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https://www.readbyqxmd.com/read/28636255/recombinant-human-serum-albumin-for-corneal-preservation
#1
Mohit Parekh, Hossein Elbadawy, Gianni Salvalaio, Marie-Claude Amoureux, Enzo Di Iorio, Denis Fortier, Diego Ponzin, Stefano Ferrari, Alessandro Ruzza
PURPOSE: To study the performance of a completely synthetic organ culture (OC) preservation system containing recombinant human serum albumin (rHSA) for preservation of human donor corneas. METHODS: Twenty-four paired donor corneas were randomly collected, and one cornea from each donor was preserved in synthetic (experimental) and serum-based media (control). The tissues were assessed at day 0; after 6 days of preservation at room temperature (RT) in Cornea Trans(®) and Cornea Prep II(®) ; after 28 days at 31°C in Cornea Syn(®) [with rHSA] and Cornea Max(®) [with foetal calf serum (FCS)] and; 4-day post deswelling in Cornea Trans(®) and Cornea Jet(®) ...
June 21, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28635362/costs-and-effectiveness-of-fingolimod-versus-alemtuzumab-in-the-treatment-of-highly-active-relapsing-remitting-multiple-sclerosis-in-the-uk-retreatment-discount-and-disutility
#2
Stephen M Montgomery, Jeanette Kusel, Richard Nicholas, Nicholas Adlard
OBJECTIVE: Patients with relapsing-remitting multiple sclerosis (RRMS) treated with disease modifying therapies (DMTs) who continue to experience disease activity may be considered for escalation therapies such as fingolimod or may be considered for alemtuzumab. Previous economic modelling used Markov models; applying one alternative technique, discrete event simulation (DES) modelling, allows retreatment and long-term adverse events (AEs) to be included in the analysis. METHODS: A DES was adapted to model relapse-triggered retreatment with alemtuzumab and the effect of including ongoing quality-adjusted life year (QALY) decrements for AEs that extend beyond previous one year Markov cycles...
June 21, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28635345/avatar-assisted-therapy-a-proof-of-concept-pilot-study-of-a-novel-technology-based-intervention-to-treat-substance-use-disorders
#3
Michael S Gordon, Steven B Carswell, Mary Schadegg, Kayla Mangen, Kelly Merkel, Susan Tangires, Frank J Vocci
BACKGROUND: Avatar-assisted therapy (AAT) is a novel and emerging technology that uses the Internet to enable clinicians and clients in substance abuse treatment to participate in group counseling sessions from separate and remote locations in real time through the use of avatars and virtual environments. OBJECTIVES: The current study is a pilot proof-of-concept feasibility study involving individuals in outpatient substance abuse treatment. This report addresses two questions: (1) are individuals who present for substance abuse treatment interested in receiving AAT and (2) what factors are associated with better treatment success...
February 17, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28619682/air-quality-and-acute-deaths-in-california-2000-2012
#4
S Stanley Young, Richard L Smith, Keneth K Lopiano
Many studies have shown an association between air quality and acute deaths, and such associations are widely interpreted as causal. Several factors call causation and even association into question, for example multiple testing and multiple modeling, publication bias and confirmation bias. Many published studies are difficult or impossible to reproduce because of lack of access to confidential data sources. Here we make publically available a dataset containing daily air quality levels, PM2.5 and ozone, daily temperature levels, minimum and maximum and daily maximum relative humidity levels for the eight most populous California air basins, thirteen years, >2M deaths, over 37,000 exposure days...
June 12, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28618008/needs-and-challenges-of-home-visitors-conducting-perinatal-depression-screening
#5
Jennifer J Doering, Kristyn Maletta, Audrey Laszewski, Christina L Wichman, Jennifer Hammel
This article describes the needs and challenges faced by home visitors, supervisors, and clients when conducting perinatal depression screening. Home visitors (n = 11), supervisors (n = 5), and clients (n = 9) representing rural and urban practice settings in Wisconsin were recruited into three separate focus groups. Themes were identified from the transcribed audio-recorded interviews using content analysis. Results indicate that a trusting relationship was leveraged to facilitate depression screening and referral...
June 15, 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28616415/quality-evaluation-of-persian-nutrition-and-diet-therapy-websites
#6
Zahra Gholizadeh, Ahmad Papi, Hasan Ashrafi-Rizi, Leila Shahrzadi, Akbar Hasanzadeh
INTRODUCTION: Nowadays websites are among the most important information sources used by most people. With the spread of websites, especially those related to health issues, the number of their visitors also increases, more than half of which are about nutritional information. Therefore, quality analysis of nutrition and diet therapy websites is of outmost importance. This study aims to evaluate the quality of Persian nutrition and diet therapy websites. METHODS: The current work is a survey study and uses an applied study method...
