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https://www.readbyqxmd.com/read/28199764/clinical-markers-of-asthma-and-ige-assessed-in-parents-before-conception-predicts-asthma-and-hay-fever-in-the-offspring
#1
Randi J Bertelsen, Marta Rava, Anne Elie Carsin, Simone Accordini, Bryndis Benediktsdóttir, Julia Dratva, Karl A Franklin, Joachim Heinrich, Mathias Holm, Christer Janson, Ane Johannessen, Deborah L Jarvis, Rain Jogi, Benedicte Leynaert, Dan Norback, Ernst Reidar Omenaas, Chantal Raherison, José Luis Sánchez-Ramos, Vivi Schlünssen, Torben Sigsgaard, Shyamali C Dharmage, Cecilie Svanes
BACKGROUND: Mice models suggest epigenetic inheritance induced by parental allergic disease activity. However, we know little of how parental disease activity before conception influences offspring's asthma and allergy in humans. OBJECTIVE: We aimed to assess the associations of parental asthma severity, bronchial hyperresponsiveness (BHR), and total and specific IgEs, measured before conception vs after birth, with offspring asthma and hay fever. METHODS: The study included 4293 participants (mean age 34, 47% men) from the European Community Respiratory Health Survey (ECRHS) with information on asthma symptom severity, BHR, total and specific IgEs from 1991-1993, and data on 9100 offspring born 1972-2012...
February 15, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28179115/chemical-composition-of-the-essential-oils-and-extracts-of-achillea-species-and-their-biological-activities-a-review
#2
REVIEW
Majid Mohammadhosseini, Satyajit D Sarker, Abolfazl Akbarzadeh
ETHNOPHARMACOLOGICAL RELEVANCE: The Asteraceae (alt. Compositae) family incorporates a large number of flowering plants, which have been classified under ca. 1600 genera covering more than 23,000 species. The genus Achillea is one of the best-known genera of this family. The Achillea species are important for their uses in the chemical and pharmaceutical purposes, and traditional and folk medicines. From ethnobotanical point of view, they heve been recommended as effective tonic, sedative, diuretic and carminative remedies and extensively prescribed for the treatment of stomachache, inflammation, gastrointestinal, hemorrhoid, hay fever, and wound healing in indigenous medicines...
February 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28165640/significant-disparities-in-allergy-prevalence-and-microbiota-between-the-young-people-in-finnish-and-russian-karelia
#3
Lasse Ruokolainen, Laura Paalanen, Antti Karkman, Tiina Laatikainen, Leena von Hertzen, Tiina Vlasoff, Olga Markelova, Vladimir Masyuk, Petri Auvinen, Lars Paulin, Harri Alenius, Nanna Fyhrquist, Ilkka Hanski, Mika J Mäkelä, Elmira Zilber, Pekka Jousilahti, Erkki Vartiainen, Tari Haahtela
BACKGROUND: Atopic allergy has been more common among schoolchildren in Finland, as compared to Russian Karelia. These adjacent regions show one of the most contrasting socio-economically differences in the world. OBJECTIVE: We explored changes in allergy from school age to young adulthood from 2003 to 2010/2012 in these two areas. The skin and nasal microbiota were also compared. METHODS: Randomly selected children from Finnish (n = 98) and Russian Karelia (n = 82) were examined in 2003, when the children were 7-11 years of age, and again in 2010 (Finnish Karelia) and 2012 (Russian Karelia)...
February 6, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28140507/google-trends-terms-reporting-rhinitis-and-related-topics-differ-in-european-countries
#4
Jean Bousquet, Ioana Agache, Josep M Anto, Karl C Bergmann, Claus Bachert, Isabella Annesi-Maesano, Philippe J Bousquet, Gennaro D'Amato, Pascal Demoly, Govert De Vries, Esben Eller, Wytske Fokkens, Joao Fonseca, Tari Haahtela, Peter W Hellings, Jocelyne Just, Thomas Keil, Ludger Klimek, Piotr Kuna, Karin C Lodrup Carlsen, Ralf Mösges, Ruth Murray, Kristof Nekam, Gabrielle Onorato, Nikos G Papadopoulos, Boleslaw Samolinski, Peter Schmid-Grendelmeier, Michel Thibaudon, Peter Tomazic, Massimo Triggiani, Arunas Valiulis, Erkka Valovirta, Michiel Van Eerd, Magnus Wickman, Torsten Zuberbier, Aziz Sheikh
Google Trends (GT) searches trends of specific queries in Google and reflects the real-life epidemiology of allergic rhinitis. We compared Google Trends terms related to allergy and rhinitis in all European Union countries, Norway and Switzerland from January 1, 2011 to December 20, 2016. The aim was to assess whether the same terms could be used to report the seasonal variations of allergic diseases. Using the Google Trend 5-year graph, an annual and clear seasonality of queries was found in all countries apart from Cyprus, Estonia, Latvia, Lithuania and Malta...
