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https://www.readbyqxmd.com/read/28930372/efficacy-and-safety-of-blood-transfusion-in-obstetric-patients-systematic-review-of-the-literature
#1
Celso Módolo, Arnav Agarwal, Mariana Floriano Luiza Piva, Andresa Graciutti Botan, Samira Esteves Afonso Camargo, Nermeen Gawish, Norma Sueli Pinheiro Módolo, Regina El Dib
OBJECTIVES: To evaluate the efficacy of blood transfusion compared to no intervention in obstetric patients. MATERIAL AND METHODS: A systematic review was performed with Cochrane Database of Clinical Trials, PubMed, EMBASE and LILACS databases searched as of September, 2016. Two authors independently selected relevant clinical trials, assessed their methodological quality and extracted data, using the GRADE approach. RESULTS: Five studies within a total of 6,297 met the inclusion criteria, with women generally aged 20-40 years...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28930296/the-verified-neighbor-approach-to-geoprivacy-an-improved-method-for-geographic-masking
#2
Wayne Richter
Geographic information adds a powerful component to environmental epidemiology studies but can compromise subject confidentiality. Although locations are often masked by perturbing spatial coordinates, existing masks do not ensure that the perturbation area contains a sufficient number of valid surrogates to prevent disclosure, nor are they designed to minimize perturbation while maintaining a specified level of privacy. I introduce a new approach to geoprivacy in which real property parcel data with information about land use are used to develop a pool of verified neighbors...
September 20, 2017: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/28929860/adolescent-perspectives-on-patient-provider-sexual-health-communication-a-qualitative-study
#3
Andrea J Hoopes, Samantha K Benson, Heather B Howard, Diane M Morrison, Linda K Ko, Taraneh Shafii
BACKGROUND: Adolescents in the United States are disproportionately affected by sexually transmitted infections and unintended pregnancy. Adolescent-centered health services may reduce barriers to health care; yet, limited research has focused on adolescents' own perspectives on patient-provider communication during a sexual health visit. METHODS: Twenty-four adolescents (14-19 years old) seeking care in a public health clinic in Washington State participated in one-on-one qualitative interviews...
September 1, 2017: Journal of Primary Care & Community Health
https://www.readbyqxmd.com/read/28928897/identification-of-nucleobindin-2-as-a-potential-biomarker-for-breast-cancer-metastasis-using-itraq-based-quantitative-proteomic-analysis
#4
Liang Zeng, Jingmin Zhong, Guangchun He, Fangjun Li, Jing Li, Wen Zhou, Wenbin Liu, Yun Zhang, Sanqian Huang, Zhihong Liu, Xiyun Deng
Metastasis is a lethal step in the progression of breast cancer. None of the metastasis-associated biomarkers identified up to now has a definite prognostic value in breast cancer patients. This study was designed to identify biomarkers for breast cancer metastasis and predictors of the prognosis of breast cancer patients. The differentially expressed proteins between 23 paired primary breast tumor and metastatic lymph nodes were identified by quantitative iTRAQ proteomic analysis. Immunohistochemistry was applied to locate and assess the expression of NUCB2 in paired primary breast tumor and metastatic lymph node tissues (n = 106)...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28921556/dating-and-sexual-violence-research-in-the-schools-balancing-protection-of-confidentiality-with-supporting-the-welfare-of-survivors
#5
Jill D Sharkey, Lauren A Reed, Erika D Felix
Rigorous research and program evaluation are needed to understand the experience of dating and sexual violence among youth and the impact of prevention and intervention efforts. Our dilemma in doing this work occurred when youth disclosed dating and sexual violence on a research survey. What responsibility do researchers have to protect survivors' confidentiality as a research participant versus taking steps to ensure the student has the opportunity to access help? In our evaluation of a pilot dating violence prevention program, our protocols employed widely used procedures for providing resources to participants upon their completion of the survey and de-identifying survey data...
September 18, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28919720/text-messaging-to-decrease-tuberculosis-treatment-attrition-in-tb-hiv-coinfection-in-uganda
#6
Sabine M Hermans, Sawsan Elbireer, Harriet Tibakabikoba, Bas J Hoefman, Yukari C Manabe
BACKGROUND: Low tuberculosis (TB) treatment completion rates in sub-Saharan Africa are an important driver of multidrug resistance. Mobile technology-based interventions have been shown to improve adherence to antiretroviral therapy in sub-Saharan Africa. We aimed to test the effect of a short-message service (SMS) intervention on loss to follow-up (LFU). MATERIALS AND METHODS: In this quasi-experimental study, all adult, literate, HIV-infected patients with mobile phone access diagnosed with TB between November 2010 and October 2011 in an urban clinic in Uganda were eligible to receive adherence and appointment reminders and educational quizzes during the first 8 weeks of TB treatment...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28918379/infanrix-hexa-and-sudden-death-a-review-of-the-periodic-safety-update-reports-submitted-to-the-european-medicines-agency
#7
Jacob Puliyel, C Sathyamala
There have been a number of spontaneous reports of sudden unexpected death soon after the administration of Infanrix hexa (combined diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliomyelitis and Haemophilus influenza type B vaccine). The manufacturer, GlaxoSmithKline (GSK), submits confidential periodic safety update reports (PSURs) on Infanrix hexa to the European Medicines Agency (EMA). The latest is the PSUR 19. Each PSUR contains an analysis of observed/expected sudden deaths, which shows that the number of observed deaths soon after immunisation is lower than that expected by chance...
