keyword
MENU ▼
Read by QxMD icon Read
search

Javaid, A

keyword
https://www.readbyqxmd.com/read/28628732/understanding-neurophobia-reasons-behind-impaired-understanding-and-learning-of-neuroanatomy-in-cross-disciplinary-healthcare-students
#1
Muhammad Asim Javaid, Shelly Chakraborty, John F Cryan, Harriët Schellekens, André Toulouse
Recent studies have highlighted a fear or difficulty with the study and understanding of neuroanatomy among medical and healthcare students. This has been linked with a diminished confidence of clinical practitioners and students to manage patients with neurological conditions. The underlying reasons for this difficulty have been queried among a broad cohort of medical, dental, occupational therapy, and speech and language sciences students. Direct evidence of the students' perception regarding specific difficulties associated with learning neuroanatomy has been provided and some of the measures required to address these issues have been identified...
June 19, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28620563/pharmacological-threat-to-lungs-a-case-series-and-literature-review
#2
REVIEW
Omar Irfan, Jaleed A Gilani, Abeel Irshad, Babar Irfan, Javaid A Khan
Drug-induced organ damage stands as a prevalent yet much-neglected issue globally. Keeping in view it's rising frequency, health care providers stand obliged to be well versed with the de-merits of the agents they prescribe. Drug therapies causing damage present with a non-specific clinical presentation, histological findings or radiology, which further elaborates on the necessity of a conscientious diagnosis. Pulmonary architecture ranging from the airways, lung parenchyma, mediastinum, pleura, pulmonary vasculature or the neuromuscular system, all can fall victim to the dreaded outcomes of this menace...
May 9, 2017: Curēus
https://www.readbyqxmd.com/read/28619767/association-of-hypercapnia-on-admission-with-increased-length-of-hospital-stay-and-severity-in-patients-admitted-with-community-acquired-pneumonia-a-prospective-observational-study-from-pakistan
#3
Nousheen Iqbal, Muhammad Irfan, Ali Bin Sarwar Zubairi, Safia Awan, Javaid A Khan
OBJECTIVE: To determine whether the presence of hypercapnia on admission in adult patients admitted to a university-based hospital in Karachi, Pakistan with community-acquired pneumonia (CAP) correlates with an increased length of hospital stay and severity compared with no hypercapnia on admission. STUDY DESIGN: A prospective observational study. SETTINGS: Tertiary care hospital in Karachi, Pakistan. METHODS: Patients who met the inclusion criteria were enrolled in the study...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28612306/bone-density-and-body-composition-in-newly-licenced-professional-jockeys
#4
K A Jackson, M T Sanchez-Santos, A L MacKinnon, A Turner, K Kuznik, S Ellis, C Box, J Hill, M K Javaid, C Cooper, N K Arden, J L Newton
The primary objective is the description of bone mineral density (BMD) and body composition in newly licensed jockeys. One in three male, flat jockeys has a very low bone mineral density. Further research is needed to assess the short-term risk of fractures and long-term health implications of these findings. INTRODUCTION: Describe bone mineral density (BMD) and body composition in entry-level male and female, flat and jump jockeys in Great Britain. METHODS: Data was collected on jockeys applying for a professional jockey license between 2013 and 2015...
June 13, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28611779/diametric-role-of-the-latency-associated-protein-acr1-of-mycobacterium-tuberculosis-in-modulating-the-functionality-of-pre-and-post-maturational-stages-of-dendritic-cells
#5
Mohammed Amir, Mohammad Aqdas, Sajid Nadeem, Kaneez F Siddiqui, Nargis Khan, Javaid A Sheikh, Javed N Agrewala
It is instrumental for the Mycobacterium tuberculosis (Mtb) to persist within its host in dormancy. Mtb represses most of its metabolic machinery during latency, but upregulates the expression of latency-associated protein alpha-crystallin protein (Acr1). Therefore, it is imperative to understand how throughout dormancy, Mtb employs Acr1 to regulate the host immunity. This study reveals that Acr1 exhibits divergent effect on the pre- and post-maturation stages of dendritic cells (DCs). In the current study, we demonstrate that early encounter of bone marrow cells with Acr1 while differentiating into DCs (AcrDC(pre)), leads to impairment in their maturation...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28598909/cardiorespiratory-reference-data-in-older-adults-the-generation-100-study
#6
Dorthe Stensvold, Silvana Bucher Sandbakk, Hallgeir Viken, Nina Zisko, Line Skarsem Reitlo, Javaid Nauman, Svein Erik Gaustad, Erlend Hassel, Marcel Moufack, Eivind Brønstad, Nils Petter Aspvik, Vegard Malmo, Sigurd Loe Steinshamn, Asbjørn Støylen, Sigmund Alfred Anderssen, Jorunn L Helbostad, Øivind Rognmo, Ulrik Wisløff
PURPOSE: Cardiorespiratory fitness (CRF) is regarded a clinical vital sign, and accurate reference values for all age groups are essential. Little data exist on CRF and cardiorespiratory function in older adults. The aim of this study was to provide normative values for CRF and cardiorespiratory function in older adults, including people with history of cardiovascular diseases. METHODS: In total, 1537 (769 women) participants aged 70-77 underwent clinical examinations and cardiopulmonary exercise tests...
