S Hussaini, A Mamyraiym Kyzy, J Schröder-Schetelig, S L Lädke, V Venkatesan, L Diaz-Maue, R A Quiñonez Uribe, C Richter, V N Biktashev, R Majumder, V Krinski, S Luther
Malignant cardiac tachyarrhythmias are associated with complex spatiotemporal excitation of the heart. The termination of these life-threatening arrhythmias requires high-energy electrical shocks that have significant side effects, including tissue damage, excruciating pain, and worsening prognosis. This significant medical need has motivated the search for alternative approaches that mitigate the side effects, based on a comprehensive understanding of the nonlinear dynamics of the heart. Cardiac optogenetics enables the manipulation of cellular function using light, enhancing our understanding of nonlinear cardiac function and control...
March 1, 2024: Chaos