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https://www.readbyqxmd.com/read/28228892/metastatic-extrapleural-malignant-solitary-fibrous-tumor-presenting-with-hypoglycemia-doege-potter-syndrome
#1
Andrew J Degnan, Kenneth K W Lee, Marta I Minervini, Amir A Borhani
We report a rare case of metastatic malignant solitary fibrous tumor (SFT) that presented with hypoglycemia because of insulin growth factor-2 production. Initial workup included computed tomography imaging that revealed a large, partially necrotic liver mass, a hypervascular pancreatic head lesion, and 2 renal lesions. Following hepatic resection, pancreatic head resection and nephrectomy, all these lesions demonstrated pathological findings that were consistent with SFT. The patient also had a history of an intracranial mass that had been previously resected and treated with gamma knife therapy at an outside institution, which was found to also be SFT...
March 2017: Radiology case reports
https://www.readbyqxmd.com/read/28220368/embolization-of-ruptured-arteriovenous-malformations-in-the-cerebellopontine-angle-cistern
#2
Hidenori Endo, Shin-Ichiro Osawa, Yasushi Matsumoto, Toshiki Endo, Kenichi Sato, Kuniyasu Niizuma, Miki Fujimura, Teiji Tominaga
Among brainstem arteriovenous malformations (AVMs), there exist small AVMs predominantly located in the cerebellopontine angle cistern (CPAC) with minimal extension into the pial surface of the brainstem. However, previous studies of CPAC AVMs did not particularly discuss the role of embolization in the treatment of these lesions. This study was conducted to clarify the effectiveness and validity of embolization in the treatment of CPAC AVMs. We retrospectively reviewed five patients with CPAC AVMs who underwent endovascular treatment...
February 20, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28217873/radiosurgery-for-arteriovenous-malformations-and-the-impact-on-headaches
#3
Greg Bowden, Jonathon Cavaleri, Hideyuki Kano, Edward Monaco, Ajay Niranjan, John Flickinger, L Dade Lunsford
BACKGROUND: Arteriovenous malformations (AVMs) can underlie many diverse neurological signs and symptoms. Headaches are a common presentation that can have a significant impact on quality of life. OBJECTIVE: The authors investigated Gamma Knife(®) stereotactic radiosurgery (SRS) outcomes in patients with AVMs and associated headaches. METHODS: This retrospective study analyzed 102 patients with AVMs who underwent SRS between 1995 and 2013...
February 20, 2017: Headache
https://www.readbyqxmd.com/read/28216397/gamma-knife-radiosurgery-for-low-grade-gliomas-clinical-results-at-long-term-follow-up-on-tumor-control-and-patients-quality-of-life
#4
Filippo Gagliardi, Michele Bailo, Alfio Spina, Carmine A Donofrio, Nicola Boari, Alberto Franzin, Arianna Fava, Antonella Del Vecchio, Angelo Bolognesi, Pietro Mortini
OBJECT: Surgery represents first-line therapy for low-grade gliomas (LGGs), in some cases followed by radiotherapy (RT) and chemotherapy. Gamma Knife radiosurgery (GKRS) has gained more relevance in the management of these tumors. The aim of the study was to assess the efficacy and safety of GKRS for the treatment of LGGs. METHODS: Forty-two treatments, performed between 2001 and 2014 on 39 patients harboring LGGs, were included. Forty-eight percent of patients underwent previous surgery, while 20...
February 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28191290/loss-of-efficacy-of-pasireotide-after-its-re-administration-is-there-a-reason-why
#5
Stylianos Mandanas, Lemonia Mathiopoulou, Maria Boudina, Alexandra Chrisoulidou, Kalliopi Pazaitou-Panayiotou
Pasireotide is a recently approved medical treatment for persistent or recurrent Cushing's disease (CD). However, an escape from the initial successful response has not yet been described. A 42-year-old female presented with several symptoms indicative of hypercortisolism. Biochemical evaluation and imaging were consistent with CD due to a pituitary adenoma. Surgical excision of the adenoma was unsuccessful and gamma-knife radiosurgery was followed. Our patient remained hypercortisolemic thus treatment with pasireotide (900 mg subcutaneously twice daily) was decided...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/28186452/magnetic-resonance-imaging-characteristics-and-the-prediction-of-outcome-of-vestibular-schwannomas-following-gamma-knife-radiosurgery
#6
Chih-Chun Wu, Wan-Yuo Guo, Wen-Yuh Chung, Hisu-Mei Wu, Chung-Jung Lin, Cheng-Chia Lee, Kang-Du Liu, Huai-Che Yang
OBJECTIVE Gamma Knife surgery (GKS) is a promising treatment modality for patients with vestibular schwannomas (VSs), but a small percentage of patients have persistent postradiosurgical tumor growth. The aim of this study was to determine the clinical and quantitative MRI features of VS as predictors of long-term tumor control after GKS. METHODS The authors performed a retrospective study of all patients with VS treated with GKS using the Leksell Gamma Knife Unit between 2005 and 2013 at their institution...
