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Javaid, A

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https://www.readbyqxmd.com/read/29144817/seasonal-variation-of-vitamin-d-and-serum-thyrotropin-levels-and-its-relationship-in-a-euthyroid-caucasian-population
#1
Gautam Das, Peter N Taylor, Heather Javaid, Brian P Tennant, John Geen, Andrew Aldridge, Onyebuchi Okosieme
OBJECTIVES: It is unclear whether seasonal variations in vitamin D concentrations affect the hypothalamo-pituitary-thyroid (HPT) axis. We investigated the seasonal variability of vitamin D and serum thyrotropin (TSH) levels and their inter-relationship. METHODS: Analysis of 401 patients referred with non-specific symptoms of tiredness who had simultaneous measurements of 25(OH)D3 and thyroid function. Patients were categorised according to the season of blood sampling and their vitamin D status...
November 16, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/29142550/clinical-outcome-of-23g-trans-conjunctival-pars-plana-vitrectomy-a-prospective-comparison-of-phaco-vitrectomy-with-only-vitrectomy-in-phakic-eyes
#2
Haroon Tayyab, Asad Aslam Khan, Rana Muhammad Mohsin Javaid
Objective: To evaluate the effectiveness and safety profile of combined phacoemulsification with 23G pars plana vitrectomy when compared to pars plana vitrectomy alone in phakic patients. Methods: This study was performed at Al-Ehsan Eye Hospital (tertiary care eye hospital in Lahore, Pakistan) from January 2016 to August 2016. A total of 40 eyes in two equal groups of 20 eyes each, were enrolled in this prospective study. Group-A underwent combined phaco-vitrectomy, whereas Group-B underwent vitrectomy only for various vitreoretinal pathologies...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29141246/evaluation-of-temporal-virological-responses-to-interferon-%C3%AE-2b-plus-ribavirin-among-genotype-3a-hepatitis-c-virus-infected-patients
#3
Abida Raza, Muhammad Ovais, Hafsa Aziz, Asim Anwar, Javaid Irfan, Irshad Ahmad, Muhammad Mukhtar
OBJECTIVES: The present study aimed to examine the impact of rapid virological response (RVR) and early virological response (EVR) on sustained virological response (SVR) in chronic hepatitis C genotype 3a individuals. METHODS: The patients were given antiviral therapy with IFN-α-2b, 3 million units 3 times a week and 800-1,200 mg of ribavirin daily adjusted to the patient's body weight (<60 kg 800 mg day-1, and >60 kg 1,200 day-1). The patients received this combination therapy for 24 weeks...
November 16, 2017: Intervirology
https://www.readbyqxmd.com/read/29137508/health-professional-education-and-universal-health-coverage-a-summary-of-challenges-and-selected-case-studies
#4
Arthika Sripathy, Joachim Marti, Hannah Patel, Javaid I Sheikh, Ara W Darzi
Low- and middle-income countries are experiencing serious shortages in meeting health workforce requirements for universal health coverage. We examine how national-level policies can address these deficiencies and support the development of an appropriately skilled health workforce in line with population needs. We discuss three innovative, government-led solutions that are designed to align health workforce training with the demands of universal health coverage. Specifically, we discuss two initiatives to train and retain doctors in rural areas of Thailand, the large-scale training of community health workers within multidisciplinary primary health care teams in Brazil, and the introduction of a postgraduate diploma program in primary care for nurses in India...
