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https://www.readbyqxmd.com/read/28344950/impalement-head-injury-with-a-spear
#1
B I Akhiwu, A S Adoga, O P Binitie, C C Ani, M Iweagwu, O Adetutu, T Ureme, D D George, P D Didamson, E Oseni-Momodu, B T Ugwu
Impalement injuries to the craniofacial region are uncommon due to the fact that the face is a smaller target in relation to the rest of the body. We report a case of a 26-year old man who was attacked on the face with a spear. He was promptly evaluated and resuscitated; the blade of the spear was successfully extracted under general anaesthesia. He was discharged home after 2 weeks hospitalization; he has been followed up for three months with good outcome.
April 2016: Journal of the West African College of Surgeons
https://www.readbyqxmd.com/read/28341344/propofol-affinity-to-mitochondrial-membranes-does-not-alter-mitochondrial-function
#2
Luís M Félix, Fernando Correia, Pedro A Pinto, Sónia P Campos, Telma Fernandes, Romeu Videira, M M Oliveira, Francisco P Peixoto, Luís M Antunes
The molecular mechanisms of hepatotoxicity after propofol anaesthesia have not been fully elucidated, although there is a relation with mitochondrial dysfunction. The action of propofol on mitochondrial hepatic functions in a rat model was evaluated by infusion for 4h with 25 and 62.5mg/kg/h propofol or 3.125ml/kg/h (vehicle). Liver mitochondrial respiratory rates were evaluated as well as mitochondrial transmembrane potential (ΔΨ), calcium fluxes, mitochondrial enzymatic activities (Complex I-V) and oxidative stress biomarkers (superoxide dismutase, catalase, glutathione reductase, glutathione S-transferase, lipid peroxidation and the oxidised/reduced glutathione ratio)...
March 22, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28298758/comparison-of-analgesic-efficacy-of-dexmedetomidine-and-midazolam-as-adjuncts-to-lignocaine-for-intravenous-regional-anesthesia
#3
Bharti Gupta, Ravinder Kumar Verma, Sudershan Kumar, Geeta Chaudhary
BACKGROUND: Intravenous regional anesthesia (IVRA) is safe, technically simple, and cost-effective technique compared to general anesthesia with success rates of 94-98% for upper and lower limb surgeries. The main disadvantage of this procedure is its limited duration for surgery, lack of postoperative analgesia, and tourniquet pain. To overcome this disadvantage, various adjuvants to lignocaine have been studied from time to time. AIM: To compare the analgesic efficacy of dexmedetomidine and midazolam as adjuncts to lignocaine for IVRA for forearm and hand surgeries...
January 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28292564/commentary-on-regional-versus-local-anaesthesia-for-haemodialysis-arteriovenous-fistula-formation-a-systematic-review-and-meta-analysis
#4
J H M Tordoir
No abstract text is available yet for this article.
March 11, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28285956/regional-versus-local-anaesthesia-for-haemodialysis-arteriovenous-fistula-formation-a-systematic-review-and-meta-analysis
#5
REVIEW
R Cerneviciute, S M Sahebally, K Ahmed, M Murphy, W Mahmood, S R Walsh
BACKGROUND: Arteriovenous fistula (AVF) formation is the most common vascular access procedure for patients requiring haemodialysis. However, it is associated with high failure rates, influenced by vessel diameter and arterial inflow. Mode of anaesthesia may affect these factors, and subsequently AVF maturation rates. OBJECTIVE: To perform a systematic review and meta-analysis to assess the effect of anaesthesia type for autologous primary radiocephalic or brachiocephalic AVF creation on subsequent fistula failure rates...
March 10, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28251606/a-randomised-trial-of-peri-operative-positive-airway-pressure-for-postoperative-delirium-in-patients-at-risk-for-obstructive-sleep-apnoea-after-regional-anaesthesia-with-sedation-or-general-anaesthesia-for-joint-arthroplasty
#6
J W Nadler, J L Evans, E Fang, X A Preud'Homme, R L Daughtry, J B Chapman, M P Bolognesi, D E Attarian, S S Wellman, A D Krystal
Previous pilot work has established an association between obstructive sleep apnoea and the development of acute postoperative delirium , but it remains unclear to what extent this risk factor is modifiable in the 'real world' peri-operative setting. In a single-blind randomised controlled trial, 135 elderly surgical patients at risk for obstructive sleep apnoea were randomly assigned to receive peri-operative continuous positive airway pressure (CPAP) or routine care. Of the 114 patients who completed the study, 21 (18...
March 2, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28250487/anaesthetic-management-of-a-patient-with-severe-pulmonary-arterial-hypertension-for-renal-transplantation
#7
Mn Chidananda Swamy, Aninditha Mukherjee, Latha L Rao, Sushmitha Pandith
We describe a patient with severe pulmonary arterial hypertension scheduled to undergo live-related renal transplantation. We emphasise on meticulous anaesthetic management and early renal transplantation to prevent the progression of disease which would become refractory to treatment, leading to right ventricular failure. Regional (continuous epidural) anaesthesia has been used as technique of choice, where the selective advantages of this technique have been put to good use.
