keyword
MENU ▼
Read by QxMD icon Read
search

Terpenoid

keyword
https://www.readbyqxmd.com/read/28633414/an-extended-model-of-heartwood-secondary-metabolism-informed-by-functional-genomics
#1
Jose M Celedon, Jörg Bohlmann
The development of heartwood (HW) and the associated accumulation of secondary metabolites, which are also known as 'specialized metabolites' or 'extractives', is an important feature of tree biology. Heartwood development can affect tree health with broader implications for forest health. Heartwood development also defines a variety of wood quality traits that are important in the forest industry such as durability and colour of wood products. In the bioproducts industry, HW provides a source of high-value small molecules such as fragrances and antimicrobials...
June 14, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28629407/antibacterial-activity-of-crude-extracts-of-some-south-african-medicinal-plants-against-multidrug-resistant-etiological-agents-of-diarrhoea
#2
Mary A Bisi-Johnson, Chikwelu L Obi, Babatunde B Samuel, Jacobus N Eloff, Anthony I Okoh
BACKGROUND: This study evaluated the antibacterial activity of some plants used in folklore medicine to treat diarrhoea in the Eastern Cape Province, South Africa. METHODS: The acetone extracts of Acacia mearnsii De Wild., Aloe arborescens Mill., A. striata Haw., Cyathula uncinulata (Schrad.) Schinz, Eucomis autumnalis (Mill.) Chitt., E. comosa (Houtt.) Wehrh., Hermbstaedtia odorata (Burch. ex Moq.) T.Cooke, Hydnora africana Thunb, Hypoxis latifolia Wight, Pelargonium sidoides DC, Psidium guajava L and Schizocarphus nervosus (Burch...
June 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28629223/essential-oil-composition-of-erica-spiculifolia-salisb-first-report
#3
Violeta D Mitic, Marija D Ilic, Vesna P Stankov-Jovanovic, Gordana S Stojanovic, Marija V Dimitrijevic
The essential oil isolated from Erica spiculifolia Salisb. by hydrodistillation was analysed by GC-MS. One hundred compounds representing 92.6% of total oil were identified. Among the detected compounds 38 were monoterpenoids (46.2%), 30 were sesquiterpenoids (31.7%), 2 diterpene (0.4%) and 30 compounds (14.3%) were with various non-terpenoid structures. Oxygenated monoerpenes were by far the main class (45.3%) with α-terpineol (7.5%) endo-borneol (7.2%), pinocarveol (5.9%) and thymol (3.7%) as the major compounds...
June 19, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28629120/metabolomics-characterization-of-two-apocynaceae-plants-catharanthus-roseus-and-vinca-minor-using-gc-ms-and-lc-ms-methods-in-combination
#4
Qi Chen, Xueyan Lu, Xiaorui Guo, Qingxi Guo, Dewen Li
Catharanthus roseus (C. roseus) and Vinca minor (V. minor) are two common important medical plants belonging to the family Apocynaceae. In this study, we used non-targeted GC-MS and targeted LC-MS metabolomics to dissect the metabolic profile of two plants with comparable phenotypic and metabolic differences. A total of 58 significantly different metabolites were present in different quantities according to PCA and PLS-DA score plots of the GC-MS analysis. The 58 identified compounds comprised 16 sugars, eight amino acids, nine alcohols and 18 organic acids...
June 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28629116/systematic-review-of-chemical-constituents-in-the-genus-lycium-solanaceae
#5
REVIEW
Dan Qian, Yaxing Zhao, Guang Yang, Luqi Huang
The Lycium genus is widely used as a traditional Chinese medicine and functional food. Many of the chemical constituents of the genus Lycium were reported previously. In this review, in addition to the polysaccharides, we have enumerated 355 chemical constituents and nutrients, including 22 glycerogalactolipids, 29 phenylpropanoids, 10 coumarins, 13 lignans, 32 flavonoids, 37 amides, 72 alkaloids, four anthraquinones, 32 organic acids, 39 terpenoids, 57 sterols, steroids, and their derivatives, five peptides and three other constituents...