June 9, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28592592/late-systolic-myocardial-loading-is-associated-with-left-atrial-dysfunction-in-hypertension
#7
Julio A Chirinos, Timothy S Phan, Amer A Syed, Zeba Hashmath, Harry G Oldland, Maheswara R Koppula, Ali Tariq, Khuzaima Javaid, Rachana Miller, Swapna Varakantam, Anjaneyulu Dunde, Vadde Neetha, Scott R Akers
BACKGROUND: Late systolic load has been shown to cause diastolic dysfunction in animal models. Although the systolic loading sequence of the ventricular myocardium likely affects its coupling with the left atrium (LA), this issue has not been investigated in humans. We aimed to assess the relationship between the myocardial loading sequence and LA function in human hypertension. METHODS AND RESULTS: We studied 260 subjects with hypertension and 19 normotensive age- and sex-matched controls...
June 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28582758/rheumatoid-arthritis-recent-advances-on-its-etiology-role-of-cytokines-and-pharmacotherapy
#8
REVIEW
Javaid Alam, Ibrahim Jantan, Syed Nasir Abbas Bukhari
An autoimmune disease is defined as a clinical syndrome resulted from an instigation of both T cell and B cell or individually, in the absence of any present infection or any sort of distinguishable cause. Clonal deletion of auto reactive cells remains the central canon of immunology for decades, keeping the role of T cell and B cell aside, which are actually the guards to recognize the entry of foreign body. According to NIH, 23.5 million Americans are all together affected by these diseases. They are rare, but with the exception of RA...
June 2, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28575224/response-to-antenatal-cholecalciferol-supplementation-is-associated-with-common-vitamin-d-related-genetic-variants
#9
Rebecca J Moon, Nicholas C Harvey, Cyrus Cooper, Stefania D'Angelo, Elizabeth M Curtis, Sarah R Crozier, Sheila J Barton, Sian M Robinson, Keith M Godfrey, Nikki J Graham, John W Holloway, Nicholas J Bishop, Stephen Kennedy, Aris T Papageorghiou, Inez Schoenmakers, Robert Fraser, Saurabh V Gandhi, Ann Prentice, Hazel M Inskip, M Kassim Javaid
Context: Single nucleotide polymorphisms (SNP) in genes related to vitamin D metabolism have been associated with serum 25-hydroxyvitamin D [25(OH)D] concentration, but these relationships have not been examined following antenatal cholecalciferol supplementation. Objective: To determine whether SNPs in DHCR7, CYP2R1, CYP24A1 and GC are associated with the response to gestational cholecalciferol supplementation. Design: Within-randomization-group analysis of the MAVIDOS trial of antenatal cholecalciferol supplementation...
May 29, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28549206/assessment-of-allelic-diversity-among-drought-resistant-cotton-genotypes-using-microsatellite-markers
#10
A Javaid, F S Awan, F M Azhar, I A Khan
Drought, in conjunction with high temperature, is an important environmental constraint to cotton production. Development of cotton varieties with increased tolerance against adverse environmental conditions has been proposed as effective strategy for ensuring reliable yields. In the present study, 30 simple sequence repeat (SSR) primers were used to estimate genetic divergence among 22 cotton genotypes for drought stress tolerance. Genetic diversity is a prerequisite for developing drought resistant cotton genotypes...
