keyword
MENU ▼
Read by QxMD icon Read
search

Gamma knife

keyword
https://www.readbyqxmd.com/read/29161788/aggressive-supratentorial-ependymoma-rela-fusion-positive-with-extracranial-metastasis-a-case-report
#1
Seong-Ik Kim, Yoojin Lee, Seung Ki Kim, Hyoung Jin Kang, Sung-Hye Park
Ependymoma is the third most common pediatric primary brain tumor. Ependymomas are categorized according to their locations and genetic abnormalities, and these two parameters are important prognostic factors for patient outcome. For supratentorial (ST) ependymomas, RELA fusion-positive ependymomas show a more aggressive behavior than YAP1 fusion-positive ependymomas. Extracranial metastases of intra-axial neuroepithelial tumors are extremely rare. In this paper, we report a case of aggressive anaplastic ependymoma arising in the right frontoparietal lobe, which had genetically 1q25 gain, CDKN2A homozygous deletion, and L1CAM overexpression...
November 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29155347/postoperative-gamma-knife-radiosurgery-for-cavernous-sinus-invading-growth-hormone-secreting-pituitary-adenomas
#2
Eui Hyun Kim, Min Chul Oh, Jong Hee Chang, Ju Hyung Moon, Cheol Ryong Ku, Won-Seok Chang, Eun Jig Lee, Sun Ho Kim
OBJECTIVE: We aimed to determine the long-term effects of Gamma knife radiosurgery (GKS) on remnants in the cavernous sinus (CS) after transsphenoidal surgery (TSS) for acromegaly and to identify its possible adverse effects. METHODS: Thirty patients who had remnant tumors only inside the CS after TSS and who consequently underwent GKS were included. They were followed for a median period of 47 months after GKS with regular hormonal and radiological examinations...
November 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29131131/gamma-knife-stereotactic-radiosurgery-for-the-treatment-of-primary-and-metastatic-ocular-malignancies
#3
Andrea L H Arnett, Margaret M Reynolds, Jose S Pulido, Ian F Parney, Nadia N Laack
BACKGROUND: Gamma knife radiosurgery (GKR) can be used for precise targeting of malignant lesions of the CNS when brachytherapy is not an appropriate option. OBJECTIVES: This study reports treatment technique, efficacy, and radiation-induced adverse effects in patients with primary and metastatic ocular lesions treated with Leksell GKR. METHODS: A retrospective, single-institution review was conducted of 28 patients with primary or metastatic ocular disease, treated from 2000 to 2014...
November 4, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/29131117/significant-hemorrhage-rate-reduction-after-gamma-knife-radiosurgery-in-symptomatic-cavernous-malformations-long-term-outcome-in-95-case-series-and-literature-review
#4
Remedios López-Serrano, Nuria E Martínez, M Elena Kusak, Alicia Quirós, Roberto Martínez
BACKGROUND: The natural history of cavernous malformations (CMs) has remained unclear. This lack of knowledge has made treatment decisions difficult. Indeed, the use of stereotactic radiosurgery is nowadays controversial. The purpose of this paper is to throw light on the effectiveness of Gamma Knife radiosurgery (GKRS) therapy. METHODS: The authors reviewed data collected from a prospectively maintained database. A total of 95 patients (57 female and 38 male) underwent GKRS for high-surgical-risk CMs...
November 4, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/29125412/stereotactic-radiosurgery-for-jugular-foramen-schwannomas-an-international-multicenter-study
#5
Hideyuki Kano, Antonio Meola, Huai-Che Yang, Wan-Yuo Guo, Roberto Martínez-Alvarez, Nuria Martínez-Moreno, Dusan Urgosik, Roman Liscak, Or Cohen-Inbar, Jason Sheehan, John Y K Lee, Mahmoud Abbassy, Gene H Barnett, David Mathieu, Douglas Kondziolka, L Dade Lunsford
OBJECTIVE For some jugular foramen schwannomas (JFSs), complete resection is possible but may be associated with significant morbidity. Stereotactic radiosurgery (SRS) is a minimally invasive alternative or adjunct to microsurgery for JFSs. The authors reviewed clinical and imaging outcomes of SRS for patients with these tumors. METHODS Nine participating centers of the International Gamma Knife Research Foundation identified 92 patients who underwent SRS between 1990 and 2013. Forty-one patients had prior subtotal microsurgical resection...
