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Florence Bonkain, Judith Racapé, Isabelle Goncalvez, Micheline Moerman, Olivier Denis, Nadia Gammar, Karine Gastaldello, Joëlle L Nortier
BACKGROUND: Hemodialysis (HD) tunneled cuffed catheters may be fitted with neutral-valve closed-system connectors. Such connectors, which are flushed with saline solution and used for 3 consecutive HD sessions, provide a mechanically closed positive-pressure barrier and potentially may be useful to prevent catheter-related bacteremia and dysfunction. STUDY DESIGN: Single-center randomized controlled trial. SETTING & PARTICIPANTS: 66 adult HD patients with a tunneled cuffed catheter...
March 2013: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Georgia Winnett, Jonathan Nolan, Michael Miller, Neil Ashman
BACKGROUND: Trisodium citrate (TSC) 30% has been shown in a randomized control trial to be an effective antimicrobial catheter locking solution, able to significantly reduce catheter-related bacteraemia (CRB) in haemodialysis patients. Since that report, the formulation in Europe has been changed to 46.7% TSC without confirmatory data on efficacy. We report a 55 915 patient-day at risk experience in tunnelled lines of 46.7% TSC, emphasizing efficacy and changes in microbiology seen. METHODS: On 1 July 2006, inter-dialytic catheter locking solution was changed from 5000 IU/ml heparin to Citra-lock(TM) (46...
November 2008: Nephrology, Dialysis, Transplantation
Cornelius J Doorenbos, Marjo Van den Elsen-Hutten, Margret J M Heuven, Jan Hessels
No abstract text is available yet for this article.
February 2006: Nephrology, Dialysis, Transplantation
R Srivastava, M J Murphy, J Card, A Severn, C G Fraser
In patients with chronic renal failure, blood samples for laboratory analysis are often taken via dialysis catheters. This report describes a case of gross spurious hypernatraemia in a blood sample collected from a patient undergoing haemodialysis. After centrifugation of the blood sample in question, the separator gel formed the topmost layer, with the serum in the middle and the clot at the bottom. Subsequent analysis of the serum showed severe hypernatraemia (serum sodium, 744 mmol/litre). It was established that the blood sample had been taken from the patient's dialysis catheter into which 3 ml of Citra-Lock (46...
December 2004: Journal of Clinical Pathology
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