January 31, 2017: Allergy
https://www.readbyqxmd.com/read/28122685/aerobiological-importance-and-allergic-sensitization-to-amaranthaceae-under-arid-climate-conditions
#5
Belén Elvira-Rendueles, Juan J Zapata, Juan C Miralles, José M Moreno, Antonio García-Sánchez, Luis Negral, Stella Moreno-Grau
Species of the Amaranthaceae family are abundant in the Southeast of Spain, one of the driest areas in Europe. The Amaranthaceae include species of interest from the point of view of allergic diseases. With the expansion of aridity, many species belonging to this family will be favoured. The objectives of this study were: first, to define the prevalence of sensitization to Amaranthaceae pollen in allergic patients in the Southeast of Spain; second, to present the aerobiological features of this taxon; and, finally, to demarcate those periods of increased risk of suffering allergic symptoms with the aim of improving the diagnosis and prevention of hay fever...
January 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28103252/comparative-and-evolutionary-analysis-of-grass-pollen-allergens-using-brachypodium-distachyon-as-a-model-system
#6
Akanksha Sharma, Niharika Sharma, Prem Bhalla, Mohan Singh
Comparative genomics have facilitated the mining of biological information from a genome sequence, through the detection of similarities and differences with genomes of closely or more distantly related species. By using such comparative approaches, knowledge can be transferred from the model to non-model organisms and insights can be gained in the structural and evolutionary patterns of specific genes. In the absence of sequenced genomes for allergenic grasses, this study was aimed at understanding the structure, organisation and expression profiles of grass pollen allergens using the genomic data from Brachypodium distachyon as it is phylogenetically related to the allergenic grasses...
2017: PloS One
https://www.readbyqxmd.com/read/28071746/allergy-reduces-the-risk-of-meningioma-a-meta-analysis
#7
Peng-Fei Wang, Wen-Jun Ji, Xiao-Hui Zhang, Shou-Wei Li, Chang-Xiang Yan
Meningiomas are the most common brain tumours; however, little is known regarding their aetiology. The data are inconsistent concerning atopic disease and the risk of developing meningioma. Thus, we conducted a meta-analysis to investigate the association between allergic conditions and the risk of developing meningioma. A systematic literature search was conducted using PubMed and Web of SCI from Jan 1979 to Feb 2016. Two investigators independently selected the relevant articles according to the inclusion criteria...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28017559/spread-of-yellow-fever-virus-outbreak-in-angola-and-the-democratic-republic-of-the-congo-2015-16-a-modelling-study
#8
Moritz U G Kraemer, Nuno R Faria, Robert C Reiner, Nick Golding, Birgit Nikolay, Stephanie Stasse, Michael A Johansson, Henrik Salje, Ousmane Faye, G R William Wint, Matthias Niedrig, Freya M Shearer, Sarah C Hill, Robin N Thompson, Donal Bisanzio, Nuno Taveira, Heinrich H Nax, Bary S R Pradelski, Elaine O Nsoesie, Nicholas R Murphy, Isaac I Bogoch, Kamran Khan, John S Brownstein, Andrew J Tatem, Tulio de Oliveira, David L Smith, Amadou A Sall, Oliver G Pybus, Simon I Hay, Simon Cauchemez
BACKGROUND: Since late 2015, an epidemic of yellow fever has caused more than 7334 suspected cases in Angola and the Democratic Republic of the Congo, including 393 deaths. We sought to understand the spatial spread of this outbreak to optimise the use of the limited available vaccine stock. METHODS: We jointly analysed datasets describing the epidemic of yellow fever, vector suitability, human demography, and mobility in central Africa to understand and predict the spread of yellow fever virus...
December 22, 2016: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28005035/-acute-respiratory-viral-infections-topical-issues-of-diagnosis-prevention-and-treatment-in-therapeutic-practice
#9
D I Trukhan, A L Mazurov, L A Rechapova
AIM: to assess the efficacy and safety of the medication Grippferon with loratadine for the prevention of acute respiratory viral infections (ARVI) and influenza during the epidemics. MATERIAL AND METHODS: This study included 103 patients (67 men and 36 women) aged 18 to 52 years (mean age 35.3±3.2 years). During the first visit (september 2015), we collected patient history data on the average rate of ARVI and influenza for the past three years, the disease duration and its symptoms, presence of concomitant allergic pathologies (such as vasomotor rhinitis, hay fever and urticaria) and food allergies...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27997983/validation-of-international-classification-of-disease-ninth-revision-codes-for-atopic-dermatitis
#10
Derek Y Hsu, Prarthana Dalal, Kimberly A Sable, Nihal Voruganti, Beatrice Nardone, Dennis West, Jonathan I Silverberg
BACKGROUND: Evaluation of large-scale data sets is needed to better understand the epidemiology, cost and burden of atopic dermatitis (AD). We sought to validate the use of ICD-9-CM codes for identifying AD. METHODS: Patients from a large metropolitan quaternary care medical center with a diagnostic code of either 691.8 (AD) or 692.9 (eczema and contact dermatitis) were queried. Medical records were reviewed for demographics, Hanifin & Rajka (H&R) and United Kingdom Working Party (UKWP) criteria...
