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https://www.readbyqxmd.com/read/28635547/-healthcare-seems-to-vary-a-lot-a-focus-group-study-among-parents-of-children-with-severe-allergy
#1
Birgitta Lagercrantz, Åsa Persson, Inger Kull
BACKGROUND: Living with an allergic disease has consequences for both affected children and their families. The aim of this qualitative study was to gain deeper knowledge of what life is like for families of children with severe allergic disease, in order to improve care and thereby reduce the consequences of living with a chronic disease. METHODS: Four focus group interviews were performed with Swedish parents of children, aged 6-11 and 12-16 years, with severe allergic disease (from one or more allergic conditions, such as food allergy/eczema/hay fever/asthma)...
February 22, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28628023/-ragweed-allergy-in-the-south-of-russia-in-the-chechen-republic
#2
D Macharadze, H Janaeva, K Avilov
Allergy to ragweed pollen and other weeds is a global problem due to the rapid spread of these grasses around the world. In addition, pollen of short ragweed (Ambrosia, Amb) and mugwort (Artemisia, Art) - one of the main causes of respiratory allergy - seasonal allergic rhinoconjunctivitis (hay fever) with/without bronchial asthma patients living in the South of Russia. Epidemiological studies on the prevalence of Allergy to Amb and Art among patients living in Chechen Republic, absent. Aim - of this retrospective study was to investigate the prevalence of sensitization to weed pollen in patients of Chechnya...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28618023/is-the-atopic-march-related-to-confounding-by-genetics-and-early-life-environment-a-systematic-review-of-sibship-and-twin-data
#3
REVIEW
Sabria J Khan, Shyamali C Dharmage, Melanie C Matheson, Lyle C Gurrin
A popular hypothesis known as the atopic march proposes a set of sequential allergy and respiratory disorders in early childhood contributes enormously to the burden of disease in developed countries. Although the concept of the atopic march has been refined and strengthened by many cross-sectional and longitudinal studies linking eczema as the initial manifestation with progression to hay fever and then asthma, there is yet no definitive proof that the atopic march is the primary causal factor in childhood allergic disease...
June 15, 2017: Allergy
https://www.readbyqxmd.com/read/28589116/gene-environment-interactions-what-can-these-tell-us-about-the-relationship-between-asthma-and-allergy
#4
REVIEW
Steve Turner
Asthma is a common condition, which is associated with atopy and allergic conditions including hay fever, eczema, and food allergies. Asthma and atopy are both complex conditions where genetic and environmental factors are implicated in causation. Interactions between genetic and environmental factors, likely via epigenetic mechanisms, are widely thought to be important in determining the risk for developing asthma and atopy. The nature of the relationship between asthma and atopy is unclear and the answer to the question "does atopy cause asthma?" remains unknown...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28559473/paracetamol-acetaminophen-impairs-brain-masculinisation
#5
Anders Hay-Schmidt, Olivia Finkielman, Benjamin Jensen, Christine Høgsbro, Jacob Bak Holm, Kristoffer Haurum Johansen, Tina Kold Jensen, Anderson Martino Andrade, Shanna Swan, Carl-Gustaf Bornehag, Søren Brunak, Bernard Jegou, Karsten Kristiansen, David Møbjerg Kristensen
Paracetamol/acetaminophen (N-Acetyl-p-Aminophenol; APAP) is the preferred analgesic for pain relief and fever during pregnancy. It has therefore caused concern that several studies have reported that prenatal exposure to APAP results in developmental alterations in both the reproductive tract and the brain. Genitals and nervous system of male mammals are actively masculinized during foetal development and early postnatal life by the combined actions of prostaglandins and androgens, resulting in the male-typical reproductive behaviour seen in adulthood...
May 30, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28555328/evolving-concepts-in-atopic-dermatitis
#6
REVIEW
Robert Sidbury, Kate Khorsand
PURPOSE OF REVIEW: Tremendous advances have been made in the field of atopic dermatitis in the past 5 years. We will explore developments in burden of disease, co-morbidities, pathogenesis, prevention, and management. RECENT FINDINGS: The tremendous burden moderate to severe atopic dermatitis (AD) places on families from a medical, psychosocial, and financial perspective has been characterized. Epidemiologic studies have identified intriguing new associations beyond the well-characterized "atopic march" of food allergies, asthma, and hay fever...
