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Abdominal aortic aneurysm

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https://www.readbyqxmd.com/read/29328848/high-risk-endovascular-aneurysm-repair-a-case-report
#1
Samanthi De Silva
Mr AB is a 66-year old gentleman who presented for elective endovascular aneurysm repair (EVAR) following a routine screening scan identifying a 5.5cm abdominal aortic aneurysm (AAA). He had a past history of chronic obstructive pulmonary disease (COPD) with FEV1/FVC ratio of 48% on pre-assessment. He was hypertensive with a history of ischaemic heart disease (IHD), which has remained asymptomatic following coronary artery bypass grafting (CABG) eight years prior to this presentation.
October 2017: Journal of Perioperative Practice
https://www.readbyqxmd.com/read/29327574/review-on-management-and-outcomes-of-ruptured-abdominal-aortic-aneurysm-in-women
#2
Rita Soares Ferreira, Nelson Gomes Oliveira, José Oliveira-Pinto, Marie J van Rijn, Sander Ten Raa, Hence J Verhagen, Frederico Bastos Gonçalves
Vascular procedures in general, and specifically abdominal aortic aneurysm (AAA) repair, are associated with worse outcomes in female patients. However, how female gender influences outcomes in the setting of aneurysm-rupture remains unclear and may be even more pronounced when compared to elective operations. In this report, the authors aim to review the literature regarding ruptured AAA repair in women. Using the traditional threshold for AAA of 30mm of maximum diameter, the prevalence in women is lesser than in men...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29327568/is-there-an-age-limit-for-abdominal-aortic-aneurysm-repair
#3
Björn Sonesson, Nuno Dias, Tim Resch
INTRODUCTION: There is an increasing number of elderly in society and some of them may have an abdominal aortic aneurysm (AAA). The prevalence of AAA in octo-and non-agenarians indicates that this number could be substantial. The question is; is there an age limit for repair? This complex question incorporates ethical, political, economic and medical aspects. To answer part of this question a review of the outcome of elective and emergent AAA repair in those over 80 was done. EVIDENCE ACQUSITION: A litterature research was done in the Pubmed and Embase databases between 2007 and 2017 for either emergent and/or elective repair of AAA in individuals older than 80 years of age...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29327565/durability-of-fenestrated-endovascular-aortic-repair-for-juxta-renal-abdominal-aortic-aneurysm-repair
#4
Konstantinos Spanos, George Α Antoniou, Athanasios D Giannoukas, Fiona Rohlffs, Nikolaos Tsilimparis, Sebastian E Debus, Tilo Kölbel
BACKGROUND: The aim of this study was to evaluate the long term durability of fenestrated endovascular aortic aneurysm repair (F-EVAR) of juxta-renal aortic aneurysms (JAAAs) in terms of mortality, target visceral vessel (TVV) patency and re-intervention rates. EVIDENCE ACQUISITION: A systematic review and meta-analysis was performed. MEDLINE, CENTRAL, and Cochrane databases were searched with PRISMA methodology for studies reporting on F-EVAR of JAAA presenting follow up > 36 months...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29327561/hostility-of-proximal-aortic-neck-anatomy-in-relation-to-abdominal-aortic-aneurysm-size-and-its-impact-on-the-outcome-of-endovascular-repair-with-the-new-generation-endografts
#5
Christos Karathanos, Konstantinos Spanos, George Kouvelos, Athanasios Athanasoulas, Stylianos Koutsias, Miltiadis Matsagkas, Athanasios D Giannoukas
BACKGROUND: To assess the relation of abdominal aortic aneurysm (AAA) diameter with the proximal neck anatomy (PNA) hostility and to evaluate its impact on the endovascular aneurysm repair (EVAR) outcomes with the use of newer generation endografts. METHODS: Retrospective analysis of single institution's recorded data from February 2009 to April 2016. Patients' characteristics, co-morbidities, aortic morphology, perioperative characteristics and outcomes were analyzed...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29325136/haemodynamic-performance-of-afx-and-nellix-endografts-a-computational-fluid-dynamics-study
#6
Anastasios Raptis, Michalis Xenos, George Kouvelos, Athanasios Giannoukas, Miltiadis Matsagkas
OBJECTIVES: The objective of this study is to analyse the flow conditions in the AFX and Nellix endografts (EGs) accounting for their postimplantation configuration in patients with an endovascular aneurysm repair-treated abdominal aortic aneurysm. METHODS: We reconstructed post-endovascular aneurysm repair computed tomography scans of patients treated with an AFX or Nellix EG creating post-implantation EG models. We examined 16 patients, 8 in each group. The blood flow properties were obtained by computational fluid dynamics simulations and were subsequently compared with physiological infrarenal blood flow properties measured in 5 healthy subjects...
