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https://www.readbyqxmd.com/read/29789878/nuts-as-a-replacement-for-carbohydrates-in-the-diabetic-diet-a-reanalysis-of-a-randomised-controlled-trial
#1
David J A Jenkins, Cyril W C Kendall, Benoît Lamarche, Monica S Banach, Korbua Srichaikul, Edward Vidgen, Sandy Mitchell, Tina Parker, Stephanie Nishi, Balachandran Bashyam, Russell J de Souza, Christopher Ireland, Sathish C Pichika, Joseph Beyene, John L Sievenpiper, Robert G Josse
AIMS/HYPOTHESIS: In line with current advice, we assessed the effect of replacing carbohydrate consumption with mixed nut consumption, as a source of unsaturated fat, on cardiovascular risk factors and HbA1c in type 2 diabetes. The data presented here are from a paper that was retracted at the authors' request ( https://doi.org/10.2337/dc16-rt02 ) owing to lack of adjustment for repeated measures in the same individual. Our aim, therefore, was to fix the error and add new complementary data of interest, including information on clotting factors and LDL particle size...
May 23, 2018: Diabetologia
https://www.readbyqxmd.com/read/29785132/influence-of-fto-rs9939609-polymorphism-on-appetite-ghrelin-leptin-il6-tnf%C3%AE-levels-and-food-intake-of-women-with-morbid-obesity
#2
Fernanda Cristina Carvalho Mattos Magno, Helena Chrispim Guaraná, Ana Carolina Proença Fonseca, Giselda Maria Kalil Cabello, João Régis Ivar Carneiro, Aline Pereira Pedrosa, Ana Carolina Ximenes, Eliane Lopes Rosado
Background: The fat mass and obesity-related ( FTO ) gene has a strong relationship with obesity, extreme obesity and inflammatory state, and may also be associated with food intake regulation. Objective: The aim of the present study was to evaluate the influence of the rs9939609 single-nucleotide polymorphism of the FTO gene on appetite, ghrelin, leptin, interleukin 6 (IL6), tumor necrosis factor α (TNFα) levels and food intake of morbidly obese women. Materials and methods: The study comprised 70 women, aged between 20 and 48 years, from Rio de Janeiro, Brazil...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29770761/low-birth-weight-is-associated-with-increased-fat-intake-in-school-aged-boys
#3
Adrianne R Bischoff, André K Portella, Catherine Paquet, Roberta Dalle Molle, Aida Faber, Narendra Arora, Robert D Levitan, Patrícia P Silveira, Laurette Dube
Evidence suggests that both high and low birth weight children have increased the risk for obesity and the metabolic syndrome in adulthood. Previously we have found altered feeding behaviour and food preferences in pre-school children and adults born with low birth weight. In this study, we investigated if birth weight was associated with different intake of fat, carbohydrate and/or protein at 6-12 years of age. This is a cross-sectional study where 255 guardians answered online and telephone questions including anthropometrics and demographic data, parental family food rules (food control, encouragement and restriction) and a complete web-based FFQ for their children (130 boys and 125 girls)...
June 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29766695/analysis-of-nutrition-and-nutritional-status-of-haemodialysis-patients
#4
Anna Bogacka, Anna Sobczak-Czynsz, Elżbieta Kucharska, Małgorzata Madaj, Katarzyna Stucka
Background: Chronic kidney disease (CKD) is a common disease of civilization where nutrition is part of the treatment. Diet therapy is difficult as it is necessary to control the intake of: energy, protein and minerals – Na, K, Ca and P in the daily food rations (DFR). Objective: The aim of the study was to assess the nutritional status and diets of haemodialysis (HD) patients. Material and method: The study involved 141 haemodialysis patients, at the average age of 65...
2018: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/29752998/effect-of-protein-intake-beyond-habitual-intakes-following-resistance-training-on-cardiometabolic-risk-disease-parameters-in-pre-conditioned-older-women
#5
Rodrigo R Fernandes, Hellen C G Nabuco, Paulo Sugihara Junior, Edilaine F Cavalcanti, Crisieli M Tomeleri, Alex S Ribeiro, Décio S Barbosa, Danielle Venturini, Brad J Schoenfeld, Edilson S Cyrino
OBJECTIVE: The aim of this study was to analyze the effects of higher protein (HP) intake associated with resistance training (RT) on parameters of cardiometabolic risk disease (CMR). METHODS: A randomized, double-blind and placebo-controlled design was conducted. Thirty-two pre-conditioned older women were randomized in two groups to receive 35 g of protein (high protein group - HP) or 35 g of placebo (low protein group - LP) after training sessions. The RT program was carried out over 12 weeks, 3 days per week and 3 sets of 8-12 repetitions...