February 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28237681/assessment-of-distribution-of-ventilation-and-regional-lung-compliance-by-electrical-impedance-tomography-in-anaesthetized-horses-undergoing-alveolar-recruitment-manoeuvres
#8
Tamas D Ambrisko, Johannes Schramel, Klaus Hopster, Sabine Kästner, Yves Moens
OBJECTIVE: To examine changes in the distribution of ventilation and regional lung compliances in anaesthetized horses during the alveolar recruitment manoeuvre (ARM). STUDY DESIGN: Experimental study in which a series of treatments were administered in a fixed order on one occasion. ANIMALS: Five adult Warmblood horses. METHODS: Animals were anaesthetized (xylazine, midazolam-ketamine, isoflurane), placed in dorsal recumbency and ventilated with 100% oxygen using peak inspiratory pressure (PIP) and positive end-expiratory pressure (PEEP) of 20 cmH2O and 0 cmH2O, respectively...
January 12, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28236348/fixed-time-interval-compared-with-on-demand-oral-analgesia-protocols-for-post-caesarean-pain-a-randomised-controlled-trial
#9
E Yefet, H Taha, R Salim, J Hasanein, Y Carmeli, N Schwartz, Z Nachum
OBJECTIVES: To compare the efficacy, safety and satisfaction from two modes of oral analgesia administration for the treatment of post-caesarean pain in the first 48 h following surgery: on-demand versus fixed time interval administration. DESIGN: Open label parallel-group, randomised-controlled trial from February to December 2013. SETTING: University-affiliated hospital in Israel. POPULATION: Two-hundred women who underwent caesarean delivery with regional anaesthesia...
February 25, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28222642/prediction-of-intraoperative-nausea-and-vomiting-in-caesarean-delivery-under-regional-anaesthesia
#10
Altuğ Semiz, Yaşam Kemal Akpak, Necip Cihangir Yılanlıoğlu, Ali Babacan, Gökhan Gönen, Canan Çam Gönen, Murat Asıliskender, Selim Karaküçük
Objectives This study aimed to predict patients who have caesarean operations under regional anaesthesia and are at risk for intraoperative nausea and vomiting (IONV), for ultimately prompting anaesthetists and surgeons to take preventive measures. Methods This was a retrospective study on 209 patients who had caesarean section under spinal-epidural combined regional anaesthesia. The relevant medical history, such as severe nausea and vomiting in the first trimester, smoking, a history of motion sickness, and premenstrual syndrome (PMS), were obtained from the patients' records and interviews...
February 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28219323/a-preliminary-assessment-of-the-lma-protector%C3%A2-in-non-paralysed-patients
#11
Ban Leong Sng, Farida Binte Ithnin, Deepak Mathur, Eileen Lew, Nian-Lin Reena Han, Alex Tiong-Heng Sia
BACKGROUND: The LMA Protector™ is the latest CE marked single use supraglottic airway device. This airway device provides access and functional separation of the respiratory and digestive tracts. There are two ports (male, female ports) to provide suction in the laryngeal region and insertion of the gastric tube. The aim of our study is to assess the ease of use, airway quality, device positioning, airway leak and complications associated with initial clinical experience in LMA Protector™ usage...
February 20, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28208978/a-randomized-controlled-study-of-0-5-bupivacaine-0-5-ropivacaine-and-0-75-ropivacaine-for-supraclavicular-brachial-plexus-block
#12
Ranjan R Venkatesh, Prabhat Kumar, Ramachandran R Trissur, Sagiev Koshy George
INTRODUCTION: For any surgery in the upper extremity that does not involve the shoulder, a supraclavicular block is preferred, as it is a safe procedure associated with rapid onset and reliable anaesthesia. Although ropivacaine has been extensively studied for epidural anaesthesia, very few reports exist on its use in supraclavicular brachial plexus block. AIM: This study was conducted to investigate and compare the effectiveness of supraclavicular brachial plexus anaesthesia with two different concentrations of ropivacaine (0...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28185262/ultrasound-guided-approach-to-nerves-direct-vs-tangential-and-the-incidence-of-intraneural-injection-a-cadaveric-study
#13
L A Sermeus, X Sala-Blanch, J G McDonnell, C A Lobo, B J Nicholls, G J van Geffen, O Choquet, G Iohom, B de Jose Maria Galve, C Hermans, M Lammens
This study evaluated the incidence of nerve puncture and intraneural injection based on the needle approach to the nerve (direct vs. tangential). Two expert operators in regional anaesthesia performed in-plane ultrasound-guided nerve blocks (n = 158) at different levels of the brachial plexus in cadavers, aiming either directly for the nerve (n = 77) or tangentially inferior to the nerve (n = 81). After reaching the outer limit of the nerve, the needle was intentionally advanced approximately 1 mm in both approaches, and 0...
