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Thyroid cancer epidemiology

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https://www.readbyqxmd.com/read/27917722/racial-disparities-in-papillary-thyroid-microcarcinoma-survival
#1
U C Megwalu, A T Saini
OBJECTIVE: To evaluate the impact of race on survival in patients with papillary thyroid microcarcinoma. METHODS: The study cohort included 17 668 patients diagnosed with papillary thyroid microcarcinoma between 1988 and 2009, identified in the Surveillance, Epidemiology, and End Results 18 database of the National Cancer Institute. RESULTS: Black patients had lower overall survival than other racial groups (p < 0.001). Black patients had significantly worse overall survival (hazard ratio = 2...
December 5, 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27903497/association-between-screening-and-the-thyroid-cancer-epidemic-in-south-korea-evidence-from-a-nationwide-study
#2
Sohee Park, Chang-Mo Oh, Hyunsoon Cho, Joo Young Lee, Kyu-Won Jung, Jae Kwan Jun, Young-Joo Won, Hyun-Joo Kong, Kui Son Choi, You Jin Lee, Jin Soo Lee
OBJECTIVE:  To investigate whether screening for thyroid cancer led to the current "epidemic" in South Korea. DESIGN:  Review of the medical records of nationally representative samples of patients with a diagnosis of thyroid cancer in 1999, 2005, and 2008. SETTING:  Sample cases were randomly selected from South Korea's nationwide cancer registry, using a systematic sampling method after stratification by region. PARTICIPANTS:  5796 patients with thyroid cancer were included (891 in 1999, 2355 in 2005, and 2550 in 2008)...
November 30, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27895436/rising-incidence-of-thyroid-cancer-in-serbia
#3
N Slijepcevic, V Zivaljevic, I Paunovic, A Diklic, Perisic Zivkovic, D Miljus, A Grgurevic, S Sipetic
BACKGROUND: In the past decade, the incidence of thyroid cancer (TC) has shown a stable increase, for both sexes, in many parts of the world at a rate faster than for any other type of malignancy. The aim of our study was to analyze and report changes in TC incidence in Serbia, as well as to evaluate potential reasons for these changes. So far, the incidence of TC in Serbia has not been reported. MATERIAL AND METHODS: This is a retrospective descriptive epidemiological study of TC data from the Cancer Register for Serbia for a ten year period, from 1999 to 2008...
January 2016: Hippokratia
https://www.readbyqxmd.com/read/27886135/soy-and-health-update-evaluation-of-the-clinical-and-epidemiologic-literature
#4
REVIEW
Mark Messina
Soyfoods have long been recognized as sources of high-quality protein and healthful fat, but over the past 25 years these foods have been rigorously investigated for their role in chronic disease prevention and treatment. There is evidence, for example, that they reduce risk of coronary heart disease and breast and prostate cancer. In addition, soy alleviates hot flashes and may favorably affect renal function, alleviate depressive symptoms and improve skin health. Much of the focus on soyfoods is because they are uniquely-rich sources of isoflavones...
November 24, 2016: Nutrients
https://www.readbyqxmd.com/read/27885302/cancers-of-the-thyroid-overview-and-statistics-in-the-united-states-and-oklahoma
#5
Munim H Deen, Kaitlin M Burke, Amanda Janitz, Janis Campbell
Recent studies have shown an apparent increase in thyroid cancer in the United States. Whether is due to an actual increase or increased screening is disputed. We analyzed thyroid cancer incidence and mortality across age and racial groups in Oklahoma (using data from the Oklahoma Central Cancer Registry) against Surveillance, Epidemiology, and End Results (SEER) program national data - using SEER*Stat software for mortality. In the US and Oklahoma, females had a higher AAIR compared to males, but it was lower in Oklahoma than in the US (Females: US 15...