June 8, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28627245/phytochemical-screening-and-in-vitro-evaluation-of-pharmacological-activities-of-peels-of-musa-sapientum-and-carica-papaya-fruit
#6
Sarmad Siddique, Shamsa Nawaz, Faqir Muhammad, Bushra Akhtar, Bilal Aslam
Aqueous, absolute and 80% ethanolic extract of fruit peels of Musa sapientum and Carica papaya were investigated for their antibacterial activity, measured by disc diffusion method and antioxidant activity, measured by four different methods. Papaya and banana peels were found to contain terpenoids, tannins, alkaloids, saponins steroid, phenols, fixed oils and fats. 80% ethanolic extract of banana peel was found to contain highest total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity but in papaya peel, highest TPC and reducing activity was shown by water extract while, TFC and radical scavenging activity was given by 80% ethanolic extract...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28627075/chemistry-of-two-distinct-aeolid-spurilla-species-ecological-implications
#7
M Letizia Ciavatta, Stella García-Matucheski, Marianna Carbone, Guido Villani, Claudia Muniain, Margherita Gavagnin
The lipophilic extracts of two marine aeolid nudibranch molluscs of the genus Spurilla collected in distinct geographical areas have been chemically analysed. The Et2 O extracts of the nudibranchs were dominated by the presence of usual fatty acids and sterols and contained terpenoid compounds 1-3 as minor metabolites. Spurillin A (1) and spurillin B (3) were new molecules whereas cis-γ-monocyclo-farnesol (2) was already reported in the literature as a synthesis product. Interestingly, bursatellin (4), previously isolated from anaspidean molluscs of the genus Bursatella, was found in the butanol extract of both Spurilla species...
June 19, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28625730/terpenoids-from-curcuma-wenyujin-increased-glucose-consumption-on-hepg2-cells
#8
Chang-Xin Zhou, Li-Sha Zhang, Fei-Fei Chen, Hao-Shu Wu, Jian-Xia Mo, Li-She Gan
Thirty four terpenoids, including two new cadinane-type sesquiterpenoids containing conjugated aromatic-ketone moieties, curcujinone A (1) and curcujinone B (2), were isolated from 95% ethanol extract of the root tubers of Curcuma wenyujin. Their structures were determined by spectroscopic methods, especially 2D NMR and HRMS techniques. The relative and absolute configurations of 1 and 2 were identified by quantum chemical DFT and TDDFT calculations of the (13)C NMR chemical shifts, ECD spectra, and specific optical rotations...
June 15, 2017: Fitoterapia
https://www.readbyqxmd.com/read/28623722/recent-advances-in-synthetic-biology-for-engineering-isoprenoid-production-in-yeast
#9
REVIEW
Claudia E Vickers, Thomas C Williams, Bingyin Peng, Joel Cherry
Isoprenoids (terpenes/terpenoids) have many useful industrial applications, but are often not produced at industrially viable level in their natural sources. Synthetic biology approaches have been used extensively to reconstruct metabolic pathways in tractable microbial hosts such as yeast and re-engineer pathways and networks to increase yields. Here we review recent advances in this field, focusing on central carbon metabolism engineering to increase precursor supply, re-directing carbon flux for production of C10, C15, or C20 isoprenoids, and chemical decoration of high value diterpenoids (C20)...
June 14, 2017: Current Opinion in Chemical Biology
https://www.readbyqxmd.com/read/28618209/chemical-compositions-antioxidant-and-antimicrobial-activities-of-essential-oil-of-psidium-guajava-l-leaves-from-different-geographic-regions-in-china
#10
Lu Wang, Yanan Wu, Tao Huang, Kan Shi, Zhenqiang Wu
Hydrodistilled essential oils (EO) of Psidium guajava L. leaves from different regions in China were analyzed by GC and GC/MS. The samples from Guangdong province displayed high EO yields (0.61-0.75%, v/w). A total of 50 components, representing over 98.00% of the EOs, were identified and semi-quantitatived. The major constituents of EOs included β-caryophyllen (17.17-31.38%), γ-gurjunene (9.17-15.22%), τ-cadinol (1.35-10.02%) and calamenene (2.13-7.80%). The terpenoids in all sample oils were dominated by sesquiterpenes hydrocarbons (70...
