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Thyroid cancer epidemiology

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https://www.readbyqxmd.com/read/29241201/cot-death-history-of-an-iatrogenic-disaster
#1
Michael Obladen
Since antiquity, cot death has been explained as accidental suffocation, overlaying, or smothering. Parents were blamed for neglect or drunkenness. A cage called arcuccio was invented around 1570 to protect the sleeping infant. Up to the 19th century, accidents were registered as natural causes of death. From 1830, accidental suffocation became unacceptable for physicians and legislators, and "natural" explanations for the catastrophe were sought, with parents being consoled rather than blamed. Two assumed causes had serious consequences: thymus hyperplasia was irradiated, causing thyroid cancer, and the concept of central apnea was widely accepted, which led to home monitors and distracted from epidemiological evidence...
December 15, 2017: Neonatology
https://www.readbyqxmd.com/read/29238222/the-burden-of-selected-cancers-in-the-us-health-behaviors-and-health-care-resource-utilization
#2
Laura Iadeluca, Jack Mardekian, Pratibha Chander, Markay Hopps, Geoffrey T Makinson
Objective: To characterize the disease burden among survivors of those cancers having the highest incidence in the US. Methods: Adult (≥18 years) survivors of the 11 most frequently diagnosed cancers were identified from publically available data sources, including the Surveillance Epidemiology and End Results 9 1973-2012, National Health Interview Survey 2013, and the Medical Expenditure Panel Survey 2011. Chi-square tests and one-way analyses of variance were utilized to assess differences between cancer survivors and non-cancer controls in behavioral characteristics, symptoms and functions, preventative screenings, and health care costs...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/29185020/the-positive-lymph-node-number-and-postoperative-n-staging-used-to-estimate-survival-in-patients-with-differentiated-thyroid-cancer-results-from-the-surveillance-epidemiology-and-end-results-dataset-1988-2008
#3
Wen-Jun Wei, Zhong-Wu Lu, Duo Wen, Tian Liao, Duan-Shu Li, Yu Wang, Yong-Xue Zhu, Zhuo-Ying Wang, Yi Wu, Yu-Long Wang, Qing-Hai Ji
BACKGROUND: Lymph node metastasis is important when evaluating the prognosis of patients with differentiated thyroid cancer (DTC). However, the current N-staging system cannot fully reflect the clinical significance of cervical lymph node metastasis in DTC. In this study, we employed Surveillance, Epidemiology, and End Results (SEER)-registered DTC cases with lymph node metastasis to determine whether the positive lymph node number (PLNN) could be used to improve stratification of patients in terms of survival...
November 28, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29184536/insulin-resistance-any-role-in-the-changing-epidemiology-of-thyroid-cancer
#4
REVIEW
Roberta Malaguarnera, Veronica Vella, Maria Luisa Nicolosi, Antonino Belfiore
In the past few decades, the incidence of thyroid cancer (TC), namely of its papillary hystotype (PTC), has shown a steady increase worldwide, which has been attributed at least in part to the increasing diagnosis of early stage tumors. However, some evidence suggests that environmental and lifestyle factors can also play a role. Among the potential risk factors involved in the changing epidemiology of TC, particular attention has been drawn to insulin-resistance and related metabolic disorders, such as obesity, type 2 diabetes, and metabolic syndrome, which have been also rapidly increasing worldwide due to widespread dietary and lifestyle changes...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29156816/mixed-subtype-thyroid-cancer-a-surveillance-epidemiology-and-end-results-database-analysis
#5
Chunping Liu, Qiuyang Zhao, Zhi Li, Shuntao Wang, Yiquan Xiong, Zeming Liu, Tao Huang
The prognosis of patients with mixed subtype thyroid cancer (MSTC) is unclear. The present study compared the prognoses of MSTC, papillary thyroid cancer (PTC), and follicular thyroid cancer (FTC) to provide a new perspective regarding the treatment guidelines for these diseases. We evaluated data from patients with thyroid cancer who were included in the Surveillance, Epidemiology, and End Results database between 2004 and 2013. Patient mortality was evaluated using Cox proportional hazards regression analyses and Kaplan-Meier analyses with log-rank tests...
