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https://www.readbyqxmd.com/read/29334212/comparison-of-the-efficacy-and-safety-of-palomo-ivanissevich-and-laparoscopic-varicocelectomy-in-iranian-infertile-men-with-palpable-varicocele
#1
Kamal Hosseini, Masoumeh Nejatifar, Ali Kabir
Background: This study aimed to compare the effects of three commonly used varicocelectomy techniques namely, open retroperitoneal ligation (Palomo), open inguinal ligation (Ivanissevich) and laparoscopy, in Iranian infertile men. MATERIALS AND METHODS: This retrospective study was conducted on 70 infertile men with palpable varicocele who underwent one of the varicocelectomy techniques namely, Palomo, Ivanissevich, or laparoscopy. Basic information about semen parameters were collected and registered prior to the surgery...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29334202/lifestyle-related-factors-associated-with-reproductive-health-in-couples-seeking-fertility-treatments-results-of-a-pilot-study
#2
Marie-Lou Piché, Véronique Babineau, Julie Robitaille, Émilie Lachance, Stephanie-May Ruchat
Background: The objective of this pilot study was to evaluate the feasibility of conducting a larger prospective cohort study, which will aim at determining the independent contribution of male and female lifestyle-related factors to assisted reproductive technology (ART) success. The study also examined whether couples seeking fertility treatments present lifestyle-related factors that may interfere with their reproductive health. MATERIALS AND METHODS: This prospective pilot study was conducted in a fertility clinic between May 2015 and February 2016...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29331304/gender-representation-in-urological-subspecialties
#3
Oluwarotimi S Nettey, Joceline S Fuchs, Stephanie J Kielb, Edward M Schaeffer
OBJECTIVE: To examine associations between urologic subspecialization, surgeon gender and practice patterns among certifying urologists over the last 13 years. MATERIALS AND METHODS: Demographic data of certifying and recertifying urologists (2004 to 2015) was obtained from the American Board of Urology (ABU). We investigated gender-specific trends in self-reported practice type (academic practice, private practice), subspecialization, and employment as a full-time versus part-time physician, relative to certification year and cycle...
January 10, 2018: Urology
https://www.readbyqxmd.com/read/29330225/genetics-in-endocrinology-genetic-counseling-for-congenital-hypogonadotropic-hypogonadism-and-kallmann-syndrome-new-challenges-in-the-era-of-oligogenism-and-next-generation-sequencing
#4
Luigi Maione, Andrew A Dwyer, Bruno Francou, Anne Guiochon-Mantel, Nadine Binart, Jerome Bouligand, Jacques Young
Congenital hypogonadotropic hypogonadism (CHH) and Kallmann syndrome (KS) are rare, related diseases that prevent normal pubertal development and cause infertility in affected men and women. However, the infertility carries a good prognosis as increasing numbers of patients with CHH/KS are now able to have children through medically assisted procreation. These are genetic diseases that can be transmitted to patients' offspring. Importantly patients and their families should be informed of this risk and given genetic counseling...
January 12, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29329387/patients-with-acephalic-spermatozoa-syndrome-linked-to-sun5-mutations-have-a-favorable-pregnancy-outcome-from-icsi
#5
Jianzheng Fang, Jingjing Zhang, Fuxi Zhu, Xiaoyu Yang, Yugui Cui, Jiayin Liu
STUDY QUESTION: Are Sad1 and UNC84 domain containing 5 (SUN5) mutations associated with the outcomes of ICSI in patients with acephalic spermatozoa syndrome (ASS)? SUMMARY ANSWER: Despite highly abnormal sperm morphology, ASS patients with SUN5 mutations have a favorable pregnancy outcome following ICSI. WHAT IS KNOWN ALREADY: ASS is a rare cause of infertility characterized by the production of a majority of headless spermatozoa, along with a small proportion of intact spermatozoa with an abnormal head-tail junction...
January 10, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29320903/air-pollution-and-human-sperm-sex-ratio
#6
Michał Radwan, Emila Dziewirska, Paweł Radwan, Lucjusz Jakubowski, Wojciech Hanke, Joanna Jurewicz
The present study was designed to address the hypothesis that exposure to specific air pollutants may impact human sperm Y:X chromosome ratio. The study population consisted of 195 men who were attending an infertility clinic for diagnostic purposes and who had normal semen concentration of 15-300 mln/ml (WHO, 2010). Participants represented a subset of men in a multicenter parent study conducted in Poland to evaluate environmental factors and male fertility. Participants were interviewed and provided a semen sample...
January 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29313203/prevalence-and-antimicrobial-resistance-of-ureaplasma-spp-and-mycoplasma-hominis-isolated-from-semen-samples-of-infertile-men-in-shanghai-china-from-2011-to-2016
#7
Y-H Zhou, H-X Ma, Y Yang, W-M Gu
This study was conducted to estimate the prevalence and antimicrobial resistance rate of Ureaplasma spp. and Mycoplasma hominis that were isolated from the semen samples of infertile males in Shanghai, China from 2011 to 2016. A total of 5016 infertile males and 412 healthy male controls were examined. The cultivation, identification, and antimicrobial susceptibilities of Ureaplasma spp. and M. hominis were assessed by using a Mycoplasma IST kit that was performed in parallel to selective solid agar cultivation...