2017: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/28615181/fifteen-minute-consultation-communicating-with-young-people-how-to-use-heeadsss-a-psychosocial-interview-for-adolescents
#7
Montserrat Doukrou, Terry Yvonne Segal
Adolescents undergo a period of biological, social and psychosocial development, and each of these domains impacts each other. Psychosocial areas of concern often emerge over the adolescent period (such as mental health conditions, drug use and risky sexual behaviour); those with chronic illness being at higher risk. The paper aims to guide health practitioners on when and how to approach the psychosocial interview with young people and assess areas of risk or concern. This will include putting them at ease, developing rapport, seeing them alone and explaining confidentiality before commencing the assessment...
June 14, 2017: Archives of Disease in Childhood. Education and Practice Edition
https://www.readbyqxmd.com/read/28612650/pediatric-nurses-ethical-difficulties-in-the-bedside-care-of-children
#8
Kwisoon Choe, Yoonjung Kim, Yoonseo Yang
BACKGROUND: Pediatric nurses experience ethically difficult situations in their everyday work. Several studies have been conducted to reveal ethical issues among pediatric nurses; we do not think their ethical difficulties have been explored sufficiently from their own perspective. OBJECTIVES: This study aimed to explore the ethical difficulties faced by pediatric nurses during bedside care for hospitalized children. METHODS: A phenomenological approach was used to collect and analyze interview data from 14 female pediatric nurses in South Korea...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28612545/-pharmacokinetics-of-curcumin-ethosomes-in-rats-in-vitro
#9
Jing Zhao, Yuan Li, Ming-Xin Shi, Xue Wang, Jing-Qing Zhang
OBJECTIVES: To study the oral phamacokinetics of curcumin ethosomes in rats. METHODS: Pharmacokinetics parameters were detected by DAS 2.1.1 software analysis through data of blood concentrations harvested from HPLC after oral administration of curcumin ethosomes in rats. RESULTS: Analyzed by non-compartmental method, the area under concentration-time curve from 0 to last time [AUC(0-72h)] of curcumin ethosomes was 1.6 times larger than that of free curcumin, the peak concentration (C max) of curcumin ethosomes was 1...
March 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28612480/adolescent-narrative-comments-in-assessing-medical-students
#10
April Tan, Alexandra Hudson, Kim Blake
BACKGROUND: Adolescent medical interviewing is a difficult topic to teach and assess. Programmatic assessment has been gaining interest in medical teaching, and shifts the mode of assessment from the traditional assessment of learning (e.g. written exams) to the assessment for learning (e.g. feedback). The Structured Communication Adolescent Guide (SCAG) is a programmatic assessment tool that allows an adolescent patient to provide three types of feedback (written, numeric, grade) to a medical student in an authentic clinical workplace...
June 14, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/28611187/comparing-outcomes-of-coronary-artery-bypass-grafting-among-large-teaching-and-urban-hospitals-in-china-and-the-united-states
#11
Zhe Zheng, Heng Zhang, Xin Yuan, Chenfei Rao, Yan Zhao, Yun Wang, Sharon-Lise Normand, Harlan M Krumholz, Shengshou Hu
BACKGROUND: Coronary artery disease is prevalent in China, with concomitant increases in the volume of coronary artery bypass grafting (CABG). The present study aims to compare CABG-related outcomes between China and the United States among large teaching and urban hospitals. METHODS AND RESULTS: Observational analysis of patients aged ≥18 years, discharged from acute-care, large teaching and urban hospitals in China and the United States after hospitalization for an isolated CABG surgery...
June 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28611111/the-impact-of-interventions-to-improve-the-quality-of-prescribing-and-use-of-antibiotics-in-primary-care-patients-with-respiratory-tract-infections-a-systematic-review-protocol
#12
Nahara Anani Martínez-González, Samuel Coenen, Andreas Plate, Annelies Colliers, Thomas Rosemann, Oliver Senn, Stefan Neuner-Jehle
INTRODUCTION: Respiratory tract infections (RTIs) are the most common reason for primary care (PC) consultations and for antibiotic prescribing and use. The majority of RTIs have a viral aetiology however, and antibiotic consumption is ineffective and unnecessary. Inappropriate antibiotic use contributes greatly to antibiotic resistance (ABR) leading to complications, increased adverse events, reconsultations and costs. Improving antibiotic consumption is thus crucial to containing ABR, which has become an urgent priority worldwide...