April 2017: Anaesthesia
https://www.readbyqxmd.com/read/28185241/safe-performance-of-peripheral-regional-anaesthesia-the-significance-of-ultrasound-guidance
#14
EDITORIAL
P Marhofer, G Fritsch
No abstract text is available yet for this article.
April 2017: Anaesthesia
https://www.readbyqxmd.com/read/28177164/midbrain-dopaminergic-neuron-activity-across-alternating-brain-states-of-urethane-anaesthetised-rat
#15
Magdalena Walczak, Tomasz Błasiak
Midbrain dopaminergic neurons are implicated in the control of motor functions and reward-driven behaviours. The function of this neuronal population is strongly connected with distinct patterns of firing - irregular or bursting, which either maintains basal levels of dopamine or leads to phasic release, respectively. Heterogeneity of dopaminergic neurons, observed on both structural and functional levels, is also reflected in different responses of DA neurons to changes in global brain states. Preparation of urethane anaesthetised animal is a broadly used model to study brain state dependent activity of neurons...
February 8, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28162785/efficacy-of-ultrasound-guided-transversus-abdominis-plane-block-in-laparoscopic-hysterectomy-clinical-trial
#16
D S Guardabassi, S Lupi, R Agejas, J M Allub, G García-Fornari
OBJECTIVES: Transversus abdominis plane block is a regional anaesthesia technique that has proven to be effective for postoperative pain reduction in different abdominal surgical procedures. This study evaluated its efficacy on post laparoscopic hysterectomy pain intensity and analgesic consumption. MATERIALS AND METHODS: Randomized controlled trial which included 40 patients scheduled for laparoscopic hysterectomy, enrolled in 2 groups: transversus abdominis plane block+systemic analgesia (Group 1; n=20), versus systemic analgesia (Group 2; n=20)...
February 2, 2017: Revista Española de Anestesiología y Reanimación
https://www.readbyqxmd.com/read/28159688/altered-regional-connectivity-reflecting-effects-of-different-anaesthesia-protocols-in-the-mouse-brain
#17
Tong Wu, Joanes Grandjean, Simone C Bosshard, Markus Rudin, David Reutens, Tianzi Jiang
Studies in mice using resting-state functional magnetic resonance imaging (rs-fMRI) have provided opportunities to investigate the effects of pharmacological manipulations on brain function and map the phenotypes of mouse models of human brain disorders. Mouse rs-fMRI is typically performed under anaesthesia, which induces both regional suppression of brain activity and disruption of large-scale neural networks. Previous comparative studies using rodents investigating various drug effects on long-distance functional connectivity (FC) have reported agent-specific FC patterns, however, effects of regional suppression are sparsely explored...
February 1, 2017: NeuroImage
https://www.readbyqxmd.com/read/28153548/neonatal-and-maternal-outcomes-of-pregnancy-with-maternal-cardiac-disease-the-normandy-study-%C3%A2-years-2000-2014
#18
Vincent Bonnet, Thérèse Simonet, Fabien Labombarda, Patricia Dolley, Paul Milliez, Michel Dreyfus, Jean-Luc Hanouz
Pregnancies complicated by congenital or acquired heart diseases are at high risk of maternal, obstetrical and neonatal poor outcomes. During the period 2000-2014, 197 pregnancies occurring in 147 women with heart disease were managed in our institution. A maternal cardiac event complicated 13 pregnancies. Obstetrical and neonatal complications occurred respectively in 35.0% (95% CI [28.3-41.7]) and 37.0% (95% CI [30.3-43.7]) of pregnancies. All complications were more frequent amongst cardiomyopathies or obstructive and conotruncal lesions, whereas left-to-right shunts were less prone to present with complications...
January 30, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/28134017/patient-controlled-regional-anaesthesia-for-severe-hand-pain-a-case-series
#19
S M W Pool, R J M Ter Braak
No abstract text is available yet for this article.
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28133720/heart-rate-variability-as-a-predictor-of-hypotension-following-spinal-for-elective-caesarean-section-a-prospective-observational-study
#20
D G Bishop, C Cairns, M Grobbelaar, R N Rodseth
Post-spinal hypotension remains a common and clinically-important problem during caesarean section, and accurate pre-operative prediction of this complication might enhance clinical management. We conducted a prospective, single-centre, observational study of heart rate variability in 102 patients undergoing elective caesarean section in a South African regional hospital. We performed Holter recording for ≥ 5 min in the hour preceding spinal anaesthesia. The low-frequency/high-frequency ratio component of heart rate variability was compared, using a logistic regression model, with baseline heart rate and body mass index (BMI) as a predictor of hypotension (defined as systolic arterial pressure < 90 mmHg) occurring from the time of spinal insertion until 15 min after delivery of the baby...
January 30, 2017: Anaesthesia
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