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https://www.readbyqxmd.com/read/29650489/guiding-hand-hygiene-interventions-among-future-healthcare-workers-implications-of-knowledge-attitudes-and-social-influences
#1
Shamsul Arfin Qasmi, Sayed Mustafa Mahmood Shah, Hafiz Yahya Iftikhar Wakil, Sarmad Pirzada
BACKGROUND: Medical students in their clinical years play an important role in healthcare delivery, yet poor levels of hand hygiene (HH) compliance in this population raise the risk for propagating nosocomial infections. To date, there has been a lack of dedicated interventions showing sustainable improvements in HH in this population. METHODS: A multicenter, cross-sectional study was conducted among 450 medical students in their clinical years (third to fifth years)...
April 9, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29650487/speaking-up-about-hand-hygiene-failures-a-vignette-survey-study-among-healthcare-professionals
#2
David L B Schwappach
BACKGROUND: Speaking up by healthcare professionals (HCPs) is an important resource to reduce risks to patient safety. Due to complex tradeoffs, HCPs are often reluctant to voice their concerns. A survey investigated HCPs' likelihood to speak up. METHODS: A cross-sectional survey study among HCPs in 5 Swiss hospitals addressed speaking-up behaviors, safety climate, and likelihood to speak up about poor hand hygiene practice described in a vignette. Likelihood to speak up was analyzed using a multilevel regression model...
April 9, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29650033/enterovirus-serotypes-in-patients-with-central-nervous-system-and-respiratory-infections-in-viet-nam-1997-2010
#3
Nguyen Thi Thuy Chinh B'Krong, Ngo Ngoc Quang Minh, Phan Tu Qui, Tran Thi Hong Chau, Ho Dang Trung Nghia, Lien Anh Ha Do, Nguyen Ngoc Nhung, Nguyen Van Vinh Chau, Guy Thwaites, Le Van Tan, H Rogier van Doorn, Tran Tan Thanh
BACKGROUND: Enteroviruses are the most common causative agents of human illness. Enteroviruses have been associated with regional and global epidemics, recently, including with severe disease (Enterovirus A71 and D68), and are of interest as emerging viruses. Here, we typed Enterovirus A-D (EV) from central nervous system (CNS) and respiratory infections in Viet Nam. METHODS: Data and specimens from prospective observational clinical studies conducted between 1997 and 2010 were used...
April 12, 2018: Virology Journal
https://www.readbyqxmd.com/read/29649556/is-there-a-relationship-between-airborne-and-surface-microbes-in-the-critical-care-environment
#4
J Smith, C A Adams, M F King, C J Noakes, C Robertson, S J Dancer
OBJECTIVE: This study attempted firstly to correlate environmental contamination of air and surfaces in the intensive care unit (ICU); and secondly, to examine any association between environmental contamination and ICU-acquired staphylococcal infection. DESIGN: We screened patients, air and surfaces on 10 sampling days in a mechanically ventilated 10-bed ICU during 10 months. METHODS: Near-patient hand-touch sites (n=500) and air (n=80) were screened for total colony count and Staphylococcus aureus using dipslides, settle plates (passive air sampling) and an MAS-100 slit-sampler (active air sampling)...
April 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29649553/the-interplay-between-dose-and-immune-system-activation-determines-fungal-infection-outcome-in-the-african-malaria-mosquito-anopheles-gambiae
#5
Victoria L Rhodes, Matthew B Thomas, Kristin Michel
The Toll pathway is a central regulator of antifungal immunity in insects. In mosquitoes, the Toll pathway affects infections with the fungal entomopathogen, Beauveria bassiana, which is considered a potential mosquito biopesticide. We report here the use of B. bassiana strain I93-825 in Anopheles gambiae to analyze the impact of Toll pathway modulation on mosquito survival. Exposure to a narrow dose range of conidia by direct contact decreased mosquito longevity and median survival. In addition, fungal exposure dose correlated positively and linearly with hazard ratio...
