorly understood. OBJECTIVE: This review aims to familiarize psychiatrists with the potential effect of novel CF therapies on depression and anxiety. METHODS: We discuss novel therapies that directly target the mutant CF protein, the CF transmembrane regulator (CFTR), which are called CFTR modulators...
July 2017: Psychosomatics
https://www.readbyqxmd.com/read/28489810/a-case-report-of-hereditary-neuropathy-with-liability-to-pressure-palsies-accompanied-by-type-2-diabetes-mellitus-and-psoriasis
#20
Jing Li, Bing Niu, Xiaoling Wang, Huaiqiang Hu, Bingzhen Cao
RATIONALE: Hereditary neuropathy with liability to pressure palsy (HNPP) is an episodic, multifocal neuropathy, with a typical clinical presentation of recurrent transient pressure palsies, which is induced by a PMP22 deletion. Another neuropathy caused by a PMP22 duplication is Charcot-Marie-Tooth disease type 1A (CMT1A). PMP22 is a gene coding a protein called peripheral myelin protein 22 (PMP22), which plays an essential role in the formation and maintenance of compact myelin. Coexistence of type 2 diabetes mellitus (T2DM) and CMT1A has been reported in many work, however HNPP patients with T2DM are rare, and comorbidity of HNPP and psoriasis has not been reported previously...
May 2017: Medicine (Baltimore)
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