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https://www.readbyqxmd.com/read/29773657/review-of-the-role-of-nice-in-promoting-the-adoption-of-innovative-cardiac-technologies
#1
REVIEW
Peter H Groves, Chris Pomfrett, Mirella Marlow
The National Institute for Health and Care Excellence (NICE) Medical Technologies Evaluation Programme (MTEP) promotes the adoption of innovative diagnostic and therapeutic technologies into National Health Service (NHS) clinical practice through the publication of guidance and briefing documents. Since the inception of the programme in 2009, there have been 7 medical technologiesguidance, 3 diagnostics guidance and 23 medtechinnovation briefing documents published that are relevant to the heart and circulation...
May 17, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29768451/intravitreal-ocriplasmin-for-the-treatment-of-vitreomacular-traction-and-macular-hole-a-study-of-efficacy-and-safety-based-on-nice-guidance
#2
Mahiul M K Muqit, Robin Hamilton, Jason Ho, Sally Tucker, Helen Buck
PURPOSE: To evaluate the real world clinical outcomes of intravitreal ocriplasmin in patients with vitreomacular traction (VMT) with and without full thickness macular holes (FTMH) treated according to NICE guidance. METHODS: Retrospective observational case series of 25 patients treated with a single intravitreal ocriplasmin injection between December 2013 and December 2015. Best corrected visual acuity and optical coherence tomography exams were performed to determine visual outcomes and anatomical VMT release and FTMH closure over time...
2018: PloS One
https://www.readbyqxmd.com/read/29761488/psychological-therapies-for-treatment-resistant-depression-in-adults
#3
REVIEW
Sharea Ijaz, Philippa Davies, Catherine J Williams, David Kessler, Glyn Lewis, Nicola Wiles
BACKGROUND: Antidepressants are a first-line treatment for adults with moderate to severe major depression. However, many people prescribed antidepressants for depression don't respond fully to such medication, and little evidence is available to inform the most appropriate 'next step' treatment for such patients, who may be referred to as having treatment-resistant depression (TRD). National Institute for Health and Care Excellence (NICE) guidance suggests that the 'next step' for those who do not respond to antidepressants may include a change in the dose or type of antidepressant medication, the addition of another medication, or the start of psychotherapy...
May 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29703590/how-effective-is-trauma-simulation-as-an-educational-process-for-healthcare-providers-within-the-trauma-networks-a-systematic-review
#4
Donna Barleycorn, Geraldine A Lee
BACKGROUND: Major trauma is a significant public health problem and a leading cause of death for several age groups. To address this issue, Major Trauma Networks were introduced in the UK from 2010, consisting of Major Trauma Centres (MTCs) and a network of linked Trauma Units (TUs). OBJECTIVE: The aim is to undertake a systematic review to examine how effective is trauma simulation as an educational process for healthcare providers within trauma networks. METHODS: The databases searched included Medline, Embase and Cinahl from 2010 to 2016...
April 24, 2018: International Emergency Nursing
https://www.readbyqxmd.com/read/29691773/etelcalcetide-for-treating-secondary-hyperparathyroidism-an-evidence-review-group-evaluation-of-a-nice-single-technology-appraisal
#5
Micah Rose, Jonathan Shepherd, Petra Harris, Karen Pickett, Joanne Lord
The manufacturer of the calcimimetic drug etelcalcetide was invited to make an evidence submission as part of the National Institute for Health and Care Excellence (NICE) Single Technology Appraisal (STA) programme. Within this submission, they reported evidence on the clinical and cost effectiveness of etelcalcetide for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) on haemodialysis. The Southampton Health Technology Assessments Centre (SHTAC), part of the Wessex Institute at the University of Southampton, was the independent Evidence Review Group (ERG) commissioned to appraise the company's submission...
April 25, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29683792/decision-making-for-healthcare-resource-allocation-joint-v-separate-decisions-on-interacting-interventions
#6
Helen Dakin, Alastair Gray
Standard guidance for allocating healthcare resources based on cost-effectiveness recommends using different decision rules for independent and mutually exclusive alternatives, although there is some confusion around the definition of "mutually exclusive." This paper reviews the definitions used in the literature and shows that interactions (i.e., non-additive effects, whereby the effect of giving 2 interventions simultaneously does not equal the sum of their individual effects) are the defining feature of mutually exclusive alternatives: treatments cannot be considered independent if the costs and/or benefits of one treatment are affected by the other treatment...
May 2018: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/29681615/impact-of-nice-guidance-on-tamoxifen-prescribing-in-england-2011-2017-an-interrupted-time-series-analysis
#7
Helen J Curtis, Alex J Walker, Ben Goldacre
BACKGROUND: Tamoxifen was recommended by NICE in 2013 for chemoprevention of breast cancer, but a recent survey suggested only a quarter of GPs are aware of this. We set out to measure the uptake of tamoxifen, and the alternative raloxifene, in national prescribing data sets. METHODS: Tamoxifen and raloxifene data were extracted from England's monthly prescribing data sets, October 2010-October 2017. We used interrupted time series analysis to reveal national and local responses to guidelines...