January 8, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29310165/re-so-much-of-this-story-could-be-me-men-s-use-of-support-in-online-infertility-discussion-boards
#8
Craig Niederberger
No abstract text is available yet for this article.
January 2018: Journal of Urology
https://www.readbyqxmd.com/read/29304248/viable-acrosome-intact-human-spermatozoa-in-the-ejaculate-as-a-marker-of-semen-quality-and-fertility-status
#9
Dorte Louise Egeberg Palme, Anders Rehfeld, Anne Kirstine Bang, Kristiana Alexandrova Nikolova, Søren Kjærulff, Morten Rønn Petersen, Janni Vikkelsø Jeppesen, Martin Glensbjerg, Anders Juul, Niels E Skakkebæk, Søren Ziebe, Niels Jørgensen, Kristian Almstrup
STUDY QUESTION: Is it possible, in an unbiased and clinical relevant way, to determine the number of viable acrosome-intact human spermatozoa in ejaculates and to use this as a measure of fertility chances? SUMMARY ANSWER: Image cytometry enables easy and unbiased quantification of viable acrosome-intact spermatozoa and it correlates with semen quality and fertility status. WHAT IS KNOWN ALREADY: The presence of the acrosome and its ability to respond to physiological inducers (e...
January 2, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29299903/delayed-ejaculation-pathophysiology-diagnosis-and-treatment
#10
REVIEW
Ibrahim A Abdel-Hamid, Omar I Ali
Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase...
January 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29297779/a-partnership-and-coping-enhancement-programme-pcep-for-couples-undergoing-in-vitro-fertilization-treatment-an-intervention-study
#11
Alice Yuen Loke, Liying Ying, Xiangli Wu, Lai Har Wu, Jing Shu
OBJECTIVES: This is a feasibility study to examine the effects of a 'Partnership and Coping Enhancement Programme (PCEP)' on improving the psychological well-being and marital functions of couples undergoing IVF treatment. METHODS: A total of 100 couples were recruited consecutively and assigned to a PCEP intervention group or a routine care control group. The couples in the PCEP group received an additional face-to-face, couple-based, 90-minute session on enhancing partnership and coping on the day of the embryo transfer (ET)...
January 3, 2018: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/29287977/effects-of-herpes-simplex-virus-infections-on-seminal-parameters-in-male-partners-of-infertile-couples
#12
Fábio A Kurscheidt, Edilson Damke, Jaqueline C Bento, Valério A Balani, Karen I Takeda, Sérgio Piva, João P Piva, Mary M T Irie, Fabrícia Gimenes, Marcia E L Consolaro
OBJECTIVE: To assess the possibility that HSV infection could affect seminal parameters we (1) standardize and validate a multiplex polymerase chain reaction (M-PCR) assay to detect HSV-1 and HSV-2 in semen; (2) determine the prevalence of HSV-1/-2 in the semen of randomized male partners of couples seeking fertility evaluation. MATERIALS AND METHODS: A total of 279 semen samples were included in the study from males who visited the Sperm Analysis Section of São Camilo Laboratory of Maringá/Brazil between November 2014 and July 2015...
December 26, 2017: Urology
https://www.readbyqxmd.com/read/29286006/altered-piwi-like-1-and-piwi-like-2-mrna-expression-in-ejaculated-spermatozoa-of-men-with-impaired-sperm-characteristics
#13
Maria Giebler, Thomas Greither, Lisa Müller, Carina Mösinger, Hermann M Behre
In about half the cases of involuntary childlessness, a male infertility factor is involved. The PIWI-LIKE genes, a subclade of the Argonaute protein family, are involved in RNA silencing and transposon control in the germline. Knockout of murine Piwi-like 1 and 2 homologs results in complete infertility in males. The aim of this study was to analyze whether the mRNA expression of human PIWI-LIKE 1-4 genes is altered in ejaculated spermatozoa of men with impaired sperm characteristics. Ninety male participants were included in the study, among which 47 were with normozoospermia, 36 with impaired semen characteristics according to the World Health Organization (WHO) manual, 5th edition, and 7 with azoospermia serving as negative control for the PIWI-LIKE 1-4 mRNA expression in somatic cells in the ejaculate...
December 26, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/29282765/relationships-between-total-testicular-volume-reproductive-parameters-and-surrogate-measures-of-adiposity-in-men-presenting-for-couple-s-infertility
#14
K Ehala-Aleksejev, M Punab
The objective of this study was to investigate the relationships between total testicular volume (TTV), reproductive parameters and adiposity measures: body mass index, waist circumference and waist-to-height ratio. Semen analysis was performed, and reproductive hormone levels were measured in 2,672 male patients (mean age 32.6) due to couple's infertility. Significant, positive correlations between semen parameters and the TTV were found. Gonadotrophins were negatively related to the TTV, and testosterone was not related to the TTV...
