keyword
MENU ▼
Read by QxMD icon Read
search

Osteomyelitis in childrens

keyword
https://www.readbyqxmd.com/read/28620059/anakinra-in-a-cohort-of-children-with-chronic-nonbacterial-osteomyelitis
#1
Manuela Pardeo, Denise Pires Marafon, Virginia Messia, Maria Carmen Garganese, Fabrizio De Benedetti, Antonella Insalaco
OBJECTIVE: To report efficacy and safety in patients with chronic nonbacterial osteomyelitis (CNO) unresponsive to nonsteroidal antiinflammatory drugs (NSAID) and bisphosphonates and/or glucocorticoids treated with anakinra. METHODS: Nine patients (6 females) with refractory CNO were treated with anakinra for at least 6 months. We recorded, at baseline and after 6 months of treatment, clinical and laboratory features, and number and distribution of bone lesions detected by 99mTc-MDP bone scintigraphy...
June 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28607765/paediatric-bone-and-joint-infection
#2
REVIEW
Alexios D Iliadis, Manoj Ramachandran
Despite advances in understanding and management, paediatric osteoarticular infections continue to pose diagnostic difficulties for clinicians. Delays in diagnosis can lead to potentially devastating morbidity.No single investigation, including joint aspiration, is sufficiently reliable to diagnose conclusively paediatric bone and joint infection. Diagnosis should be based on a combination of clinical signs, imaging and laboratory investigations. Algorithms should supplement, and not replace, clinical decision making in all cases...
January 2017: EFORT open reviews
https://www.readbyqxmd.com/read/28594525/update-in-pediatric-musculoskeletal-infections-when-it-is-when-it-isn-t-and-what-to-do
#3
Alexandre Arkader, Christopher M Brusalis, William C Warner, James H Conway, Kenneth Noonan
Musculoskeletal infections, including osteomyelitis, septic arthritis, and pyomyositis, are a substantial cause of morbidity in children and adolescents. The increased virulence of infectious agents and the increased prevalence of antimicrobial-resistant pathogens, particularly methicillin-resistant Staphylococcus aureus, have resulted in a more complicated clinical course for diagnosis and management, which is evidenced by an increased length of hospital stays, incidence of complications, and number of surgical interventions...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28576541/a-case-of-acute-clival-osteomyelitis-in-a-7-year-old-boy-secondary-to-infection-of-a-thornwaldt-cyst
#4
Yasmine Benadjaoud, Nathalie Klopp-Dutote, Morgane Choquet, Elodie Brunel, Raphaël Guiheneuf, Cyril Page
Clival osteomyelitis is a potentially life-threatening infection that can occur in healthy children. It can be related to congenital anomalies. We report the case of a 7-year-old boy with Streptococcus intermedius and Fusobacterium clival osteomyelitis arising from a Thornwaldt cyst situated in a fossa navicularis magna of the occipital bone. Multidisciplinary management is necessary to ensure rapid improvement and complete healing.
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28556448/non-typhoidal-salmonella-infections-in-children-review-of-literature-and-recommendations-for-management
#5
REVIEW
Sophie Ch Wen, Emma Best, Clare Nourse
Non-typhoidal Salmonellae are a major cause of infectious diarrhoea worldwide and can cause invasive diseases, including bacteraemia, meningitis and osteomyelitis. Young or immunocompromised children and those with underlying conditions such as sickle cell disease are particularly vulnerable to invasive disease. There has been an increase in the rate of resistant non-typhoidal Salmonella, which is associated with invasive disease and hospitalisation. The intracellular nature of non-typhoidal Salmonella protects against extracellular antibiotics and can facilitate disease relapse, particularly meningitis...
May 29, 2017: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/28534215/-acute-haematogenous-osteomyelitis-in-children-diagnostic-algorithm-and-treatment-strategies
#6
M Willegger, A Kolb, R Windhager, C Chiari
Acute haematogenous osteomyelitis (AHO) in children is a severe condition. A delay in diagnosis and insufficient treatment may result in deformities, chronicity and sepsis. Therefore a structured diagnostic workup has to be followed in order to diagnose or rule out osteomyelitis. To identify the causative agent for targeted antibiotic treatment, a bone biopsy or puncture should be performed. However, approximately 25% of cases are culture-negative even after biopsy. The knowledge of the typical age-dependent bacterial spectrum is essential for empirical antibiotic therapy...
May 22, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28528870/recurrent-multifocal-osteomyelitis-in-children-experience-in-a-tertiary-care-center
#7
Ana Belén Ariza Jiménez, Esmeralda Núñez Cuadros, Rocío Galindo Zavala, Leticia Núñez Caro, Gisela Díaz-Cordobés Rego, Antonio Urda Cardona
INTRODUCTION: Chronic recurrent multifocal osteomyelitis is a rare aseptic bone inflammation that affects pediatric patients. Its management and treatment have not yet been standardized. METHODS: Retrospective, descriptive study of patients under 14 years of age diagnosed with chronic nonbacterial osteomyelitis (CNBO) in a tertiary hospital. We included patients diagnosed over the last 6 years (2010-2015) who met the Jansson criteria. The clinical and radiological characteristics of CNBO were analyzed, as was the outcome after different therapeutic options...
