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Abdominal aortic aneurysm

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https://www.readbyqxmd.com/read/28746184/theoretical-mechanism-of-temporary-renal-function-improvement-after-abdominal-aortic-aneurysm-surgery-applications-for-clinical-imaging-and-laboratory-data
#1
Katsuyuki Hoshina, Takafumi Akai, Marie Ohshima, Toshiaki Watanabe, Sota Yamamoto
We evaluated the effects of changes in blood flow due to abdominal aortic aneurysm (AAA) surgery by using a simple zero-dimension model and applied theoretical values to clinical data.The zero-dimension electronic circuit model and diagram of blood flow distribution were created by setting the resistance of the aorta, bilateral iliac arteries, renal arteries, and aneurysm. Resistance of the aneurysm and resistance of the aorta before surgery were compared with that of the aorta after surgery. We set the radius length of each anatomical parameter to calculate theoretical values...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28746156/textbook-outcome-a-composite-measure-for-quality-of-elective-aneurysm-surgery
#2
Eleonora G Karthaus, Niki Lijftogt, Linde A D Busweiler, Bernard H P Elsman, Michel W J M Wouters, Anco C Vahl, Jaap F Hamming
OBJECTIVE: To investigate a new composite quality measurement, which comprises a desirable outcome for elective aneurysm surgery, called "Textbook Outcome" (TO). BACKGROUND: Single-quality indicators in vascular surgery are often not distinctive and insufficiently reflect the quality of care. METHODS: All patients undergoing elective abdominal aortic aneurysm repair, registered in the Dutch Surgical Aneurysm Audit between 2014 and 2015 were included...
July 25, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28745787/short-term-and-long-term-effects-of-covered-stent-endovascular-graft-exclusion-for-the-treatment-of-abdominal-aortic-aneurysm-rupture
#3
L Li, Y-Q Li, B Liu, H Wang, D-M Zhang
OBJECTIVE: We studied short-term and long-term effects of covered stent endovascular graft exclusion for the treatment of abdominal aortic aneurysm rupture. PATIENTS AND METHODS: From January 2013 to January 2016, 88 patients with fractured abdominal aortic aneurysm were enrolled in this study. Patients were divided into the control group or the open abdomen group (n=52) and the observation group or the isolated group (n=36). Patients in the control group were treated with open abdominal aneurysm resection and artificial blood vessel transplant technique, while patients in the observation group were treated with percutaneous stent graft endovascular graft exclusion...
July 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28745403/sex-differences-in-mortality-after-abdominal-aortic-aneurysm-repair-in-the-uk
#4
D A Sidloff, A Saratzis, M J Sweeting, J Michaels, J T Powell, S G Thompson, M J Bown
BACKGROUND: The UK abdominal aortic aneurysm (AAA) screening programmes currently invite only men for screening because the benefit in women is uncertain. Perioperative risk is critical in determining the effectiveness of screening, and contemporary estimates of these risks in women are lacking. The aim of this study was to compare mortality following AAA repair between women and men in the UK. METHODS: Anonymized data from the UK National Vascular Registry (NVR) for patients undergoing AAA repair (January 2010 to December 2014) were analysed...