May 9, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29749015/usual-energy-and-macronutrient-intakes-in-a-large-sample-of-iranian-middle-aged-and-elderly-populations
#6
Zahra Heidari, Awat Feizi, Leila Azadbakht, Noushin Mohammadifard, Maryam Maghroun, Nizal Sarrafzadegan
AIM: The present study aimed to assess the usual distribution of energy and macronutrient intake among a large representative sample of Iranian healthy middle-aged and elderly people. METHODS: In this cross-sectional study, a second follow-up survey of the Isfahan Cohort Study (ICS) was carried out; 1922 people aged 40 years and older were investigated. Dietary intakes were collected using 24-hour recall and two or more consecutive food records. Distribution of energy and macronutrient intake was estimated using traditional and National Cancer Institute (NCI) methods...
May 10, 2018: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29724010/water-soluble-fish-protein-intake-led-to-lower-serum-and-liver-cholesterol-concentrations-in-obese-zucker-fa-fa-rats
#7
Aslaug Drotningsvik, Linn Anja Vikøren, Svein Are Mjøs, Åge Oterhals, Daniela Pampanin, Ola Flesland, Oddrun Anita Gudbrandsen
Proteins from different fish species and different raw materials such as fish fillets and by-products have shown promising cardioprotective effects in rodents and humans, including effects on cholesterol metabolism. Blue whiting is used mainly to produce fish meal for the feed industry and during this production, a water-soluble protein fraction, containing small peptides that are easily absorbed and may hold bioactive properties, is isolated. The effects of water-soluble fish protein on cholesterol metabolism were investigated in twelve male obese Zucker fa/fa rats...
May 1, 2018: Marine Drugs
https://www.readbyqxmd.com/read/29723298/oral-administration-of-short-chain-fatty-acids-could-attenuate-fat-deposition-of-pigs
#8
A R Jiao, H Diao, B Yu, J He, J Yu, P Zheng, Z Q Huang, Y H Luo, J Q Luo, X B Mao, D W Chen
Short chain fatty acids (SCFAs) are the main products of indigestible carbohydrates that are fermented by microbiota in the hindgut. This study was designed to investigate the effects of oral SCFAs administration on the lipid metabolism of weaned pigs. A total of 21 barrows were randomly allocated into three groups, including control group (orally infused with 200 mL physiological saline per day), low dose SCFAs group (orally infused with 200 mL SCFAs containing acetic acid 20.04 mM, propionic acid 7.71 mM and butyric acid 4...
2018: PloS One
https://www.readbyqxmd.com/read/29721804/effects-of-supplementing-barodon-bacillus-subtilis-and-ampbio-on-growth-performance-biochemical-metabolites-and-hormone-levels-in-korean-native-heifers
#9
Tae-Il Kim, Dong-Hyun Lim, Sun-Sik Jang, Sang-Bum Kim, Seong-Min Park, Ji-Hoo Park, Kwang-Seok Ki, Vijayakumar Mayakrishnan
An experiment was conducted to evaluate the effects of supplementing feed additives of Barodon®, effective microorganism® (Bacillus (B.) subtilis), and Ampbio® on the growth performance, blood metabolites, stress, and reproductive hormone levels of Korean native heifers. A total of 48 Korean native heifers were assigned to four groups with 6 heifers in each group. The groups were control, Barodon (0.2%), beneficial microorganism (1%), and Ampbio (1%). Animals in all groups were fed a basal diet composed of selected feed additives and water ad libitum for 99 days...
May 2, 2018: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/29710032/effects-of-chronic-whey-protein-supplementation-on-atherosclerosis-in-apoe-mice
#10
Zheng Zhang, Ru Zhang, Zhi-Zhen Qin, Jia-Ping Chen, Jia-Ying Xu, Li-Qiang Qin
Whey protein is associated with improvement of metabolic syndrome. This study aimed to evaluate effects of whey protein on atherosclerosis in ApoE-/- mice. Male ApoE-/- mice were fed with a high-fat/cholesterol diet (HFCD), or HFCD supplemented with 10% or 20% whey protein for 18 wk. At the end of experiment, serum lipid profiles and inflammatory cytokines were assayed. Livers were examined using HE staining and Oil Red O staining. Aortas were used for en face and cryosection analyses to observe aortic lesions...