December 28, 2017: Andrologia
https://www.readbyqxmd.com/read/29282760/development-and-implementation-of-a-novel-panel-consisting-20-markers-for-the-detection-of-genetic-causes-of-male-infertility
#15
S Bahrami Zadegan, S Dabbagh Bagheri, A Joudaki, M H Samiee Aref, A H Saeidian, M Abiri, S Zeinali
Azoospermia factor (AZF) genes are involved in spermatogenesis. Deletions in the region of these genes have been recognised as a major genetic cause of infertility due to defects in spermatogenesis. Klinefelter syndrome (KS) is the other main cause of male infertility. This study was performed to establish a novel method for the detection of genetic causes of infertility in males and also to investigate the prevalence, extent and position of Y chromosome microdeletions in Iranian infertile men. We developed a newly designed panel of fluorescent multiplex-PCR method to amplify 20 markers (15 sequence-tagged sites (STSs) markers which are placed in the Y chromosome AZF region, 2 short tandem repeats (STRs) and 3 segmental duplications (SDs))...
December 28, 2017: Andrologia
https://www.readbyqxmd.com/read/29282757/level-of-neutral-alpha-1-4-glucosidase-in-seminal-plasma-of-chinese-men
#16
Z Qiu, Q Chu, W Zhang, C Luo, S Quan
Neutral alpha-1,4-glucosidase (NAG) is a crucial biomarker for the function of epididymis and is reported to be associated with semen quality. However, the correlation between NAG and Chinese semen quality has never been reported. This study aimed to investigate the level of NAG in the seminal plasma of Chinese men. A total of 394 cases of seminal plasma samples from normal, subfertile and infertile men were enrolled in this study. Male subfertility was caused by teratozoospermia, asthenospermia, severe oligozoospermia, asthenoteratozoospermia, oligoasthenospermia and oligoasthenoteratozoospermia...
December 28, 2017: Andrologia
https://www.readbyqxmd.com/read/29282417/association-of-blood-and-seminal-plasma-cadmium-and-lead-levels-with-semen-quality-in-non-occupationally-exposed-infertile-men-in-abakaliki-south-east-nigeria
#17
Ademola C Famurewa, Emmanuel I Ugwuja
Objective: To evaluate association of blood and seminal plasma lead and cadmium with sperm quality of non-occupationally exposed male partners of couples with infertility. Materials and methods: A cross-sectional study was conducted on 75 men aged 20-45 years (mean = 37.1 ± 7.0 yrs.) with infertility recruited from the Fertility Clinic of a hospital in Abakaliki. Sperm count done in accordance with the WHO guidelines was used to classify the participants as normospamia, oligospermia and azospermia. Atomic absorption spectrophotometer was used to determine lead and cadmium levels in plasma from blood and semen...
June 2017: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/29280501/-just-because-a-doctor-says-something-doesn-t-mean-that-it-will-happen-self-perception-as-having-a-fertility-problem-among-infertility-patients
#18
Ophra Leyser-Whalen, Arthur L Greil, Julia McQuillan, Katherine M Johnson, Karina M Shrefffler
Only some individuals who have the medically defined condition 'infertility' adopt a self-definition as having a fertility problem, which has implications for social and behavioural responses, yet there is no clear consensus on why some people and not others adopt a medical label. We use interview data from 28 women and men who sought medical infertility treatment to understand variations in self-identification. Results highlight the importance of identity disruption for understanding the dialectical relationship between medical contact and self-identification, as well as how diagnosis acts both as a category and a process...
December 27, 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/29277366/role-of-withania-somnifera-ashwagandha-in-the-management-of-male-infertility
#19
REVIEW
Pallav Sengupta, Ashok Agarwal, Maria Pogrebetskaya, Shubhadeep Roychoudhury, Damayanthi Durairajanayagam, Ralf Henkel
To manage male infertility caused by hormonal imbalance, infections and other predicaments, multifarious treatment strategies are emerging worldwide. Contemporary treatments, such as assisted reproductive techniques, are costly with low success rates of only 10-30%; however, herbal remedies are gaining more attention as an alternative or supplementary therapeutic modality for male infertility. The beneficial effects induced by oral intake of the roots of a small evergreen shrub, Withania sominifera (Ashwagandha) on semen quality of infertile men have previously been studied...
December 7, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29277047/association-of-the-common-snps-in-rnf212-stag3-and-rfx2-gene-with-male-infertility-with-azoospermia-in-chinese-population
#20
Cheng-He Yu, Ting Xie, Ruo-Peng Zhang, Zhou-Cun A
OBJECTIVE: The aim of this study was to explore the association between the SNP rs4045481 in RNF212 gene, rs1050482 and rs11531577 in STAG3 gene as well as rs2288846 in RFX2 gene and male infertility with azoospermia in Chinese population. STUDY DESIGN: Two hundreds and twenty infertile patients with azoospermia and 248 fertile men were recruited in the present study. The four SNPs investigated were genotyped using polymerase chain reaction and restriction fragment length polymorphism assay...
December 15, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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