July 2016: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/27861148/paradoxes-in-thyroid-carcinoma-treatment-analysis-of-the-seer-database-2010-2013
#6
Ping Zhou, Shuangming Tian, Jiale Li, Yongfeng Zhao, Wengang Liu, Yan Zhang, Zheyu Hu
Thyroid cancer is a common malignant disease with high survival rate (98.1%, 2006-2012, Surveillance Epidemiology and End Results (SEER) program). In this study, we investigated the treatment paradoxes in thyroid T0 and micro-carcinoma patients. 48,234 thyroid carcinoma patients were identified from 2010 to 2013 in SEER*Stat database (version 8.2.1) released in 2016. Survival analysis showed a significantly lower thyroid carcinoma-specific survival in T0 patients compared with T1-T3 patients. In propensity score analysis, T0 patients had a similar survival curve with T1-T3 patients when lymph node and distant metastasis stages were matched...
November 16, 2016: Oncotarget
https://www.readbyqxmd.com/read/27843342/the-danish-head-and-neck-cancer-database
#7
REVIEW
Jens Overgaard, Aleksandar Jovanovic, Christian Godballe, Jesper Grau Eriksen
AIM OF THE DATABASE: The Danish Head and Neck Cancer database is a nationwide clinical quality database that contains prospective data collected since the early 1960s. The overall aim of this study was to describe the outcome of the national strategy for multidisciplinary treatment of head and neck cancer in Denmark and to create a basis for clinical trials. STUDY POPULATION: The study population consisted of all Danish patients referred for treatment of squamous cell carcinoma of the larynx, pharynx, oral cavity, or neck nodes from unknown primary or any histopathological type (except lymphoma) of cancer in the nasal sinuses, salivary glands, or thyroid gland (corresponding to the International Classification of Diseases, tenth revision, classifications C...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27842913/trends-in-the-presentation-treatment-and-survival-of-patients-with-medullary-thyroid-cancer-over-the-past-30%C3%A2-years
#8
Reese W Randle, Courtney J Balentine, Glen E Leverson, Jeffrey A Havlena, Rebecca S Sippel, David F Schneider, Susan C Pitt
BACKGROUND: The impact of recent medical advances on disease presentation, extent of operation, and disease-specific survival for patients with medullary thyroid cancer is unclear. METHODS: We used the Surveillance, Epidemiology, and End Results registry to compare trends over 3 time periods, 1983-1992, 1993-2002, and 2003-2012. RESULTS: There were 2,940 patients diagnosed with medullary thyroid cancer between 1983 and 2012. The incidence of medullary thyroid cancer increased during this time period from 0...
November 11, 2016: Surgery
https://www.readbyqxmd.com/read/27836371/predictors-of-nodal-metastasis-in-pediatric-differentiated-thyroid-cancer
#9
Jina Kim, Zhifei Sun, Mohamed A Adam, Obinna O Adibe, Henry E Rice, Sanziana A Roman, Elisabeth T Tracy
BACKGROUND/PURPOSE: There are limited data identifying risk factors for nodal metastasis in children with differentiated thyroid cancer. METHODS: The 1998-2011 Surveillance, Epidemiology, and End Results Program database was queried for patients ≤18years of age diagnosed with differentiated thyroid cancer who underwent nodal examination. Patients were grouped by absence or presence of nodal metastasis. Multivariable logistic regression methods were used to identify independent risk factors for nodal metastasis...
October 27, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27817857/-cancer-in-adolescents-and-young-adults-in-france-epidemiology-and-pathways-of-care
#10
Emmanuel Desandes, Brigitte Lacour, Jacqueline Clavel
In adolescents and young adults (AYA), cancers are rare but represent the third significant cause of death. The aim of this paper was to investigate epidemiological data and pathways of care of AYA in France. During the 2000-2008 period, overall age-standardized incidence rates (ASR) were 254.1/10(6) in 15-24-year-olds. The most frequently diagnosed cancers in male AYA were malignant gonadal germ-cell tumors and Hodgkin's lymphoma, and were melanoma, thyroid carcinoma and Hodgkin's disease in females. The ASR appeared stable over time...
