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https://www.readbyqxmd.com/read/27862959/understanding-zika-virus
#1
John S Murray
PURPOSE: This article describes what pediatric healthcare professionals should know about Zika virus (ZIKV). LITERATURE REVIEW: ZIKV is classified as an arthropod-borne, single-stranded RNA virus of the Flaviviridae family and genus Flavivirus. ZIKV is not new. The virus was first discovered almost 70 years ago in Uganda. The first isolate of the virus was found in rhesus monkeys in the Zika Forrest, hence the nomenclature. The primary route of ZIKV transmission to humans is through the bite of an infected Aedes species mosquito-primarily Aedes aegypti...
November 9, 2016: Journal for Specialists in Pediatric Nursing: JSPN
https://www.readbyqxmd.com/read/27596229/similar-impact-of-multiple-sclerosis-and-migraine-on-sexual-function-in-women-is-the-multiple-sclerosis-impact-scale-questionnaire-useful
#2
Sabine Salhofer-Polanyi, Christian Wöber, Ricarda Prohazka, Assunta Dal-Bianco, Barbara Bajer-Kornek, Karin Zebenholzer
BACKGROUND: Sexuality is an integral part of overall health but the impact of neurological diseases on sexual function still receives too little attention. AIM: The aim of this case control study was to compare frequencies and characteristics of sexual dysfunction in women with stable relapsing-remitting multiple sclerosis (MS) and migraine. METHODS: Sexually active women aged 18-50 years were recruited at the MS and headache outpatient clinics of a university hospital and asked to complete questionnaires on sexual function using the multiple sclerosis intimacy and sexuality questionnaire (MSISQ-19) adapted for patients with migraine, depression using the Beck depression inventory (BDI-II) and quality of life using the short form-36 questionnaire (SF-36)...
September 5, 2016: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/27149205/update-ongoing-zika-virus-transmission-puerto-rico-november-1-2015-april-14-2016
#3
Emilio Dirlikov, Kyle R Ryff, Jomil Torres-Aponte, Dana L Thomas, Janice Perez-Padilla, Jorge Munoz-Jordan, Elba V Caraballo, Myriam Garcia, Marangely Olivero Segarra, Graciela Malave, Regina M Simeone, Carrie K Shapiro-Mendoza, Lourdes Romero Reyes, Francisco Alvarado-Ramy, Angela F Harris, Aidsa Rivera, Chelsea G Major, Marrielle Mayshack, Luisa I Alvarado, Audrey Lenhart, Miguel Valencia-Prado, Steve Waterman, Tyler M Sharp, Brenda Rivera-Garcia
Zika virus is a flavivirus transmitted primarily by Aedes species mosquitoes, and symptoms of infection can include rash, fever, arthralgia, and conjunctivitis (1).* Zika virus infection during pregnancy is a cause of microcephaly and other severe brain defects (2). Infection has also been associated with Guillain-Barré syndrome (3). In December 2015, Puerto Rico became the first U.S. jurisdiction to report local transmission of Zika virus, with the index patient reporting symptom onset on November 23, 2015 (4)...
2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27114196/efficacy-and-safety-of-sildenafil-by-age-in-men-with-erectile-dysfunction
#4
Irwin Goldstein, Li-Jung Tseng, Dana Creanga, Vera Stecher, Jed C Kaminetsky
INTRODUCTION: Sildenafil, an oral phosphodiesterase type 5 inhibitor, has been extensively investigated for the treatment of erectile dysfunction in randomized controlled trials. AIM: To assess the efficacy and safety of sildenafil vs placebo according to age subgroups (<65, 65-74, and ≥75 years) in 11,364 men with erectile dysfunction using pooled data from 48 randomized, double-blinded, placebo-controlled, parallel-group, flexible-dose trials. METHODS: Most trials had a 12-week treatment duration...
May 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27059507/combined-hormonal-contraception-use-in-reproductive-age-women-with-contraindications-to-estrogen-use
#5
Julianne R Lauring, Erik B Lehman, Timothy A Deimling, Richard S Legro, Cynthia H Chuang
BACKGROUND: The Centers for Disease Control and Prevention's US Medical Eligibility Criteria for Contraceptive Use recommends that combined hormonal contraceptives (ie, birth control pills, contraceptive patch, vaginal ring) should be avoided in women with specific medical conditions because of the increased risk of cardiovascular events associated with estrogen use. Whether women with category 3 (theoretical or proven risk usually outweigh the advantages) or category 4 (unacceptable health risk) contraindications are appropriately avoiding estrogen-containing combined hormonal contraceptives is unknown...
