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Max schmulson

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https://www.readbyqxmd.com/read/27623513/world-gastroenterology-organisation-global-guidelines-irritable-bowel-syndrome-a-global-perspective-update-september-2015
#1
Eamonn M M Quigley, Michael Fried, Kok-Ann Gwee, Igor Khalif, A P S Hungin, Greger Lindberg, Zaigham Abbas, Luis B Fernandez, Shobna J Bhatia, Max Schmulson, Carolina Olano, Anton LeMair
No abstract text is available yet for this article.
October 2016: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/27147123/design-of-treatment-trials-for-functional-gastrointestinal-disorders
#2
E Jan Irvine, Jan Tack, Michael D Crowell, Kok Ann Gwee, Meiyun Ke, Max J Schmulson, William E Whitehead, Brennan Spiegel
This article summarizes recent progress and regulatory guidance on design of trials to assess the efficacy of new therapies for functional gastrointestinal disorders (FGIDs). The double-masked, placebo-controlled, parallel-group design remains the accepted standard for evaluating treatment efficacy. A control group is essential, and a detailed description of the randomization process and concealed allocation method must be included in the study report. The control will most often be placebo, but for therapeutic procedures and for behavioral treatment trials, respectively, a sham procedure and control intervention with similar expectation of benefit, but lacking the treatment principle, are recommended...
May 2016: Gastroenterology
https://www.readbyqxmd.com/read/27144633/rome-iv-design-of-treatment-trials-for-fgids
#3
Brennan Spiegel, Jan E Irvine, Jan Tack, Michael D Crowell, Kok Ann Gwee, Meiyun Ke, Max J Schmulson W
This document summarizes recent progress and regulatory guidance on design of trials to assess efficacy of new therapies for functional gastrointestinal disorders (FGIDs). The double-masked, placebo controlled parallel-group design remains the accepted standard for evaluating treatment efficacy. A control group is essential, and a detailed description of the randomization process and concealed allocation method must be included in the study report. The control will most often be placebo, but for therapeutic procedures and for behavioral treatment trials, respectively a sham procedure and control intervention with similar expectation of benefit but lacking the treatment principle are recommended...
February 18, 2016: Gastroenterology
https://www.readbyqxmd.com/read/27144623/multicultural-aspects-in-functional-gastrointestinal-disorders-fgids
#4
Xiucai Fang, Carlos F Francisconi, Shin Fukudo, Mary-Joan Gerson, Jin-Yong Kang, Max J Schmulson W, Ami D Sperber
Cross-cultural factors are important in functional gastrointestinal disorders (FGIDs). In the setting of FGIDs, the aims of this review were to: 1) engender interest in global aspects; 2) gain a clearer understanding of culture, race and ethnicity and their effect on patient care and research; 3) facilitate cross-cultural clinical and research competency; and 4) improve and foster the quality and conduct of cross-cultural, multinational research. Cultural variables are inevitably present in the physician-patient context...
February 15, 2016: Gastroenterology
https://www.readbyqxmd.com/read/26872819/from-gene-polymorphisms-to-serum-cytokine-levels-in-irritable-bowel-syndrome
#5
Mohammad Bashashati, Max J Schmulson
No abstract text is available yet for this article.
February 9, 2016: Clinics and Research in Hepatology and Gastroenterology
https://www.readbyqxmd.com/read/26818616/the-global-prevalence-of-ibs-in-adults-remains-elusive-due-to-the-heterogeneity-of-studies-a-rome-foundation-working-team-literature-review
#6
Ami D Sperber, Dan Dumitrascu, Shin Fukudo, Charles Gerson, Uday C Ghoshal, Kok Ann Gwee, A Pali S Hungin, Jin-Yong Kang, Chen Minhu, Max Schmulson, Arkady Bolotin, Michael Friger, Tamar Freud, William Whitehead
OBJECTIVES: The global prevalence of IBS is difficult to ascertain, particularly in light of the heterogeneity of published epidemiological studies. The aim was to conduct a literature review, by experts from around the world, of community-based studies on IBS prevalence. DESIGN: Searches were conducted using predetermined search terms and eligibility criteria, including papers in all languages. Pooled prevalence rates were calculated by combining separate population survey prevalence estimates to generate an overall combined meta-prevalence estimate...
January 27, 2016: Gut
https://www.readbyqxmd.com/read/26717934/corrigendum-a-survey-using-the-social-networks-revealed-poor-knowledge-on-fecal-microbiota-transplantation
#7
Patricia Orduña, Sara Y Lopez, Max Schmulson, Rene Arredondo, Samuel Ponce de Leon, Yolanda Lopez-Vidal
This article was initially published on the Journal of Neurogastroenterology and Motility with omission of a funding source. The funding source should be added as the following: "Financial support: This work was supported by DGAPA PAPPIT UNAM (IV200315)."