July 26, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28743822/bronchial-microdialysis-monitoring-of-inflammatory-response-in-open-abdominal-aortic-aneurysm-repair-an-observational-study
#5
Stig S Tyvold, Torbjørn Dahl, Stein Dragsund, Sigurd Gunnes, Oddveig Lyng, Jan K Damås, Petter Aadahl, Erik Solligård
Aortic surgery results in ischemia-reperfusion injury that induces an inflammatory response and frequent complications. The magnitude of the inflammatory response in blood and bronchi may be associated with the risk of immediate complications. The purpose of the study was to evaluate bronchial microdialysis as a continuous monitoring of cytokines in bronchial epithelial lining fluid (ELF) and to determine whether bronchial ELF cytokine levels reflect the ischemia-reperfusion injury and risk for complications during open abdominal aortic aneurysm (AAA) repair...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28743219/use-of-a-thoracic-endograft-in-an-acute-abdominal-aortic-setting-case-report-and-literature-review
#6
Sebastiano Tasselli, Paolo Perini, Elisa Paini, Luca Milan, Stefano Bonvini
PURPOSE: We report the case of a thoracic endograft used to achieve exclusion of a ruptured proximal paranastomotic abdominal aortic aneurysm (PAAA) as a consequence of aortic ballooning. CASE REPORT: A type I proximal endoleak was evidenced following endovascular repair of a PAAA with an aortic cuff. The leak was treated with ballooning, which caused distal aortic rupture. A thoracic endograft was deployed inside the cuff, achieving complete exclusion. At 1 year, there are no signs of migration or endoleak with complete PAAA thrombosis, according to computed tomographic angiography...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28742684/endovascular-repair-of-abdominal-aortic-aneurysm-in-patients-physically-ineligible-for-open-repair-very-long-term-follow-up-in-the-evar-2-randomized-controlled-trial
#7
Michael J Sweeting, Rajesh Patel, Janet T Powell, Roger M Greenhalgh
OBJECTIVE: The aim of the study was to compare long-term total and aneurysm-related mortality in physically frail patients with abdominal aortic aneurysm (AAA) randomized to either early endovascular aneurysm repair (EVAR) or no-intervention. SUMMARY BACKGROUND DATA: EVAR-2 remains the sole randomized trial to identify whether EVAR reduces mortality in patients physically ineligible for open repair. METHODS: Between September 1999 and August 2004, 404 patients from 33 centers in the United Kingdom aged ≥60 years with AAA >5...
July 24, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28741676/the-association-of-abdominal-muscle-with-outcomes-after-scheduled-abdominal-aortic-aneurysm-repair
#8
N Shah, L Abeysundara, P Dutta, M Christodoulidou, S Wylie, T Richards, N Schofield
Sarcopenia is the degenerative loss of core muscle mass. It is an aspect of frailty, which is associated with increased rates of peri-operative harm. We assessed the association of the cross-sectional areas of abdominal muscles, including psoas, with survival during a median (IQR [range]) follow-up of 3.8 (3.2-4.4 [0.0-5.1]) years after scheduled endovascular (132) or open (5) abdominal aortic aneurysm repair in 137 patients. In multivariate analysis, mortality hazard (95%CI) was independently associated with: age, 1...
July 25, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28741441/atmospheric-pressure-and-abdominal-aortic-aneurysm-rupture-results-from-a-time-series-analysis-and-case-crossover-study
#9
Bas B L Penning de Vries, Joé L P Kolkert, Robbert Meerwaldt, Rolf H H Groenwold
BACKGROUND: Associations between atmospheric pressure and abdominal aortic aneurysm (AAA) rupture risk have been reported, but empirical evidence is inconclusive and largely derived from studies that did not account for possible nonlinearity, seasonality, and confounding by temperature. METHODS: Associations between atmospheric pressure and AAA rupture risk were investigated using local meteorological data and a case series of 358 patients admitted to hospital for ruptured AAA during the study period, January 2002 to December 2012...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28740836/mycotic-aneurysm-with-aortoduodenal-fistula
#10
REVIEW
Bruno Kusznir Vitturi, Amanda Frias, Raphael Sementilli, Marcelo de Castro Jorge Racy, Roberto Augusto Caffaro, Geanete Pozzan
Firstly described in the 19th century by Sir William Osler, the mycotic aneurysm (MA) is a rare entity characterized by an abnormal arterial dilation, which is potentially fatal, and is associated with the infection of the vascular wall. Elderly patients are mostly involved, especially when risk factors like chronic diseases, immunosuppression, neoplasia, and arterial manipulation are associated. The authors report the case of a young male patient diagnosed with an aortic aneurysm of infectious origin in the presence of repeated negative blood cultures...