September 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27015869/the-typical-thunderclap-headache-of-reversible-cerebral-vasoconstriction-syndrome-and-its-various-triggers
#6
REVIEW
Anne Ducros, Valérie Wolff
During the last 10 years, reversible cerebral vasoconstriction syndrome (RCVS) has emerged as the most frequent cause of thunderclap headache (TCH) in patients without aneurysmal subarachnoid hemorrhage, and as the most frequent cause of recurrent TCHs. The typical TCHs of RCVS are multiple, recurring over a few days to weeks, excruciating, short-lived, and brought up by exertion, sexual activities, emotion, Valsalva maneuvers, or bathing, among other triggers. All these triggers induce sympathetic activation...
April 2016: Headache
https://www.readbyqxmd.com/read/26857820/european-headache-federation-consensus-on-technical-investigation-for-primary-headache-disorders
#7
D D Mitsikostas, M Ashina, A Craven, H C Diener, P J Goadsby, M D Ferrari, C Lampl, K Paemeleire, J Pascual, A Siva, J Olesen, V Osipova, P Martelletti
The diagnosis of primary headache disorders is clinical and based on the diagnostic criteria of the International Headache Society (ICHD-3-beta). However several brain conditions may mimic primary headache disorders and laboratory investigation may be needed. This necessity occurs when the treating physician doubts for the primary origin of headache. Features that represent a warning for a possible underlying disorder causing the headache are new onset headache, change in previously stable headache pattern, headache that abruptly reaches the peak level, headache that changes with posture, headache awakening the patient, or precipitated by physical activity or Valsalva manoeuvre, first onset of headache ≥50 years of age, neurological symptoms or signs, trauma, fever, seizures, history of malignancy, history of HIV or active infections, and prior history of stroke or intracranial bleeding...
2015: Journal of Headache and Pain
https://www.readbyqxmd.com/read/26746209/nausea-as-a-sentinel-symptom-for-cytotoxic-chemotherapy-effects-on-the-gut-brain-axis-among-women-receiving-treatment-for-recurrent-ovarian-cancer-an-exploratory-analysis
#8
Heidi S Donovan, Teresa L Hagan, Grace B Campbell, Michelle M Boisen, Leah M Rosenblum, Robert P Edwards, Dana H Bovbjerg, Charles C Horn
PURPOSE: Nausea is a common and potentially serious effect of cytotoxic chemotherapy for recurrent ovarian cancer and may function as a sentinel symptom reflecting adverse effects on the gut-brain axis (GBA) more generally, but research is scant. As a first exploratory test of this GBA hypothesis, we compared women reporting nausea to women not reporting nausea with regard to the severity of other commonly reported symptoms in this patient population. METHODS: A secondary analysis of data systematically collected from women in active chemotherapy treatment for recurrent ovarian cancer (n = 158) was conducted...
June 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/26692108/functional-gonadotroph-adenomas-case-series-and-report-of-literature
#9
David J Cote, Timothy R Smith, Courtney N Sandler, Tina Gupta, Tejus A Bale, Wenya Linda Bi, Ian F Dunn, Umberto De Girolami, Whitney W Woodmansee, Ursula B Kaiser, Edward R Laws
BACKGROUND: Functional gonadotroph adenomas (FGAs) are rare tumors of the pituitary gland that secrete biologically active gonadotropins. OBJECTIVE: To advance clinical understanding of FGAs. METHODS: We performed a retrospective review of adult patients who underwent resection of a pituitary lesion between August 1997 and October 2014 and remain under care at our center. We identified patients who had pathologic and biochemical confirmation of FGAs, as defined by a lack of serum follicle-stimulating hormone/luteinizing hormone suppression in the setting of elevated gonadal steroids, associated clinical symptoms, or both...
December 2016: Neurosurgery
https://www.readbyqxmd.com/read/26675022/-the-clinical-characteristics-of-twenty-five-cases-of-acute-hiv-1-infection-in-china
#10
Ning Li, Fuping Guo, Guanqun Li, Yang Han, Jing Xie, Yanling Li, Ting Zhu, Taisheng Li
OBJECTIVE: To summarize the clinical features, immunological and virological characteristics of HIV-1 infected patients in the acute phase for the sake of improving the understanding of acute HIV-1 infection and early diagnosis. METHODS: To retrospectively analyze the clinical manifestation and laboratory data of 25 patients with acute HIV infection, who were admitted to the Department of Infectious Diseases, Peking Union Medical College Hospital from 2006 to 2013...