February 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28186449/efficacy-and-outcomes-of-facial-nerve-sparing-treatment-approach-to-cerebellopontine-angle-meningiomas
#7
Randy S D'Amico, Matei A Banu, Petros Petridis, Alexandra S Bercow, Hani Malone, Moshe Praver, Tony J C Wang, Steven R Isaacson, Michael B Sisti
OBJECTIVE Advanced microsurgical techniques contribute to reduced morbidity and improved surgical management of meningiomas arising within the cerebellopontine angle (CPA). However, the goal of surgery has evolved to preserve the quality of the patient's life, even if it means leaving residual tumor. Concurrently, Gamma Knife radiosurgery (GKRS) has become an acceptable and effective treatment modality for newly diagnosed, recurrent, or progressive meningiomas of the CPA. The authors review their institutional experience with CPA meningiomas treated with GKRS, surgery, or a combination of surgery and GKRS...
February 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28185974/direct-comparison-of-gamma-knife-radiosurgery-and-microsurgery-for-small-size-meningiomas
#8
Shyamal C Bir, Devi Prasad Patra, Tanmoy Kumar Maiti, Papireddy Bollam, Alireza Minagar, Anil Nanda
INTRODUCTION: A patient with a small (<3cm) intracranial meningioma can be either observed or treated. Treatment can be either radiosurgery or microsurgery if and when progression of the tumor occurs. We have compared the local tumor growth control and recurrence-free survival (RFS) of microsurgical resection and radiosurgery in small intracranial meningiomas, and we have identified the predictors of unfavorable outcome. MATERIALS AND METHODS: Retrospective review (2005-2016) of 90 consecutive patients with intracranial meningiomas who underwent either microsurgery (n=31) or gamma knife radiosurgery (GKRS, n=59) was done...
February 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28183144/rapid-deterioration-of-latent-hbv-hepatitis-during-cushing-disease-and-posttraumatic-stress-disorder-after-earthquake
#9
Ryosuke Tashiro, Yoshikazu Ogawa, Teiji Tominaga
Reactivation of the hepatitis B virus (HBV) is a risk in the 350 million HBV carriers worldwide. HBV reactivation may cause hepatocellular carcinoma, cirrhosis, and fulminant hepatitis, and HBV reactivation accompanied with malignant tumor and/or chemotherapy is a critical problem for patients with chronic HBV infection. Multiple risk factors causing an immunosuppressive state can also induce HBV reactivation.We present a case of HBV reactivation during an immunosuppressive state caused by Cushing disease and physical and psychological stress after a disaster...
February 9, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28180036/low-dose-gamma-knife-radiosurgery-for-vestibular-schwannomas-tumor-control-and-cranial-nerve-function-preservation-after-11-gy
#10
Andrew J Schumacher, Rohan R Lall, Rishi R Lall, Allan Nanney Iii, Amit Ayer, Samir Sejpal, Benjamin P Liu, Maryanne Marymont, Plato Lee, Bernard R Bendok, John A Kalapurakal, James P Chandler
Objectives This study aims to report tumor control rates and cranial nerve function after low dose (11.0 Gy) Gamma knife radiosurgery (GKRS) in patients with vestibular schwannomas. Methods A retrospective chart review was performed on 30 consecutive patients with vestibular schwannomas treated from March 2004 to August 2010 with GKRS at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. The marginal dose for all patients was 11.0 Gy prescribed to the 50% isodose line. Median follow-up time was 42 months...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28175507/357%C3%A2-gamma-knife-stereotactic-radiosurgery-in-the-management-of-large-cerebral-arteriovenous-malformations
#11
Manmohan Singh, Deepak Aggarwal, Shashank Sharad Kale
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28175479/204%C3%A2-pediatrics-arteriovenous-malformations-treatment-with-stereotactic-radiosurgery-gamma-knife-our-institutional-experience
#12
Jody Filippo Capitanio, Alberto Luigi Gallotti, Pietro Panni, Silvia Snider, Francesco Scomazzoni, Pietro Mortini
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28173447/emerging-indications-for-fractionated-gamma-knife-radiosurgery
#13
Emory McTyre, Corbin A Helis, Michael Farris, Lisa Wilkins, Darrell Sloan, William H Hinson, J Daniel Bourland, William A Dezarn, Michael T Munley, Kounosuke Watabe, Fei Xing, Adrian W Laxton, Stephen B Tatter, Michael D Chan
No abstract text is available yet for this article.
February 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28169200/corrigendum-to-microsurgical-resection-for-persistent-arteriovenous-malformations-following-gamma-knife-radiosurgery-a-case-control-study-world-neurosurg-88-2016-277-288
#14
Xianzeng Tong, Jun Wu, Jian Pan, Fuxin Lin, Yong Cao, Yuanli Zhao, Shuo Wang, Jizong Zhao
No abstract text is available yet for this article.