April 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28739467/epidemiology-and-outcomes-of-abdominal-aortic-aneurysms-in-new-zealand-a-15-year-experience-at-a-regional-hospital
#11
Nathaniel Chiang, Jitendra K Jain, Katherine R Hulme, Thodur Vasudevan
INTRODUCTION: Abdominal aortic aneurysms (AAA) account for approximately 400 deaths per year in New Zealand (NZ). Waikato Hospital caters to a diverse population comprising a high proportion of the indigenous Māori ethnic group considered to be at higher risk of mortality and morbidity. Despite these population factors, there is no screening program for AAA. The aim of this study was to further define the epidemiology and outcomes of AAA repairs in NZ to investigate the utility of implementing a population-specific screening program...
July 21, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28739458/effects-of-chemotherapy-in-patients-with-concomitant-aortic-aneurysm-and-malignant-disease
#12
Marco Leopardi, Evelina Di Marco, Aldo Musilli, Enrico Ricevuto, Gemma Bruera, Marco Ventura
BACKGROUND: The aim of the study is to present the results in a consecutive series of patients affected by aortic abdominal aneurysm and to underline the aneurysmal growth and evolution in oncological patients submitted to dedicated oncological medical therapy. METHODS: Between January 2010 and June 2016 we treated in our center 19 patients for coexisting aortic aneurysms (>3cm) and malignancy. We observed patients undergoing oncological treatment and patients who did not undergo medical treatment...
July 21, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28737060/a-propensity-score-matched-analysis-of-inflammatory-response-with-endovascular-aneurysm-sealing-vs-endovascular-aneurysm-repair
#13
Patrick Berg, Roland A Stroetges, Larry E Miller, Jochen Schoefferle
PURPOSE: To evaluate the risk of postimplantation syndrome associated with endovascular aneurysm sealing (EVAS) and endovascular aneurysm repair (EVAR) in patients treated for abdominal aortic aneurysm (AAA). METHODS: From December 2013 to May 2015, 41 AAA patients treated with EVAS (mean age 72±9 years; 38 men) and 63 with EVAR (mean age 74±10 years; 55 men) at a single center were retrospectively reviewed. To control for treatment selection bias, propensity score matching was used to compare outcomes by treatment mode...
July 1, 2017: Journal of Endovascular Therapy
https://www.readbyqxmd.com/read/28736120/aneurysmal-degeneration-of-type-b-aortic-dissections-after-thoracic-endovascular-aortic-repair-a-systematic-review
#14
REVIEW
Marissa Famularo, Karol Meyermann, Joseph V Lombardi
BACKGROUND: Promising results of thoracic endovascular aortic repair (TEVAR) in patients with complicated type B aortic dissection (TBAD) have been well documented. However, whereas early results have led many to hypothesize a benefit of TEVAR in uncomplicated patients, the natural history of TEVAR after the treatment of TBAD has yet to mature. In this review, we evaluated the available data to investigate whether longer term TEVAR warrants enthusiasm for all comers with TBAD. METHODS: A systematic review of the literature was performed searching specifically for studies assessing medium- and long-term outcomes after TEVAR for the treatment of TBAD...
July 20, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28735510/fxa-inhibition-by-rivaroxaban-modifies-mechanisms-associated-with-the-pathogenesis-of-human-abdominal-aortic-aneurysms
#15
G Moñux, J J Zamorano-León, P Marqués, B Sopeña, J M García-García, G Laich de Koller, B Calvo-Rico, M A García-Fernandez, J Serrano, A López-Farré
AIM: To evaluate if Rivaroxaban, an oral factor Xa (FXa) inhibitor, could in vitro modify the expression of inflammatory and oxidative stress biomarkers in abdominal aortic aneurysmal (AAA) sites showing intraluminal thrombus. METHODS: AAA sites with intraluminal mural thrombus were obtained from six patients undergoing elective AAA repair. In addition, control abdominal aortic samples were obtained from six organ donors. AAA sites were incubated in the presence and absence of 50 nmol/L Rivaroxaban...
July 23, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28735253/how-should-i-treat-a-patient-with-a-symptomatic-and-severe-low-flow-low-gradient-aortic-stenosis-and-an-incidental-abdominal-aortic-aneurysm
#16
Zouhair Rahhab, Sander Ten Raa, Nathalie van der Ploeg, Nicolas M Van Mieghem, Hence Verhagen, Peter P T de Jaegere, Mani Arsalan, Won Kim, Thomas Walther, Didier Tchétché
No abstract text is available yet for this article.