November 2017: Health Affairs
https://www.readbyqxmd.com/read/29046679/overexpression-of-npr1-in-brassica-juncea-confers-broad-spectrum-resistance-to-fungal-pathogens
#5
Sajad Ali, Zahoor A Mir, Anshika Tyagi, Hailay Mehari, Rajendra P Meena, Javaid A Bhat, Prashant Yadav, Pradeep Papalou, Sandhya Rawat, Anita Grover
Brassica juncea (Indian mustard) is a commercially important oil seed crop, which is highly affected by many biotic stresses. Among them, Alternaria leaf blight and powdery mildew are the most devastating diseases leading to huge yield losses in B. juncea around the world. In this regard, genetic engineering is a promising tool that may possibly allow us to enhance the B. juncea disease resistance against these pathogens. NPR1 (non-expressor of pathogen-related gene 1) is a bonafide receptor of salicylic acid (SA) which modulates multiple immune responses in plants especially activation of induced and systemic acquired resistance (SAR)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29045121/wafer-scale-synthesis-of-semiconducting-sno-monolayers-from-interfacial-oxide-layers-of-metallic-liquid-tin
#6
Torben Daeneke, Paul Atkin, Rebecca Orrell-Trigg, Ali Zavabeti, Taimur Ahmed, Sumeet Walia, Maning Liu, Yasuhiro Tachibana, Maria Javaid, Andrew D Greentree, Salvy P Russo, Richard B Kaner, Kourosh Kalantar-Zadeh
Atomically thin semiconductors are one of the fastest growing categories in materials science due to their promise to enable high-performance electronic and optical devices. Furthermore, a host of intriguing phenomena have been reported to occur when a semiconductor is confined within two dimensions. However, the synthesis of large area atomically thin materials remains as a significant technological challenge. Here we report a method that allows harvesting monolayer of semiconducting stannous oxide nanosheets (SnO) from the interfacial oxide layer of liquid tin...
October 18, 2017: ACS Nano
https://www.readbyqxmd.com/read/29039317/progression-pattern-of-rheumatoid-arthritis-a-study-of-500-pakistani-patients
#7
Fazal Jalil, Maria Arshad, Attya Bhatti, Muhsin Jamal, Mushtaq Ahmed, Javaid Mehmood Malik, Sajid Ali, Fazal Akbar, Peter John
To estimate the most prevalent age of patients and disease status and progression in terms of severity at different age groups in the Pakistani Rheumatoid Arthritis (RA) patients. A total of five hundred (500) RA patients were enrolled during October, 2009 to October, 2013. A screening questionnaire was filled for each patient satisfying America College of Rheumatology (ACR) criteria under the supervision of certified rheumatologists. Epidemiological and demographic variables were statistically analyzed for correlation with progression of the disease using SPSS ver 17...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28974401/the-failing-medial-compartment-in-the-varus-knee-and-its-association-with-cam-deformity-of-the-hip
#8
Jonathan S Palmer, Antony J Palmer, Luke D Jones, Sujin Kang, Nicholas Bottomley, William M Jackson, A Paul Monk, David J Beard, Kassim Javaid, Sion Glyn-Jones, Andrew J Price
BACKGROUND: Since 2011, the knee service at the Nuffield Orthopaedic Centre has been offering a neutralising medial opening wedge high tibial osteotomy (HTO) to a specific group of patients with genu varum and early knee osteoarthritis. An observation was made concerning this group of patients and the presence of CAM deformity at the hip. The aim of this study is to establish whether or not any association exists between the OA phenotype shared by our HTO group and the incidence of CAM deformity at the hip...
September 30, 2017: Knee
https://www.readbyqxmd.com/read/28973983/an-energy-scaled-and-expanded-vector-based-forwarding-scheme-for-industrial-underwater-acoustic-sensor-networks-with-sink-mobility
#9
Zahid Wadud, Sajjad Hussain, Nadeem Javaid, Safdar Hussain Bouk, Nabil Alrajeh, Mohamad Souheil Alabed, Nadra Guizani
Industrial Underwater Acoustic Sensor Networks (IUASNs) come with intrinsic challenges like long propagation delay, small bandwidth, large energy consumption, three-dimensional deployment, and high deployment and battery replacement cost. Any routing strategy proposed for IUASN must take into account these constraints. The vector based forwarding schemes in literature forward data packets to sink using holding time and location information of the sender, forwarder, and sink nodes. Holding time suppresses data broadcasts; however, it fails to keep energy and delay fairness in the network...
September 30, 2017: Sensors
https://www.readbyqxmd.com/read/28970158/predictors-of-poor-treatment-outcomes-in-multidrug-resistant-tuberculosis-patients-a-retrospective-cohort-study
#10
Arshad Javaid, Irfan Ullah, Haleema Masud, Anila Basit, Waqas Ahmad, Zahid Ahmad Butt, Muhammad Qasim
OBJECTIVES: We aimed to determine the characteristics, treatment outcomes and risk factors for poor treatment outcomes among multidrug-resistant tuberculosis (MDR-TB) patients in the Khyber Pakhtunkhwa province, Pakistan. METHODS: A retrospective cohort study including all patients with MDR-TB attended at the MDR-TB unit in Peshawar was conducted between January 2012 and April 2014. Patients were followed until an outcome of TB treatment was recorded as successful (cured or completed) or unsuccessful...
