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https://www.readbyqxmd.com/read/29782278/-predictive-significance-of-disturbed-water-salt-homeostasis-in-decompensated-chronic-heart-failure-patients
#1
K S Fazulina, V V Fomin, V V Meshalkina
AIM: To estimate association between disorders of salt-water homeostasis on admision and the remote one-year prognosis for patients hospitalized with decompensated CHF NYHA FC III-IV. MATERIALS AND METHODS: This prospective study was based on clinical amnestic data and results of one-year follow-up of 111 consecutive patients admitted for decompensation of CHF to the State Clinical Hospital No. 24 in January 2015‑February 2016. RESULTS: The relative risk of death within one year for patients hospitalized for decompensated CHF with disorders of water and salt homeostasis increased 1...
2018: Kardiologiia
https://www.readbyqxmd.com/read/29780027/relationships-between-functional-fitness-and-cognitive-impairment-in-chinese-community-dwelling-older-adults-a-cross-sectional-study
#2
Mei Yang, Yan Guo, Jie Gong, Mengyao Deng, Niannian Yang, Yaqiong Yan
OBJECTIVE: The aim of this study was to investigate the associations between each functional fitness (FF) domain and cognitive impairment (CI) in Chinese community-dwelling older adults. DESIGN: A community-based, cross-sectional study was conducted. SETTING: Participants were selected by multistage stratified random sampling in Wuhan City, Hubei Province, Central China, during December 2015-May 2016. PARTICIPANTS: A total of 2096 (1031 male and 1065 female) adults older than 65 years were included in our study...
May 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29737474/incidence-and-risk-factors-for-congestive-heart-failure-in-patients-with-early-breast-cancer-who-received-anthracycline-and-or-trastuzumab-a-big-data-analysis-of-the-korean-health-insurance-review-and-assessment-service-database
#3
Jung Yoon Choi, Eun Young Cho, Yoon Ji Choi, Jeong Hyeon Lee, Seung Pil Jung, Kyu Ran Cho, Chul Yong Kim, Yeul Hong Kim, Kyong Hwa Park
PURPOSE: We aimed to analyze the incidence, time to occurrence, and congestive heart failure (CHF) risk factors for early breast cancer patients treated with anthracycline (AC)-based chemotherapy and/or trastuzumab (T) therapy in Korea. METHODS: We included female patients > 19 years old from the Health Insurance Review and Assessment Service database who had no prior CHF history and had been diagnosed with early breast cancer between January 2007 and October 2016...
May 8, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29699493/effects-of-age-comorbidity-and-adherence-to-current-antimicrobial-guidelines-on-mortality-in-hospitalized-elderly-patients-with-community-acquired-pneumonia
#4
Xiudi Han, Fei Zhou, Hui Li, Xiqian Xing, Liang Chen, Yimin Wang, Chunxiao Zhang, Xuedong Liu, Lijun Suo, Jinxiang Wang, Guohua Yu, Guangqiang Wang, Xuexin Yao, Hongxia Yu, Lei Wang, Meng Liu, Chunxue Xue, Bo Liu, Xiaoli Zhu, Yanli Li, Ying Xiao, Xiaojing Cui, Lijuan Li, Jay E Purdy, Bin Cao
BACKGROUND: Limited information exists on the clinical characteristics predictive of mortality in patients aged ≥65 years in many countries. The impact of adherence to current antimicrobial guidelines on the mortality of hospitalized elderly patients with community-acquired pneumonia (CAP) has never been assessed. METHODS: A total of 3131 patients aged ≥65 years were enrolled from a multi-center, retrospective, observational study initiated by the CAP-China network...
April 24, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29692618/an-evaluation-of-the-budget-impact-of-a-new-20-subcutaneous-immunoglobulin-ig20gly-for-the-management-of-primary-immunodeficiency-diseases-in-switzerland
#5
Richard F Pollock, Lisa M Meckley
Introduction: While most individual primary immunodeficiency diseases (PID) are rare, the collective prevalence of PID results in a substantial economic and clinical burden. The aim of this study was to evaluate the budgetary implications of Ig20Gly (Immune Globulin Subcutaneous [human] 20% solution; CUVITRU ® , Baxalta US Inc, now part of Shire Plc, Westlake Village, CA, USA) as a treatment for PID relative to intravenous immunoglobulin (IVIG) and other subcutaneous immunoglobulin (SCIG) formulations in the Swiss health care setting...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29580629/rates-of-echocardiography-coronary-angiography-and-coronary-intervention-associated-with-troponin-testing-in-hospitalized-patients
#6
Gibbs Wilson, Kevin Kurian, Syed Zamin, Jonathan Urbanczyk, Travis Haneke, Cameron Simonsen, Sachin Mehta, Mitta Suresh, Jeffrey Michel
Diagnosis of acute myocardial infarction (AMI) often depends on detection of cardiac troponin elevation >99th percentile. However, troponin elevation is commonly found in patients without AMI. We have previously reported an association between troponin elevation and rates of electrocardiogram (ECG), echocardiography (ECHO), and coronary angiography (CAG) in patients with a primary diagnosis of sepsis. We hypothesized that elevated troponin might be associated with greater use of ECHO and CAG in primary diagnoses other than sepsis and that this correlation might also include percutaneous coronary intervention (PCI)...