June 15, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/28615852/therapecutic-efficacy-of-the-leaf-extract-of-croton-joufra-roxb-against-experimental-cestodiasis-in-rats
#11
Shyamalima Gogoi, Arun K Yadav
The leaves of Croton joufra have been used as a traditional medicine in Assam (Northeast India) to treat the intestinal helminthic infections. The aim of this study was to establish the in vitro and in vivo anthelmintic efficacy of the leaf extract of this plant on Hymenolepis diminuta, a zoonotic tapeworm. The plant extract was also screened for its chemical constituents. The in vitro anthelmintic efficacy of the plant was evaluated by physical motility test on adult cestodes, following their exposure to 10, 20, 30 mg/ml concentrations of the crude leaf extract, while the in vivo effect was determined based on the eggs per gram (EPG) counts and worm recovery rates, using an experimentally induced model of H...
June 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28615048/integrated-metabolome-and-transcriptome-analysis-of-magnolia-champaca-identifies-biosynthetic-pathways-for-floral-volatile-organic-compounds
#12
Savitha Dhandapani, Jingjing Jin, Vishweshwaran Sridhar, Rajani Sarojam, Nam-Hai Chua, In-Cheol Jang
BACKGROUND: Magnolia champaca, commonly known as champak is a well-known tree due to its highly fragrant flowers. Champak floral scent is attributed to a complex mix of volatile organic compounds (VOCs). These aromatic flowers are widely used in flavors and fragrances industry. Despite its commercial importance, the VOC biosynthesis pathways in these flowers are largely unknown. Here, we combine metabolite and RNA sequencing (RNA-seq) analyses of fully opened champak flowers to discover the active VOC biosynthesis pathways as well as floral scent-related genes...
June 14, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28613253/terpenoids-from-platostoma-rotundifolium-briq-a-j-paton-alter-the-expression-of-quorum-sensing-related-virulence-factors-and-the-formation-of-biofilm-in-pseudomonas-aeruginosa-pao1
#13
Tsiry Rasamiravaka, Jérémie Ngezahayo, Laurent Pottier, Sofia Oliveira Ribeiro, Florence Souard, Léonard Hari, Caroline Stévigny, Mondher El Jaziri, Pierre Duez
Platostoma rotundifolium (Briq.) A. J. Paton aerial parts are widely used in Burundi traditional medicine to treat infectious diseases. In order to investigate their probable antibacterial activities, crude extracts from P. rotundifolium were assessed for their bactericidal and anti-virulence properties against an opportunistic bacterial model, Pseudomonas aeruginosa PAO1. Whereas none of the tested extracts exert bacteriostatic and/or bactericidal proprieties, the ethyl acetate and dichloromethane extracts exhibit anti-virulence properties against Pseudomonas aeruginosa PAO1 characterized by an alteration in quorum sensing gene expression and biofilm formation without affecting bacterial viability...
June 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28603132/airways-and-vascular-smooth-muscles-relaxant-activities-of-gaultheria-trichophylla
#14
Fiaz Alam, Qazi Najumus Saqib, Abdul Jabbar Shah
The aim of this experimental work was to explore the potential pharmacological activities of Gaultheria trichophylla Royle in hyperactive respiratory and vascular conditions. Gaultheria trichophylla was extracted with solvents, phytochemical detection tests were performed, and rabbit trachea and aorta strips were used to evaluate its effects on airways and vascular smooth muscles. Qualitative phytochemical tests showed the presence of flavonoids, alkaloids, anthraquinones, saponins, terpenoids, and condensed tannins...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28599704/new-horizons-in-the-extraction-of-bioactive-compounds-using-deep-eutectic-solvents-a-review
#15
REVIEW
Mohamad Hamdi Zainal-Abidin, Maan Hayyan, Adeeb Hayyan, Natesan Subramanian Jayakumar
With the rapid development of ionic liquid analogues, termed 'deep eutectic solvents' (DESs), and their application in a wide range of chemical and biochemical processes in the past decade, the extraction of bioactive compounds has attracted significant interest. Recently, numerous studies have explored the extraction of bioactive compounds using DESs from diverse groups of natural sources, including animal and plant sources. This review summarizes the-state-of-the-art effort dedicated to the application of DESs in the extraction of bioactive compounds...
