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https://www.readbyqxmd.com/read/29228288/outcome-measures-used-in-pulmonary-rehabilitation-in-patients-with-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-a-systematic-review
#1
Ana L Oliveira, Alda S Marques
Background: Conflicting results about the effects of community-based pulmonary rehabilitation in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) exist, possibly because the variety of outcome measures used and the lack of appropriate measurement properties hinder the development of pulmonary rehabilitation guidelines. Purpose: The purpose of this study was to identify and review the measurement properties of patient-reported outcome measures (PROMs) and clinical outcome measures of AECOPD that are used in pulmonary rehabilitation and that can be easily applied in a community setting...
December 6, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29227938/the-cumulative-effect-of-air-pollutants-on-the-acute-exacerbation-of-copd-in-shanghai-china
#2
Xian Wen Sun, Pei Li Chen, Lei Ren, Ying Ni Lin, Jian Ping Zhou, Lei Ni, Qing Yun Li
BACKGROUND: Epidemiologic studies have shown the effect of air pollutants on acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, little is known regarding the dose-response relationship. This study aimed to investigate the cumulative effect of air pollutants on AECOPD. METHODS: We collected 101 patients with AECOPD from November 2010 through August 2011 in Shanghai. Multiple logistic regression was used to estimate associations between air pollutants and AECOPD...
December 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29227849/associations-between-long-term-pm2-5-and-ozone-exposure-and-mortality-in-the-canadian-census-health-and-environment-cohort-canchec-by-spatial-synoptic-classification-zone
#3
Sabit Cakmak, Chris Hebbern, Lauren Pinault, Eric Lavigne, Jennifer Vanos, Dan Lawson Crouse, Michael Tjepkema
Studies suggest that long-term chronic exposure to fine particulate matter air pollution can increase lung cancer mortality. We analyzed the association between long term PM2.5 and ozone exposure and mortality due to lung cancer, ischemic heart disease, and chronic obstructive pulmonary disease, accounting for geographic location, socioeconomic status, and residential mobility. Subjects in the 1991 Canadian Census Health and Environment Cohort (CanCHEC) were followed for 20years, and assigned to regions across Canada based on spatial synoptic classification weather types...
December 8, 2017: Environment International
https://www.readbyqxmd.com/read/29227717/quercetin-restores-corticosteroid-sensitivity-in-cells-from-patients-with-chronic-obstructive-pulmonary-disease
#4
Akihisa Mitani, Aishah Azam, Chaitanya Vuppusetty, Kazuhiro Ito, Nicolas Mercado, Peter J Barnes
Corticosteroid resistance is a major barrier to the effective treatment of chronic obstructive pulmonary disease (COPD). Oxidative stress from cigarette smoke and chronic inflammation is likely to induce this corticosteroid insensitivity. Quercetin is a polyphenol that has been reported to be an active oxygen scavenger as well as a functional adenosine monophosphate-activated protein kinase (AMPK) activator. The aim of this study was to investigate the effect of quercetin on corticosteroid responsiveness in COPD cells...
December 11, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/29227712/a-comparison-of-pain-fatigue-dyspnea-and-their-impact-on-quality-of-life-in-pulmonary-rehabilitation-participants-with-chronic-obstructive-pulmonary-disease
#5
Yi-Wen Chen, Pat G Camp, Harvey O Coxson, Jeremy D Road, Jordan A Guenette, Michael A Hunt, W Darlene Reid
In addition to dyspnea and fatigue, pain is a prevalent symptom in chronic obstructive pulmonary disease (COPD). Understanding the relative prevalence, magnitude, and interference with aspects of daily living of these symptoms can improve COPD management. Therefore, the purposes of this study were to: (1) compare the prevalence and magnitude of dyspnea, fatigue, and pain and how each limits aspects of daily living; (2) determine the association between pain and the other two symptoms; and (3) assess the impact of these symptoms on quality of life in COPD...
December 11, 2017: COPD
https://www.readbyqxmd.com/read/29227362/comorbidity-of-airway-inflammatory-diseases-in-chemical-and-building-related-intolerance
#6
Anna-Sara Claeson, Hanna Andersson, Fredrik Wikdahl, Maj-Helen Nyback, Steven Nordin
OBJECTIVES: This study investigated comorbidity in chemical intolerance (CI) and building- related intolerance (BRI) with (i) chronic sinusitis, chronic obstructive pulmonary disease, allergic and non-allergic asthma and allergic rhinitis, and (ii) airway inflammatory symptoms. METHODS: Data from two population-based questionnaire surveys, the Västerbotten and Österbotten Environmental Health Studies was used. The participants were categorized as CI or BRI and referents, and binary logistic regression analysis was applied...