September 5, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28917371/cannabinoids-for-spasticity-due-to-multiple-sclerosis-or-paraplegia-a-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#8
REVIEW
Victoria P da Rovare, Gabriel P A Magalhães, Guilherme D A Jardini, Matheus L Beraldo, Mariel O Gameiro, Arnav Agarwal, Gustavo José Luvizutto, Lucas Paula-Ramos, Samira Esteves Afonso Camargo, Luciane Dias de Oliveira, Rodrigo Bazan, Regina El Dib
OBJECTIVES: Spasticity remains highly prevalent in patients with spinal cord injury and multiple sclerosis. To summarize the effects of cannabinoids compared with usual care, placebo for spasticity due to multiple sclerosis (MS) or paraplegia. METHODS: Searches of MEDLINE, EMBASE, CENTRAL and LILACS to March 2017 were performed to identify randomized controlled trials. The primary outcomes were spasticity and spasm frequency. The criteria were any patient with MS and spasticity affecting upper or lower limbs or both, and that had a confirmed diagnosis of MS based on validated criteria, or however defined by the authors of the included studies...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28916453/making-the-legal-and-ethical-case-for-universal-screening-for-postpartum-mood-and-anxiety-disorders-in-pediatric-primary-care
#9
Amy Lewis Gilbert, Casey Balio, Nerissa S Bauer
Postpartum depression (PPD), part of a larger spectrum of perinatal mood and anxiety disorders, affects up to 15% of women following the birth of an infant. Fathers may also be affected. PPD not only affects caregivers, but also impacts infants through mechanisms such as inadequate caregiver-infant interactions and non-adherence to safety practices. The negative impact on infants may extend across the life course through adulthood. This article seeks to move the needle toward universal screening for PPD using validated tools in pediatric primary care settings for new caregivers by making the legal and ethical case for this course of action in a manner that is both compelling and accessible for clinicians...
September 12, 2017: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/28915696/top2a-ggh-and-pecam1-are-associated-with-hematogenous-lymph-node-and-peritoneal-recurrence-in-stage-ii-iii-gastric-cancer-patients-enrolled-in-the-acts-gc-study
#10
Masanori Terashima, Wataru Ichikawa, Atsushi Ochiai, Koji Kitada, Issei Kurahashi, Shinichi Sakuramoto, Hitoshi Katai, Takeshi Sano, Hiroshi Imamura, Mitsuru Sasako
BACKGROUND: To identify factors related to relapse sites, we carried out an exploratory biomarker analysis of data from the Adjuvant Chemotherapy Trial of TS-1 for Gastric Cancer study, which is a randomized, controlled trial comparing postoperative adjuvant S-1 therapy with surgery alone in 1,059 patients with stage II/III gastric cancer. PATIENTS AND METHODS: Surgical specimens from 829 patients were retrospectively examined, and 63 genes involved in a variety of biological processes were analyzed by quantitative real-time PCR...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28915431/ethical-implications-of-location-and-accelerometer-measurement-in-health-research-studies-with-mobile-sensing-devices
#11
Daniel Fuller, Martine Shareck, Kevin Stanley
Quantification of individual behaviours using mobile sensing devices, including physical activity and spatial location, is a rapidly growing field in both academic research and the corporate world. In this case study, we summarize the literature examining the ethical aspects of mobile sensing and argue that a robust discussion about the ethical implications of mobile sensing for research purposes has not occurred sufficiently in the literature. Based on our literature summary and guided by basic ethical principles set out in Canadian, US, and International Ethics documents we propose four areas where further discussion should occur: consent, privacy and confidentiality, mitigating risk, and consideration of vulnerable populations...
September 12, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28915109/factors-affecting-utilization-of-youth-friendly-health-services-in-lagos-state-nigeria
#12
Toriola Temitope Femi-Adebayo, Yetunde Kuyinu, Olusola Adedeji Adejumo, Olayinka Goodman
Background Youth friendly health services (YFHS) are services that attract, respond to the needs of and retain young people for continuing care. This study was conducted to determine the factors affecting utilization of government (GYFF) and non-governmental youth friendly facilities (NGYFF) in Lagos state, Nigeria. Methods A descriptive cross-sectional study was conducted. A total of 543 adolescents aged 15-24 years, between August 1, 2014 and October 31, 2014 were consecutively recruited from 10 (five government and five non-governmental) youth friendly health facilities that had been in operation for at least 6 months prior to the study...
