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https://www.readbyqxmd.com/read/28732067/thromboembolic-adverse-event-study-of-combined-estrogen-progestin-preparations-using-japanese-adverse-drug-event-report-database
#1
Shiori Hasegawa, Toshinobu Matsui, Yuuki Hane, Junko Abe, Haruna Hatahira, Yumi Motooka, Sayaka Sasaoka, Akiho Fukuda, Misa Naganuma, Kouseki Hirade, Yukiko Takahashi, Yasutomi Kinosada, Mitsuhiro Nakamura
Combined estrogen-progestin preparations (CEPs) are associated with thromboembolic (TE) side effects. The aim of this study was to evaluate the incidence of TE using the Japanese Adverse Drug Event Report (JADER) database. Adverse events recorded from April 2004 to November 2014 in the JADER database were obtained from the Pharmaceuticals and Medical Devices Agency (PMDA) website (www.pmda.go.jp). We calculated the reporting odds ratios (RORs) of suspected CEPs, analyzed the time-to-onset profile, and assessed the hazard type using Weibull shape parameter (WSP)...
2017: PloS One
https://www.readbyqxmd.com/read/28731855/seeking-sexual-health-information-professionals-novel-experiences-of-the-barriers-that-prevent-female-adolescents-seeking-sexual-health-information
#2
Kerry McKellar, Linda Little, Michael A Smith, Elizabeth Sillence
Objective Sexual health professionals are key stakeholders in implementing sexual health intervention programmes, yet their views are largely absent from the literature. Sexual health professionals provide a unique perspective on teen sexual health issues as they engage in confidential discussions with a wide range of teenagers. This study aimed to provide an in-depth exploration of professionals' perceptions of teenagers' sexual health information seeking practices and barriers. Furthermore, the research provided a unique re-examination of key predictors of risky sexual behaviours, which have been highlighted by previous research...
July 21, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28727762/sexual-diversity-in-the-united-states-results-from-a-nationally-representative-probability-sample-of-adult-women-and-men
#3
Debby Herbenick, Jessamyn Bowling, Tsung-Chieh Jane Fu, Brian Dodge, Lucia Guerra-Reyes, Stephanie Sanders
In 2015, we conducted a cross-sectional, Internet-based, U.S. nationally representative probability survey of 2,021 adults (975 men, 1,046 women) focused on a broad range of sexual behaviors. Individuals invited to participate were from the GfK KnowledgePanel®. The survey was titled the 2015 Sexual Exploration in America Study and survey completion took about 12 to 15 minutes. The survey was confidential and the researchers never had access to respondents' identifiers. Respondents reported on demographic items, lifetime and recent sexual behaviors, and the appeal of 50+ sexual behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/28726059/professional-ethics-for-digital-age-psychiatry-boundaries-privacy-and-communication
#4
REVIEW
James E Sabin, Jonathan Clark Harland
PURPOSE OF REVIEW: Internet and social media use continue to expand rapidly. Many patients and psychiatrists are bringing digital technologies into the treatment process, but relatively little attention has been paid to the ethical challenges in doing this. This review presents ethical guidelines for psychiatry in the digital age. RECENT FINDINGS: Surveys demonstrate that patients are eager to make digital technologies part of their treatment. Substantial numbers search for professional and personal information about their therapists...
September 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28724142/the-aging-physician-and-the-medical-profession-a-review
#5
E Patchen Dellinger, Carlos A Pellegrini, Thomas H Gallagher
Importance: The issue of the aging physician and when to cease practice has been controversial for many years. There are reports of prominent physicians who practiced after becoming dangerous in old age, but the profession has not demonstrated the ability to prevent this. A mandatory retirement age could be discriminatory and take many competent physicians out of practice and risk a physician shortage. An increasing body of evidence regarding the relationship between physicians' age and performance has led organizations, such as the American College of Surgeons, to revisit this challenge...
July 19, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28723970/barriers-and-facilitators-of-hiv-vaccine-and-prevention-study-participation-among-young-black-msm-and-transwomen-in-new-york-city
#6
Sharise Richardson, Pich Seekaew, Beryl Koblin, Tasha Vazquez, Vijay Nandi, Hong-Van Tieu
BACKGROUND: Black men who have sex with men (MSM), and Transwomen (TW) shoulder disproportionate burden of HIV. However, they are unrepresented in HIV vaccine trials. We investigated the perceptions of that factors associated with HIV vaccine trials participation among Black MSM and TW in New York. METHODS: Self-administered online questionnaires were administered to 18-29 years of NYC residents who identified as Black MSM and TW, assessing demographics, awareness and willingness to participate in HIV vaccine trials, barriers and facilitators associated with willingness, and sexual behaviors...
2017: PloS One
https://www.readbyqxmd.com/read/28723309/moral-distress-as-experienced-by-hospital-social-workers-in-south-korea-and-australia
#7
Patricia Fronek, Lynne Briggs, Myung Hun Kim, Hye Bin Han, Quinn Val, Sungmin Kim, Donna McAuliffe
This exploratory, qualitative research explored the ethical problems faced by hospital social workers in South Korea and Australia, and what and who influenced their decision making using a focus group design. Although dilemmas of boundaries, confidentiality, self-determination, and other complex scenarios found in practice were identified, moral distress, a consequence of the unresolvable conflicts, dominated participants' narratives. This was particularly the case for the Korean social workers in this sample...
July 19, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28723087/developing-collaborative-qsar-models-without-sharing-structures
#8
Peter Gedeck, Suzanne Skolnik, Stephane Rodde
It is widely understood that QSAR models greatly improve if more data are used. However, irrespective of model quality, once chemical structures diverge too far from the initial data set, the predictive performance of a model degrades quickly. To increase the applicability domain we need to increase the diversity of the training set. This can be achieved by combining data from diverse sources. Public data can be easily included, however proprietary data may be more difficult to add due to intellectual property concerns...
July 19, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28722558/situating-mobile-health-a-qualitative-study-of-mhealth-expectations-in-the-rural-health-district-of-nouna-burkina-faso
#9
Vincent Duclos, Maurice Yé, Kagoné Moubassira, Hamidou Sanou, N Hélène Sawadogo, Gilles Bibeau, Ali Sié
BACKGROUND: The implementation of mobile health (mHealth) projects in low- and middle-income countries raises high and well-documented expectations among development agencies, policymakers and researchers. By contrast, the expectations of direct and indirect mHealth users are not often examined. In preparation for a proposed intervention in the Nouna Health District, in rural Burkina Faso, this study investigates the expected benefits, challenges and limitations associated with mHealth, approaching these expectations as a form of situated knowledge, inseparable from local conditions, practices and experiences...
July 12, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28721112/current-perspectives-in-the-usa-on-the-diagnosis-and-treatment-of-pelvic-inflammatory-disease-in-adolescents
#10
REVIEW
William L Risser, Jan M Risser, Amanda L Risser
In this review, the epidemiology, diagnosis, and treatment of pelvic inflammatory disease (PID) are discussed from a USA perspective and the difficulties that USA adolescents face in recognizing and seeking care for PID and other sexually transmitted infections (STIs) are emphasized. Females aged 15-24 years have the highest incidence of cervical infection with Chlamydia trachomatis and Neisseria gonorrheae, the principal causes of PID. PID is common in this age group. However, the incidence of PID in the USA is not known, because it is not a reportable disease, and because clinicians vary in the criteria used for the diagnosis...
2017: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/28719365/proposed-model-for-the-cultural-adaptation-of-an-internet-based-depression-prevention-intervention-catch-it-for-arab-adolescents
#11
Zach Abuwalla, Zaynab Kadhem, Tracy Gladstone, Ereny Mikhael, Amir Bishay, Benjamin W Van Voorhees
Background Evidence-based Internet depression prevention intervention programs are not readily available for Arab youth, but may be effective in this group. Cultural adaptation of evidence-based Western psychotherapy is an important step toward better prevention and treatment of depressive illness in the Arab community. Project CATCH-IT is an Internet-based depression prevention intervention tool that is tailored for adolescents and young adults. Methods The PEN-3 theoretical framework was used for the cultural adaptation of Project CATCH-IT for Arab adolescents...
July 18, 2017: International Journal of Adolescent Medicine and Health
https://www.readbyqxmd.com/read/28718190/-prevalence-and-risk-factors-of-myopia-in-children-and-adolescents-in-germany-results-of-the-kiggs-survey
#12
Alexander K Schuster, Heike M Elflein, Roman Pokora, Michael S Urschitz
Purpose To determine the population prevalence and risk factors of myopia in children and adolescents in Germany. Methods The prevalence of myopia in Germany was computed using data from the 2003-2006 German Health Interview and Examination Survey for Children and Adolescents (N=17 640, 49% girls). Status of myopia was derived from parental questionnaire responses for myopia and the use of spectacles. Potential risk factors were identified using directed acyclic graphs and evaluated using multivariable logistic regression analysis...
July 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28716389/biomedical-ethics-and-clinical-oversight-in-multisite-observational-neuroimaging-studies-with-children-and-adolescents-the-abcd-experience
#13
REVIEW
Duncan B Clark, Celia B Fisher, Susan Bookheimer, Sandra A Brown, John H Evans, Christian Hopfer, James Hudziak, Ivan Montoya, Margaret Murray, Adolf Pfefferbaum, Deborah Yurgelun-Todd
Observational neuroimaging studies with children and adolescents may identify neurological anomalies and other clinically relevant findings. Planning for the management of this information involves ethical considerations that may influence informed consent, confidentiality, and communication with participants about assessment results. Biomedical ethics principles include respect for autonomy, beneficence, non-maleficence, and justice. Each project presents unique challenges. The Adolescent Brain and Cognitive Development study (ABCD) collaborators have systematically developed recommendations with written guidelines for identifying and responding to potential risks that adhere to biomedical ethics principles...
June 28, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28714660/maternal-mortality-in-the-developed-world-a-review-of-surveillance-methods-levels-and-causes-of-maternal-deaths-during-2006-2010
#14
Andreea A Creanga
This article provides an overview of surveillance methods, levels, and causes of maternal mortality in developed countries (Europe and the United States) during 2006-2010. Accurate identification of maternal deaths is not always possible, and no two countries in the world use the same surveillance methods for maternal mortality. Despite limitations (underestimation, missclassification), routine vital registration systems are the backbone of maternal mortality surveillance systems in developed countries. Enhanced surveillance methods involve linkages between deaths of women of reproductive age and births within the preceding year, or the use of additional data sources for maternal deaths...
July 17, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28714534/adjustable-thermoplastic-oral-appliance-versus-positive-airway-pressure-for-obstructive-sleep-apnea
#15
Wish Banhiran, Paraya Assanasen, Cherdchai Nopmaneejumrudlers, Nongyoaw Nujchanart, Wimontip Srechareon, Cheerasook Chongkolwatana, Choakchai Metheetrairut
OBJECTIVES/HYPOTHESIS: To compare outcomes of continuous positive airway pressure (CPAP) and the adjustable thermoplastic mandibular advancement splint (AT-MAS) for obstructive sleep apnea treatment. STUDY DESIGN: Randomized crossover, noninferiority, tertiary center setting. METHODS: Fifty patients with a mean age of 49.5 ± 10.6 years were enrolled. Inclusion criteria were age ≥18 years, apnea-hypopnea index (AHI) ≥5 events/hour, and oxygen saturation ≥70%...
July 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28714531/using-patients-as-educators-for-communication-skills-exploring-dental-students-and-patients-views
#16
C Coelho, J Pooler, H Lloyd
TITLE: A qualitative study to explore the issues for patients and students when giving feedback on the communication of dental students. OBJECTIVES: The Department of Health and National Institute for Health Research are committed to involving patients in improving clinical education, research and service delivery. Yet, there is a limited body of evidence on the perceptions of patients when asked to be involved in this way, and specifically when asked to provide feedback on the communication skills of dental students...
July 17, 2017: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/28712359/resource-implications-of-preparing-individual-participant-data-from-a-clinical-trial-to-share-with-external-researchers
#17
Catrin Tudur Smith, Sarah Nevitt, Duncan Appelbe, Richard Appleton, Pete Dixon, Janet Harrison, Anthony Marson, Paula Williamson, Elizabeth Tremain
BACKGROUND: Demands are increasingly being made for clinical trialists to actively share individual participant data (IPD) collected from clinical trials using responsible methods that protect the confidentiality and privacy of clinical trial participants. Clinical trialists, particularly those receiving public funding, are often concerned about the additional time and money that data-sharing activities will require, but few published empirical data are available to help inform these decisions...
July 17, 2017: Trials
https://www.readbyqxmd.com/read/28710218/assessing-the-medium-term-impact-of-a-home-visiting-programme-on-child-maltreatment-in-england-protocol-for-a-routine-data-linkage-study
#18
Fiona V Lugg-Widger, Rebecca Cannings-John, Sue Channon, Deborah Fitzsimmons, Kerenza Hood, Kerina H Jones, Alison Kemp, Joyce Kenkre, Mirella Longo, Kirsten McEwan, Gwenllian Moody, Eleri Owen-Jones, Julia Sanders, Jeremy Segrott, Michael Robling
INTRODUCTION: Child maltreatment involves acts of omission (neglect) or commission (abuse) often by caregivers that results in potential or actual harm to a child. The Building Blocks trial (ISRCTN23019866) assessed the short-term impact of an intensive programme of antenatal and postnatal visiting by specially trained nurses to support young pregnant women in England. The Building Blocks: 2-6 Study will assess the medium-term impacts of the programme for mothers and children (n=1562), through the linkage of routinely collected data to the trial data, with a particular emphasis on the programme's impact on preventing child maltreatment...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28705215/feasibility-of-district-wide-screening-of-health-care-workers-for-tuberculosis-in-zambia
#19
Suzanne Verver, Nathan Kapata, Mathildah Kakungu Simpungwe, Seraphine Kaminsa, Mavis Mwale, Chitambeya Mukwangole, Bernard Sichinga, Sevim Ahmedov, Max Meis
BACKGROUND: Many health care workers (HCWs) are at increased risk for tuberculosis (TB). The World Health Organization (WHO) recommends screening HCWs for TB in high burden settings but this is often not implemented in countries with a high TB incidence. We assessed the feasibility of TB screening among HCWs, including participation rate and yield, as part of a project introducing facility specific TB interventions. METHODS: This study had a cross-sectional design...
July 14, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28700382/mandatory-reporting-of-intimate-partner-violence-an-ethical-dilemma-for-forensic-nurses
#20
Rosalyn M Walker
Nearly all states and provinces have laws mandating licensed healthcare professionals to report to law enforcement suspicions and allegations of the abuse of children, older adults, and disabled persons and all incidents of violence by a deadly weapon. However, a few states in the United States additionally mandate providers to report all injuries resultant from reported or suspected domestic/intimate partner violence. This can present a challenge to forensic nurses seeking to protect patient confidentiality and autonomy...
July 11, 2017: Journal of Forensic Nursing
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