November 3, 2016: Bulletin du Cancer
https://www.readbyqxmd.com/read/27775261/the-epidemiologic-status-of-gynecologic-cancer-in-thailand
#11
Sarikapan Wilailak, Nuttapong Lertchaipattanakul
Between the years of 2010-2012, it was estimated there were a total of 112,392 new cases of cancers in Thailand, thus, the total age-standardized rate (ASR) per 100,000 is 137.6. In regards to the most prevalent types of cancer in female, breast cancer has the highest ASR, followed by cervical cancer (ASR=14.4); liver and bile duct cancer; colon and rectum cancer; trachea, bronchus and lung cancer; ovarian cancer (ASR=6.0); thyroid cancer; non-Hodgkin lymphoma and uterine cancer (ASR=4.3). The trend of cervical cancer in Thailand is decreasing, one key factor in making this possible was the employment of dual tract strategy (Pap smear and visual inspection with acetic acid [VIA]) by the government in 2005...
November 2016: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/27762670/estimation-of-second-primary-cancer-risk-after-treatment-with-radioactive-iodine-for-differentiated-thyroid-carcinoma
#12
Nilton Lavatori Corrêa, Lidia Vasconcellos de Sá, Rossana Corbo Ramalho de Mello
BACKGROUND: An increase in the incidence of second primary cancers is the late effect of greatest concern that could occur in differentiated thyroid carcinoma (DTC) patients treated with radioactive iodine (RAI). The decision to treat a patient with RAI should therefore incorporate a careful risk-benefit analysis. The objective of this work was to adapt the risk-estimation models developed by the Biological Effects of Ionizing Radiation Committee to local epidemiological characteristics in order to assess the carcinogenesis risk from radiation in a population of Brazilian DTC patients treated with RAI...
November 21, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27737324/surgical-treatment-for-thyroid-carcinoma-retrospective-study-with-811-patients-in-a-brazilian-tertiary-hospital
#13
Beatriz G Cavalheiro, Leandro L Matos, Ana Kober N Leite, Marco Aurélio V Kulcsar, Claudio R Cernea, Lenine G Brandão
Objective: The aim of the present study was to describe the epidemiologic data, histological type, treatment and follow-up of the 811 patients treated for thyroid cancer in Instituto do Câncer do Estado de São Paulo (ICESP) over 5 years. Materials and methods: Retrospective analyses of electronic chart information. Results: There were 679 cases (83.7%) of papillary thyroid cancer, 61 (7.5%) of follicular carcinoma, 54 (6.7%) of medullary carcinoma, 11 (1...
October 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27729373/integration-of-a-radiation-biomarker-into-modeling-of-thyroid-carcinogenesis-and-post-chernobyl-risk-assessment
#14
Jan Christian Kaiser, Reinhard Meckbach, Markus Eidemüller, Martin Selmansberger, Kristian Unger, Viktor Shpak, Maria Blettner, Horst Zitzelsberger, Peter Jacob
Strong evidence for the statistical association between radiation exposure and disease has been produced for thyroid cancer by epidemiological studies after the Chernobyl accident. However, limitations of the epidemiological approach in order to explore health risks especially at low doses of radiation appear obvious. Statistical fluctuations due to small case numbers dominate the uncertainty of risk estimates. Molecular radiation markers have been searched extensively to separate radiation-induced cancer cases from sporadic cases...
December 2016: Carcinogenesis
https://www.readbyqxmd.com/read/27619933/excess-weight-tied-to-eight-more-cancers
#15
(no author information available yet)
According to an analysis of more than 1,000 epidemiologic studies, being overweight or obese increases the risk of eight cancers: stomach, liver, gallbladder, pancreas, ovary, and thyroid cancers, multiple myeloma, and meningioma. Researchers initially identified five other malignancies linked to excess body weight in 2002, including breast and endometrial cancers.