October 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29123502/anaplastic-thyroid-cancer-in-sicily-the-role-of-environmental-characteristics
#6
Martina Tavarelli, Pasqualino Malandrino, Paolo Vigneri, Pierina Richiusa, Adele Maniglia, Maria A Violi, Giulia Sapuppo, Veronica Vella, Gabriella Dardanoni, Riccardo Vigneri, Gabriella Pellegriti
Background: Anaplastic thyroid cancer (ATC) is a rare but extremely aggressive cancer of the thyroid, contributing up to 30-40% of thyroid cancer-specific mortality. We analyzed ATC characteristics and survival rates in Sicily to evaluate the possible influence of environmental factors. With this aim, data regarding ATC incidences in urban/rural and industrial, iodine-deficient, and volcanic vs control areas were compared in Sicily as well as ATC data from Sicily and USA. Methods: Using the Sicilian Register of Thyroid Cancer (SRTC) database incidence, age, gender, tumor size and histotype, extrathyroidal extension, stage, and coexistence with pre-existing differentiated thyroid cancer (DTC) were evaluated in different areas of Sicily and also compared with Surveillance Epidemiology and End Results data in USA...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29108330/surgical-management-for-follicular-variant-of-papillary-thyroid-carcinoma
#7
Jianing Tang, Deguang Kong, Lupin Bu, Gaosong Wu
Background and Aims: For most patients with follicular variant of papillary thyroid carcinoma (FVPTC), surgery is required, while the surgical management remains controversial. We aim to further understanding of treatment of FVPTC and to determine whether specific features could be identified for the decision of surgical strategy. Materials and Methods: Data were obtained from the Surveillance, Epidemiology, and End Results (SEER) Program database during 2003 and 2013...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29108325/ratio-of-positive-lymph-nodes-the-prognostic-value-in-stage-iv-thyroid-cancer
#8
Tingyin Jiang, Chunling Huang, Yuan Xu, Yingrui Su, Guanjie Zhang, Long Xie, Liqun Huang, Shuchun You, Jinshun Zha
To assess the prognostic value of lymph node ratio (LNR) in patients with stage IV thyroid cancer based on the Surveillance, Epidemiology, and End Results (SEER) database. A total of 4,940 eligible patients were included for the analysis. Kaplan-Meier survival analysis and Cox proportional hazard regression were used to reveal the effect of LNR on overall survival (OS) and disease specific survival (DSS). The optimal cut-off value of LNR for predicting OS and DSS was determined by the time-dependent Receiver Operating Characteristic analysis...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29108240/nationwide-cohort-study-on-the-epidemiology-and-survival-outcomes-of-thyroid-cancer
#9
Fu-Chao Liu, Huan-Tang Lin, Shu-Fu Lin, Chang-Fu Kuo, Ting-Ting Chung, Huang-Ping Yu
In the past three decades, the thyroid cancer incidence has surged globally. Herein, the Taiwan National Health Insurance database was used to identify thyroid cancer patients and to estimate the prevalence and incidence of thyroid cancer during 1997-2012. The Taiwan Cancer Registry and the National Death Registry databases were crosslinked to obtain information on the histological subtypes and survival rates. Joinpoint regression analysis was used for estimating the average annual percentage changes (APCs) in prevalence, incidence, and survival...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29104287/risk-of-developing-chronic-myeloid-neoplasms-in-well-differentiated-thyroid-cancer-patients-treated-with-radioactive-iodine
#10
R J Molenaar, C Pleyer, T Radivoyevitch, S Sidana, A Godley, A S Advani, A T Gerds, H E Carraway, M Kalaycio, A Nazha, D Adelstein, C Nasr, D Angelini, J P Maciejewski, N Majhail, M A Sekeres, S Mukherjee
Exposure to ionizing radiation increases the risk of myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN), but such risks are not known in well-differentiated thyroid cancer (WDTC) patients treated with radioactive iodine (RAI). A total of 148 215 WDTC patients were identified from Surveillance Epidemiology and End Results (SEER) registries between 1973 and 2014, of whom 54% underwent definitive thyroidectomy and 46% received adjuvant RAI. With a median follow-up of 6.6 years, 77 and 66 WDTC patients developed MDS and MPN, respectively...