December 20, 2016: Allergy
https://www.readbyqxmd.com/read/27977844/paracetamol-acetaminophen-or-non-steroidal-anti-inflammatory-drugs-alone-or-combined-for-pain-relief-in-acute-otitis-media-in-children
#11
REVIEW
Alies Sjoukes, Roderick P Venekamp, Alma C van de Pol, Alastair D Hay, Paul Little, Anne Gm Schilder, Roger Amj Damoiseaux
BACKGROUND: Acute otitis media (AOM) is one of the most common childhood infectious diseases and a significant reason for antibiotic prescriptions in children worldwide. Pain from middle ear infection and pressure behind the eardrum is the key symptom of AOM. Ear pain is central to children's and parents' experience of the illness. Because antibiotics provide only marginal benefits, analgesic treatment including paracetamol (acetaminophen) and non-steroidal anti-inflammatory drugs (NSAIDs) is regarded as the cornerstone of AOM management in children...
15, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27941506/relationship-between-birth-weight-or-fetal-growth-rate-and-postnatal-allergy-a-systematic-review-protocol
#12
Amy L Wooldridge, Mark McMillan, Helen S Marshall, Kathryn L Gatford
The objective of this systematic review is to synthesize the best available evidence on the relationship between size at birth or fetal growth and postnatal allergy. Specifically, this review aims to assess evidence regarding relationships between absolute birth weight at term, birth weight corrected for gestational age, expressed as relative to population or customized growth data, or fetal growth measures and physician-diagnosed or parent- and self-reported postnatal clinical allergic disease (eczema/atopic dermatitis, hay fever/rhinitis, allergic asthma or anaphylaxis)...
November 2016: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/27933591/charcoal-hemoperfusion-in-the-treatment-of-medically-refractory-pruritus-in-cholestatic-liver-disease
#13
Wonngarm Kittanamongkolchai, Ziad M El-Zoghby, J Eileen Hay, Russell H Wiesner, Patrick S Kamath, Nicholas F LaRusso, Kymberly D Watt, Carl H Cramer, Nelson Leung
BACKGROUND: Pruritus is a distressing symptom in a considerable proportion of cholestatic patients and a few of them do not respond to conventional treatment. Charcoal hemoperfusion (CH) is an extracorporeal technique that is effective in eliminating protein-bound substances which may have accumulated during cholestasis. Several case reports have shown significant reduction of bilirubin in mechanical jaundice and neonatal hemolytic jaundice. However, the published data of CH for the treatment of refractory pruritus in cholestatic patients are scarce...
December 8, 2016: Hepatology International
https://www.readbyqxmd.com/read/27913581/a-proteomic-approach-to-analyze-the-aspirin-mediated-lysine-acetylome
#14
Michael H Tatham, Christian Cole, Paul Scullion, Ross Wilkie, Nicholas J Westwood, Lesley A Stark, Ronald T Hay
Aspirin, or acetylsalicylic acid is widely used to control pain, inflammation and fever. Important to this function is its ability to irreversibly acetylate cyclooxygenases at active site serines. Aspirin has the potential to acetylate other amino acid side-chains, leading to the possibility that aspirin-mediated lysine acetylation could explain some of its as-yet unexplained drug actions or side-effects. Using isotopically labeled aspirin-d3, in combination with acetylated lysine purification and LC-MS/MS, we identified over 12000 sites of lysine acetylation from cultured human cells...
February 2017: Molecular & Cellular Proteomics: MCP
https://www.readbyqxmd.com/read/27885206/long-term-follow-up-of-a-case-of-apple-allergy-with-systemic-symptoms-through-oral-food-challenges
#15
Tomoyuki Asaumi, Sakura Sato, Noriyuki Yanagida, Mikita Yamamoto, Motohiro Ebisawa
To our knowledge, there are no previous reports of apple allergy with systemic symptoms for which repeated oral food challenges were performed over a long follow-up. The patient was an 8-year-old boy with hay fever. He visited our hospital because of nasal drop, itchy eyes, and dyspnea after lunch every two months for 2 years. Apple allergy was suspected through his medical interview and specific immunoglobulin (Ig) E levels, and he consequently underwent an oral food challenge test. Ninety minutes after ingestion of one whole apple, he experienced coughing, nasal drop, eyelid edema, and conjunctival injection...