October 2016: Cancer Discovery
https://www.readbyqxmd.com/read/27619041/pediatric-thyroid-cancer-an-update-from-the-seer-database-2007-2012
#16
Sarah Dermody, Andrew Walls, Earl H Harley
OBJECTIVE: To update the medical literature regarding the incidence, disease specific survival, and treatment modalities utilized in pediatric patients diagnosed with thyroid carcinomas. STUDY DESIGN: Cross Sectional Analysis of a National Database. STUDY SETTING: SEER Database. METHODS: The National Cancer Institute's Surveillance Epidemiology and End Results (SEER) Database was queried for all cases of pediatric thyroid cancer between the years 2007 and 2012...
October 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27601922/risk-prediction-and-clinical-model-building-for-lymph-node-metastasis-in-papillary-thyroid-microcarcinoma
#17
Dao-Zhe Lin, Ning Qu, Rong-Liang Shi, Zhong-Wu Lu, Qing-Hai Ji, Wei-Li Wu
The surgical management of papillary thyroid microcarcinoma (PTMC), especially regarding the necessity of central/lateral lymph node dissection, remains controversial. This study investigated the clinicopathologic factors predictive of lymph node metastasis (LNM) in patients diagnosed with PTMC. Multivariate logistic regression analysis was used for PTMC patients identified from the Surveillance, Epidemiology, and End Results database who were treated by surgery between 2002 and 2012, to determine the association of clinicopathologic factors with LNM...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27588396/metastatic-lymph-node-ratio-can-further-stratify-risk-for-mortality-in-medullary-thyroid-cancer-patients-a-population-based-analysis
#18
Ning Qu, Rong-Liang Shi, Zhong-Wu Lu, Tian Liao, Duo Wen, Guo-Hua Sun, Duan-Shu Li, Qing-Hai Ji
Medullary thyroid cancer (MTC) has a propensity to cervical lymph node metastases (LNM). Recent studies have shown that both the number of involved lymph nodes (LNs) and the metastatic lymph node ratio (MLNR) confer prognostic information. This study was to determine the predictive value of MLNR on cancer-specific survival (CSS) in SEER (Surveillance, Epidemiology and End Results)-registered MTC patients treated with thyroidectomy and lymphadenectomy between 1991 and 2012, investigate the cutoff points for MLNR in stratifying risk of mortality and provide evidence for selection of appropriate treatment strategies...
August 31, 2016: Oncotarget
https://www.readbyqxmd.com/read/27574443/tumor-size-interpretation-for-predicting-cervical-lymph-node-metastasis-using-a-differentiated-thyroid-cancer-risk-model
#19
Rong-Liang Shi, Ning Qu, Shu-Wen Yang, Ben Ma, Zhong-Wu Lu, Duo Wen, Guo-Hua Sun, Yu Wang, Qing-Hai Ji
Lymph node metastasis (LNM) is common in differentiated thyroid cancer (DTC), but management of clinically negative DTC is controversial. This study evaluated primary tumor size as a predictor of LNM. Multivariate logistic regression analysis was used for DTC patients who were treated with surgery between 2002 and 2012 in the Surveillance, Epidemiology, and End Results (SEER) database, to determine the association of tumor size at 10 mm increments with LNM. A predictive model was then developed to estimate the risk of LNM in DTC, using tumor size and other clinicopathological characteristics identified from the multivariate analysis...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27566096/synchronous-and-metachronous-malignancies-after-malignant-struma-ovarii-in-the-seer-database
#20
Andrea Sisti, Juri Tassinari, Giuseppe Nisi, Luca Grimaldi, Giovanni Sisti, Mariarosaria DI Tommaso, Massimiliano Fambrini
BACKGROUND/AIM: Second primary tumors (SPTs) often occur, either synchronous or metachronous. Struma ovarii is a rare ovarian tumor represented by thyroid tissue in the ovary. Among other factors, production of thyroid hormones by the tumor or a shared genetic predisposition can further influence the development of SPTs. The occurrence of SPT, either synchronous or metachronous, following a long follow-up, has never been considered extensively. PATIENTS AND METHODS: We analyzed the Surveillance, Epidemiology, and End Results (SEER) database from 1973 to 2011 to follow-up all the cases of malignant struma ovarii in an effort of calculate the occurrence of SPTs in this cohort of patients...
September 2016: In Vivo
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