July 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28550983/the-influence-of-asthma-and-or-hay-fever-on-pregnancy-data-from-the-1995-national-survey-of-family-growth
#7
Paul C Turkeltaub, Jooyoung Cheon, Erika Friedmann, Richard F Lockey
BACKGROUND: Asthma is associated with adverse pregnancy outcomes. At the same time there is a worldwide increase in asthma and hay fever. OBJECTIVE: This study addresses whether asthma and/or hay fever adversely influence pregnancy outcomes. METHODS: Data from the 1995 National Survey of Family Growth that include a history of diagnosed asthma, hay fever, and adverse pregnancy outcomes in 10,847 women representative of the US population aged 15 to 44 years were analyzed...
May 24, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28533558/investigating-the-causal-effect-of-smoking-on-hay-fever-and-asthma-a-mendelian-randomization-meta-analysis-in-the-carta-consortium
#8
Tea Skaaby, Amy E Taylor, Rikke K Jacobsen, Lavinia Paternoster, Betina H Thuesen, Tarunveer S Ahluwalia, Sofus C Larsen, Ang Zhou, Andrew Wong, Maiken E Gabrielsen, Johan H Bjørngaard, Claudia Flexeder, Satu Männistö, Rebecca Hardy, Diana Kuh, Sarah J Barry, Line Tang Møllehave, Charlotte Cerqueira, Nele Friedrich, Tobias N Bonten, Raymond Noordam, Dennis O Mook-Kanamori, Christian Taube, Leon E Jessen, Alex McConnachie, Naveed Sattar, Mark N Upton, Charles McSharry, Klaus Bønnelykke, Hans Bisgaard, Holger Schulz, Konstantin Strauch, Thomas Meitinger, Annette Peters, Harald Grallert, Ellen A Nohr, Mika Kivimaki, Meena Kumari, Uwe Völker, Matthias Nauck, Henry Völzke, Chris Power, Elina Hyppönen, Torben Hansen, Torben Jørgensen, Oluf Pedersen, Veikko Salomaa, Niels Grarup, Arnulf Langhammer, Pål R Romundstad, Frank Skorpen, Jaakko Kaprio, Marcus R Munafò, Allan Linneberg
Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic variants as markers of exposures to examine causal effects. We examined the causal effect of smoking on hay fever and asthma by using the smoking-associated single nucleotide polymorphism (SNP) rs16969968/rs1051730. We included 231,020 participants from 22 population-based studies. Observational analyses showed that current vs never smokers had lower risk of hay fever (odds ratio (OR) = 0·68, 95% confidence interval (CI): 0·61, 0·76; P < 0·001) and allergic sensitization (OR = 0·74, 95% CI: 0·64, 0·86; P < 0·001), but similar asthma risk (OR = 1·00, 95% CI: 0·91, 1·09; P = 0·967)...
May 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28498627/a-uk-community-based-survey-on-the-prevalence-of-rhinosinusitis
#9
Amtul S Sami, Glenis K Scadding, Peter Howarth
OBJECTIVES: There is limited information about the prevalence of rhinosinusitis in the UK community. This study aims to identify its prevalence and investigate any association with demographic variables. The secondary aims are to determine the degree of impairment, impact on quality of life and any costs incurred by patients. DESIGN: We used a modified version (MSNOT-20) of a quality of life instrument; the sinonasal outcome test -20 (SNOT-20), in a small and successful pilot project...