2018: Journal of Nutritional Science and Vitaminology
https://www.readbyqxmd.com/read/29705571/association-of-a-cholesteryl-ester-transfer-protein-variant-rs1800777-with-fat-mass-hdl-cholesterol-levels-and-metabolic-syndrome
#11
Daniel de Luis, Olatz Izaola, David Primo, Emilia Gomez, Juan Jose Lopez, Ana Ortola, Rocio Aller
BACKGROUND: There is little evidence of the association between CETP SNPs and obesity and/or related metabolic parameters. OBJECTIVE: To analyze the association of the polymorphism rs1800777 of the CETP gene with anthropometric parameters, lipid profile, metabolic syndrome and its components, and adipokine levels in obese subjects without type 2 diabetes mellitus or hypertension. DESIGN: A population of 1005 obese subjects was analyzed. Electrical bioimpedance was performed, and blood pressure, presence of metabolic syndrome, dietary intake, physical activity, and biochemical tests were recorded...
April 25, 2018: Endocrinología, Diabetes y Nutrición
https://www.readbyqxmd.com/read/29705061/dietary-inflammatory-potential-and-risk-of-mortality-in-metabolically-healthy-and-unhealthy-phenotypes-among-overweight-and-obese-adults
#12
Yong-Moon Mark Park, Moon Kyung Choi, Seong-Su Lee, Nitin Shivappa, Kyungdo Han, Susan E Steck, James R Hébert, Anwar T Merchant, Dale P Sandler
BACKGROUND & AIMS: This study was designed to investigate the association between the dietary inflammatory index (DII® ) scores, metabolic phenotypes, and risk of mortality risk in overweight/obese individuals from a representative sample of the U.S. POPULATION: <AbstractText Label="METHODS" NlmCategory="METHODS">Data from 3733 overweight/obese adults (BMI ≥ 25 kg/m2 ) aged 20-90 years from the National Health and Nutrition Examination Survey III, 1988-1994 were analyzed; these participants were followed for mortality through December 31, 2011...
April 16, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29704554/growth-physiological-antioxidants-and-immune-response-of-african-catfish-clarias-gariepinus-b-to-dietary-clove-basil-ocimum-gratissimum-leaf-extract-and-its-susceptibility-to-listeria-monocytogenes-infection
#13
Mohsen Abdel-Tawwab, Ibrahim Adeshina, Adetola Jenyo-Oni, Emmanual K Ajani, Benjami O Emikpe
Clove basil, Ocimum gratissimum, is a native plant to Africa and grows virtually in tropical and subtropical regions. It has good aroma and its leaves have become used as a spicy and in traditional medicine. The use of plant leaves in fish diets may deteriorate their growth because it may content anti-nutritional factors0 Thus, it is better to use plants leaves extract. In the current study, clove basil leaves extract (CBLE) was administrated to African catfish, Clarias gariepinus (B.) for 12 weeks to evaluate its effect on growth performance, physiological, antioxidants, and innate immunity variables...
April 25, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29681207/effect-of-in-utero-and-lactational-exposure-of-triazophos-on-reproductive-system-functions-in-male-offsprings-rattus-norvegicus
#14
Reetu Bhanot, Gurinder Kaur Sangha
In the present study, Triazophos (TZ) was used at acceptable daily intake (ADI) to investigate the consequence of prenatal and postnatal exposure on reproductive functions in the male offsprings. Pregnant females were divided into three groups, the first group was orally gavaged with olive oil (control), the second group was administered with 0.01 mg kg-1 bw of the ADI of TZ from gestation day (GD) 1 until parturition (designated as P group) and the third group was gavaged with the same dose from GD1 to postnatal day (PND) 21 of lactation (marked as P + L group)...
April 23, 2018: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/29677453/l-carnitine-induced-amelioration-of-hdf-induced-hepatic-dysfunction-is-accompanied-by-a-reduction-in-hepatic-tnf-%C3%AE-and-tgf%C3%AE-1
#15
Mabrouk Attia Abd Eldaim, Fatma Mohamed Ibrahim, Sahar H Orabi, Azza Hassan Morsi, Hesham Saad ElSabbagh
In this study the possible mechanisms through which L-carnitine ameliorates the adverse effects of high fat diet (HFD) induced obesity on rats was evaluated. 56 Wister albino rats were randomly assigned into seven groups. Control rats fed basal diet. 2nd group fed basal diet and injected with L-carnitine 200 mg/kg i.p. 3rd group fed HFD. 4th group fed HFD and injected with L-Carnitine 200 mg/kg i.p for 8 weeks. 5th group fed HFD for 10 weeks. 6th group fed HFD for 10 weeks and injected with L-Carnitine 200 mg/kg i...