April 9, 2018: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29648477/acute-intensive-care-unit-management-of-mustard-gas-victims-the-turkish-experience
#6
Ertugrul Kilic, Mesut Ortatatli, Sermet Sezigen, Rusen Koray Eyison, Levent Kenar
Sulfur mustard (SM) is an highly toxic and vesicant chemical weapon that was used in various military conflicts several times in the history. The severity of ocular, dermal, and pulmonary symptoms that may appear following a characteristic asymptomatic period are depending on the SM concentration and exposure duration. The aim of this study is to present the clinical features and share the intensive care unit (ICU) experiences for the medical management of mustard gas victims. Thirteen Free Syrian Army soldiers near Al-Bab region of North Syria were reportedly exposed to oily blackish smoke with garlic smell due to the explosion of a trapped bomb without causing any blast or thermal effect on 26th November 2016...
April 12, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29644540/molecular-epidemiology-of-carbapenem-resistant-pseudomonas-aeruginosa-in-an-endemic-area-comparison-with-global-data
#7
REVIEW
Theodoros Karampatakis, Charalampos Antachopoulos, Athanassios Tsakris, Emmanuel Roilides
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is an endemic problem in certain countries including Greece. CRPA and multidrug-resistant P. aeruginosa (MDRPA) firstly emerged in our region during the 80s, right after the launch of imipenem and meropenem as therapeutic agents against P. aeruginosa infections. The role of outer membrane protein (Opr) inactivation has been known to contribute to imipenem resistance since many years, while efflux overexpression systems have been mainly associated with meropenem resistance...
April 11, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29644292/serious-phlegmonous-lesion-of-the-hand-following-an-injury-by-vegetal-thorn-never-forget-pasteurella-multocida
#8
A Maleb, J Elmalki, O Bouayadi, Y Ben Lahlou, M Frikh, N Abdeljaouad, A Lemnouer, H Yacoubi, M Elouennass
Pasteurella multocida can cause serious infections after dog or cat bite. We report here a rare case of hand infection caused by P. multocida consecutive to an injury by a thorn of the prickly pear. It caused an amputation of the distal phalanx of the thumb in a trisomic patient. It is about a 27-year-old man who was admitted to the hospital with swelling and intense pain of the left hand. He reported a sting by a thorn of prickly pear 15 days before. The patient was admitted to proceed with operative irrigation and debridement...
February 2018: Trauma Case Reports
https://www.readbyqxmd.com/read/29642942/molecular-identification-of-badger-associated-babesia-sp-dna-in-dogs-updated-phylogeny-of-piroplasms-infecting-caniformia
#9
Sándor Hornok, Gábor Horváth, Nóra Takács, Jenő Kontschán, Krisztina Szőke, Róbert Farkas
BACKGROUND: Piroplasms are unicellular, tick-borne parasites. Among them, during the past decade, an increasing diversity of Babesia spp. has been reported from wild carnivores. On the other hand, despite the known contact of domestic and wild carnivores (e.g. during hunting), and a number of ixodid tick species they share, data on the infection of dogs with babesiae from other families of carnivores are rare. METHODS: In this study blood samples were collected from 90 dogs and five road-killed badgers...
April 11, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29642825/-investigation-of-carbapenemase-genes-and-molecular-epidemiology-of-enterobacteriaceae-strains-isolated-between-2010-2014-in-a-university-hospitals
#10
Hüseyin Haydar Kutlu, Ebru Us, Alper Tekeli
The worldwide spread of carbapenemase producing Enterobacteriaceae isolates has become a major threat of public health. This worrisome situation leads the development of new methods for carbapenemase screening, detection, prevention of spread and epidemiological data collection as mandatory. In this study, it was aimed to investigate existence and distribution of carbapenemase-encoding genes (CEGs) among carbapenem-resistant Enterobacteriaceae isolated from various clinical samples in Ankara University Faculty of Medicine, Ibni Sina Hospital, Central Microbiology Laboratory between June 2010-May 2014 and detect their clonal relationship...