September 29, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28955077/comparison-of-characteristics-of-femtosecond-laser-assisted-anterior-capsulotomy-versus-manual-continuous-curvilinear-capsulorrhexis-a-meta-analysis-of-5-year-results
#11
Muhammad Hassaan Ali, Samee Ullah, Usman Javaid, Mamoona Javaid, Samreen Jamal, Nadeem Hafeez Butt
OBJECTIVE: To perform a meta-analysis on the precision and safety of femtosecond laser-assisted anterior capsulotomy versus conventional manual continuous curvilinear capsulorrhexis. METHODS: This meta-analysis was conducted from February 2010 to November 2014. Literature search on PubMed, Google Scholar, ExcerptaMedica database and Cochrane Library was done to identify randomised controlled trials and case-control studies. SPSS 20 was used for data analysis. RESULTS: Of the 10 articles included, there were 3(30%) randomised controlled trials and 7(70%) non-randomised controlled trials...
October 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28931696/description-of-an-urgent-start-peritoneal-dialysis-program-in-singapore
#12
Muhammad M Javaid, Evan Lee, Behram A Khan, Srinivas Subramanian
No abstract text is available yet for this article.
September 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28918832/streptococcus-anginosus-group-bacterial-infections
#13
Tasaduq Fazili, Scott Riddell, Deanna Kiska, Tim Endy, Luca Giurgea, Calden Sharngoe, Waleed Javaid
BACKGROUND: The Streptococcus anginosus group (SAG) causes a variety of infections in adults. To better understand the burden of SAG infections and their associated morbidity and mortality, we conducted a retrospective analysis of these infections in adults at a tertiary care center. METHODS: A retrospective review of all cultures positive for SAG in adults and a corresponding review of the patients' medical records were conducted at a tertiary care facility in central New York...
September 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28878944/development-and-validation-of-a-clinical-risk-score-to-predict-mortality-after-percutaneous-coronary-intervention
#14
Joshua J S Wall, Javaid Iqbal, Michael Andrews, Dawn Teare, Mina Ghobrial, Thomas Hinton, Samuel Turton, Leila Quffa, Magdi El-Omar, Douglas G Fraser, Anjan Siotia, Julian Gunn
OBJECTIVE: To develop and validate a contemporary clinical risk score to predict mortality after percutaneous coronary intervention (PCI). METHODS: Using data collected from patients undergoing PCI at the South Yorkshire Cardiothoracic Centre, Sheffield, UK, between January 2007 and September 2013, a risk score was developed to predict mortality. Logistic regression was used to evaluate the effect of each variable upon 30-day mortality. A backwards stepwise logistic regression model was then used to build a predictive model...
2017: Open Heart
https://www.readbyqxmd.com/read/28873034/the-absence-of-hcv-rna-and-ns5a-protein-in-peripheral-blood-mononuclear-cells-is-a-prognostic-tool-for-sustained-virological-response
#15
Azhar Mehmood, Muhammad Javaid Asad, Muhammad Ovais, Nasib Zaman, Hafsa Aziz, Javaid Irfan, Irshad Ahmad, Abida Raza
Hepatitis C Virus (HCV) infection is a major health concern worldwide. The presence of both HCV viral RNA and NS5A proteins in peripheral blood mononuclear cells (PBMCs) indicate the efficacy of the treatment during sustained virological response (SVR) and end of treatment response (ETR). The main objective of this study was to detect the absence or presence of HCV RNA and NS5A proteins in PBMCs. Blood samples were taken from selected patients (Islamabad, Pakistan) before treatment, at ETR, and during SVR. Two hundred HCV responders to pegylated IFN-α-2a plus ribavirin were selected...