December 8, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29227305/lung-transplantation-for-chronic-obstructive-pulmonary-disease-past-present-and-future-directions
#7
Faisal M Siddiqui, Joshua M Diamond
PURPOSE OF REVIEW: Lung transplantation offers an effective treatment modality for patients with end-stage chronic obstructive pulmonary disease (COPD). The exact determination of when to refer, list, and offer transplant as well as the preferred transplant procedure type remains unclear. Additionally, there are special considerations specific to patients with COPD being considered for lung transplantation, including the implications of single lung transplantation on lung cancer risk, native lung hyperinflation, and overall survival...
December 7, 2017: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/29227032/efficacy-and-safety-of-low-dose-urokinase-for-the-treatment-of-hemodynamically-stable-aecopd-patients-with-acute-pulmonary-thromboembolism
#8
Xiaogang Jing, Guojun Zhang, Beifeng Zhang, Lingling Dai, Xi Wang, Liuqun Jia, Huan Wang, Lin An, Yuanjian Yang, Zhe Cheng
PURPOSE: To assess the incidence of pulmonary thromboembolism (PTE) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD), and to evaluate the efficacy and safety of low-dose urokinase (UK) thrombolysis therapy when treating hemodynamically stable AECOPD patients with acute PTE (AECOPD-PTE). METHODS: A total of 419 AECOPD patients, including 96 AECOPD-PTE, were enrolled. 30 AECOPD-PTE patients were collected retrospectively and 66 AECOPD-PTE patients were prospectively divided into anticoagulation-only, low-dose UK and standard-dose UK groups...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29227024/blood-biomarkers-as-predictors-of-long-term-mortality-in-copd
#9
Angelico Mendy, Erick Forno, Theophile Niyonsenga, Janvier Gasana
BACKGROUND: Blood biomarkers are easily accessible and might reflect chronic obstructive pulmonary disease (COPD) activity. AIM: To determine whether a panel of blood biomarkers (C-reactive protein [CRP], neutrophils, eosinophils, albumin and vitamin D) could predict mortality in COPD. METHODS: we analyzed data from 431 COPD participants to the 2007-2010 National Health and Nutrition Examination Surveys who were followed for a median time of 36 months...
December 11, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29226070/economic-burden-of-community-acquired-pneumonia-among-elderly-patients-a-japanese-perspective
#10
Keiko Konomura, Hideaki Nagai, Manabu Akazawa
Background: This study aimed to estimate the economic burden of community-acquired pneumonia (CAP) among elderly patients in Japan. In addition, the study evaluated the relationship between total treatment cost and CAP risk factors. Methods: An administrative database was searched for elderly patients (≥ 65 years old) who had pneumonia (ICD-10 code: J12-J18) and an antibiotic prescription between 1 June 2014 and 31 May 2015. The all-cause total healthcare costs of outpatient and inpatient CAP episodes were calculated...
2017: Pneumonia
https://www.readbyqxmd.com/read/29225775/fibromax-based-nonalcoholic-fatty-liver-disease-in-chronic-obstructive-pulmonary-disease-patients-with-obstructive-sleep-apnea-methodological-considerations
#11
Denis Monneret
The relationship between nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) has been well demonstrated, but remains to be evidenced in chronic obstructive pulmonary disease (COPD). Recently, Viglino et al. (Eur Respir J, 2017) attempted to determine the prevalence of liver fibrosis, steatosis and nonalcoholic steatohepatitis (NASH) in COPD patients, some of whom had OSA, basing the NAFLD diagnostic on three circulating biomarker-based liver scores: the FibroTest, SteatoTest and NashTest, from the Fibromax® panel...
2017: F1000Research
https://www.readbyqxmd.com/read/29225684/colon-cancer-presenting-as-pseudo-obstruction-during-pregnancy-a-case-report
#12
Reeva Makhijani, Vicky H Bhagat, Mariam Fayek
The incidence of colorectal cancer in pregnancy is between 0.002 and 0.008%. Diagnosis is often delayed as symptoms of colorectal cancer can mimic as common complaints of pregnancy. We present the case of a 29-year-old with a history of chronic constipation who presented in the second trimester with abdominal pain, inability to tolerate anything orally and no bowel movement in more than three weeks. Non-contrast MRI at presentation failed to show an obstructing mass. Patient was treated conservatively for presumed pseudo-obstruction secondary to worsening constipation from chronic ondansetron use and pregnancy...
December 2017: Obstetric Medicine
https://www.readbyqxmd.com/read/29224663/obstruction-of-the-biliary-and-urinary-system
#13
William O'Connell, Jay Shah, Jason Mitchell, J David Prologo, Louis Martin, Michael J Miller, Jonathan G Martin
Biliary and urinary obstructions can be managed endoscopically or cystoscopically, surgically or by percutansous intervention or drainage. If the obtructed system is infected, emergent decompression is needed. Early recognition and treatment is paramount in both conditions. Acute cholangitis can present many different ways, from mild symptoms to fulminant sepsis. It is usually a result of ascending bacterial colonization and biliary obstruction resulting in bacterial overgrowth. Therefore, those patients with recent biliary instrumentation or previous biliary modification are at higher risk...
