Rebecca A Gladdy, Li-Xuan Qin, Nicole Moraco, Mark A Edgar, Cristina R Antonescu, Kaled M Alektiar, Murray F Brennan, Samuel Singer
PURPOSE To determine the prognostic significance of histologic type in radiation-associated soft tissue sarcomas (RASs) and determine whether RASs are associated with an inferior prognosis compared with sporadic soft tissue sarcomas (STSs). PATIENTS AND METHODS One hundred thirty primary RASs were identified from 7,649 STS patients from 1982 to 2007. Multivariate analysis of clinicopathologic factors for disease-specific survival (DSS) was performed for RASs, and a multivariate analysis of radiation exposure was also performed for RASs and sporadic sarcomas...
April 20, 2010: Journal of Clinical Oncology