May 19, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28514223/hematogenous-osteomyelitis-in-infants-and-children-imaging-of-a-changing-disease
#8
REVIEW
Diego Jaramillo, John P Dormans, Jorge Delgado, Tal Laor, Joseph W St Geme
In children, hematogenous osteomyelitis is an infection that primarily affects the most vascularized regions of the growing skeleton. The disease has increased in frequency, virulence, and degree of soft-tissue involvement. The change in clinical manifestations and management over the past 2 decades should be reflected in the current imaging approach to the disease. Imaging of infection must depict the location of a single focus or of multiple foci of involvement and the presence of drainable collections. This review provides an overview of the imaging implications directed by the changing epidemiology, the newer insights of anatomy and pathophysiology, the imaging characteristics with emphasis on specific locations and disease complications, and the differential diagnosis considerations...
June 2017: Radiology
https://www.readbyqxmd.com/read/28507977/a-sub-acute-septic-arthritis-of-the-knee-a-sequelae-to-thorn-prick-injury-of-patella-a-case-report
#9
R Sivakumar, Prahalad Kumar Singhi, M Chidambaram, V Somashekar, Vinoth Thangamani
INTRODUCTION: Sub-acute septic arthritis of knee following a thorn prick injury to patella is an uncommon condition and seen in active playful children. The child may be afraid to narrate the incident to their parents or examining doctor, so a high index of suspicion is must. The delayed presentation is inevitable. Early synovitis due to the organic biological foreign body may progress to septic arthritis, if untreated may result in knee stiffness or chronic osteomyelitis of patella. CASE REPORT: We report a case of thorn prick injury to the left patella in an 8-years-old boy who neglected the incident of thorn prick while playing with his peer group 10 days ago and presented with features of sub-acute septic arthritis...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28491221/isolated-tuberculosis-of-metacarpal-bone-in-a-3-year-old-child
#10
El Mouhtadi Aghoutane, Tarik Salama, Redouane El Fezazi
Primary tuberculosis osteomyelitis of metacarpal bone is rare. The majority of cases occur in children and young adults and there is difficulty in diagnosis mainly in young children. We report a new case in children aged of 3 years, presenting a swelling on the dorsal side of her right hand since 8 months. X-ray showed an expansile, cystic and lytic lesion involving the little finger metacarpal. Tuberculosis was confirmed on histological examination. No lesions in lung parenchyma or lymphadenopathy were associated...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28486628/chronic-recurrent-multifocal-osteomyelitis-in-children-and-adults-current-understanding-and-areas-for-development
#11
Marion R Roderick, Ethan S Sen, Athimalaipet V Ramanan
Since the first descriptions of chronic recurrent multifocal osteomyelitis in the 1970s, there have been numerous case reports in the literature; both unusual case reports and case series from all over the world. Our understanding of the pathogenesis has significantly changed, with it now being regarded as an autoinflammatory condition. Treatment options have also expanded, but little progress has been made in developing the evidence for treatments. Advancing gene studies have provided a mouse model, but the quest for a single gene to match the phenotype has been elusive...
April 6, 2017: Rheumatology
https://www.readbyqxmd.com/read/28484657/osteomyelitis-of-the-patella-in-a-10-year-old-girl-a-case-report-and-review-of-the-literature
#12
Matthias Sperl, Michael Novak, Daniela Sperl, Martin Svehlik, Georg Singer, Tanja Kraus
The incidence of osteomyelitis constantly declines. While the disease most commonly affects the long bones, involvement of the patella is rarely seen. Due to this rarity and the variable clinical presentation, diagnosis is often delayed. The present case report describes a 10-year-old female patient with a delayed diagnosis of patella osteomyelitis. The diagnostic procedures and the treatment regimen are described. Additionally, a detailed literature review of the available publications reporting osteomyelitis of the patella in children is presented...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28477437/national-epidemiological-study-reveals-longer-paediatric-bone-and-joint-infection-stays-for-infants-and-in-general-hospitals
#13
E Laurent, L Petit, Z Maakaroun-Vermesse, L Bernard, T Odent, L Grammatico-Guillon
AIM: Published studies have suggested that 2-5 days of intravenous treatment could effectively treat paediatric bone and joint infections (PBJI), allowing a faster discharge. This study analysed the factors associated with PBJI hospital stays lasting longer than five days using the French National Hospital Discharge Database. METHODS: We selected children under 15 years hospitalised in 2013 with haematogenous PBJIs using a validated French algorithm based on specific diagnosis and surgical procedure codes...
May 6, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28471400/epidemiology-and-management-of-acute-haematogenous-osteomyelitis-in-a-tertiary-paediatric-center
#14
Elena Chiappini, Caterina Camposampiero, Simone Lazzeri, Giuseppe Indolfi, Maurizio De Martino, Luisa Galli
Background: Paediatric acute hematogenous osteomyelitis (AHOM) is a serious disease requiring early diagnosis and treatment. To review the clinical presentation, management and organisms responsible for AHOM, and to explore risk factors for complicated AHOM, a large cohort referring to a single center over a 6-year period was evaluated. Methods: Data from children with AHOM, hospitalized between 2010 and 2015, and aged > 1 month, were retrospectively collected and analyzed. Results: 121 children (median age 4...