2016: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/27856057/mapping-the-birch-and-grass-pollen-seasons-in-the-uk-using-satellite-sensor-time-series
#16
Nabaz R Khwarahm, Jadunandan Dash, C A Skjøth, R M Newnham, B Adams-Groom, K Head, Eric Caulton, Peter M Atkinson
Grass and birch pollen are two major causes of seasonal allergic rhinitis (hay fever) in the UK and parts of Europe affecting around 15-20% of the population. Current prediction of these allergens in the UK is based on (i) measurements of pollen concentrations at a limited number of monitoring stations across the country and (ii) general information about the phenological status of the vegetation. Thus, the current prediction methodology provides information at a coarse spatial resolution only. Most station-based approaches take into account only local observations of flowering, while only a small number of approaches take into account remote observations of land surface phenology...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/27852705/non-treatment-of-children-with-community-health-worker-diagnosed-fast-breathing-pneumonia-in-rural-malawi-exploratory-subanalysis-of-a-prospective-cohort-study
#17
Carina King, Tim Colbourn, Limangeni Mankhambo, James Beard, Debbie C Hay Burgess, Anthony Costello, Rasa Izadnegahdar, Norman Lufesi, Charles Mwansambo, Bejoy Nambiar, Eric S Johnson, Robert W Platt, David Mukanga, Eric D McCollum
BACKGROUND: Despite recent progress, pneumonia remains the largest infectious killer of children globally. This paper describes outcomes of not treating community-diagnosed fast-breathing pneumonia on patient recovery. METHODS: We conducted an exploratory subanalysis of an observational prospective cohort study in Malawi. We recruited children (2-59 months) diagnosed by community health workers with fast-breathing pneumonia using WHO integrated community case management (iCCM) guidelines...
November 16, 2016: BMJ Open
https://www.readbyqxmd.com/read/27819417/clinical-response-to-valproate-in-patients-with-migraine
#18
Mizuki Ichikawa, Hirotaka Katoh, Tatsuya Kurihara, Masakazu Ishii
BACKGROUND AND PURPOSE: Valproate is used as a prophylactic drug for migraine, but it is not be effective in all patients. We used medical records to investigate which clinical factors affected the response to valproate in patients with migraine as an original headache, and established a scoring system for predicting the clinical response to prophylactic therapy. METHODS: We investigated clinical factors from the medical records of 95 consistent responders (CRs) and 24 inconsistent responders (IRs) to valproate...
October 2016: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/27796430/-respiratory-and-allergic-diseases-of-children-temporal-trends-urban-rural-differences-and-in-association-with-environmental-tobacco-smoke-exposure
#19
Kathrin Gürlich, Caroline Herr, Lana Hendrowarsito, Alisa Weber, Uta Nennstiel-Ratzel, Manfred Wildner, Bernhard Liebl, Gabriele Bolte, Rudolf A Jörres, Stefanie Kolb
BACKGROUND/OBJECTIVES: Ten years after the establishment of health monitoring units (GME) in Bavaria, temporal trends and urban-rural differences in parent-reported respiratory and allergic diseases as well as environmental tobacco smoke (ETS) exposure in preschoolers were analyzed in an explorative manner. Furthermore, associations between diseases and ETS exposure were studied. METHODS: Parent questionnaires were used as part of the school entrance examination in two cross sectional studies (S1:2004/2005, n 1 = 6350; S2:2012/2013, n 2 = 5052)...
December 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27793411/evolution-and-predictive-value-of-ige-responses-toward-a-comprehensive-panel-of-house-dust-mite-allergens-during-the-first-2%C3%A2-decades-of-life
#20
Daniela Posa, Serena Perna, Yvonne Resch, Christian Lupinek, Valentina Panetta, Stephanie Hofmaier, Alexander Rohrbach, Laura Hatzler, Linus Grabenhenrich, Olympia Tsilochristou, Kuan-Wei Chen, Carl-Peter Bauer, Ute Hoffman, Johannes Forster, Fred Zepp, Antje Schuster, Ulrich Wahn, Thomas Keil, Susanne Lau, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi
BACKGROUND: The evolution of the IgE response to the numerous allergen molecules of Dermatophagoides pteronyssinus is still unknown. OBJECTIVES: We sought to characterize the evolutionary patterns of the IgE response to 12 molecules of D pteronyssinus from birth to adulthood and to investigate their determinants and clinical relevance. METHODS: We investigated the clinical data and sera of 722 participants in the German Multicenter Allergy Study, a birth cohort started in 1990...
October 19, 2016: Journal of Allergy and Clinical Immunology
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