April 23, 2018: British Journal of Cancer
https://www.readbyqxmd.com/read/29659715/the-cost-effectiveness-of-follow-up-strategies-after-cancer-treatment-a-systematic-literature-review
#8
M Barbieri, G Richardson, S Paisley
Introduction: The cost of treatment and follow-up of cancer patients in the UK is substantial. In a budget-constrained system such as the NHS, it is necessary to consider the cost-effectiveness of the range of management strategies at different points on cancer patients' care pathways to ensure that they provide adequate value for money. Sources of data: We conducted a systematic literature review to explore the cost-effectiveness of follow-up strategies of patients previously treated for cancer with the aim of informing UK policy...
April 12, 2018: British Medical Bulletin
https://www.readbyqxmd.com/read/29650513/lyme-disease-summary-of-nice-guidance
#9
Maria Cruickshank, Norma O'Flynn, Saul N Faust
No abstract text is available yet for this article.
April 12, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29648607/nice-public-health-guidance-update
#10
Johanna Hulme, Ruth Garnett, Louise Picton, Fiona Glen, Gillian Leng
No abstract text is available yet for this article.
April 10, 2018: Journal of Public Health
https://www.readbyqxmd.com/read/29623616/does-methodological-guidance-produce-consistency-a-review-of-methodological-consistency-in-breast-cancer-utility-value-measurement-in-nice-single-technology-appraisals
#11
REVIEW
Micah Rose, Stephen Rice, Dawn Craig
Since 2004, National Institute for Health and Care Excellence (NICE) methodological guidance for technology appraisals has emphasised a strong preference for using the validated EuroQol 5-Dimensions (EQ-5D) quality-of-life instrument, measuring patient health status from patients or carers, and using the general public's preference-based valuation of different health states when assessing health benefits in economic evaluations. The aim of this study was to review all NICE single technology appraisals (STAs) for breast cancer treatments to explore consistency in the use of utility scores in light of NICE methodological guidance...
July 5, 2017: PharmacoEconomics Open
https://www.readbyqxmd.com/read/29622470/clinician-tasking-in-ambulance-control-improves-the-identification-of-major-trauma-patients-and-pre-hospital-critical-care-team-tasking
#12
Neil Sinclair, Paul A Swinton, Michael Donald, Lisa Curatolo, Peter Lindle, Steph Jones, Alasdair R Corfield
INTRODUCTION: Trauma remains the fourth leading cause of death in western countries and is the leading cause of death in the first four decades of life. NICE guidance in 2016 advocated the attendance of pre-hospital critical care trauma team (PHCCT) in the pre-hospital stage of the care of patients with major trauma. Previous publications support dispatch by clinicians who are also actively involved in the delivery of the PHCCT service; however there is a lack of objective outcome measures across the current reviewed evidence base...
March 30, 2018: Injury
https://www.readbyqxmd.com/read/29617060/a-prospective-real-world-analysis-of-onabotulinumtoxina-in-chronic-migraine-post-nice-u-k-technology-appraisal
#13
Anna P Andreou, Michele Trimboli, Adnan Al-Kaisy, Madeleine Murphy, Stefano Palmisani, Cherylin Fenech, Thomas Smith, Giorgio Lambru
OBJECTIVES: The National Institute for Health and Care Excellence (NICE) in the United Kingdom (UK) recommend the use of OnabotulinumtoxinA (BoNTA, Botox® ) in the management of chronic migraine (CM) following specific guidelines within the National Health Service (NHS). In view of the lack of data on the efficacy of this therapy following implementation of this guidelines in clinical practice and on the evaluation of guidance' compliance, we evaluate the effectiveness and safety of BoNTA in CM patients following the NICE guidelines...
April 4, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29616460/the-memokath-051-stent-for-the-treatment-of-ureteric-obstruction-a-nice-medical-technology-guidance
#14
REVIEW
Emily Eaton Turner, Michelle Jenks, Rachael McCool, Chris Marshall, Liesl Millar, Hannah Wood, Alison Peel, Joyce Craig, Andrew J Sims
Memokath-051 is a thermo-expandable, nickel-titanium alloy spiral stent used to treat ureteric obstruction resulting from malignant or benign strictures. The National Institute for Health and Care Excellence (NICE) selected Memokath-051 for evaluation. The company, PNN Medical, claimed Memokath-051 has clinical superiority and cost savings compared with double-J stents. It identified five studies reporting clinical evidence on Memokath-051 and constructed a de novo cost model comparing Memokath-051 to double-J stents...
