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https://www.readbyqxmd.com/read/29868521/measuring-near-infrared-spectroscopy-derived-cerebral-autoregulation-in-neonates-from-research-tool-toward-bedside-multimodal-monitoring
#1
REVIEW
Liesbeth Thewissen, Alexander Caicedo, Petra Lemmers, Frank Van Bel, Sabine Van Huffel, Gunnar Naulaers
Introduction: Cerebral autoregulation (CAR), the ability of the human body to maintain cerebral blood flow (CBF) in a wide range of perfusion pressures, can be calculated by describing the relation between arterial blood pressure (ABP) and cerebral oxygen saturation measured by near-infrared spectroscopy (NIRS). In literature, disturbed CAR is described in different patient groups, using multiple measurement techniques and mathematical models. Furthermore, it is unclear to what extent cerebral pathology and outcome can be explained by impaired CAR...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29859395/determination-of-reference-intervals-for-umbilical-cord-arterial-and-venous-blood-gas-analysis-of-healthy-thoroughbred-foals
#2
Sunita S Jeawon, Lisa M Katz, Noreen P Galvin, Ursula M Fogarty, Vivienne E Duggan
Although umbilical cord blood gas analysis is considered the best way to assess in utero oxygenation in human neonates, there is limited evaluation of this method in equine neonatology. Our objectives were to assess the practicality of obtaining umbilical cord blood gas samples in the field and to determine umbilical cord arterial and venous blood gas reference intervals (RI) for healthy, newborn foals. Thoroughbred foals >320 days gestation from healthy mares with uneventful pregnancies at one stud farm were evaluated...
May 25, 2018: Theriogenology
https://www.readbyqxmd.com/read/29852486/title-page-sharing-progress-in-neonatology-spin-moving-towards-individualized-prenatal-and-neonatal-care
#3
(no author information available yet)
No abstract text is available yet for this article.
2018: Neonatology
https://www.readbyqxmd.com/read/29852485/sharing-progress-in-neonatology-spin-moving-towards-individualized-prenatal-and-neonatal-care
#4
Egbert Herting, Tore Curstedt, Henry L Halliday, Mikko Hallman, Ola D Saugstad, Christian P Speer
No abstract text is available yet for this article.
2018: Neonatology
https://www.readbyqxmd.com/read/29852484/clinical-metabolomics-in-neonatology-from-metabolites-to-diseases
#5
Vassilios Fanos, Roberta Pintus, Angelica Dessì
Today, disorders that affect the newborn remain a challenge for physicians because of the enigmatic pathophysiology and difficulties in treating such delicate patients. Metabolomics, the "omics" science that studies the metabolome, namely the metabolites present in biological fluids, such as saliva, blood, sweat, and breast milk in a given time or condition, can be useful in helping neonatologists to prevent, diagnose, and treat diseases affecting the neonate, especially those with higher mortality rates...
2018: Neonatology
https://www.readbyqxmd.com/read/29852483/abstracts-sharing-progress-in-neonatology-spin-moving-towards-individualized-prenatal-and-neonatal-care
#6
(no author information available yet)
No abstract text is available yet for this article.
2018: Neonatology
https://www.readbyqxmd.com/read/29802805/how-many-procedures-do-uk-paediatric-trainees-perform-in-their-neonatal-posts
#7
Sridhar M Ramaiah, Naveen Athiraman, Yincent Tse
The UK training programme typically takes 8 years full time equivalent to become a paediatric consultant but can be shortened to as little as five years if deemed competent. At minimum trainees complete two six months posts in neonatology, one at level 1 Specialty training (ST 1-3) and another at level 2 training (ST 4-5) during their paediatric training programme. According to the Royal College of Paediatrics and Child Health curriculum (1), by end of ST 5 training year the competent paediatric registrar will 'be able to provide and lead basic and advanced neonatal resuscitation' and 'be able to intubate sick newborn infants without direct supervision...
May 26, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29799887/-thyroid-hormone-levels-in-very-preterm-neonates-and-extremely-preterm
#8
Carlos Kilchemmann F, Andrés Román N, Marcela Navarrete R, Denisse Fuentes B
INTRODUCTION: The thyroid function of the pretern infant is altered by the relative immaturity of the hypothalamus-pituitary thyroid gland axis, along with other factors such as the incidence of diseases or the use of some drugs. Currently, there is controversy over normal levels of free thyroxine (FT4) in preterm infants. Our objective was to determine the distribution of FT4 and TSH values in newborn younger than 32 weeks or 1500 g of birth weight at 15 days of chronological age, in the neonatology service at Dr...