November 10, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29114270/trigeminal-neuralgia
#6
REVIEW
Yad Ram Yadav, Yadav Nishtha, Pande Sonjjay, Parihar Vijay, Ratre Shailendra, Khare Yatin
Trigeminal neuralgia (TN) is a sudden, severe, brief, stabbing, and recurrent pain within one or more branches of the trigeminal nerve. Type 1 as intermittent and Type 2 as constant pain represent distinct clinical, pathological, and prognostic entities. Although multiple mechanism involving peripheral pathologies at root (compression or traction), and dysfunctions of brain stem, basal ganglion, and cortical pain modulatory mechanisms could have role, neurovascular conflict is the most accepted theory. Diagnosis is essentially clinically; magnetic resonance imaging is useful to rule out secondary causes, detect pathological changes in affected root and neurovascular compression (NVC)...
October 2017: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29102948/five-year-survival-after-surgical-removal-and-gamma-knife-stereotactic-radiosurgery-for-a-cerebellar-metastasis-from-an-esophagogastric-junction-cancer-a-case-report-and-literature-review
#7
Yoshikazu Kanazawa, Itsuo Fujita, Daisuke Kakinuma, Yuto Aoki, Hitoshi Kanno, Hiroki Arai, Kunihiko Matsuno, Tomohiro Shimoda, Takeshi Matsutani, Nobutoshi Hagiwara, Tsutomu Nomura, Takeshi Yamada, Shunji Kato, Zenya Naito, Hideaki Takasaki, Eiji Uchida
Brain metastases originating from esophageal or gastric cancer are rare, accounting for 2.1-3.3% of all brain tumors registered in Japan. There are no established therapeutic measures for brain metastases, which accordingly have a poor prognosis. We present here a patient who survived for 5 years after surgery and gamma knife treatment of a cerebellar metastasis from esophagogastric adenocarcinoma. The primary gastric cancer was treated by laparotomy with total gastrectomy, splenectomy, and D2 lymphadenectomy...
November 2017: In Vivo
https://www.readbyqxmd.com/read/29082599/failure-modes-and-effects-analysis-fmea-for-gamma-knife-radiosurgery
#8
Andy Yuanguang Xu, Jagdish Bhatnagar, Greg Bednarz, John Flickinger, Yoshio Arai, Jonet Vacsulka, Wenzheng Feng, Edward Monaco, Ajay Niranjan, L Dade Lunsford, M Saiful Huq
PURPOSE: Gamma Knife radiosurgery is a highly precise and accurate treatment technique for treating brain diseases with low risk of serious error that nevertheless could potentially be reduced. We applied the AAPM Task Group 100 recommended failure modes and effects analysis (FMEA) tool to develop a risk-based quality management program for Gamma Knife radiosurgery. METHODS: A team consisting of medical physicists, radiation oncologists, neurosurgeons, radiation safety officers, nurses, operating room technologists, and schedulers at our institution and an external physicist expert on Gamma Knife was formed for the FMEA study...
October 29, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29080088/gamma-knife-radiosurgery-for-basal-cell-carcinoma-of-the-eyelid-report-of-a-case
#9
Satoshi Suzuki, Shinsuke Yasukawa, Ryosuke Tsuchimochi, Takuya Inoue
Basal cell carcinoma (BCC) is the most common malignancy in the face. Surgical removal and reconstruction is the first choice of treatment options for BCC, but it tends to be invasive and sometimes is accompanied by a drastic change in appearance. We report here a case of BCC in the eyelid of a patient who was successfully treated by gamma knife radiosurgery (GKRS). He was 88 years old at this time. The ulcer disappeared within 3 weeks after GKRS and was covered with normal epithelium. This is the first report to describe an eyelid BCC that was treated by GKRS...