December 2017: Techniques in Vascular and Interventional Radiology
https://www.readbyqxmd.com/read/29224640/return-to-the-workforce-following-infective-endocarditis-a-nationwide-cohort-study
#14
Jawad H Butt, Kristian Kragholm, Michael Dalager-Pedersen, Rasmus Rørth, Søren L Kristensen, Mavish S Chaudry, Nana Valeur, Lauge Østergaard, Christian Torp-Pedersen, Gunnar H Gislason, Lars Køber, Emil L Fosbøl
BACKGROUND: The ability to return to work after infective endocarditis (IE) holds important socioeconomic consequences for both patients and society, yet data on this issue are sparse. We examined return to the workforce and associated factors in IE patients of working age. METHODS: Using Danish nationwide registries, we identified 1,065 patients aged 18-60 years with a first-time diagnosis of IE (1996-2013) who were part of the workforce prior to admission and alive at discharge...
January 2018: American Heart Journal
https://www.readbyqxmd.com/read/29224305/-recent-advance-in-impacts-of-pulmonary-rehabilitation-on-inflammation-and-oxidative-stress-in-chronic-obstructive-pulmonary-disease
#15
B P Guo, L L Zhou, L L Guan
No abstract text is available yet for this article.
December 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29224299/-correlation-analysis-of-serum-secreted-frizzled-related-protein-5-levels-with-airway-inflammation-and-insulin-resistance-in-chronic-obstructive-pulmonary-disease-patients
#16
G Y Li, S J Yin, Y Liu, H Li, S Song, Z B Kong, C Zuo, H Liu, Z Zhu
Objective: To investigate the relationship between serum secreted frizzled-related protein 5(sfrp5) levels, insulin resistance, and airway inflammation in patients with chronic obstructive pulmonary disease(COPD). Method: A total of 178 COPD patients visiting our respiratory outpatient clinic from February 2015 to January 2017 were enrolled, and 99 healthy control subjects from the same time period were selected. Serum sfrp5 levels were compared between the 2 groups. Serum sfrp5 and inflammatory cytokines in induced sputum were observed in the 4 subgroups: insulin resistant COPD group [homeostasis model assessment of insulin resistance (HOMA-IR)≥2...
December 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29224293/-development-of-diagnosis-and-treatment-of-chronic-obstructive-pulmonary-disease-needs-participatory-and-personalized
#17
R C Chen
No abstract text is available yet for this article.
December 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29224257/models-of-care-for-non-invasive-ventilation-in-the-acute-copd-comparison-of-three-tertiary-hospitals-act3-study
#18
Kerry Parker, Vara Perikala, Ali Aminazad, Zheng Deng, Brigitte Borg, Catherine Buchan, Jo Toghill, Louis B Irving, Jeremy Goldin, David Charlesworth, Ajay Mahal, Suhith Illesinghe, Matthew T Naughton, Alan Young
BACKGROUND AND OBJECTIVE: Non-invasive ventilation (NIV) improves clinical outcomes in hypercapnic acute exacerbations of COPD (AECOPD), but the optimal model of care remains unknown. METHODS: We conducted a prospective observational non-inferiority study comparing three models of NIV care: general ward (Ward) (1:4 nurse to patient ratio, thrice weekly consultant ward round), a high dependency unit (HDU) (1:2 ratio, twice daily ward round) and an intensive care unit (ICU) (1:1 ratio, twice daily ward round) model in three similar teaching tertiary hospitals...
December 10, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/29224172/evaluation-of-clinical-risk-factors-for-osteoporosis-and-applicability-of-the-frax-tool-in-joinville-city-southern-brazil
#19
Dalisbor Marcelo Weber Silva, Victoria Zeghbi Cochenski Borba, John A Kanis
Clinical risk factors for fracture in Southern Brazil are similar to those used in Fracture Risk Assessment Tool (FRAX®). Age-dependent intervention thresholds had higher accuracy than a fixed cut-off point. INTRODUCTION: Access to bone mineral density testing is wanted for a large part of the Brazilian population. The FRAX® has an option to calculate the risk of fracture without this costly evaluation but relies on the clinical risk factors (CRFs) identified in the source cohorts used to generate FRAX...
December 9, 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/29224095/sex-differences-in-muscle-wasting
#20
Lindsey J Anderson, Haiming Liu, Jose M Garcia
With aging and other muscle wasting diseases, men and women undergo similar pathological changes in skeletal muscle: increased inflammation, enhanced oxidative stress, mitochondrial dysfunction, satellite cell senescence, elevated apoptosis and proteasome activity, and suppressed protein synthesis and myocyte regeneration. Decreased food intake and physical activity also indirectly contribute to muscle wasting. Sex hormones also play important roles in maintaining skeletal muscle homeostasis. Testosterone is a potent anabolic factor promoting muscle protein synthesis and muscular regeneration...
2017: Advances in Experimental Medicine and Biology
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