April 2018: Revista Chilena de Pediatría
https://www.readbyqxmd.com/read/29782437/skin-injuries-and-chlorhexidine-gluconate-based-antisepsis-in-early-premature-infants-a-case-report-and-review-of-the-literature
#9
Valentina Vanzi, Rosanna Pitaro
Early premature infants are subjected to many invasive procedures in neonatal intensive care units, and effective skin antisepsis is an essential step in caring for these vulnerable patients. Nevertheless, preterm infants have an anatomically and physiologically immature skin and preserving their skin integrity is essential to avoid the risk of local and systemic complications. Skin particularities of newborns reduce the list of available antiseptics in neonatology. Chlorhexidine gluconate (CHG) has excellent antiseptic properties and its antimicrobial efficacy cannot be understated, but there is great concern about its use for premature infants, referring to the risk of development skin injuries, such as skin erythema, burns, and blisters...
May 17, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29761674/screening-arab-israeli-pregnant-women-for-group-b-streptococcus-by-the-amplivue-gbs-assay-are-the-rates-higher-than-the-national-average
#10
Marwan Hakim, Adel Jabour, Miriam Anton, Meggie Hakim, Sahar Kheirallah
BACKGROUND: The recommendation of the U.S. Centers for Disease Control and Prevention regarding universal screening for Group B Streptococcus (GBS) at 35-37 weeks gestational age in pregnancy is not accepted in Israel. The National Council for Obstetrics, Neonatology and Genetics recommends intrapartum prophylaxis, mainly based on risk factors, to prevent early neonatal GBS infection. This policy is based on past studies demonstrating low colonization rates of the bacteria in Israeli pregnant women and very low neonatal sepsis rates...
May 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29754867/assessing-ethics-knowledge-development-of-a-test-of-ethics-knowledge-in-neonatology
#11
Christy L Cummings, Gina M Geis, Henry A Feldman, Elisa R Berson, Jennifer C Kesselheim
OBJECTIVE: To develop and validate the Test of Ethics Knowledge in Neonatology (TEK-Neo) with good internal consistency reliability, item performance, and construct validity that reliably assesses interprofessional staff and trainee knowledge of neonatal ethics. STUDY DESIGN: We adapted a published test of ethics knowledge for use in neonatology. The novel instrument had 46 true/false questions distributed among 7 domains of neonatal ethics: ethical principles, professionalism, genetic testing, beginning of life/viability, end of life, informed permission/decision making, and research ethics...
May 10, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29737005/2017-pediatric-pulmonology-year-in-review-part-2-neonatology
#12
Richard L Auten
The articles published in 2017 in topic areas relevant to neonatal pulmonology are reviewed in Part 2 of the Year-in-Review.
May 7, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29725040/membrane-depolarization-and-aberrant-lipid-distributions-in-the-neonatal-rat-brain-following-hypoxic-ischaemic-insult
#13
Dominika Luptakova, Ladislav Baciak, Tomas Pluhacek, Anton Skriba, Blanka Sediva, Vladimir Havlicek, Ivo Juranek
Neonatal hypoxic-ischaemic (HI) encephalopathy is among the most serious complications in neonatology. In the present study, we studied the immediate (0 hour), subacute (36 hours) and late (144 hours) responses of the neonatal brain to experimental HI insult in laboratory rats. At the striatal level, the mass spectrometry imaging revealed an aberrant plasma membrane distribution of Na+ /K+ ions in the oedema-affected areas. The failure of the Na+ /K+ gradients was also apparent in the magnetic resonance imaging measurements, demonstrating intracellular water accumulation during the acute phase of the HI insult...
May 3, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29723237/association-of-maternal-nutrition-with-transient-neonatal-hyperinsulinism
#14
Mathilde Louvigne, Stephanie Rouleau, Emmanuelle Caldagues, Isabelle Souto, Yanis Montcho, Audrey Migraine Bouvagnet, Olivier Baud, Jean Claude Carel, Geraldine Gascoin, Regis Coutant
OBJECTIVE: The objective was to determine whether maternal nutritional factors are associated with transient neonatal hyperinsulinism (HI). DESIGN AND SETTING: Case control study in 4 French tertiary Obstetrics and Neonatology Departments between 2008 and 2015. METHODS: Sixty-seven mothers of neonates diagnosed with transient hyperinsulinism and 113 mothers of controls were included. The screening for hyperinsulinemic hypoglycemia in neonates was performed because of clinical symptoms suggestive of hypoglycemia or in the presence of conventional risk factors (small-for-gestational-age, prematurity, anoxo-ischemia, hypothermia, macrosomia, gestational diabetes)...