October 2015: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/26518150/young-adults-with-headaches-the-transition-from-adolescents-to-adults
#11
Hope L O'Brien, Joshua M Cohen
Migraine is a common condition that for many begins in childhood and may progress over the course of one's life. The transition from adolescence to adulthood is a critical time for those who suffer from migraine and can be marked by a variety of important considerations for the patient and practitioner. Medication choices may be a challenge during adolescent years as Food and Drug Administration (FDA) approved options are few and many more studies are needed to understand the benefits and risks of use of these agents in adolescents...
November 2015: Headache
https://www.readbyqxmd.com/read/26480224/mental-health-and-sexual-activity-according-to-ancient-greek-physicians
#12
K Laios, G Tsoucalas, Μ-Ι Kontaxaki, Μ Karamanou, Μ Sgantzos, G Androutsos
The ancient Greek physicians have not failed in their studies to indicate the beneficial role of sexual activity in human health. They acknowledged that sex helps to maintain mental balance. Very interesting is their observation that sex may help mental patients to recover. Nevertheless they stressed emphatically that sex is beneficial only when there is a measure in it, so they believed that sexual abstinence or excessive sexual activity affect negatively the mental and physical health of man. Ancient Greek physicians reached this conclusion by empirical observation...
July 2015: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/26466691/prevalence-and-clinical-hallmarks-of-primary-exercise-headache-in-middle-aged-japanese-on-health-check-up
#13
Sayori Hanashiro, Takanori Takazawa, Yuji Kawase, Ken Ikeda
Objective We examined the prevalence and clinical features of primary exercise headache (PEH) in middle-aged Japanese population. Methods A headache specialist interviewed middle-aged subjects serially on health check-up. The primary headaches were diagnosed according to the International Classification of Headache Disorders (ICHD-III beta). Cardiovascular disease (CVD) risk and radiological findings were analyzed. Prevalence of PEH and clinical features were assessed. Results Among 2,546 subjects (1,588 men and 958 women), thirty subjects (13 men and 17 women) were diagnosed with PEH...
2015: Internal Medicine
https://www.readbyqxmd.com/read/26035186/a-randomized-double-blind-placebo-controlled-study-of-the-efficacy-and-safety-of-2-doses-of-vortioxetine-in-adults-with-major-depressive-disorder
#14
RANDOMIZED CONTROLLED TRIAL
Atul R Mahableshwarkar, Paula L Jacobsen, Michael Serenko, Yinzhong Chen, Madhukar H Trivedi
BACKGROUND: This 8-week, randomized, double-blind, placebo-controlled study, conducted August 2010-May 2012 in the United States, evaluated the safety and efficacy of vortioxetine 10 mg and 15 mg in patients with major depressive disorder (MDD). The mechanism of action of vortioxetine is thought to be related to direct modulation of serotonin (5-HT) receptor activity and inhibition of the serotonin transporter. METHOD: Adults aged 18-75 years with MDD (DSM-IV-TR) and Montgomery-Asberg Depression Rating Scale (MADRS) total score ≥ 26 were randomized (1:1:1) to receive vortioxetine 10 mg or 15 mg or placebo once daily, with the primary efficacy end point being change from baseline at week 8 in MADRS analyzed by mixed model for repeated measures...
May 2015: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/26001959/diurnal-cortisol-rhythm-associated-with-anxiety-and-depression-or-just-an-indication-of-lack-of-energy
#15
Anette Harris, Silje Endresen Reme, Tone Tangen, Åse Marie Hansen, Anne Helene Garde, Hege Randi Eriksen
Dysregulation of hypothalamus-pituitary-adrenal-activity has been associated with low back pain (LBP). The underlying mechanisms are not fully explained, but psychological mechanisms are considered important. In this study we examine the association between psychiatric disorders/symptoms measured with different instruments, and cortisol in a population with LBP. Participants (n=305) sick-listed 2-10 months due to non-specific LBP were included in the study. The screening instruments were the MINI-interview, HADS and HSCL-25...