January 31, 2016: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/25952801/a-review-of-three-educational-projects-using-interactive-theater-to-improve-physician-patient-communication-when-treating-patients-with-irritable-bowel-syndrome
#8
Ben Saypol, Douglas A Drossman, Max J Schmulson, Carolina Olano, Albena Halpert, Ademola Aderoju, Lin Chang
BACKGROUND: Quality communication skills and increased multicultural sensitivity are universal goals, yet teaching them have remained a challenge for educators. OBJECTIVE: To document the process and participant responses to Interactive Theater when used as a method to teach physician/patient communication and cross-cultural competency. DESIGN, SETTING, AND PARTICIPANTS: Three projects are reported. They were collaborations between Theater Delta, the UNC Center for Functional GI and Motility Disorders, the Rome Foundation, the World Gastroenterology Organization, and the American Gastroenterological Association...
May 2015: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/25843083/a-survey-using-the-social-networks-revealed-poor-knowledge-on-fecal-microbiota-transplantation
#9
Patricia Orduna, Sara Y Lopez, Max Schmulson, Rene Arredondo, Samuel Ponce de Leon, Yolanda Lopez-Vidal
No abstract text is available yet for this article.
March 30, 2015: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/25601328/intestinal-microbiota-a-regulator-of-intestinal-inflammation-and-cardiac-ischemia
#10
REVIEW
Mohammad Bashashati, Hamid R Habibi, Ali Keshavarzian, Max Schmulson, Keith A Sharkey
Inflammatory bowel diseases (IBD) are chronic, relapsing and remitting gastrointestinal (GI) disorders of unknown etiology. IBD patients commonly exhibit extra-intestinal manifestations and complications of an inflammatory nature, presenting with disorders such as ankylosing spondylitis, uveitis and vasculitis. Although the metabolic syndrome is less prevalent in patients with IBD, they are at an increased risk for atherosclerosis and cardiovascular events. Considerable evidence supports the role of GI microbiota in the development of IBD...
2015: Current Drug Targets
https://www.readbyqxmd.com/read/24206549/il-10-and-tnf-alpha-polymorphisms-in-subjects-with-irritable-bowel-syndrome-in-mexico
#11
Max Schmulson, Daniela Pulido-London, Óscar Rodríguez, Norma Morales-Rochlin, Rosalinda Martínez-García, María Concepción Gutiérrez-Ruiz, Juan Carlos López-Alvarenga, Gabriela Gutiérrez-Reyes
BACKGROUND: there has been recent evidence of an alteration in irritable bowel syndrome (IBS) immune regulation, as well as variations in cytokine polymorphisms. AIMS: to determine the frequency of the IL-10 (-1082G/A) and TNF-alpha (-308G/A) polymorphisms in subjects with IBS in Mexico. METHODS: volunteers answered the Rome II Questionnaire and were classified as IBS (n = 45) and controls (n = 92). The IBS subjects were then categorized as IBS-D: 22...
August 2013: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/22499071/a-global-perspective-on-irritable-bowel-syndrome-a-consensus-statement-of-the-world-gastroenterology-organisation-summit-task-force-on-irritable-bowel-syndrome
#12
Eamonn M M Quigley, Hussein Abdel-Hamid, Giovanni Barbara, Shobna J Bhatia, Guy Boeckxstaens, Roberto De Giorgio, Michel Delvaux, Douglas A Drossman, Amy E Foxx-Orenstein, Francisco Guarner, Kok-Ann Gwee, Lucinda A Harris, A Pali S Hungin, Richard H Hunt, John E Kellow, Igor L Khalif, Wolfgang Kruis, Greger Lindberg, Carolina Olano, Joaquim P Moraes-Filho, Lawrence R Schiller, Max Schmulson, Magnus Simrén, Christian Tzeuton
Irritable bowel syndrome (IBS) is common in western Europe and North America, and many aspects of its epidemiology, risk factors, and natural history have been described in these regions. Recent data suggest, however, that IBS is also common in the rest of the world and there has been some evidence to suggest some differences in demographics and presenting features between IBS in the west and as it is experienced elsewhere. The World Gastroenterology Organization, therefore, established a Task Force comprising experts on the topic from all parts of the world to examine IBS from a global perspective...
May 2012: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/22474443/the-epidemiology-of-functional-gastrointestinal-disorders-in-mexico-a-population-based-study
#13
Aurelio López-Colombo, Douglas Morgan, Dalia Bravo-González, Alvaro Montiel-Jarquín, Socorro Méndez-Martínez, Max Schmulson
Aims. The frequency of functional gastrointestinal disorders (FGIDs) in the general population of Mexico is unknown. Methods. To determine the prevalence of FGIDs, associated depression, and health care utilization, a population-based sampling strategy was used to select 500 households in the State of Tlaxcala, in central Mexico. Household interviews were conducted by two trained physicians using the Rome II Modular Questionnaire, a health-care and medication used questionnaire and the CES-D depression scale...