April 3, 2018: Applied Health Economics and Health Policy
https://www.readbyqxmd.com/read/29600384/paclitaxel-as-albumin-bound-nanoparticles-with-gemcitabine-for-untreated-metastatic-pancreatic-cancer-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#15
REVIEW
Angela Stainthorpe, Janette Greenhalgh, Adrian Bagust, Marty Richardson, Angela Boland, Sophie Beale, Rui Duarte, Eleanor Kotas, Lindsay Banks, Daniel Palmer
As part of the single technology appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited Celgene Ltd to submit clinical and cost-effectiveness evidence for paclitaxel as albumin-bound nanoparticles (Nab-Pac) in combination with gemcitabine (Nab-Pac + Gem) for patients with untreated metastatic pancreatic cancer. The STA was a review of NICE's 2015 guidance (TA360) in which Nab-Pac + Gem was not recommended for patients with untreated metastatic pancreatic cancer...
March 29, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29594951/obinutuzumab-with-bendamustine-for-treating-follicular-lymphoma-refractory-to-rituximab-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#16
REVIEW
Rachid Rafia, Abdullah Pandor, Sarah Davis, John W Stevens, Sue Harnan, Mark Clowes, Youssef Sorour, Robert Cutting
As part of its single technology appraisal process, the UK National Institute for Health and Care Excellence (NICE) invited the manufacturer of obinutuzumab (Roche) to submit evidence on its clinical and cost effectiveness when used in combination with bendamustine in patients with follicular lymphoma (FL) refractory to rituximab. The Evidence Review Group (ERG), the School of Health and Related Research Technology Appraisal Group at the University of Sheffield, produced a document summarising the key points from the company submission alongside a critical review...
March 28, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29591538/quality-measurement-recommendations-relevant-to-clinical-guidelines-in-germany-and-the-united-kingdom-what-can-we-learn-from-each-other
#17
Thomas Petzold, Stefanie Deckert, Paula R Williamson, Jochen Schmitt
We conducted a systematic review of clinical guidelines (CGs) to examine the methodological approaches of quality indicator derivation in CGs, the frequency of quality indicators to check CG recommendations in routine care, and clinimetric properties of quality indicators. We analyzed the publicly available CG databases of the Association of the Scientific Medical Societies in Germany (AWMF) and National Institute for Health and Care Excellence (NICE). Data on the methodology of subsequent quality indicator derivation, the content and definition of recommended quality indicators, and clinimetric properties of measurement instruments were extracted...
January 2018: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/29588835/challenging-current-views-on-bile-acid-diarrhoea-and-malabsorption
#18
REVIEW
Matthew Kurien, Elizabeth Thurgar, Ashley Davies, Ron Akehurst, Jervoise Andreyev
Background: In 2012, the National Institute for Health and Care Excellence (NICE) assessed guidance (DG7) on the use of tauroselcholic (75 selenium) acid (also known as SeHCAT) for the investigation of diarrhoea due to bile acid malabsorption (BAM) in patients with IBS-D and in patients with Crohn's disease who have not had an ileal resection. NICE concluded that tauroselcholic (75 selenium) acid was recommended for use in research only. NICE will be reviewing the decision to update the guidance for tauroselcholic (75 selenium) acid, for these populations, in March 2017...
April 2018: Frontline Gastroenterology
https://www.readbyqxmd.com/read/29582406/reslizumab-for-treating-asthma-with-elevated-blood-eosinophils-inadequately-controlled-by-inhaled-corticosteroids-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#19
REVIEW
Keith Cooper, Geoff Frampton, Petra Harris, Micah Rose, Maria Chorozoglou, Karen Pickett
As part of the National Institute for Health and Care Excellence (NICE) Single Technology Appraisal (STA) process, the manufacturer of reslizumab (Teva) submitted evidence for its clinical and cost effectiveness for the treatment of eosinophilic asthma inadequately controlled by inhaled corticosteroids. NICE commissioned Southampton Health Technology Assessments Centre (SHTAC) as an independent Evidence Review Group (ERG) to provide a critique of the manufacturer's submitted evidence. Reslizumab is compared with best standard of care and omalizumab, for a small 'overlap' population of patients who have both eosinophilic and IgE-mediated severe asthma...
May 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29574425/blood-transfusion-practice-in-the-uk-and-ireland-a-survey-of-palliative-care-physicians
#20
Karen Neoh, Simon Stanworth, Michael I Bennett
OBJECTIVES: Red cell (blood) transfusions are used in palliative care to manage patients with symptomatic anaemia or when patients have lost blood. We aimed to understand current blood transfusion practice among palliative medicine doctors and compare this with National Institute for Health and Care Excellence (NICE) guidance. NICE guidance advocates more restrictive transfusion practice but is based on clinical trials in non-palliative care contexts; the extent to which these findings should be applied to palliative care remains unclear...
March 23, 2018: BMJ Supportive & Palliative Care
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