August 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28590124/terpenoids-from-euphorbia-soongarica-and-their-multidrug-resistance-reversal-activity
#16
Jie Gao, Haji A Aisa
Ten new terpenoids, including five diterpenoids (1-5), three nortriterpenoids (6-8), and two triterpenoids (9, 10), and 15 known terpenoids (11-25) were isolated from an acetone extract of Euphorbia soongarica. Sooneuphoramine (1) is the first example of a euphoractine B-type diterpenoid alkaloid, while sooneuphanones A-C (6-8) are rare nortriterpenoids from the Euphorbia genus. The isolated terpenoids were tested for their cytotoxicity and multidrug resistance (MDR) reversal activity, 10 of which showed moderate cytotoxicity against the KB and KBv200 cell lines, while 11 compounds exhibited P-gp modulating potential...
June 7, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28589297/sulfate-turpentine-a-resource-of-tick-repellent-compounds
#17
Fredrik Schubert, Katinka Pålsson, Ellen Santangelo, Anna-Karin Borg-Karlson
Compounds with tick (Ixodes ricinus) repellent properties were isolated from sulfate turpentine consisting of Norway spruce (80%) and Scots pine (20%) from southern Sweden. The turpentine was divided into two fractions by distillation under reduced pressure resulting in one monoterpene hydrocarbon fraction and a residual containing higher boiling terpenoids. The monoterpene fraction was further oxidized with SeO2 to obtain oxygenated monoterpenes with potential tick repellent properties. The oxidized fraction and the high boiling distillation residual were each separated by medium pressure liquid chromatography...
June 6, 2017: Experimental & Applied Acarology
https://www.readbyqxmd.com/read/28585451/a-three-way-transcriptomic-interaction-study-of-a-biocontrol-agent-clonostachys-rosea-a-fungal-pathogen-helminthosporium-solani-and-a-potato-host-solanum-tuberosum
#18
Erik Lysøe, Merete W Dees, May Bente Brurberg
Helminthosporium solani causes silver scurf, which affects the quality of potato. The biocontrol agent Clonostachys rosea greatly limited the severity of silver scurf symptoms and amount of H. solani genomic DNA in laboratory experiments. Transcriptomic analysis during interaction showed that H. solani gene expression was highly reduced when coinoculated with the biocontrol agent C. rosea, whereas gene expression of C. rosea was clearly boosted as a response to the pathogen. The most notable upregulated C. rosea genes were those encoding proteins involved in cellular response to oxidative stress, proteases, G-protein signaling, and the methyltransferase LaeA...
June 6, 2017: Molecular Plant-microbe Interactions: MPMI
https://www.readbyqxmd.com/read/28580785/applications-of-nonenzymatic-catalysts-to-the-alteration-of-natural-products
#19
Christopher R Shugrue, Scott J Miller
The application of small molecules as catalysts for the diversification of natural product scaffolds is reviewed. Specifically, principles that relate to the selectivity challenges intrinsic to complex molecular scaffolds are summarized. The synthesis of analogues of natural products by this approach is then described as a quintessential "late-stage functionalization" exercise wherein natural products serve as the lead scaffolds. Given the historical application of enzymatic catalysts to the site-selective alteration of complex molecules, the focus of this Review is on the recent studies of nonenzymatic catalysts...
June 5, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/28580151/transcriptomic-and-metabolomic-analyses-of-cucumber-fruit-peels-reveal-a-developmental-increase-in-terpenoid-glycosides-associated-with-age-related-resistance-to-phytophthora-capsici
#20
Ben N Mansfeld, Marivi Colle, Yunyan Kang, A Daniel Jones, Rebecca Grumet
The oomycete, Phytophthora capsici, infects cucumber (Cucumis sativus L.) fruit. An age-related resistance (ARR) to this pathogen was previously observed in fruit of cultivar 'Vlaspik' and shown to be associated with the peel. Young fruits are highly susceptible, but develop resistance at ~10-12 days post pollination (dpp). Peels from resistant (16 dpp) versus susceptible (8 dpp) age fruit are enriched with genes associated with defense, and methanolic extracts from resistant age peels inhibit pathogen growth...
2017: Horticulture Research
keyword
keyword
111953
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"