July 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28734943/deficits-in-col5a2-expression-result-in-novel-skin-and-adipose-abnormalities-and-predisposition-to-aortic-aneurysms-and-dissections
#17
Arick C Park, Noel Phan, Dawiyat Massoudi, Zhenjie Liu, John F Kernien, Sheila M Adams, Jeffrey M Davidson, David E Birk, Bo Liu, Daniel S Greenspan
Classic Ehlers-Danlos syndrome (cEDS) is characterized by fragile, hyperextensible skin and hypermobile joints. cEDS can be caused by heterozygosity for missense mutations in genes COL5A2 and COL5A1, which encode the α2(V) and α1(V) chains, respectively, of collagen V, and is most often caused by COL5A1 null alleles. However, COL5A2 null alleles have yet to be associated with cEDS or other human pathologies. We previously showed that mice homozygous null for the α2(V) gene Col5a2 are early embryonic lethal, whereas haploinsufficiency caused aberrancies of adult skin, but not a frank cEDS-like phenotype, as skin hyperextensibility at low strain and dermal "cauliflower"-contoured collagen fibril aggregates, two cEDS hallmarks, were absent...
July 19, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28729364/tgf-%C3%AE-transforming-growth-factor-%C3%AE-signaling-protects-the-thoracic-and-abdominal-aorta-from-angiotensin-ii-induced-pathology-by-distinct-mechanisms
#18
Stoyan N Angelov, Jie Hong Hu, Hao Wei, Nathan Airhart, Minghui Shi, David A Dichek
OBJECTIVE: The role of TGF-β (transforming growth factor-β) signaling in abdominal aortic aneurysm (AAA) formation is controversial. Others reported that systemic blockade of TGF-β by neutralizing antibodies accelerated AAA development in angiotensin II-infused mice. This result is consistent with other studies suggesting that TGF-β signaling prevents AAA. Development of a therapy for AAA that exploits the protective actions of TGF-β would be facilitated by identification of the mechanisms through which TGF-β prevents AAA...
July 20, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28728780/detecting-regional-stiffness-changes-in-aortic-aneurysmal-geometries-using-pressure-normalized-strain
#19
Doran S Mix, Ling Yang, Camille C Johnson, Nathan Couper, Ben Zarras, Isaac Arabadjis, Lauren E Trakimas, Michael C Stoner, Steven W Day, Michael S Richards
Transabdominal ultrasound elasticity imaging could improve the assessment of rupture risk for abdominal aortic aneurysms by providing information on the mechanical properties and stress or strain states of vessel walls. We implemented a non-rigid image registration method to visualize the pressure-normalized strain within vascular tissues and adapted it to measure total strain over an entire cardiac cycle. We validated the algorithm's performance with both simulated ultrasound images with known principal strains and anatomically accurate heterogeneous polyvinyl alcohol cryogel vessel phantoms...
July 17, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28727673/exercise-training-improves-ventilatory-efficiency-in-patients-with-a-small-abdominal-aortic-aneurysm-a-randomized-controlled-study
#20
Ricardo M Lima, Baruch Vainshelboim, Rucha Ganatra, Ronald Dalman, Khin Chan, Jonathan Myers
PURPOSE: To investigate the effects of exercise training on ventilatory efficiency and physiological responses to submaximal exercise in subjects with small abdominal aortic aneurysm (AAA). METHODS: Sixty-five male patients (72.3 ± 7.0 years) were randomized to exercise training (n = 33) or usual care group (n = 32). Exercise subjects participated in a training groups for 3 mo. Cardiopulmonary exercise testing was performed before and after the study period and peak VO2, the ventilatory threshold (VT), the oxygen uptake efficiency slope (OUES), and the VE2/VCO2 slope were identified...
July 19, 2017: Journal of Cardiopulmonary Rehabilitation and Prevention
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