Eldad Saragosti, Aviva Fattal-Valevski, Dror Levin, Moran Hausman-Kedem, Shlomi Constantini, Noa Mecica, Shiri Zarour, Jonathan Roth
PURPOSE: Noonan syndrome (NS) is a rare neurodevelopmental syndrome characterized by dysmorphic features, congenital heart defects, neurodevelopmental delay, and bleeding diathesis. Though rare, several neurosurgical manifestations have been associated with NS, such as Chiari malformation (CM-I), syringomyelia, brain tumors, moyamoya, and craniosynostosis. We describe our experience in treating children with NS and various neurosurgical conditions, and review the current literature on neurosurgical aspects of NS...
February 27, 2023: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery