keyword
https://read.qxmd.com/read/37813753/characteristics-of-blood-clotting-on-thromboelastography-in-patients-with-early-burns
#21
JOURNAL ARTICLE
Fang Jian, Chen Lu, He Jia, Li Na, Yang Peng, Bian Maohong, Chen Xulin
BACKGROUND: Thromboelastography (TEG) is a viscoelastic test that may be used to evaluate the hemostatic function of whole blood, and it may be useful for burn patients with multiple hemostatic defects. METHODS: We retrospectively recruited patients with burns between January 2019 and July 2021. Blood samples were drawn on admission and subjected to coagulation parameter assessment, including conventional coagulation tests and TEG assessment. Receiver operating characteristic (ROC) analysis was performed to predict the occurrence of complications in patients with early burns...
September 29, 2023: Transfusion and Apheresis Science
https://read.qxmd.com/read/37802703/analysis-of-fibrinolytic-shutdown-in-trauma-patients-with-traumatic-brain-injury
#22
JOURNAL ARTICLE
L Favors, K Harrell, V Miles, R C Hicks, M Rippy, H Parmer, A Edwards, C Brown, K Stewart, L Day, A Wilson, R Maxwell
BACKGROUND: Coagulation profiles following major trauma vary depending on injury pattern and degree of shock. The physiologic mechanisms involved in coagulation function at any given time are varied and remain poorly understood. Thromboelastography (TEG) has been used evaluate coagulation profiles in the trauma population with some reports demonstrating a spectrum of fibrinolysis to fibrinolytic shutdown on initial presentation. The objective of this study was to evaluate the fibrinolytic profile of patients with TBI using thromboelastography (TEG)...
September 26, 2023: American Journal of Surgery
https://read.qxmd.com/read/37639086/monitoring-of-electricity-generation-from-exhaust-waste-heat-and-wireless-data-recording-from-a-mobile-phone-in-real-driving-conditions-of-a-vehicle
#23
JOURNAL ARTICLE
Dinçer Akal, İlhan Umut
In this study, a system is designed to generate electrical energy from the exhaust waste heat of vehicles using a thermoelectric generator. Electronic hardware that can communicate wirelessly, firmware, and mobile software specific to the system have been developed to control and monitor this system. The system comprises hexagonal aluminum components, thermoelectric generators, a cooler, sensors, software, and electronic hardware. The easily removable hexagonal modular aluminum component is designed to transmit heat from the exhaust pipe to thermoelectric generators...
August 28, 2023: Environmental Science and Pollution Research International
https://read.qxmd.com/read/37600623/hypocoagulability-in-children-with-decompensated-chronic-liver-disease-and-sepsis-assessment-by-thromboelastography
#24
JOURNAL ARTICLE
Vignesh Vinayagamoorthy, Anshu Srivastava, Indranil Das, Anupam Verma, Prabhakar Mishra, Moinak Sen Sarma, Ujjal Poddar, Surender Kumar Yachha
OBJECTIVE: To evaluate the coagulation status of children with decompensated chronic liver disease (DCLD) and infection and factors affecting it using thromboelastography (TEG). METHODS: Coagulation status of children admitted with DCLD and infection was assessed by international normalized ratio (INR), platelet count, and TEG [reaction time (R), kinetic time (K), α-angle (AA), maximum amplitude (MA), coagulation index (CI), and lysis index (LY30)] at admission and at 7-14 days after treatment...
August 2023: JPGN reports
https://read.qxmd.com/read/37585414/acceptability-of-breast-milk-donor-banking-a-qualitative-study-among-health-workers-in-greater-accra-regional-hospital-ghana
#25
JOURNAL ARTICLE
Fred Kafui Tende, Adanna Uloaku Nwameme, Philip Teg-Nefaah Tabong
Despite the compelling evidence demonstrating the immediate and long-term health advantages of prompt breastfeeding from birth, not all newborns are breastfed exclusively for a variety of reasons. As a result, the World Health Organization has made new recommendations for the adoption of breastmilk donor banks to make sure that children receive breastmilk when mothers are unable to produce it. In order to better understand how health professionals at the Greater Accra Regional Hospital, who would be leading the charge in putting this policy into practice, perceive and accept the practice of storing breastmilk, this study was conducted...
2023: PLOS Glob Public Health
https://read.qxmd.com/read/37583887/pilot-implementation-of-community-health-advocacy-teams-to-improve-the-effectiveness-of-long-lasting-insecticide-net-distribution-through-both-campaigns-and-continuous-channels-in-ghana-a-qualitative-study-of-opportunities-and-barriers-to-implementation
#26
JOURNAL ARTICLE
Phyllis Dako-Gyeke, Ruby Hornuvo, Franklin N Glozah, Emmanuel Asampong, Philip Teg-Nefaah Tabong, Adanna Nwameme, Gloria M Chandi, Nana Yaw Peprah, David Gittelman, Philip B Adongo
INTRODUCTION: In Ghana, the National Malaria Elimination Programme (NMEP) distributes long-lasting insecticide net (LLIN) to households for free through the periodic point mass distribution (PMD) campaign and continuous distribution to populations most vulnerable to malaria. It is known that the existence of effective and functional community-based groups could influence positive behaviours regarding health interventions promoted through health campaigns. However, there is no evidence of functional community-based groups that aim to improve the effectiveness of LLIN distribution campaigns by transitioning into primary healthcare delivery...
2023: Frontiers in Public Health
https://read.qxmd.com/read/37568852/an-efficient-ensemble-approach-for-alzheimer-s-disease-detection-using-an-adaptive-synthetic-technique-and-deep-learning
#27
JOURNAL ARTICLE
Muhammad Mujahid, Amjad Rehman, Teg Alam, Faten S Alamri, Suliman Mohamed Fati, Tanzila Saba
Alzheimer's disease is an incurable neurological disorder that leads to a gradual decline in cognitive abilities, but early detection can significantly mitigate symptoms. The automatic diagnosis of Alzheimer's disease is more important due to the shortage of expert medical staff, because it reduces the burden on medical staff and enhances the results of diagnosis. A detailed analysis of specific brain disorder tissues is required to accurately diagnose the disease via segmented magnetic resonance imaging (MRI)...
July 26, 2023: Diagnostics
https://read.qxmd.com/read/37544920/evolution-of-thermoelectric-generators-from-application-to-hybridization
#28
REVIEW
Zhaojun Liu, Bian Tian, Yao Li, Zijun Guo, Zhongkai Zhang, Zhifang Luo, Libo Zhao, Qijing Lin, Chengkuo Lee, Zhuangde Jiang
Considerable thermal energy is emitted into the environment from human activities and equipment operation in the course of daily production. Accordingly, the use of thermoelectric generators (TEGs) can attract wide interest, and it shows high potential in reducing energy waste and increasing energy recovery rates. Notably, TEGs have aroused rising attention and been significantly boosted over the past few years, as the energy crisis has worsened. The reason for their progress is that thermoelectric generators can be easily attached to the surface of a heat source, converting heat energy directly into electricity in a stable and continuous manner...
August 6, 2023: Small
https://read.qxmd.com/read/37521965/exploring-microplastic-impact-on-whole-blood-clotting-dynamics-utilizing-thromboelastography
#29
JOURNAL ARTICLE
Alexei Christodoulides, Abigail Hall, Nathan J Alves
This study investigates the influence of microplastics on blood clotting. It addresses the lack of comprehensive research on the effects of microplastic size and surface modification on clotting dynamics in human whole blood. Thromboelastography was used to examine aminated (aPS), carboxylated (cPS), and non-functionalized (nPS) polystyrene particles with sizes of 50, 100, and 500  nm. Results show that cPS consistently activated the clotting cascade, demonstrating increased fibrin polymerization rates, and enhanced clot strength in a size and concentration-dependent manner...
2023: Frontiers in Public Health
https://read.qxmd.com/read/37509691/effect-of-10-day-treatment-with-50-mg-prednisolone-once-daily-on-haemostasis-in-healthy-men-a-randomised-placebo-controlled-trial
#30
JOURNAL ARTICLE
Peter Kamstrup, Ema Rastoder, Pernille Høgh Hellmann, Pradeesh Sivapalan, Emil List Larsen, Jørgen Vestbo, Charlotte Suppli Ulrik, Jens P Goetze, Filip Krag Knop, Jens Ulrik Stæhr Jensen
Synthetic corticosteroids are widely used due to their anti-inflammatory and immunosuppressant effects. Their use has been associated with venous thromboembolism, but it is unknown whether thromboembolism has a causal relationship with corticosteroid treatment. In a randomised, double-blind, placebo-controlled trial in normal to overweight healthy men, the effect of the corticosteroid prednisolone on haemostasis using either 50 mg prednisolone or matching placebo once daily for ten days was investigated. The primary outcome was a change from baseline in the viscoelastic measurement maximal amplitude of clot in kaolin-activated thromboelastography (TEG)...
July 21, 2023: Biomedicines
https://read.qxmd.com/read/37362492/thromboelastography-in-the-perioperative-period-a-literature-review
#31
REVIEW
Vendhan Ramanujam, Stephen DiMaria, Vivek Varma
Assessing coagulation status is essential for prompt intervention to reduce morbidity and mortality related to bleeding and thrombotic complications during the perioperative period. Traditional coagulation tests such as platelet count, activated partial thromboplastin time (aPTT), prothrombin time (PT), international normalized ratio (INR), and activated clotting time (ACT) provide only static evaluation. These tests are not designed for assessment of dynamically changing coagulation conditions during the perioperative time...
May 2023: Curēus
https://read.qxmd.com/read/37354664/applications-of-viscoelastic-testing-in-microsurgery-a-systemic-review-and-meta-analysis
#32
JOURNAL ARTICLE
A Hamidian Jahromi, S Arnold, P Konofaos
Viscoelastic testing including thromboelastography (TEG) and rotational thromboelastometry (ROTEM) has gained increasing popularity across many medical fields in recent years. As TEG/ROTEM testing uses whole blood sample and evaluates interactions between cellular components i.e., platelets, red blood cells and the clotting factors, these evaluations are uniquely capable of assessing coagulation in an in-vitro environment, resembling native conditions unlike those of conventual clotting tests (CCTs). While viscoelastic based protocols and applications are more commonplace in hepatic and cardiac surgery and trauma scenarios, results have attracted the attention of additional disciplines including microsurgery...
April 2023: Georgian Medical News
https://read.qxmd.com/read/37345636/multifunctional-narrow-band-gap-terpolymer-enabled-high-performance-dopant-free-perovskite-and-additive-free-organic-solar-cells-with-long-term-stability
#33
JOURNAL ARTICLE
Rajalapati Durga Gayathri, Chetan Lakshman, Hyerin Kim, Jeonghyeon Park, Donghyun Song, Jieun Lee, Ho-Yeol Park, Raja Kumaresan, Thavamani Gokulnath, Sung-Ho Jin
The optoelectronic devices endowing multifunctionality while utilizing a single low-cost material have always been challenging. For this purpose, we adopted a random ternary copolymerization strategy for designing two terpolymers, namely TP-0.8-EG and TP-0.8-TEG comprising a benzothiadiazole (BT)-benzo[1,2-b:4,5-b']dithiophene-diketopyrrolo[3,4- c ]pyrrole (A1 -π-D-π-A2 ) backbone. The figure of merits of the narrow band gap TP-0.8-EG terpolymer include deepened frontier energy levels, high hole mobility, better film formability, enriched multifunctionality, and passivation capability...
June 22, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/37331191/citrate-phosphate-dextrose-alters-coagulation-dynamics-ex%C3%A2-vivo
#34
JOURNAL ARTICLE
Jacob B Schriner, Atharwa Mankame, Scott D Olson, Charles S Cox, Brijesh S Gill
INTRODUCTION: Citrate-phosphate-dextrose (CPD) is the most common anticoagulant for blood product storage in the United States. It was developed to prolong shelf life, though there is little research regarding its impact on function following transfusion. We used flow cytometry (FC), thromboelastography (TEG), and a clot contraction assay called the zFlex platform to measure platelet activation and global clot formation in blood samples anticoagulated with either CPD or in a standard blue top citrate (BTC) tube...
June 16, 2023: Journal of Surgical Research
https://read.qxmd.com/read/37321608/clinical-application-of-thromboelastography-in-patients-with-severe-fever-with-thrombocytopenia-syndrome
#35
JOURNAL ARTICLE
Yingbo Li, Changjuan An, Peng Xue, Lina Ni, Xia Yu, Jiangli Qu, Yingjie Yao, Chengyong Yu
AIM: To investigate the clinical application of thromboelastography (TEG) in severe fever with thrombocytopenia syndrome (SFTS). METHODS: One hundred and fifty-seven patients with SFTS were included in the study. The participants were distributed into 3 groups; A, B, and C. And 103 patients in group A met the clinical criteria as they exhibited slight liver and kidney dysfunction. Group B consisted of 54 patients with SFTS who were critically ill while group C was a healthy control group with 58 participants...
2023: Clinical and Applied Thrombosis/hemostasis
https://read.qxmd.com/read/37231446/capacity-building-through-comprehensive-implementation-research-training-and-mentorship-an-approach-for-translating-knowledge-into-practice
#36
JOURNAL ARTICLE
Emmanuel Asampong, Edward Mberu Kamau, Philip Teg-Nefaah Tabong, Franklin Glozah, Adanna Nwameme, Kwabena Opoku-Mensah, Belynda Amankwa, Phyllis Dako-Gyeke
BACKGROUND: Implementation research (IR) is increasingly gaining popularity as the act of carrying an intention into effect. It is thus an important approach to addressing individual practices, policies, programmes and other technologies to solving public health problems. Low- and middle-income countries (LMICs) continue to experience public health problems which could be addressed using implementation research. These countries however fall behind prioritizing implementation research due to the disorganized approach used to providing knowledge about the value and scope of implementation research...
May 25, 2023: Globalization and Health
https://read.qxmd.com/read/37212090/diagnostic-value-of-mean-platelet-volume-combined-with-thromboelastography-for-coagulation-state-after-total-knee-arthroplasty
#37
JOURNAL ARTICLE
Jia-Hao Chen, Qiang Zhang, Hu Wang, Hang Zhou, Sun Jianning, Xiang-Yang Chen, Shuo Feng
BACKGROUND: The main objective of this study was to predict the status of blood and the occurrence of lower limb deep vein thrombosis (DVT) after total knee arthroplasty(TKA) by means of mean platelet volume (MPV) combined with thromboelastography (TEG). METHODS: We collected 180 patients who underwent unilateral total knee arthroplasty between May 2015 and March 2022, and the patients were divided into DVT group and control group according to whole-leg ultrasonography on the seventh postoperative day...
May 18, 2023: Clinical Hemorheology and Microcirculation
https://read.qxmd.com/read/37204750/the-quantra-system-system-description-and-protocols-for-measurements
#38
JOURNAL ARTICLE
Oksana Volod, Francesco Viola
Over the past two decades, the TEG 5000 (Haemonetics Corp, Braintree, MA) and ROTEM delta (Werfen, Bedford, MA) have been the principal viscoelastic (VET) technologies. These legacy technologies are based on the "cup and pin" principle. The Quantra System (HemoSonics, LLC, Durham, NC) is a new device that assesses blood viscoelastic properties by ultrasound (SEER Sonorheometry). It is cartridge based, automated device that provides simplified specimen management and increased results reproducibility. In the present chapter, we provide a description of the Quantra and its principle of operation, currently available cartridges/assays with their respective clinical indications, device operation, and results interpretation...
2023: Methods in Molecular Biology
https://read.qxmd.com/read/37204725/monitoring-of-antiplatelet-therapy
#39
JOURNAL ARTICLE
Simon Davidson
In the late 1990s, the antithrombotic antiplatelet agent, clopidogrel, a P2Y12 inhibitor, was introduced. Around the same time, there was an increase in a number of new methods to measure platelet function (e.g., PFA-100 in 1995), and this has continued. It became evident that not all patients responded to clopidogrel in the same way and that some patients had a relative "resistance" to therapy, termed "high on-treatment platelet reactivity." This then led to some publications to advocate platelet function testing being used for patients on antiplatelet therapy...
2023: Methods in Molecular Biology
https://read.qxmd.com/read/37198530/identification-of-essential-proteins-based-on-edge-features-and-the-fusion-of-multiple-source-biological-information
#40
JOURNAL ARTICLE
Peiqiang Liu, Chang Liu, Yanyan Mao, Junhong Guo, Fanshu Liu, Wangmin Cai, Feng Zhao
BACKGROUND: A major current focus in the analysis of protein-protein interaction (PPI) data is how to identify essential proteins. As massive PPI data are available, this warrants the design of efficient computing methods for identifying essential proteins. Previous studies have achieved considerable performance. However, as a consequence of the features of high noise and structural complexity in PPIs, it is still a challenge to further upgrade the performance of the identification methods...
May 17, 2023: BMC Bioinformatics
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