January 8, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29321388/suppression-of-abdominal-aortic-aneurysm-formation-in-mice-by-teneligliptin-a-dipeptidyl-peptidase-4-inhibitor
#7
Yusuke Takahara, Tomotake Tokunou, Toshihiro Ichiki
AIM: Dipeptidyl peptidase-4 (DPP-4) inhibitors lower blood glucose levels through inhibition of incretin degradation, which stimulates insulin secretion. Recent studies reported that DPP-4 inhibitors suppressed atherogenesis in apolipoprotein E-knockout (ApoEKO) mice. In this study, we investigated whether teneligliptin, a DPP-4 inhibitor, affects the development of abdominal aortic aneurysms (AAA) in ApoEKO mice. METHODS: ApoEKO mice were fed a high-fat diet (HFD) and infused with angiotensin (Ang) II by osmotic mini pumps for 4 weeks to induce AAA with (DPP-4i group) or without (control group) teneligliptin administered orally from 1 week before HFD and Ang II infusion to the end of the experiment...
January 10, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/29315369/patency-of-branch-vessels-reimplanted-during-thoraco-abdominal-aortic-replacement-implications-for-the-surgical-technique
#8
Sang Yoon Kim, Suryeun Chung, Dong Jung Kim, Jun Sung Kim, Cheong Lim, Kay-Hyun Park
OBJECTIVES: Reimplantation of branch vessels is an important component of thoraco-abdominal aortic aneurysm repair. The goal of this study was to assess the anatomical results of branch vessel reimplantation, which have rarely been investigated. METHODS: Among 168 patients who underwent computed tomography after thoraco-abdominal aortic aneurysm repair, the technique of branch vessel reimplantation and determination of their patency were investigated. Late computed tomographic images were available for 81 patients (mean interval 55...
January 5, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29313113/epidemiology-and-contemporary-management-of-abdominal-aortic-aneurysms
#9
Brant W Ullery, Richard L Hallett, Dominik Fleischmann
Abdominal aortic aneurysm (AAA) is most commonly defined as a maximal diameter of the abdominal aorta in excess of 3 cm in either anterior-posterior or transverse planes or, alternatively, as a focal dilation ≥ 1.5 times the diameter of the normal adjacent arterial segment. Risk factors for the development of AAA include age > 60, tobacco use, male gender, Caucasian race, and family history of AAA. Aneurysm growth and rupture risk appear to be associated with persistent tobacco use, female gender, and chronic pulmonary disease...
January 9, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29311402/atypical-abdominal-pain-in-a-patient-with-liver-cirrhosis
#10
Liz Toapanta-Yanchapaxi, Eid-Lidt Guering, Ignacio García-Juárez
The causes of abdominal pain in patients with liver cirrhosis and ascites are well-known but occasionally, atypical causes arise. We report the case of a patient with a ruptured, confined abdominal aortic aneurysm.