2018: PloS One
https://www.readbyqxmd.com/read/29721741/off-label-and-unlicensed-drug-use-in-hospitalized-newborns-in-a-saudi-tertiary-care-hospital-a-cohort-study
#15
Faizan Mazhar, Shahzad Akram, Nafis Haider, Muhammad Abdul Hadi, Jabeen Sultana
Objective To determine the extent of off-label and unlicensed prescribing in hospitalized newborns and to identify patient-related risk factors associated with off-label prescribing. Methods A prospective cohort study was conducted between January and March 2016 at a neonatology department of a tertiary-care hospital in the Eastern province. All consecutive admissions to all neonatal care levels meeting the inclusion and exclusion criteria were eligible for enrollment. All prescriptions were classified as off-label or unlicensed according to drug product monograph...
May 2, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29706798/rooming-in-reduces-salivary-cortisol-level-of-newborn
#16
Giuseppe De Bernardo, Marina Riccitelli, Maurizio Giordano, Fabrizio Proietti, Desiree Sordino, Mariangela Longini, Giuseppe Buonocore, Serafina Perrone
Background: Rooming-in practice improves breastfeeding and reduces newborn stress reactivity. When this modality is not available, partial rooming-in after birth can be considered. Salivary cortisol levels (SCLs) are considered reliable biomarkers to indicate stress. Objective: To test the hypothesis that rooming-in duration impacts neonatal stress response in hospitalized newborns. Design/methods: Forty term newborns, enrolled in the Neonatology and Obstetrics Nursing, C...
2018: Mediators of Inflammation
https://www.readbyqxmd.com/read/29693575/maternal-vaccination-as-an-essential-component-of-life-course-immunization-and-its-contribution-to-preventive-neonatology
#17
REVIEW
Naomi Bergin, Janice Murtagh, Roy K Philip
Maternal immunisation schedules are increasingly coming under the spotlight as part of the development of lifetime immunisation programmes for the role that they play in improving maternal, foetal, and neonatal health. Maternally-acquired antibodies are critical in protecting infants during the first months of their lives. Maternal immunisation was previously overlooked owing to concerns regarding vaccinations in this untested and high-risk population but is now acknowledged for its potential impact on the outcomes in many domains of foetal and neonatal health, aside from its maternal benefits...
April 25, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29688648/-teaching-resuscitation-skills-on-a-newly-dead-infant
#18
Shaul Dollberg, Michael Y Barilan
Trainees in pediatrics and neonatology have to learn and remain updated regarding current lifesaving intubation procedures. The decrease in clinical indications for neonatal intubation limits their ability to practice and perfect procedures. Alternative methods for training, e.g., the use of manikins, do not satisfy the intended goal. Legitimization of the use of newly deceased infants for practice purposes is morally acceptable and may save lives. The requirement of mandatory parental consent for this type of training may result in reduced resuscitation capabilities and in loss of lives...
April 2018: Harefuah
https://www.readbyqxmd.com/read/29678190/neonatal-and-congenital-malaria-a-case-series-in-malaria-endemic-eastern-uganda
#19
Peter Olupot-Olupot, Emma I E Eregu, Ketty Naizuli, Julie Ikiror, Linda Acom, Kathy Burgoine
BACKGROUND: Congenital malaria is the direct infection of an infant with malaria parasites from their mother prior to or during birth. Neonatal malaria is due to an infective mosquito bite after birth. Neonatal and congenital malaria (NCM) are potentially life-threatening conditions that are believed to occur at relatively low rates in malaria endemic regions. However, recent reports suggest that the number of NCM cases is increasing, and its epidemiology remains poorly described. NCM can mimic other neonatal conditions and because it is thought to be rare, blood film examinations for malaria are not always routinely performed...
April 20, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29664875/do-not-resuscitate-orders-in-the-neonatal-icu-experiences-and-beliefs-among-staff
#20
Bonnie H Arzuaga, C Lydia Wraight, Christy L Cummings, Wenyang Mao, David Miedema, Dara D Brodsky
OBJECTIVES: Studies in adult patients have shown that do-not-resuscitate orders are often associated with decreased medical intervention. In neonatology, this phenomenon has not been investigated, and how do-not-resuscitate orders potentially affect clinical care is unknown. DESIGN: Retrospective medical record data review and staff survey responses about neonatal ICU do-not-resuscitate orders. SETTING: Four academic neonatal ICUs. SUBJECTS: Clinical staff members working in each neonatal ICU...
April 16, 2018: Pediatric Critical Care Medicine
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