2012: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/22474433/irritable-bowel-syndrome-and-gastrointestinal-parasite-infection-in-a-developing-nation-environment
#14
Douglas R Morgan, Matthew Benshoff, Mercedes Cáceres, Sylvia Becker-Dreps, Loreto Cortes, Christopher F Martin, Max Schmulson, Rodolfo Peña
Postinfectious IBS is defined in the industrialized world as IBS onset following a sentinel gastrointestinal infection. In developing nations, where repeated bacterial and parasitic gastrointestinal infections are common, the IBS pathophysiology may be altered. Our aim was to investigate the relationship between intestinal parasite infection and IBS in the "nonsterile" developing world environment. IBS subjects were identified from a population-based sample of 1624 participants using the Rome II Modular Questionnaire...
2012: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/22450013/-receiving-the-baton
#15
EDITORIAL
Max J Schmulson, José María Remes-Troche
No abstract text is available yet for this article.
January 2012: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/22306945/abnormal-immune-regulation-and-low-grade-inflammation-in-ibs-does-one-size-fit-all
#16
EDITORIAL
Max Schmulson, William D Chey
Evidences suggest that there is low-grade inflammation in the colonic mucosa and/or a state of immune activation in patients with irritable bowel syndrome (IBS). Results from available studies are inconsistent mainly because of differences in measures, methodologies and study populations. In this issue, Chang et al. evaluated a comprehensive set of cytokines, immune markers and immune-related cells in patients with non post infectious IBS (non PI-IBS) and controls. The main finding was a lower expression of the mRNA of the anti-inflammatory IL-10 cytokine in the colonic mucosa of women with non PI-IBS without any differences in the cell counts...
February 2012: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/22270083/lower-serum-il-10-is-an-independent-predictor-of-ibs-among-volunteers-in-mexico
#17
Max Schmulson, Daniela Pulido-London, Oscar Rodriguez, Norma Morales-Rochlin, Rosalinda Martinez-García, Ma Concepción Gutierrez-Ruiz, Juan Carlos López-Alvarenga, Guillermo Robles-Díaz, Gabriela Gutiérrez-Reyes
OBJECTIVES: Studies suggest that altered immune activation, manifested by an imbalance in anti- and pro-inflammatory cytokine levels, exists in a subgroup of irritable bowel syndrome (IBS) patients. However, similar studies have not been conducted in Latin populations. The objective of this study was to measure serum levels of interleukin (IL)-10 and tumor necrosis factor (TNF)-α in subjects fulfilling symptom criteria for IBS and controls. METHODS: Volunteers (n=178) from a university population in Mexico City, participated in the study...
May 2012: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/21724488/-guidelines-for-diagnosis-and-treatment-of-constipation-in-mexico-a-epidemiology-meta-analysis-of-the-prevalence-pathophysiology-and-classification
#18
José María Remes Troche, José María Remes Troche, José Luis Tamayo de la Cuesta, Ricardo Raña Garibay, Francisco Huerta Iga, Edgardo Suarez Morán, Max Schmulson
Background: Constipation is a common problem in the general population and its prevalence is based on the diagnostic criteria, the study population and the research methodology for collecting the data. Objectives and Methods: To establish the clinical gudelines for diagnosis and treatment of chronic constipation in Mexico we have reviewed the epidemiological factors of constipation and have conducted meta-analysis according to the 3 available community-based studies from our country. In addition, evidence-based recommendations have been provided...
April 2011: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/21169113/-rome-foundation-diagnostic-algorithms-for-common-gastrointestinal-symptoms-in-spanish
#19
EDITORIAL
Max Schmulson
No abstract text is available yet for this article.
October 2010: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/21103418/from-cytokines-to-toll-like-receptors-and-beyond-current-knowledge-and-future-research-needs-in-irritable-bowel-syndrome
#20
Oscar Rodríguez-Fandiño, Joselín Hernández-Ruiz, Max Schmulson
The irritable bowel syndrome (IBS) is a complex disorder in which psychosocial, cultural and biological factors, interact. Recent knowledge in the pathophysiology of IBS, seem to combine issues such as a low grade inflammation or immune activation and dysbiosis that can trigger or exacerbate IBS. On the other hand, stress mediated through the hypothalamic-pituitary-adrenal axis can produce motility abnormalities that can modify the microbiota as well, with the subsequent immune activation in the mucosa and stimulation of nerve terminals, generating symptoms of IBS...
October 2010: Journal of Neurogastroenterology and Motility
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