April 20, 2018: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29674134/higher-dietary-acid-load-is-associated-with-higher-likelihood-of-peripheral-arterial-disease-among-american-adults
#16
Mohsen Mazidi, Dimitri P Mikhailidis, Maciej Banach
OBJECTIVE: To explore the association between dietary acid load, potential renal acid load (PRAL) and net endogenous acid production (NEAP), and peripheral arterial disease (PAD) in a national representative sample of American adults. METHODS: The National Health and Nutrition Examination Survey (NHANES) database (for 1999-2002) was used. PAD was diagnosed by ankle brachial index assessment. Analysis of covariance was used to examine adjusted mean of different dietary acid load by PAD status; multivariable logistic regression was used to relate dietary acid load with prevalent PAD...
March 9, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29673541/appropriate-protein-intake-is-one-strategy-in-the-management-of-metabolic-syndrome-in-korean-elderly-to-mitigate-changes-in-body-composition
#17
Chorong Oh, Jae-Kyung No
Higher protein intake could reduce metabolic syndrome (MetS) by managing body composition among Korean elderly although the research is scant. Herein, we examined the hypothesis that the optimal protein intake of Korean elderly is associated with both improvements in MetS risk as well as favorable changes in body composition. The present study employs a national data source, the Korea National Health and Nutrition Examination Survey (KNHANES, 2009), and a total 1,567 elderly (651 men and 916 women) were included in the final data analyses...
March 2018: Nutrition Research
https://www.readbyqxmd.com/read/29670663/the-effect-of-sanggua-drink-extract-on-insulin-resistance-through-the-pi3k-akt-signaling-pathway
#18
Yu Cai, Ying Wang, Fei Zhi, Qi-Chang Xing, Yun-Zhong Chen
Treating type 2 diabetes mellitus (T2DM) using thiazolidinediones and biguanides can present several challenges for patients. Sanggua Drink (SGD) is a commonly used agent in traditional Chinese medicine, and it consists of Folium Mori , Fructus Momordicae Charantiae , Radix Puerariae Lobatae , and Rhizoma Dioscorea . The hypoglycemic effects and mechanisms of SGD extracts on insulin resistance in diabetic rats were investigated. SGD (1.24 g/kg orally) was verified in T2DM rats induced by a high-fat diet and streptozotocin...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29668871/transgenic-mice-overexpressing-srebp-1a-in-male-ob-ob-mice-exhibit-lipodystrophy-and-exacerbate-insulin-resistance
#19
Hiroshi Ohno, Takashi Matsuzaka, Nie Tang, Rahul Sharma, Kaori Motomura, Takuya Shimura, Aoi Satoh, Song-Iee Han, Yoshinori Takeuchi, Yuichi Aita, Hitoshi Iwasaki, Shigeru Yatoh, Hiroaki Suzuki, Motohiro Sekiya, Yoshimi Nakagawa, Hirohito Sone, Naoya Yahagi, Nobuhiro Yamada, Yoshikazu Higami, Hitoshi Shimano
Sterol regulatory element-binding protein-1a (SREBP-1a) is a key transcription factor which activates the expression of genes involved in the synthesis of fatty acids, triglycerides, and cholesterol. Transgenic mice that overexpress the nuclear form of SREBP-1a under the control of phosphoenolpyruvate carboxykinase (PEPCK) promoter (Tg-1a) were previously shown to display a lipodystrophic phenotype characterized by enlarged and fatty livers, diminished peripheral white adipose tissue (WAT), and insulin resistance...
April 12, 2018: Endocrinology
https://www.readbyqxmd.com/read/29663407/ground-beef-high-in-total-fat-and-saturated-fatty-acids-decreases-x-receptor-signaling-targets-in-peripheral-blood-mononuclear-cells-of-men-and-women
#20
Seong H Choi, Ghazal Gharahmany, Rosemary L Walzem, Thomas H Meade, Stephen B Smith
We hypothesized that consumption of saturated fatty acids in the form of high-fat ground beef for 5 weeks would depress liver X receptor signaling targets in peripheral blood mononuclear cells (PBMC) and that changes in gene expression would be associated with the corresponding changes in lipoprotein cholesterol (C) concentrations. Older men (n = 5, age 68.0 ± 4.6 years) and postmenopausal women (n = 7, age 60.9 ± 3.1 years) were assigned randomly to consume ground-beef containing 18% total fat (18F) or 25% total fat (25F), five patties per week for 5 weeks with an intervening 4-week washout period...
March 2018: Lipids
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