October 28, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29076785/early-versus-late-gamma-knife-radiosurgery-following-transsphenoidal-surgery-for-nonfunctioning-pituitary-macroadenomas-a-multicenter-matched-cohort-study
#10
I Jonathan Pomeraniec, Hideyuki Kano, Zhiyuan Xu, Brandon Nguyen, Zaid A Siddiqui, Danilo Silva, Mayur Sharma, Hesham Radwan, Jonathan A Cohen, Robert F Dallapiazza, Christian Iorio-Morin, Amparo Wolf, John A Jane, Inga S Grills, David Mathieu, Douglas Kondziolka, Cheng-Chia Lee, Chih-Chun Wu, Christopher P Cifarelli, Tomas Chytka, Gene H Barnett, L Dade Lunsford, Jason P Sheehan
OBJECTIVE Gamma Knife radiosurgery (GKRS) is frequently used to treat residual or recurrent nonfunctioning pituitary macroadenomas. There is no consensus as to whether GKRS should be used early after surgery or if radiosurgery should be withheld until there is evidence of imaging-defined progression of tumor. Given the high incidence of adenoma progression after subtotal resection over time, the present study intended to evaluate the effect of timing of radiosurgery on outcome. METHODS This is a multicenter retrospective review of patients with nonfunctioning pituitary macroadenomas who underwent transsphenoidal surgery followed by GKRS from 1987 to 2015 at 9 institutions affiliated with the International Gamma Knife Research Foundation...
October 27, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29074316/outcome-of-gamma-knife-radiosurgery-for-trigeminal-neuralgia-associated-with-neurovascular-compression
#11
Cheng-Siu Chang, Cheng-Wei Huang, His-Hsien Chou, Long-Yau Lin, Chuan-Fu Huang
We reviewed 130 patients from 1999 to 2012 to evaluate whether neurovascular compression (NVC) has prognostic value for pain relief in idiopathic trigeminal neuralgia (TN) treated by Gamma Knife radiosurgery (GKRS). Patients were assigned to one of the following groups based on NVC identified by MRI: no NVC, small vessel NVC, and large vessel (defined as part of the vertebrobasilar arterial system) NVC. Follow-up ranged from 4 to 14years. Primary outcome was pain graded by the Barrow Neurological Institute (BNI) pain scale...
October 23, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29069961/factors-affecting-hearing-deterioration-in-vestibular-schwannoma-patients-treated-with-gamma-knife-radiosurgery-the-asan-medical-center-experience
#12
Marn Joon Park, Hong Ju Park, Jong Woo Chung, Do Heui Lee, Young Hyun Cho, Young Jun Choi, Joong Ho Ahn
OBJECTIVES: To investigate the changes in hearing and to determine factors predicting hearing deterioration in patients with vestibular schwannoma (VS) who undergo gamma knife radiosurgery (GKRS). DESIGN: A retrospective review of medical records in patients diagnosed with VS and initially treated with GKRS at a tertiary care medical center between 1995 and 2015 was performed. Tumor factors (location, volume), parameters related to irradiation to the tumor and cochlea, and distance between the tumor and cochlea were reviewed...
October 25, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29040773/treatment-outcomes-of-a-randomized-trial-of-unruptured-brain-arteriovenous-malformation-eligible-unruptured-brain-arteriovenous-malformation-patients
#13
Min Lang, Nina Z Moore, Peter A Rasmussen, Mark D Bain
BACKGROUND: The guideline for treating unruptured brain arteriovenous malformations (ubAVMs) remains controversial. A Randomized Trial of Unruptured Brain Arteriovenous Malformations (ARUBA) reported lower risk of stroke or death with conservative management compared to interventional treatment. There were numerous limitations to the study, including short follow-up period and disproportionate number of patients treated with surgery and embolization. OBJECTIVE: To evaluate whether treatment of ARUBA-eligible patients have acceptable outcomes at our institution...
October 10, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29038085/outcomes-of-two-isocenter-gamma-knife-radiosurgery-for-typical-trigeminal-neuralgia-patients-pain-response-and-quality-of-life
#14
Zhao Hongyang, Shen Yin, Yao Dongxiao, Xiong Nanxiang, Ahmed Abdelmaksoud, Wang Haijun
OBJECTIVE: To evaluate the effectiveness and safety of two isocenter GKS by reviewing TN patients of last ten years. METHODS: A total of 247 patients were followed up and the Barrow Neurological Institute (BNI) scale was employed to evaluate pain degree. Patients' age, gender, pain duration and location, pre/post-operative BNI score, time to initial pain relief, recurrence time and complications were documented and analyzed. RESULTS: Patients who underwent a two isocenter GKS could get an earlier initial pain relief...