February 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28168125/role-of-gamma-knife%C3%A2-radiosurgery-for-the-treatment-of-brain-metastases-from-gynecological-cancers
#15
Andrew Keller, Rahim Ismail, Peter S Potrebko, Julie Pepe, Meiling Wu, Kunal Saigal, Matthew Biagioli, Ravi Shridhar, Robert Holloway, Melvin Field, Nikhil G Rao
OBJECTIVE: Gamma Knife(®) (GK) (Elekta Instruments, Stockholm, Sweden) radiosurgery is well established for treatment of brain metastases. There are limited data on patients treated with GK from gynecological cancers. The authors sought to determine the effectiveness of the GK in patients with brain metastases from gynecological cancers. METHODS: An IRB-approved database was queried for patients with gynecologic cancers treated with GK between June 1996 and May 2016...
December 31, 2016: Curēus
https://www.readbyqxmd.com/read/28163514/pilocytic-midbrain-astrocytoma-presenting-with-fresh-bleed-after-twenty-one-years-survival-following-first-surgery-a-unique-case-of-longest-brainstem-glioma-survival
#16
Guru Dutta Satyarthee, M D Sudhan, V S Mehta
Brainstem glioma usually carries a poor prognosis and prolonged survival is very infrequent. In a detailed Pubmed, Medline search for prolonged survival, authors could got a longest survival only up to seventeen years, reported by Umehara et al, who was subjected to gamma knife therapy and got symptomatic, MRI brain reveled large tumor growth during pregnancy necessitating emergency surgery and histopathological diagnosis was pilocytic astrocytoma. Authors report an interesting case of midbrain glioma diagnosed 21 years back, who underwent gross resection in the year 1993, histopathology was pilocytic astrocytoma, WHO grade I, and received gamma knife surgery for residual subsequently and he presented with sudden onset left sided hemiplegia on the current admission...
December 2016: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28161431/dosimetric-and-radiobiologic-comparison-of-103-pd-coms-plaque-brachytherapy-and-gamma-knife-radiosurgery-for-choroidal-melanoma
#17
Daniel Gorovets, Nolan L Gagne, Christopher S Melhus
PURPOSE: Plaque brachytherapy (BT) and Gamma Knife radiosurgery (GKRS) are highly conformal treatment options for choroidal melanoma. This study objectively compares physical dose and biologically effective dose (BED) distributions for these two modalities. METHODS AND MATERIALS: Tumor and organ-at-risk (OAR) dose distributions from a CT-defined reference right eye were compared between (103)Pd COMS (Collaborative Ocular Melanoma Study Group) plaques delivering 70 Gy (plaque heterogeneity corrected) over 120 h to the tumor apex and GKRS plans delivering 22 Gy to the 40% isodose line for a representative sample of clinically relevant choroidal melanoma locations and sizes...
February 1, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28156245/multimodal-treatment-of-parasagittal-meningiomas-a-single-center-experience
#18
Brigitte Gatterbauer, Sinan Gevsek, Romana Höftberger, Carola Lütgendorf-Caucig, Adolf Ertl, Ammar Mallouhi, Klaus Kitz, Engelbert Knosp, Josa M Frischer
OBJECTIVE Treatment of parasagittal meningiomas is still considered a challenge in modern microsurgery. The use of microsurgical resection, radiosurgery, or a microsurgery-radiosurgery combination treatment strategy is often debated. The aim of this study was to evaluate the treatment of parasagittal meningioma and provide evidence that a multimodal approach reduces complication rates and achieves good tumor control rates. METHODS The authors retrospectively reviewed long-term follow-up data on 117 patients who had been treated for parasagittal meningiomas at their institution between 1993 and 2013...
February 3, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28139076/gamma-knife-radiosurgery-for-brain-metastases-from-gastrointestinal-primary
#19
Brandi R Page, Edina C Wang, Lance White, Emory McTyre, Ann Peiffer, Angela Alistar, Frank Mu, Amritraj Loganathan, John Daniel Bourland, Adrian W Laxton, Stephen B Tatter, Michael D Chan
INTRODUCTION: In this study, we assessed clinical outcomes of patients with brain metastases from a gastrointestinal (GI) primary cancer and patterns of failure after stereotactic radiosurgery including failure within the radiosurgical volume, distant failure and leptomeningeal failure (LMF). We also assessed other factors associated with the patients' neurologic and extraneuraxial disease that may affect clinical outcomes. METHODS: We reviewed our institutional series of 62 consecutive patients with brain metastases treated with stereotactic radiosurgery, which included 17 patients with oesophageal, 44 patients with colorectal and one patient with anal canal primary...
January 31, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28135704/implementation-of-a-new-upmc-gamma-knife-radiosurgery-quality-assurance-registry
#20
Ajay Niranjan, Denise Layne, Mark Briercheck, Svetlana Trofimova, Edward A Monaco Iii, Hideyuki Kano, L Dade Lunsford
OBJECT: In this report, we discuss the development of a new, comprehensive, Health Insurance Portability and Accountability Act-compliant electronic quality assurance (QA) registry for Gamma Knife (GK) radiosurgery patients. This registry can be used to query outcomes, link with current hospital electronic medical records, and share data with future corporate or national professional society registries under development. METHODS: A clinical task force comprising physicians and regulatory, legal, and information technology (IT) experts was created to define the nomenclature, regulatory requirements, hosting site, and required capabilities of the proposed system...
January 28, 2017: Stereotactic and Functional Neurosurgery
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