September 15, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28905728/what-are-physicians-responsibilities-to-patients-whose-health-conditions-can-influence-their-legal-proceedings
#13
David Beckmann
Correctional populations are disproportionately affected by conditions that affect cognition, such as psychiatric illness and head trauma. Honoring bioethical principles in the care of such patients can be particularly difficult in the correctional setting. However, the approach should not change markedly because a patient is incarcerated. That is, the same standards of respecting patient autonomy and confidentiality should be maintained, and the fact that correctional populations are already marginalized makes it all the more important for clinicians to honor these principles...
September 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28905258/is-biomedical-research-protected-from-predatory-reviewers
#14
Aceil Al-Khatib, Jaime A Teixeira da Silva
Authors endure considerable hardship carrying out biomedical research, from generating ideas to completing their manuscripts and submitting their findings and data (as is increasingly required) to a journal. When researchers submit to journals, they entrust their findings and ideas to editors and peer reviewers who are expected to respect the confidentiality of peer review. Inherent trust in peer review is built on the ethical conduct of authors, editors and reviewers, and on the respect of this confidentiality...
September 13, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28903839/comparison-of-cognitive-professionalism-in-residents-of-public-and-private-hospitals-of-karachi
#15
Nighat Shah, Masood Javed, Nusrat Shah, Mariam Soomro
OBJECTIVE: To evaluate and compare the cognitive professionalism in resident medical officers (RMOs) of public and private hospitals of Karachi. STUDY DESIGN: Across-sectional survey. PLACE AND DURATION OF STUDY: Civil Hospital and Ziauddin Medical University Clifton Campus, Karachi, from August to December 2014. METHODOLOGY: This survey was conducted in one public and one private medical college. All residents from Gynecology and Obstetrics, Medicine and Surgery departments were included with non-probability purposive sampling...
August 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28903594/book-review-confidentiality-and-its-discontents-dilemmas-of-privacy-in-psychotherapy-confidentiality-and-its-discontents-dilemmas-of-privacy-in-psychotherapy-by-mosher-paul-w-berman-jeffrey-new-york-fordham-university-press-2015-xiv-343-pp-125-00-hardcover
#16
https://www.readbyqxmd.com/read/28903081/ethical-practices-in-community-based-research-in-non-suicidal-self-injury-a-systematic-review
#17
REVIEW
Nupur Singhal, Poornima Bhola
BACKGROUND: The growing interest in community-based research on non-suicidal self-injury (NSSI) reflects the high prevalence rates found among vulnerable adolescents and young adults. A significant concern in research with vulnerable populations, and on sensitive topics, is the development of an ethical framework that protects the needs and rights of the participants while responding to researchers' goals and limitations and the broader clinical and public health concerns. AIM: The aim of the present study was to review the ethical practices followed in community-based research on NSSI...
September 1, 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28900790/medical-images-are-safe-an-enhanced-chaotic-scrambling-approach
#18
M Y Mohamed Parvees, J Abdul Samath, B Parameswaran Bose
The patient data confidentiality is one of the vital security aspects in e-Health and m-Health services. In particular, providing confidentiality to the patient's medical image is essential and the protection approaches have to be explored in-depth due to the rapid progress in the technologies of teleradiology and PACS. In this study, the pseudo random number generators (PRNGs), namely, the linear congruential generator (LCG) and XOR shift generator (XSG) are improved and combined with improved logistic 2D coupled chaotic map to provide enhanced chaos based encryption...
September 12, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28898327/-transition-from-pediatric-to-adult-health-care-services-for-adolescents-with-chronic-diseases-recommendations-from-the-adolescent-branch-from-sociedad-chilena-de-pediatr%C3%A3-a
#19
Tamara Zubarew, Loreto Correa, Paula Bedregal, Carolina Besoain, Alejandro Reinoso, Macarena Velarde, María Teresa Valenzuela, Carolina Inostroza
The Adolescent Branch from Sociedad Chilena de Pediatría supports the implementation of planned programs for transition from child to adult health centers, oriented to adolescents with chronic diseases, in order to ensure an appropriate follow-up and a high-quality health care. Recommendations for care are set out in the FONIS and VRI PUC project carried out by the Division of Pediatrics of the Universidad Católica de Chile: “Transition process from pediatric to adult services: perspectives of adolescents with chronic diseases, caregivers and health professionals”, whose goal was to describe the experience, barriers, critical points, and facilitators in the transition process...
2017: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/28898156/inspiring-change-a-report-on-acute-non-invasive-ventilation
#20
M C Juniper, G Ellis, K L Protopapa, Nce Smith
The British Thoracic Society audit of non-invasive ventilation has shown that mortality rates are higher than expected and increasing. The National Confidential Enquiry into Patient Outcome and Death undertook a detailed analysis of data from 432 patients treated with acute non-invasive ventilation to identify how clinical aspects of non-invasive ventilation treatment could be improved. The study 'Inspiring Change' was published in July 2017. This review summarizes some of the important findings and associated recommendations that will improve treatment of patients and help to reduce mortality rates...
September 2, 2017: British Journal of Hospital Medicine
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