November 6, 2017: Leukemia: Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K
https://www.readbyqxmd.com/read/29100371/do-patients-with-oxyphilic-cell-papillary-thyroid-carcinoma-have-a-poor-prognosis-analysis-of-the-surveillance-epidemiology-and-end-results-database-2004-2013-with-propensity-score-matching
#11
Chunping Liu, Qiuyang Zhao, Wen Zeng, Chen Chen, Jie Ming, Shuntao Wang, Yiquan Xiong, Chao Zhang, Tianwen Chen, Zeming Liu, Tao Huang
The prognosis of oxyphilic cell papillary thyroid carcinoma (OCPTC) remains unclear. The aim of this study was to investigate the prognosis of OCPTC and provide a new perspective on treatment guidelines for these patients. We investigated a large cohort of DTC patients from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2013. Patient mortality was examined by Kaplan-Meier analyses with log-rank tests and Cox proportional hazards regression analyses. In the study cohort, the rate of cancer-specific mortality per 1000 person-years for OCPTC was lower than that for classic papillary thyroid cancer (CPTC) and follicular thyroid cancer (FTC)...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29050318/unanticipated-prognosis-of-differential-thyroid-cancer-patients-with-t0-stage-analysis-of-the-seer-database-2004-2013
#12
Chunping Liu, Jie Ming, Wen Zeng, Shuntao Wang, Yiquan Xiong, Qiuyang Zhao, Xingjie Yin, Zeming Liu, Tao Huang
The prognosis of T0 stage differentiated thyroid cancer (DTC) remains unclear. This study aimed to investigate the prognosis of T0 stage DTC patients to provide a new perspective on treatment guidelines for these patients. We investigated a large cohort of DTC patients from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2013. Patient survival curves were examined by Kaplan-Meier analyses with log-rank tests and Cox proportional hazards regression analyses. In the study cohort, the rate of cancer-specific mortality per 1000 person-years for T0 was higher than T1-T3, but lower than T4...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29038151/obesity-and-cancer-evidence-impact-and-future-directions
#13
REVIEW
Graham A Colditz, Lindsay L Peterson
BACKGROUND: Mounting evidence, particularly from prospective epidemiologic studies but with additional support from animal models and mechanistic studies, supported conclusions in 2016 by the International Agency for Research on Cancer (IARC)(3) in their review of the preventive effects of weight control on cancer risk. CONTENT: The workgroup concluded that obesity is causally related to cancer at 13 anatomic sites (esophagus: adenocarcinoma; gastric cardia; colon and rectum; liver; gallbladder; pancreas; breast: postmenopausal; uterine endometrial; ovary; kidney: renal cell; meningioma; thyroid; and multiple myeloma)...
October 16, 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/29019328/second-primary-tumors-associated-with-breast-cancer-kuwait-cancer-control-center-experience
#14
Salah Fayaz, Gerges Attia Demian, Heba El-Sayed Eissa, Sadeq Abuzalouf
OBJECTIVES: To review the clinico-epidemiologic characteristics of patients who presented with two or more primary cancers, one of which was breast cancer (BC) and to develop a follow-up program for the high risk patients. PATIENTS AND METHODS: Patients who were diagnosed with BC and one or more non breast cancer (NBC) were retrospectively reviewed. Medical files were retrieved and epidemiological as well as clinical data were analyzed. RESULTS: Sixty-two patients were retrieved...
September 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28983950/epidemiology-and-comorbidities-of-patients-with-chronic-urticaria-in-korea-a-nationwide-population-based-study
#15
Bo Ri Kim, Seungkeol Yang, Jee Woong Choi, Chong Won Choi, Sang Woong Youn
Few population-based studies have focused on the epidemiology and comorbidities of chronic urticaria (CU) or chronic spontaneous urticaria (CSU). The objective of this study was to obtain information on the epidemiology and comorbidities associated with CU and CSU in Korea. We conducted a cross-sectional analysis using a national health insurance database. An algorithm based on the International Classification of Diseases, 10th revision, was used for the identification of patients with CU and CSU, and an age-sex adjusted logistic regression model was used to assess the risk of comorbidities in these patients...