October 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29022157/radiosurgery-in-trochlear-and-abducens-nerve-schwannomas-case-series-and-systematic-review
#15
Iulia Peciu-Florianu, Constantin Tuleasca, Jean-Nicolas Comps, Luis Schiappacasse, Michele Zeverino, Roy Thomas Daniel, Marc Levivier
INTRODUCTION: Schwannomas involving the occulomotor cranial nerves  (CNs; III, IV and VI), can be disabling, due to the associated diplopia and decreased quality of life and are extremely rare. We evaluated the role of Gamma Knife surgery (GKS) in these cases. METHODS: Five patients with CN IV and VI schwannomas (three and two, respectively) were treated in Lausanne University Hospital between 2010 and 2015. Four benefitted from upfront GKS and one from a combined approach (planned subtotal resection followed by GKS), due to a large preoperative tumour volume (size, 3 × 2 × 2...
October 11, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29019347/pituitary-gland-gamma-knife-for-cushing-disease-time-for-a-reappraisal
#16
Frederic Castinetti, Thierry Brue
No abstract text is available yet for this article.
October 11, 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/29017157/impact-of-the-number-of-metastatic-tumors-treated-by-stereotactic-radiosurgery-on-the-dose-to-normal-brain-implications-for-brain-protection
#17
Charlotte Rivers, Marissa Tranquilli, Shefalika Prasad, Evan Winograd, Robert J Plunkett, Robert A Fenstermaker, Andrew J Fabiano, Matthew B Podgorsak, Dheerendra Prasad
PURPOSE/OBJECTIVES: The purpose of this study was to evaluate the effect of the number of brain lesions for which stereotactic radiosurgery (SRS) was performed on the dose volume relationships in normal brain. MATERIALS AND METHODS: Brain tissue was segmented using the patient's pre-SRS MRI. For each plan, the following data points were recorded: total brain volume, number of lesions treated, volume of brain receiving 8 Gy (V8), V10, V12, and V15. RESULTS: A total of 225 Gamma Knife® treatments were included in this retrospective analysis...
October 11, 2017: Stereotactic and Functional Neurosurgery
https://www.readbyqxmd.com/read/28992711/-treatment-of-pituitary-adenomas
#18
Jana Ježková, Josef Marek, Manuela Vaněčková
Pituitary adenomas are the most common tumours of the sellar region. A combination of neurosurgery, radiation and pharmacological approaches are applied for the treatment of pituitary adenomas. In certain cases, patient observation is another option. Neurosurgery is the first-choice treatment for acromegaly, Cushing´s disease and TSH secreting adenomas. Leksell gamma knife irradiation is used in the treatment of tumour residues. Until the effect of the irradiation is evident, pharmacological treatment must be administered...
2017: Casopís Lékar̆ů C̆eských
https://www.readbyqxmd.com/read/28987849/who-grade-ii-meningiomas-the-role-of-adjuvant-salvage-gamma-knife-surgery-after-initial-surgery-and-prognostic-factor-assessment
#19
Xueyou Liu, Baoyin Shan, Mengmeng Wang, Jianguo Xu
OBJECTIVE: This study was performed to evaluate the efficiency of gamma knife surgery (GKS) on reducing recurrence for World Health Organization (WHO) grade II meningiomas after surgery, and to define the risk factors associated with tumor recurrence/progression and patient's death. METHODS: This retrospective study included 75 patients who were diagnosed with WHO grade II meningiomas after initial surgery. Kaplan-Meier method with log-rank test was used to calculate the survival curves...
October 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28984523/retreatment-of-vestibular-schwannoma-with-gamma-knife-radiosurgery-clinical-outcome-tumor-control-and-review-of-literature
#20
Victor X Fu, Jeroen B Verheul, Guus N Beute, Sieger Leenstra, Henricus P M Kunst, Jef J S Mulder, Patrick E J Hanssens
OBJECTIVE Gamma Knife radiosurgery (GKRS) has become an accepted treatment for vestibular schwannoma, with a high rate of tumor control and good clinical outcome. In a small number of cases, additional treatment is needed. This retrospective study examines the clinical outcome, reproducibility of volumetric response patterns, and tumor control rate after administering a second GKRS to treat vestibular schwannomas. METHODS A total of 38 patients were included: 28 patients underwent a radiosurgical procedure as the initial treatment (Group 1), and 10 patients underwent microsurgical resection with adjuvant radiosurgery on the tumor remnant as the initial treatment (Group 2)...
October 6, 2017: Journal of Neurosurgery
keyword
keyword
11193
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"