December 27, 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/29311219/diabetes-reduces-severity-of-aortic-aneurysms-depending-on-the-presence-of-cell-division-autoantigen-1-cda1
#11
Jiaze Li, Pacific Huynh, Aozhi Dai, Tieqiao Wu, Yugang Tu, Bryna Chow, Helen Kiriazis, Xiao-Jun Du, Leon A Bach, Jennifer L Wilkinson-Berka, Erik Biros, Philip Walker, Maria Nataatmadja, Malcolm West, Jonathan Golledge, Terri J Allen, Mark E Cooper, Zhonglin Chai
Diabetes is a negative risk factor for aortic aneurysm, but the underlying explanation for this phenomenon is unknown. We have previously demonstrated that Cell Division Autoantigen 1 (CDA1), which enhances TGF-β signaling, is upregulated in diabetes. We hypothesized that CDA1 plays a key role in conferring the protective effect of diabetes against aortic aneurysms. Male wildtype, CDA1 knockout, Apolipoprotein E (ApoE) knockout and CDA1/ApoE double knockout (dKO) mice were rendered diabetic. Whereas aneurysms were not observed in diabetic ApoE knockout and wildtype mice, 40% of diabetic dKO mice developed aortic aneurysms...
January 8, 2018: Diabetes
https://www.readbyqxmd.com/read/29307934/fistula-between-the-abdominal-aorta-and-a-retroaortic-left-renal-vein-a-rare-complication-of-abdominal-aortic-aneurysm
#12
Leonor Garbin Savarese, Henrique Simão Trad, Edwaldo Edner Joviliano, Valdair Francisco Muglia, Jorge Elias Junior
No abstract text is available yet for this article.
November 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/29307756/the-implications-of-non-compliance-to-endovascular-aneurysm-repair-surveillance-a-systematic-review-and-meta-analysis
#13
REVIEW
Matthew Joe Grima, Mourad Boufi, Martin Law, Dan Jackson, Kate Stenson, Benjamin Patterson, Ian Loftus, Matt Thompson, Alan Karthikesalingam, Peter Holt
OBJECTIVE/BACKGROUND: Increasingly, reports show that compliance rates with endovascular aneurysm repair (EVAR) surveillance are often suboptimal. The aim of this study was to determine the safety implications of non-compliance with surveillance. METHODS: The study was carried out according to the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines. An electronic search was undertaken by two independent authors using Embase, MEDLINE, Cochrane, and Web of Science databases from 1990 to July 2017...
January 4, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29306626/mid-term-outcomes-of-endovascular-repair-of-ruptured-thoraco-abdominal-aortic-aneurysms-with-off-the-shelf-branched-stent-grafts
#14
Kiattisak Hongku, Björn Sonesson, Katarina Björses, Jan Holst, Timothy Resch, Nuno V Dias
OBJECTIVE: To assess the mid-term outcomes and feasibility of branched endovascular repair (b-EVAR) of ruptured thoracoabdominal aortic aneurysms (rTAAAs). METHODS: All patients undergoing b-EVAR of rTAAAs between 2011 and 2016 were included. Pre-, intra and postoperative imaging was reviewed to assess technical success, outcomes, and feasibility of b-EVAR in the emergent setting. RESULTS: Eleven emergency b-EVAR of rTAAAs (10 aneurysms and 1 chronic dissection) were performed using off-the-shelf (OTS) branched stentgrafts...
January 3, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29306602/alpha-2-antiplasmin-arg407lys-polymorphism-and-cryptogenic-ischemic-cerebrovascular-events-association-with-neurological-deficit
#15
Joanna Wzorek, Marek Karpiński, Ewa Wypasek, Michał Michalski, Andrzej Szczudlik, Krzysztof Piotr Malinowski, Anetta Undas
OBJECTIVE: Genetic background of cryptogenic ischemic stroke (IS) and transient ischemic attack (TIA) remains uncertain. Alpha-2-antiplasmin (α2AP) Arg407Lys polymorphism has been shown to be less common in patients with abdominal aortic aneurysm (AAA) compared with healthy controls. We investigated associations of α2AP Arg407Lys polymorphism with cryptogenic IS and TIA. METHODS: We studied 165 consecutive Caucasian patients who experienced cryptogenic IS (n=123) or TIA (n=42)...