January 2018: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/29629382/get-aware-of-hand-hygiene-implement-it-in-your-attitude
#11
Gitali Bhagawati
BACKGROUND: Although there is advancement in the health-care system, the rates of hospital-acquired infections (HAIs) are still high. Poor hand hygiene (HH) among healthcare workers (HCWs) is identified as one of the major causes of HAIs. AIMS: The aim and objective of this study is to assess the awareness and attitude regarding hand hygiene (HH) among HCWs in a superspecialty hospital in Ghaziabad, Uttar Pradesh, India. SETTINGS AND DESIGN: A cross-sectional, semi-structured, questionnaire-based study was carried out in a superspecialty hospital, Uttar Pradesh, India...
2018: Journal of Education and Health Promotion
https://www.readbyqxmd.com/read/29628959/a-survey-of-nurses-compliance-with-hand-hygiene-guidelines-in-caring-for-patients-with-cancer-in-a-selected-center-of-isfahan-iran-in-2016
#12
Mostafa Mostafazadeh-Bora, Masoud Bahrami, Abbas Hosseini
Background: Hand hygiene is one of the key ways of preventing healthcare-associated infections (HCAI), especially in patients with cancer. The aim of this study was to determine nurses' compliance with hand hygiene guidelines in caring for patients with cancer in a selected center in Isfahan, Iran, in 2016. Materials and Methods: The present observational study was conducted on nurses in a cancer center in Isfahan in 2016. The participants were selected via convenience sampling method...
March 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29628916/multidrug-resistant-ctx-m-15-9-2-and-kpc-2-producing-enterobacter-hormaechei-and-enterobacter-asburiae-isolates-possessed-a-set-of-acquired-heavy-metal-tolerance-genes-including-a-chromosomal-sil-operon-for-acquired-silver-resistance
#13
Leonardo N Andrade, Thiago E S Siqueira, Roberto Martinez, Ana Lucia C Darini
Bacterial resistance to antibiotics is concern in healthcare-associated infections. On the other hand, bacterial tolerance to other antimicrobials, like heavy metals, has been neglected and underestimated in hospital pathogens. Silver has long been used as an antimicrobial agent and it seems to be an important indicator of heavy metal tolerance. To explore this perspective, we searched for the presence of acquired silver resistance genes ( sil operon: silE, silS, silR, silC, silF, silB, silA , and silP ) and acquired extended-spectrum cephalosporin and carbapenem resistance genes ( bla CTX-M and bla KPC ) in Enterobacter cloacae Complex (EcC) ( n = 27) and Enterobacter aerogenes ( n = 8) isolated from inpatients at a general hospital...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29628472/hcn4-overexpressing-mouse-embryonic-stem-cell-derived-cardiomyocytes-generate-a-new-rapid-rhythm-in-rats-with-bradycardia
#14
Yukihiro Saito, Kazufumi Nakamura, Masashi Yoshida, Hiroki Sugiyama, Makoto Takano, Satoshi Nagase, Hiroshi Morita, Kengo F Kusano, Hiroshi Ito
A biological pacemaker is expected to solve the persisting problems of an artificial cardiac pacemaker including short battery life, lead breaks, infection, and electromagnetic interference. We previously reported HCN4 overexpression enhances pacemaking ability of mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs) in vitro. However, the effect of these cells on bradycardia in vivo has remained unclear. Therefore, we transplanted HCN4-overexpressing mESC-CMs into bradycardia model animals and investigated whether they could function as a biological pacemaker...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29626377/classic-paper-are-the-chickenpox-virus-and-the-zoster-virus-identical-helmut-ruska
#15
Detlev H Kruger, Thomas Mertens
As early as 1943, the German physician Helmut Ruska visualized the virus of varicella and zoster (at that time, he was not completely certain whether the virus was the same) by the newly developed electron microscope; he is regarded as the discoverer of this virus. Here, we present a translation of his classical paper into the English language. In our introduction and commentary to his paper, we discuss the significance of Helmut Ruska's work for the development of virology, his distinction between the varicella, zoster, and herpes virus group on one hand and poxviruses on the other, as well as the development of imaging techniques which have refined or substituted for electron microscopy of viruses and virus-infected cells...