May 25, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28506259/detection-of-antibacterial-activities-of-miswak-kalonji-and-aloe-vera-against-oral-pathogens-anti-proliferative-activity-against-cancer-cell-line
#11
Sameen Amjed, Kashaf Junaid, Junaid Jafar, Tuaha Amjad, Waqas Maqsood, Nadia Mukhtar, Kanza Tariq, Musarrat Sharif, Sana Javaid Awan, Farheen Ansari
BACKGROUND: Emerging drug resistance and hindrance of treatment is provoking scientists to search new, less expensive medicinally active compounds. Dental diseases caused by oral pathogens are very frequent chronic infections around the world. The medical potentials of a lot of Pakistani local herbs and herbal combinations is relatively unknown, hence attempted to explore. A study was designed to investigate potential role of local medicinal herbs for example Miswak, Kalonji & Aloe vera as antimicrobial, antioxidant and anti-proliferative agents against oral pathogens and cancer cell line...
May 15, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28479406/from-cookies-to-carrots-the-effect-of-inhibitory-control-training-on-children-s-snack-selections
#12
L Porter, C Bailey-Jones, G Priudokaite, S Allen, K Wood, K Stiles, O Parvin, M Javaid, F Verbruggen, N S Lawrence
Children consume too much sugar and not enough fruit and vegetables, increasing their risk of adverse health outcomes. Inhibitory control training (ICT) reduces children's and adults' intake of energy-dense foods in both laboratory and real-life settings. However, no studies have yet examined whether ICT can increase healthy food choice when energy-dense options are also available. We investigated whether a food-specific Go/No-Go task could influence the food choices of children aged 4-11, as measured by a hypothetical food choice task using healthy and unhealthy food images printed on cards...
May 4, 2017: Appetite
https://www.readbyqxmd.com/read/28473035/the-combined-association-of-skeletal-muscle-strength-and-physical-activity-on-mortality-in-older-women-the-hunt2-study
#13
Trine Karlsen, Javaid Nauman, Håvard Dalen, Arnulf Langhammer, Ulrik Wisløff
OBJECTIVE: To assess the isolated and combined associations of leg and arm strength with adherence to current physical activity guidelines with all-cause and cause-specific mortality in healthy elderly women. PATIENTS AND METHODS: This was a prospective cohort study of 2529 elderly women (72.6±4.8 years) from the Norwegian Healthy survey of Northern Trøndelag (second wave) (HUNT2) between August 15, 1995, and June 18, 1997, with a median of 15.6 years (interquartile range, 10...
May 2017: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/28468686/cucumber-mosaic-virus-and-its-2b-protein-alter-emission-of-host-volatile-organic-compounds-but-not-aphid-vector-settling-in-tobacco
#14
Trisna Tungadi, Simon C Groen, Alex M Murphy, Adrienne E Pate, Javaid Iqbal, Toby J A Bruce, Nik J Cunniffe, John P Carr
BACKGROUND: Aphids, including the generalist herbivore Myzus persicae, transmit cucumber mosaic virus (CMV). CMV (strain Fny) infection affects M. persicae feeding behavior and performance on tobacco (Nicotiana tabacum), Arabidopsis thaliana and cucurbits in varying ways. In Arabidopsis and cucurbits, CMV decreases host quality and inhibits prolonged feeding by aphids, which may enhance virus transmission rates. CMV-infected cucurbits also emit deceptive, aphid-attracting volatiles, which may favor virus acquisition...
May 3, 2017: Virology Journal
https://www.readbyqxmd.com/read/28460210/hypoxic-hepatitis-its-biochemical-profile-causes-and-risk-factors-of-mortality-in-critically-ill-patients-a-cohort-study-of-565-patients
#15
Mohammed M Aboelsoud, Amen I Javaid, Mazen O Al-Qadi, James H Lewis
PURPOSE: A retrospective analysis of critically-ill patients with hypoxic hepatitis (HH) to characterize the biochemical profile and to identify predictors of mortality using the Medical Information Mart for Intensive Care III database. METHODS: HH was defined as a rapid increase in AST/ALT≥800IU/L after exclusion of other causes. We investigated the correlation between various clinical and laboratory parameters and mortality rates using regression models. RESULTS: Among 38,645 ICU-patients, 565 (1...