December 26, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29301789/consideration-of-sex-differences-in-design-and-reporting-of-experimental-arterial-pathology-studies-statement-from-atvb-council
#16
REVIEW
Peggy Robinet, Dianna M Milewicz, Lisa A Cassis, Nicholas J Leeper, Hong S Lu, Jonathan D Smith
There are many differences in arterial diseases between men and women, including prevalence, clinical manifestations, treatments, and prognosis. The new policy of the National Institutes of Health, which requires the inclusion of sex as a biological variable for preclinical studies, aims to foster new mechanistic insights and to enhance our understanding of sex differences in human diseases. The purpose of this statement is to suggest guidelines for designing and reporting sex as a biological variable in animal models of atherosclerosis, thoracic and abdominal aortic aneurysms, and peripheral arterial disease...
January 4, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29299980/effects-of-atmospheric-pressure-dynamics-on-abdominal-aortic-aneurysm-rupture-onset
#17
Dragan Opacic, Nikola Ilic, Milos Sladojevic, Patrick Schönleitner, Dragan Markovic, Dusan Kostic, Lazar Davidovic
BACKGROUND: The effect of atmospheric pressure (AP) on the onset of abdominal aorta aneurysm rupture (RAAA) remains an unanswered question. We have investigated the seasonal variation and the effect of AP dynamics on RAAA by analysing the largest series of intraoperatively confirmed RAAA. PATIENTS AND METHODS: To realize this study we have performed a retrospective analysis of 546 patients with RAAA, operated within 503 days at the Clinic for vascular and endovascular surgery CCS between 1...
January 4, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29299625/initial-experience-with-the-e-liac%C3%A2-iliac-branch-device-for-the-endovascular-aortic-repair-of-aorto-iliac-aneurysm
#18
Susanne Anton, Marcus Wiedner, Erik Stahlberg, Fabian Jacob, Jörg Barkhausen, Jan Peter Goltz
PURPOSE: Occlusion of internal iliac arteries during endovascular treatment (EVAR) of abdominal aortic (AAA) and common iliac artery aneurysms might be associated with ischemic pelvic complications. This study evaluates technical and clinical success, safety and mid-term results of a novel iliac branch device (IBD) for revascularization of the internal iliac artery (IIA) during EVAR. MATERIALS AND METHODS: Retrospectively, we identified 21 men (mean age 73.3 ± 6...
January 3, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29298371/femorofemoral-crossover-bypass-graft-has-excellent-patency-when-performed-with-evar-for-aaa-with-uiod
#19
Akinfemi A Akingboye, Bijendra Patel, Frank W Cross
OBJECTIVES: To compare the durability of the crossover femorofemoral bypass graft (CFFBG) in combination with aorto-uni-iliac stent graft (AUIS) for abdominal aortic aneurysm with the durability of CFFBG used in the treatment of unilateral iliac occlusive disease (UIOD). METHODS: We analyzed the clinical records of 69 patients who underwent CFFBG from 1992 until 2010. Group I consisted of 34 patients who received CFFBGs in combination with AUIS. Group II consisted of 35 patients treated with CFFBG for UIOD...
January 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29296021/homocysteine-directly-interacts-and-activates-the-angiotensin-ii-type-i-receptor-to-aggravate-vascular-injury
#20
Tuoyi Li, Bing Yu, Zhixin Liu, Jingyuan Li, Mingliang Ma, Yingbao Wang, Mingjiang Zhu, Huiyong Yin, Xiaofeng Wang, Yi Fu, Fang Yu, Xian Wang, Xiaohong Fang, Jinpeng Sun, Wei Kong
Hyperhomocysteinemia (HHcy) is a risk factor for various cardiovascular diseases. However, the mechanism underlying HHcy-aggravated vascular injury remains unclear. Here we show that the aggravation of abdominal aortic aneurysm by HHcy is abolished in mice with genetic deletion of the angiotensin II type 1 (AT1) receptor and in mice treated with an AT1 blocker. We find that homocysteine directly activates AT1 receptor signalling. Homocysteine displaces angiotensin II and limits its binding to AT1 receptor. Bioluminescence resonance energy transfer analysis reveals distinct conformational changes of AT1 receptor upon binding to angiotensin II and homocysteine...
January 2, 2018: Nature Communications
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