October 2017: Viral Immunology
https://www.readbyqxmd.com/read/28865897/bare-metal-versus-drug-eluting-stents-for-st-segment-elevation-myocardial-infarction-in-the-total-trial
#16
Shahar Lavi, Javaid Iqbal, John A Cairns, Warren J Cantor, Asim N Cheema, Raul Moreno, Brandi Meeks, Robert C Welsh, Sasko Kedev, Saqib Chowdhary, Goran Stankovic, J D Schwalm, Yan Liu, Sanjit S Jolly, Vladimír Džavík
BACKGROUND: The safety and efficacy of drug eluting stents (DES) in the setting of ST elevation myocardial infarction (STEMI) is not well established. METHODS: In the TOTAL trial, patients presenting with STEMI were randomized to routine thrombectomy versus PCI alone. In this post-hoc analysis, propensity matching was used to assess relative safety and efficacy according to type of stent used. RESULTS: Each propensity-matched cohort included 2313 patients...
December 1, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28865411/frequency-of-hla-dq%C3%AE-1-0201-and-dq%C3%AE-1-0301-alleles-and-total-serum-ige-in-patients-with-bronchial-asthma-a-pilot-study-from-pakistan
#17
Bushra Mubarak, Nadeem Afzal, Khursheed Javaid, Rakhshanda Talib, Rabia Aslam, Waqas Latif, Saba Khaliq
In Pakistan about 3.7% of the population is suffering from asthma, a chronic inflammatory disorder of airways. Asthma has wide spectrum of predisposing factors including environment and genetics. Many studies have been performed to determine association of asthma with serum IgE and major histocompatibility complex (MHC) alleles but conflicting results were reported. Therefore, present study was designed to determine frequency of HLA-DQβ1*0201 and DQβ1*0301 alleles in patients with bronchial asthma. This case control study included 85 asthmatic patients and 85 healthy controls...
August 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28851913/a-study-of-size-dependent-properties-of-mos2-monolayer-nanoflakes-using-density-functional-theory
#18
M Javaid, Daniel W Drumm, Salvy P Russo, Andrew D Greentree
Novel physical phenomena emerge in ultra-small sized nanomaterials. We study the limiting small-size-dependent properties of MoS2 monolayer rhombic nanoflakes using density-functional theory on structures of size up to Mo35S70 (1.74 nm). We investigate the structural and electronic properties as functions of the lateral size of the nanoflakes, finding zigzag is the most stable edge configuration, and that increasing size is accompanied by greater stability. We also investigate passivation of the structures to explore realistic settings, finding increased HOMO-LUMO gaps and energetic stability...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28844035/state-of-the-art-optimal-medical-therapy-competing-with-or-complementary-to-revascularisation-in-patients-with-coronary-artery-disease
#19
Javaid Iqbal, Robert Widmer, Bernard J Gersh
The role of coronary revascularisation with PCI and CABG in patients with stable and unstable coronary artery disease (CAD) is well established and there is a general consensus among guidelines as regards the indications for coronary revascularisation. Although revascularisation has undoubtedly revolutionised the treatment of CAD, it is vital to understand the recent advances and importance of the concomitant use of evidence-based optimal medical therapy (OMT). In contemporary practice, OMT should include an antiplatelet agent (or dual antiplatelet therapy when indicated) and a lipid-lowering drug for all patients, and a beta-blocker and an ACE inhibitor (or angiotensin receptor blocker) for the vast majority of patients, along with addressing cardiac risk factors and lifestyle management...
August 25, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28825790/one-step-growth-of-iron-nickel-bimetallic-nanoparticles-on-feni-alloy-foils-highly-efficient-advanced-electrodes-for-the-oxygen-evolution-reaction
#20
Umair Yaqub Qazi, Cheng-Zong Yuan, Naseeb Ullah, Yi-Fan Jiang, Muhammad Imran, Akif Zeb, Sheng-Jie Zhao, Rahat Javaid, An-Wu Xu
Electrochemical water splitting is an important process to produce hydrogen and oxygen for energy storage and conversion devices. However, it is often restricted by the oxygen evolution reaction (OER) due to its sluggish kinetics. To overcome the problem, precious metal oxide-based electrocatalysts, such as RuO2 and IrO2, are widely used. The lack of availability and the high cost of precious metals compel researchers to find other resources for the development of cost-effective, environmentally friendly, earth-abundant, nonprecious electrocatalysts for OER...
August 30, 2017: ACS Applied Materials & Interfaces
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