April 6, 2018: Reviews in Medical Virology
https://www.readbyqxmd.com/read/29626210/the-life-cycle-of-non-polio-enteroviruses-and-how-to-target-it
#16
REVIEW
Jim Baggen, Hendrik Jan Thibaut, Jeroen R P M Strating, Frank J M van Kuppeveld
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus, coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse viruses cause a variety of diseases, including non-specific febrile illness, hand-foot-and-mouth disease, neonatal sepsis-like disease, encephalitis, paralysis and respiratory diseases. In recent years, several non-polio enteroviruses (NPEVs) have emerged as serious public health concerns. These include EV-A71, which has caused epidemics of hand-foot-and-mouth disease in Southeast Asia, and EV-D68, which recently caused a large outbreak of severe lower respiratory tract disease in North America...
April 6, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29623091/the-prevalence-and-underreporting-of-needlestick-injuries-among-dental-healthcare-workers-in-pakistan-a-systematic-review
#17
REVIEW
Mehak Pervaiz, Ruth Gilbert, Nasreen Ali
Needlestick injuries (NSIs) are a major occupational health problem among dental healthcare workers (HCWs) in Pakistan, which places them at a significant risk of acquiring blood-borne infections. However, not all NSIs are reported, leading to an underestimation of the actual prevalence. The harmful impacts of NSIs on the healthcare delivery necessitate an urgent need to measure its actual prevalence. Objectives . The aim of this study was to review literature to estimate the prevalence and reporting rates of NSIs among dental-HCWs in Pakistan...
2018: International Journal of Dentistry
https://www.readbyqxmd.com/read/29622909/anemia-among-hiv-infected-individuals-taking-art-with-and-without-zidovudine-at-addis-ababa-ethiopia
#18
Zemenu Tamir, Jemal Alemu, Aster Tsegaye
Background: Hematological complications such as Zidovudine(ZDV) associated anemia are among the commonly reported adverse drug reactions of Antiretroviral Therapy(ART). Little is known about ZDV associated anemia in developing countries like Ethiopia. Methods: Comparative retrospective cohort study was conducted at the ART Clinic of St. Paul Hospital Millennium Medical College from February 2011 to December 2012 to characterize anemia among HIV/AIDS patients initiated with ZDV and non-ZDV containing ART regimens...
January 2018: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29622908/soil-contamination-rate-prevalence-intensity-of-infection-of-geohelminths-and-associated-risk-factors-among-residents-in-bazou-west-cameroon
#19
Blandine Ngatou Tchakounté, Vanessa Rosine Nkouayep, Josué Wabo Poné
Background: Soil-transmitted helminths (STH) infections remain an important public health problem in the tropics. This study aimed to evaluate the soil contamination rate and prevalence of infestations of geohelminth among residents in Bazou. Methods: Four hundred (400) soil samples and 182 stool specimens were collected respectively from four sites and from inhabitants aged 1 to 40 years and above in 12 households. A questionnaire was administered to evaluate risk factors of STH-infections...
January 2018: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29622706/-klebsiella-endophthalmitis-as-the-herald-of-occult-colorectal-cancer
#20
Chun Yue Mak, Helena Pui-Yee Sin, Vesta Cheuk-Ki Chan, Alvin Young
A 67-year-old Chinese man presented with acute loss of vision and pain in the left eye with hypopyon in the anterior chamber. The patient was afebrile with no systemic symptoms at presentation. Diagnosis of endogenous endophthalmitis was made with vitreous tap yielding Klebsiella pneumoniae Pars plana vitrectomy was performed twice to clear the infection. Thorough investigations showed no septic foci. Whole body positron emission tomography CT revealed a rectal tumour and biopsy showed adenocarcinoma. He was treated with neoadjuvant chemoirradiation followed by surgery to resect the tumour...
April 5, 2018: BMJ Case Reports
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