April 26, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28446642/cotargeting-mtorc-and-egfr-signaling-as-a-therapeutic-strategy-in-hnscc
#16
Adam D Swick, Prashanth J Prabakaran, Margot C Miller, Amal M Javaid, Michael M Fisher, Emmanuel Sampene, Irene M Ong, Rong Hu, Mari Iida, Kwangok P Nickel, Justine Y Bruce, Deric L Wheeler, Randall J Kimple
Head and neck squamous cell carcinomas (HNSCC) are frequently altered along the PI3K/AKT/mTORC signaling axis. Despite excellent preclinical data, the use of compounds targeting this pathway as monotherapy has been underwhelming in initial clinical trials, and identification of predictive biomarkers remains challenging. To investigate mTORC-specific inhibition, we tested catalytic mTORC (AZD8055) and PI3K/mTORC (NVP-BEZ-235) inhibitors ± cetuximab in a panel of HNSCC cell lines and patient-derived xenografts (PDX)...
April 26, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28443622/the-rudy-study-using-digital-technologies-to-enable-a-research-partnership
#17
Harriet J A Teare, Joanna Hogg, Jane Kaye, Raashid Luqmani, Elaine Rush, Alison Turner, Laura Watts, Melanie Williams, M Kassim Javaid
Patients have extensive experience of their disease that can enhance the design and execution of research leading to significant innovations and efficiencies in the research process. The research community on the whole have been slow to adopt practices that enable patients to become active partners in research. Digital technologies are providing the means to do this more easily and so are increasingly being used to interact with patients and involve them in the design and execution of research. The RUDY (Rare UK Diseases of bone, joints and blood vessels) study's pioneering approach applies a custom-developed electronic platform where patients can contribute information over time about their disease experience, lifestyle and clinical history...
June 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28443288/rubisco-activases-aaa-chaperones-adapted-to-enzyme-repair
#18
REVIEW
Javaid Y Bhat, Gabriel Thieulin-Pardo, F Ulrich Hartl, Manajit Hayer-Hartl
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), the key enzyme of the Calvin-Benson-Bassham cycle of photosynthesis, requires conformational repair by Rubisco activase for efficient function. Rubisco mediates the fixation of atmospheric CO2 by catalyzing the carboxylation of the five-carbon sugar ribulose-1,5-bisphosphate (RuBP). It is a remarkably inefficient enzyme, and efforts to increase crop yields by bioengineering Rubisco remain unsuccessful. This is due in part to the complex cellular machinery required for Rubisco biogenesis and metabolic maintenance...
2017: Frontiers in Molecular Biosciences
https://www.readbyqxmd.com/read/28442329/association-of-telomere-length-with-myocardial-infarction-a-prospective-cohort-from-the-population-based-hunt-2-study
#19
REVIEW
Ida Beate Øyen Østhus, Stian Lydersen, Håvard Dalen, Javaid Nauman, Ulrik Wisløff
As possible markers of biological age, telomere length (TL) has been associated with age-related diseases such as myocardial infarction (MI) with conflicting findings. We sought to assess the relationship between TL and risk of future MI in 915 healthy participants (51.7% women) 65 years or older from a population-based prospective cohort (the HUNT 2 study, Norway). Mean TL was measured by quantitative PCR expressed as relative T (telomere repeat copy number) to S (single copy gene number) ratio, and log-transformed...
April 22, 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/28425873/rapid-detection-of-mycobacterium-tuberculosis-and-rifampicin-resistance-in-extrapulmonary-tuberculosis-and-sputum-smear-negative-pulmonary-suspects-using-xpert-mtb-rif
#20
Irfan Ullah, Arshad Javaid, Haleema Masud, Mazhar Ali, Anila Basit, Waqas Ahmad, Faisal Younis, Rehana Yasmin, Afsar Khan, Abdul Jabbar, Masroor Husain, Zahid Ahmad Butt
BACKGROUND: Tuberculosis (TB) is a serious public health problem in developing countries such as Pakistan. Rapid diagnosis of TB and detection of drug resistance are very important for timely and appropriate management of multidrug-resistant TB (MDR-TB). OBJECTIVE: The purpose of this study was to determine the diagnostic efficacy of the Xpert MTB/RIF assay for rapid diagnosis of TB and detection of rifampicin (RIF) resistance in extrapulmonary and smear-negative pulmonary TB suspects...
April 2017: Journal of Medical Microbiology
keyword
keyword
112112
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"