May 12, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28482306/mapping-allergenic-pollen-vegetation-in-uk-to-study-environmental-exposure-and-human-health
#10
Rachel N McInnes, Deborah Hemming, Peter Burgess, Donna Lyndsay, Nicholas J Osborne, Carsten Ambelas Skjøth, Sam Thomas, Sotiris Vardoulakis
Allergenic pollen is produced by the flowers of a number of trees, grasses and weeds found throughout the UK. Exposure to such pollen grains can exacerbate pollen-related asthma and allergenic conditions such as allergic rhinitis (hay fever). Maps showing the location of these allergenic taxa have many applications: they can be used to provide advice on risk assessments; combined with health data to inform research on health impacts such as respiratory hospital admissions; combined with weather data to improve pollen forecasting systems; or as inputs to pollen emission models...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28458562/allergic-conditions-are-not-associated-with-the-risk-of-non-hodgkin-s-lymphoma-or-hodgkin-s-lymphoma-a-systematic-review-and-meta-analysis
#11
Jia Yang, Hong'en Xu, Xiaodong Liang, Shiliang Lv, Baihua Lin, Yongshi Jia
We aimed to systematically evaluate the association between allergic conditions and the risk of Hodgkin's lymphoma (HL) and non-HL (NHL). Systematic literature searches in PubMed and Embase were conducted up to October 2015 to identify eligible studies. Either a fixed-effects model or a random-effects model was adopted to estimate overall odds ratios (ORs) according to heterogeneity across studies. Subgroup and publication bias analyses were applied. A total of 24 case-control studies and 13 cohort studies (conducted from 1987 to 2015) were included in the analysis of the risk of NHL...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28411833/atopic-dermatitis-and-comorbidities-added-value-of-comprehensive-dermatoepidemiology
#12
Tamar Nijsten
Atopic dermatitis is common and in its severe form is devastating. This chronic inflammatory dermatosis is part of the atopic syndrome, which includes asthma, food allergies, and hay fever and is known to be associated with mental health disorders. In line with psoriasis, several recent observational studies using national survey and linkage data have suggested a link between atopic dermatitis and cardiovascular disease. The atopic dermatitis field can benefit from the past experiences in psoriasis research and should not follow the same path, but, rather, aim for a more comprehensive approach from the beginning...
May 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28375542/emergence-of-zika-virus-epidemic-and-the-national-response-in-jamaica
#13
K R Webster-Kerr, Cdc Christie, A Grant, D Chin, H Burrowes, K Clarke, I Wellington, K Shaw, W De La Haye
Background: Jamaica, along with the Americas, experienced major epidemics of arboviral diseases transmitted by the Aedes aegypti mosquito in recent years. These include dengue fever in 2012, Chikungunya fever in 2014 and Zika virus infection (ZIKV) in 2016. We present the emergence of the ZIKV epidemic in Jamaica and outline the national response. Methods: The Ministry of Health's preparedness included: heightened surveillance, clinical management guidance, vector control and management, laboratory capacity strengthening, training and staffing, risk communication and public education, social mobilization, inter-sectoral collaboration, resource mobilization and international cooperation...
September 26, 2016: West Indian Medical Journal
https://www.readbyqxmd.com/read/28341882/lifetime-allergic-rhinitis-prevalence-among-us-primary-farm-operators-findings-from-the-2011-farm-and-ranch-safety-survey
#14
Jacek M Mazurek, Paul K Henneberger
PURPOSE: Allergic rhinitis is associated with decreased quality of life, and reduced workplace performance and productivity. This study investigated the prevalence of lifetime allergic rhinitis and factors associated with allergic rhinitis among US primary farm operators. METHODS: The 2011 Farm and Ranch Safety Survey data collected from 11,210 active farm operators were analyzed. Survey respondents were determined to have lifetime allergic rhinitis based on a "yes" response to the question: "Have you ever been told by a doctor, nurse, or other health professional that you had hay fever, seasonal allergies, or allergic rhinitis?" Data were weighted to produce nationally representative estimates...
March 24, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28325597/relationships-between-acrylamide-and-glycidamide-hemoglobin-adduct-levels-and-allergy-related-outcomes-in-general-us-population-nhanes-2005-2006
#15
Jing Guo, Dongdong Yu, Na Lv, Rongpan Bai, Chunjing Xu, Guangdi Chen, Weiming Cao
BACKGROUND: Acrylamide-induced immunotoxicity and allergic dermatitis have been reported in animal experiments and clinical reports, respectively. However, epidemiological evidence from the general population is limited. OBJECTIVES: The purpose of the present study was to estimate the associations between acrylamide exposure and allergy-related outcomes in the general US population. METHODS: A total of 6982 subjects were selected from the National Health and Nutrition Examination Survey 2005-2006 (NHANES)...
March 18, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28315734/comparative-protein-profiles-of-the-ambrosia-plants
#16
Janice S Barton, Rachel Schomacker
Ragweed pollen is primarily responsible for the hay fever allergies of sufferers throughout the world. A proteome study of three ragweed plants (Ambrosia artemisiifolia, Ambrosia trifida, and Ambrosia psilostachya) was undertaken to document and compare their protein profiles. Proteins extracted from the pollen of the three plants were subjected to one dimensional electrophoresis followed by tandem liquid chromatography-mass spectroscopy. Peptide sequence mapping permitted discovery of proteins not previously reported for all three plants and 45% of the identified proteins were shared by all three of them...