August 15, 2015: Psychiatry Research
https://www.readbyqxmd.com/read/25985355/a-comprehensive-review-on-the-phytochemical-constituents-and-pharmacological-activities-of-pogostemon-cablin-benth-an-aromatic-medicinal-plant-of-industrial-importance
#16
REVIEW
Mallappa Kumara Swamy, Uma Rani Sinniah
Pogostemon cablin Benth. (patchouli) is an important herb which possesses many therapeutic properties and is widely used in the fragrance industries. In traditional medicinal practices, it is used to treat colds, headaches, fever, nausea, vomiting, diarrhea, abdominal pain, insect and snake bites. In aromatherapy, patchouli oil is used to relieve depression, stress, calm nerves, control appetite and to improve sexual interest. Till now more than 140 compounds, including terpenoids, phytosterols, flavonoids, organic acids, lignins, alkaloids, glycosides, alcohols, aldehydes have been isolated and identified from patchouli...
May 12, 2015: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/25788554/recurrence-of-reversible-cerebral-vasoconstriction-syndrome-a-long-term-follow-up-study
#17
Shih-Pin Chen, Jong-Ling Fuh, Jiing-Feng Lirng, Yen-Feng Wang, Shuu-Jiun Wang
OBJECTIVE: We aimed to investigate whether reversible cerebral vasoconstriction syndrome (RCVS) could recur and to identify the potential predictors of recurrence in a large cohort of patients. METHODS: This study followed a cohort of 210 patients with RCVS in a hospital-based headache center from 2000 to 2012. All patients were regularly followed up by telephone after remission for RCVS and were particularly asked to return to our hospital immediately if they developed new acute, severe (i...
April 14, 2015: Neurology
https://www.readbyqxmd.com/read/25583591/-changes-introduced-into-the-recent-international-classification-of-headache-disorders-ichd-iii-beta-classification
#18
Robert Belvis, Natàlia Mas, Carles Roig
INTRODUCTION: The International Headache Society (IHS) has published the third edition of the International Classification of Headache Disorders (ICHD-III beta), the most commonly used guide to diagnosing headaches in the world. AIMS: To review the recent additions to the guide, to explain the new entities that appear in it and to compare the conditions that have had their criteria further clarified against the criteria in the previous edition. DEVELOPMENT: We have recorded a large number of clarifications in the criteria in practically all the headaches and neuralgias in the classification, but the conditions that have undergone the most significant clarifications are chronic migraine, primary headache associated with sexual activity, short-lasting unilateral neuralgiform headache attacks, new daily persistent headache, medication-overuse headache, syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis...
January 16, 2015: Revista de Neurologia
https://www.readbyqxmd.com/read/25575488/a-randomized-double-blind-duloxetine-referenced-study-comparing-efficacy-and-tolerability-of-2-fixed-doses-of-vortioxetine-in-the-acute-treatment-of-adults-with-mdd
#19
RANDOMIZED CONTROLLED TRIAL
Atul R Mahableshwarkar, Paula L Jacobsen, Yinzhong Chen, Michael Serenko, Madhukar H Trivedi
RATIONALE: Vortioxetine has reduced depressive symptoms in adults with major depressive disorder (MDD) in multiple clinical trials. OBJECTIVES: The aim of this study is to evaluate the efficacy, safety, and tolerability of vortioxetine 15 and 20 mg vs placebo in adults with MDD. METHODS: Patients were randomized 1:1:1:1 to vortioxetine 15 mg, vortioxetine 20 mg, duloxetine 60 mg (active reference), or placebo. The primary efficacy endpoint was mean change in Montgomery-Åsberg Depression Rating Scale (MADRS) total score at week 8 (MMRM)...
June 2015: Psychopharmacology
https://www.readbyqxmd.com/read/25395707/medicinal-plants-used-as-home-remedies-a-family-survey-by-first-year-medical-students
#20
Constance R Sewani-Rusike, Marykutty Mammen
BACKGROUND: There is a hierarchical organisation of knowledge in the use of medicinal plants in communities. Medicinal use knowledge starts in the home and is passed on to family members. Next in the hierarchy are neighbours, village elders and finally, traditional healers being the most knowledgeable. For primary health care this hierarchy is actively followed in seeking remedies for ailments. MATERIALS AND METHODS: This study was a survey of medicinal plant knowledge from family members of 1(st) year medical students registered at Walter Sisulu University...
2014: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
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