May 4, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28461645/treatment-response-and-longterm-outcomes-in-children-with-chronic-nonbacterial-osteomyelitis
#15
Anja Schnabel, Ursula Range, Gabriele Hahn, Reinhard Berner, Christian M Hedrich
OBJECTIVE: The autoinflammatory bone disorder chronic nonbacterial osteomyelitis (CNO) covers a wide clinical spectrum, ranging from mild self-limited presentations to chronically active or recurrent courses, which are then referred to as chronic recurrent multifocal osteomyelitis (CRMO). Little is known about treatment options and longterm outcomes. We investigated treatment responses and outcomes in children with CNO. METHODS: A retrospective chart review was conducted in a tertiary referral center, covering 2004-2015...
May 1, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28450986/-major-sickle-cell-syndromes-and-infections-associated-with-this-condition-in-children-in-burkina-faso
#16
Sonia Douamba, Kisito Nagalo, Laure Tamini, Ismaël Traoré, Madibèlè Kam, Fla Kouéta, Diarra Yé
INTRODUCTION: This study aims to investigate infections in children with major sickle cell syndrome. METHODS: We conducted a monocentric descriptive retrospective hospital study in Ouagadougou, Burkina Faso, over a ten-year period. All children with major sickle cell syndrome (homozygous SS and double heterozygous SC, SDPunjab, Sβ thalassemic, SOArab and SE) hospitalized for microbiologically confirmed infections were enrolled in the study. RESULTS: One hundred and thirty-three patients met our inclusion criteria...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28419275/clinical-care-guideline-for-improving-pediatric-acute-musculoskeletal-infection-outcomes
#17
Murray D Spruiell, Justin Benjamin Searns, Travis C Heare, Jesse L Roberts, Erin Wylie, Laura Pyle, Nathan Donaldson, Jaime R Stewart, Heather Heizer, Jennifer Reese, Halden F Scott, Kelly Pearce, Colin J Anderson, Mark Erickson, Sarah K Parker
Background.: Acute pediatric musculoskeletal infections are common, leading to significant use of resources and antimicrobial exposure. In order to decrease variability and improve the quality of care, Children's Hospital Colorado implemented a clinical care guideline (CCG) for these infections. The purpose of this study is to evaluate clinical and resource outcomes PRE and POST this CCG. Methods.: Retrospective chart review evaluated patients admitted to a large pediatric quaternary referral center (CHCO) diagnosed with acute osteomyelitis, septic arthritis, pyomyositis, and/or musculoskeletal abscess prior to and after guideline implementation...
April 17, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/28417857/nuclear-medicine-imaging-in-pediatric-infection-or-chronic-inflammatory-diseases
#18
REVIEW
Alberto Signore, Andor W J M Glaudemans, Olivier Gheysens, Chiara Lauri, Onofrio A Catalano
In this review article, we focus on the most recent applications of nuclear medicine techniques (mainly (99m)Tc/(111)In white blood cells (WBC) scan, [(18)F]-FDG-PET/CT, [(18)F]-FDG-PET/MRI, and (99m)Tc-IL-2 scintigraphy) in the study of children affected by peripheral bone osteomyelitis, fungal infections, inflammatory bowel diseases, and type 1 diabetes, owing to recent important published evidences of their role in the management of these diseases. For osteomyelitis in children, both bone scintigraphy and [(18)F]-FDG-PET have a major advantage of assessing the whole body in one imaging session to confirm or exclude multifocal involvement, whereas WBC scan has a limited role...
May 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28417851/nuclear-medicine-techniques-in-pediatric-bone-imaging
#19
REVIEW
Laura A Drubach
An important mandate when imaging pediatric patients is the reduction of radiation exposure to the lowest possible level consistent with good quality diagnostic imaging, so individual selection of radiopharmaceutical dosage and imaging technique is essential. Although the logistics of image acquisition and the approach to interpretation mirror the more common use in adults, the challenges of imaging young children typically require greater attention to patient preparation, positioning, and supervision during imaging, with the use of parental or family engagement in the procedure, gentle restraint, and occasionally the need for sedation...
May 2017: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/28410697/multifocal-pure-tubercular-osteomyelitis-an-unusual-presentation-in-childhood
#20
Sananda Pati, Sangita De, Tarak Nath Ghosh, Mrinal Kanti Ghosh
Tuberculosis is a major health problem in the developing world. One-third of children infected with Mycobacterium tuberculosis have extra pulmonary involvement. Skeletal tuberculosis occurs in 1-6% of them with vertebra being the commonest site. Pure tubercular osteomyelitis without joint involvement occurs in only 2-3% cases of osteoarticular tuberculosis. Common sites are femur, tibia, and fibula. Disseminated skeletal involvement is very rare in children (7%) and calvarial osteomyelitis is even rarer (1%)...
April 2017: Indian Journal of Tuberculosis
keyword
keyword
112099
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"