June 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28301056/age-at-onset-and-persistence-of-eczema-are-related-to-subsequent-risk-of-asthma-and-hay-fever-from-birth-to-18%C3%A2-years-of-age
#17
Adrian J Lowe, Bianca Angelica, John Su, Caroline J Lodge, David J Hill, Bircan Erbas, Catherine M Bennett, Lyle C Gurrin, Christine Axelrad, Michael J Abramson, Katrina J Allen, Shyamali C Dharmage
BACKGROUND: Few studies have simultaneously addressed the importance of age of onset and persistence of eczema for the subsequent development of asthma and hay fever, particularly into early adulthood. METHODS: A high-risk birth cohort was recruited comprising 620 infants, who were then followed up frequently until 2 years of age, annually from age 3 to 7, then at 12 and 18 years, to document any episodes of eczema, current asthma, and hay fever. The generalized estimation equation technique was used to examine asthma and hay fever outcomes at 6 (n = 325), 12 (n = 248) and 18 (n = 240) years, when there was consistency of associations across the follow-ups...
June 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28199764/clinical-markers-of-asthma-and-ige-assessed-in-parents-before-conception-predict-asthma-and-hayfever-in-the-offspring
#18
R J Bertelsen, M Rava, A E Carsin, S Accordini, B Benediktsdóttir, J Dratva, K A Franklin, J Heinrich, M Holm, C Janson, A Johannessen, D L Jarvis, R Jogi, B Leynaert, D Norback, E R Omenaas, C Raherison, J L Sánchez-Ramos, V Schlünssen, T Sigsgaard, S C Dharmage, C Svanes
BACKGROUND: Mice models suggest epigenetic inheritance induced by parental allergic disease activity. However, we know little of how parental disease activity before conception influences offspring's asthma and allergy in humans. OBJECTIVE: We aimed to assess the associations of parental asthma severity, bronchial hyperresponsiveness (BHR), and total and specific IgEs, measured before conception vs. after birth, with offspring asthma and hayfever. METHODS: The study included 4293 participants (mean age 34, 47% men) from the European Community Respiratory Health Survey (ECRHS) with information on asthma symptom severity, BHR, total and specific IgEs from 1991 to 1993, and data on 9100 offspring born 1972-2012...
May 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28179115/chemical-composition-of-the-essential-oils-and-extracts-of-achillea-species-and-their-biological-activities-a-review
#19
REVIEW
Majid Mohammadhosseini, Satyajit D Sarker, Abolfazl Akbarzadeh
ETHNOPHARMACOLOGICAL RELEVANCE: The Asteraceae (alt. Compositae) family incorporates a large number of flowering plants, which have been classified under ca. 1600 genera covering more than 23,000 species. The genus Achillea is one of the best-known genera of this family. The Achillea species are important for their uses in the chemical and pharmaceutical purposes, and traditional and folk medicines. From ethnobotanical point of view, they heve been recommended as effective tonic, sedative, diuretic and carminative remedies and extensively prescribed for the treatment of stomachache, inflammation, gastrointestinal, hemorrhoid, hay fever, and wound healing in indigenous medicines...
February 5, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28165640/significant-disparities-in-allergy-prevalence-and-microbiota-between-the-young-people-in-finnish-and-russian-karelia
#20
L Ruokolainen, L Paalanen, A Karkman, T Laatikainen, L von Hertzen, T Vlasoff, O Markelova, V Masyuk, P Auvinen, L Paulin, H Alenius, N Fyhrquist, I Hanski, M J Mäkelä, E Zilber, P Jousilahti, E Vartiainen, T Haahtela
BACKGROUND: Atopic allergy has been more common among schoolchildren in Finland, as compared to Russian Karelia. These adjacent regions show one of the most contrasting socio-economical differences in the world. OBJECTIVE: We explored changes in allergy from school age to young adulthood from 2003 to 2010/2012 in these two areas. The skin and nasal microbiota were also compared. METHODS: Randomly selected children from Finnish (n = 98) and Russian Karelia (n = 82) were examined in 2003, when the children were 7-11 years of age, and again in 2010 (Finnish Karelia) and 2012 (Russian Karelia)...
May 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
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