October 6, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28977647/attributable-risk-fraction-of-four-lifestyle-risk-factors-of-thyroid-cancer-a-meta-analysis
#16
Hajar Sadeghi, Mohammad Rafei, Masoud Bahrami, AliAkbar Haghdoost, Yazdan Shabani
Background: Lifestyle risk factors such as obesity, overweight, smoking and radiation exposure related to thyroid cancer. This study estimated the amount of excess risk that attributed to risk factors. Methods: Major electronic databases were searched until February 2016. Epidemiological studies addressing the association between lifestyle risk factors and thyroid cancer were enrolled. The results were expressed as ARF with 95% confidence intervals (CIs) using a random-effects-model...
August 9, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28954584/lessons-from-fukushima-latest-findings-of-thyroid-cancer-after-the-fukushima-nuclear-power-plant-accident
#17
Shunichi Yamashita
The increase in risk for late-onset thyroid cancer due to radiation exposure is a potential health effect after a nuclear power plant accident mainly due to the release of radioiodine in fallout. The risk is particularly elevated in those exposed during infancy and adolescence. To estimate the possibility and extent of thyroid cancer occurrence after exposure, it is of utmost importance to collect and analyze epidemiological information providing the basis for evaluation of radiation risk, and to consider radiobiology and molecular genetics...
September 27, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28900207/reevaluating-the-prognostic-significance-of-male-gender-for-papillary-thyroid-carcinoma-and-microcarcinoma-a-seer-database-analysis
#18
Chunping Liu, Tianwen Chen, Wen Zeng, Shuntao Wang, Yiquan Xiong, Zeming Liu, Tao Huang
The prognostic significance of gender remains controversial for papillary thyroid carcinoma (PTC). In this study, we investigated the associations between gender and prognosis in a large cohort of patients with PTC or PTMC that was diagnosed in 2010-2013 and recorded in the Surveillance, Epidemiology, and End Results cancer registry. The mean ± standard deviation duration of survival for all patients with PTC during the study period was 21.47 ± 14.04 months. In Kaplan-Meier analyses of the entire cohort of PTC patients, survival curves for all-cause death and cancer-specific death declined more sharply for men than for women...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28878202/predicting-organ-specific-risk-interactions-between-radiation-and-chemotherapy-in-secondary-cancer-survivors
#19
Venkata S K Manem, Clemens Grassberger, Harald Paganetti
Several studies have shown that pediatric patients have an increased risk of developing a secondary malignancy several decades after treatment with radiotherapy and chemotherapy. In this work, we use a biologically motivated mathematical formalism to estimate the relative risks of breast, lung and thyroid cancers in childhood cancer survivors due to concurrent therapy regimen. This model specifically includes possible organ-specific interaction between radiotherapy and chemotherapy. The model predicts relative risks for developing secondary cancers after chemotherapy in breast, lung and thyroid tissues, and compared with the epidemiological data...
September 6, 2017: Cancers
https://www.readbyqxmd.com/read/28862484/a-population-based-study-of-prognosis-and-survival-in-patients-with-second-primary-thyroid-cancer-after-hodgkin-lymphoma
#20
Amit K Chowdhry, Chunkit Fung, Varun K Chowdhry, Derek Bergsma, Sughosh Dhakal, Louis S Constine, Michael T Milano
Hodgkin lymphoma (HL) survivors are at increased risk of thyroid cancer (TC). We sought to determine whether increased risks of high-risk pathology or mortality are seen with thyroid cancer after HL (HL-TC) compared with first primary thyroid cancer (TC-1). From the Surveillance, Epidemiology and End Results (SEER) registry, we compared patient and tumor characteristics as well as survival outcomes between HL-TC and TC-1 and fit a multivariable Cox model to assess for a possible association between HL history and overall survival after TC...
September 1, 2017: Leukemia & Lymphoma
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