June 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28611110/the-liftmor-m-lifting-intervention-for-training-muscle-and-osteoporosis-rehabilitation-for-men-trial-protocol-for-a-semirandomised-controlled-trial-of-supervised-targeted-exercise-to-reduce-risk-of-osteoporotic-fracture-in-older-men-with-low-bone-mass
#13
Amy T Harding, Benjamin K Weeks, Steven L Watson, Belinda R Beck
INTRODUCTION: The primary aim of the proposed study is to examine the efficacy of an 8-month supervised, high-intensity progressive resistance training and impact loading programme in comparison with a supervised machine-based isometric exercise training programme using the bioDensity system in older men with low bone mass. We will also determine the safety and acceptability of each exercise training mode. Intervention group responses will be compared with those of a self-selected, non-randomised control sample of sex-matched and age-matched men who will follow their usual lifestyle activities for 8 months...
June 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28610531/keep-handovers-in-the-office
#14
Louise Richards
Patient information is meant to be confidential. How is that possible when you give a bedside handover with other patients in the room (Readers' Panel, June 7). Handovers should be done in the office, followed by a walk around to introduce yourself as the nurse taking over the care, and to check on any infusions.
June 14, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28609723/a-rural-urban-comparison-of-privacy-and-confidentiality-concerns-associated-with-providing-sensitive-location-information-in-epidemiologic-research-involving-persons-who-use-drugs
#15
Abby E Rudolph, April M Young, Jennifer R Havens
BACKGROUND: Analyses that link contextual factors with individual-level data can improve our understanding of the "risk environment"; however, the accuracy of information provided by participants about locations where illegal/stigmatized behaviors occur may be influenced by privacy/confidentiality concerns that may vary by setting and/or data collection approach. METHODS: We recruited thirty-five persons who use drugs from a rural Appalachian town and a Mid-Atlantic city to participate in in-depth interviews...
June 8, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28604628/privacy-preserving-electrocardiogram-monitoring-for-intelligent-arrhythmia-detection
#16
Junggab Son, Juyoung Park, Heekuck Oh, Md Zakirul Alam Bhuiyan, Junbeom Hur, Kyungtae Kang
Long-term electrocardiogram (ECG) monitoring, as a representative application of cyber-physical systems, facilitates the early detection of arrhythmia. A considerable number of previous studies has explored monitoring techniques and the automated analysis of sensing data. However, ensuring patient privacy or confidentiality has not been a primary concern in ECG monitoring. First, we propose an intelligent heart monitoring system, which involves a patient-worn ECG sensor (e.g., a smartphone) and a remote monitoring station, as well as a decision support server that interconnects these components...
June 12, 2017: Sensors
https://www.readbyqxmd.com/read/28604306/andreas-holger-maehle-contesting-medical-confidentiality-origins-of-the-debate-in-the-united-states-britain-and-germany-chicago-il-and-london-university-of-chicago-press-2016-pp-%C3%A2-168-40-00-hardback-isbn-%C3%A2-978-0-226-40482-0
#17
https://www.readbyqxmd.com/read/28599816/delivering-healthcare-at-a-distance-exploring-the-organisation-of-calls-to-a-health-helpline
#18
Stefanie Lopriore, Amanda LeCouteur, Stuart Ekberg, Katie Ekberg
BACKGROUND: Health helplines are integral to contemporary healthcare, offering fast, low-cost, and geographically unrestricted access to health information and advice. Although some health helplines offer support services (e.g., counselling), many function in ways that are similar to physically co-present (i.e., face-to-face) primary care consultations. However, due to the lack of physical presence, there are differences in the way health consultations are routinely managed on the telephone...
August 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28598801/improving-adolescent-access-and-services-in-a-large-primary-care-network-report-of-a-10-year-project
#19
Elizabeth M Alderman, Kim L Freeman, Katherine S Lobach
This report describes a decade long initiative to bring a unified approach and improved quality to the process and content of adolescent health care in a large and complex urban primary care network within an academic health system. The moving force was a voluntary multidisciplinary group who comprised the Montefiore Adolescent Primary Care Initiative, known as MAPCI, led by a physician subspecialist in Adolescent Medicine. A series of needs assessments formed the basis for a multipronged effort to create policies and procedures, educational activities and materials, changes in record-keeping and billing practices, and modification of staff attitudes and behavior that would enhance access and ensure confidentiality of services for the adolescent age group...
June 9, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28595734/ethics-big-data-and-computing-in-epidemiology-and-public-health
#20
Jennifer Salerno, Bartha M Knoppers, Lisa M Lee, WayWay M Hlaing, Kenneth W Goodman
PURPOSE: This article reflects on the activities of the Ethics Committee of the American College of Epidemiology (ACE). Members of the Ethics Committee identified an opportunity to elaborate on knowledge gained since the inception of the original Ethics Guidelines published by the ACE Ethics and Standards of Practice Committee in 2000. METHODS: The ACE Ethics Committee presented a symposium session at the 2016 Epidemiology Congress of the Americas in Miami on the evolving complexities of ethics and epidemiology as it pertains to "big data...
May 2017: Annals of Epidemiology
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