March 2, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29579040/sensitive-and-specific-detection-of-crimean-congo-hemorrhagic-fever-virus-cchfv-specific-igm-and-igg-antibodies-in-human-sera-using-recombinant-cchfv-nucleoprotein-as-antigen-in-%C3%AE-capture-and-igg-immune-complex-ic-elisa-tests
#7
Petra Emmerich, Angela Mika, Ronald von Possel, Anne Rackow, Yang Liu, Herbert Schmitz, Stephan Günther, Kurtesh Sherifi, Barie Halili, Xhevat Jakupi, Lindita Berisha, Salih Ahmeti, Christina Deschermeier
As the most widespread tick-borne arbovirus causing infections in numerous countries in Asia, Africa and Europe, Crimean-Congo Hemorrhagic Fever Virus (CCHFV, family Nairoviridae) was included in the WHO priority list of emerging pathogens needing urgent Research & Development attention. To ensure preparedness for potential future outbreak scenarios, reliable diagnostic tools for identification of acute cases as well as for performance of seroprevalence studies are necessary. Here, the CCHFV ortholog of the major bunyavirus antigen, the nucleoprotein (NP), was recombinantly expressed in E...
March 26, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29564300/review-of-epidemiology-diagnosis-and-treatment-of-osteosarcopenia-in-korea
#8
REVIEW
Jun-Il Yoo, Yong-Chan Ha
Sarcopenia was listed in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) as M62.84, on October 1, 2016. Sarcopenia is primarily associated with metabolic diseases, such as diabetes, obesity, and cachexia, as well as chronic renal failure, congestive heart failure, and chronic obstructive pulmonary disease. Sarcopenia is also significantly associated with osteoporosis in elderly populations and the combined disease is defined as osteosarcopenia. Several studies have confirmed that sarcopenia and osteoporosis (osteosarcopenia) share common risk factors and biological pathways...
February 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29543305/mortality-of-patients-hospitalized-for-active-tuberculosis-in-king-abdulaziz-university-hospital-jeddah-saudi-arabia
#9
Ahmed A Aljohaney
OBJECTIVES: To determine the mortality rates and predictors among patients hospitalized with active tuberculosis (TB) at King Abdulaziz University Hospital (KAUH) in Jeddah. METHODS: A retrospective study was performed on 291 active TB patients hospitalized in KAUH, Jeddah, Saudi Arabia from December 2011 to December 2016. Medical records were collected and evaluated using a dedicated data extraction sheet. The records included demographics, clinical, radiological, laboratory, and drug resistance data...
March 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29534402/-multicenter-retrospectie-analysis-on-clinical-characteristics-and-pharmaceutical-therapy-of-elderly-patients-with-chronic-heart-failure
#10
L Li, Q Mo, T Mo, Y Liu, J L Tian, Z Wan
Objective: To investigate the clinical characteristics and pharmaceutical therapy of elderly patients with chronic heart failure (CHF). Methods: Using the multi-center retrospective cross-sectional survey, we analyzed 1 799 hospitalized patients with CHF as the main cause and NYHA heart function classification Ⅱ-Ⅳ from nine tertiary hospitals of Tianjin during March 2014 to February 2016. According to age, we divided them into non- elderly group(age<65 years), normal elderly group (age ≥65-79 years), and the old elderly group(age≥80 years)...
March 6, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29525333/innovation-in-heart-failure-treatment-life-expectancy-disability-and-health-disparities
#11
Karen E Van Nuys, Zhiwen Xie, Bryan Tysinger, Mark A Hlatky, Dana P Goldman
OBJECTIVES: The goal of this study was to illustrate the potential benefit of effective congestive heart failure (CHF) treatment in terms of improved health, greater social value, and reduced health disparities between black and white subpopulations. BACKGROUND: CHF affects 5.7 million Americans, costing $32 billion annually in treatment expenditures and lost productivity. CHF also contributes to health disparities between black and white Americans: black subjects develop CHF at a younger age and are more likely to be hospitalized and die of this disease...
May 2018: JACC. Heart Failure
https://www.readbyqxmd.com/read/29523437/active-smoking-in-claudicants-undergoing-lower-extremity-bypass-predicts-decreased-graft-patency-and-worse-overall-survival
#12
Douglas W Jones, Philip P Goodney, Jens Eldrup-Jorgensen, Marc L Schermerhorn, Jeffrey J Siracuse, Jeanwan Kang, Jesse A Columbo, Bjoern D Suckow, David H Stone
OBJECTIVE: Performing lower extremity bypass (LEB) in actively smoking claudicants remains controversial. Whereas some surgeons advocate a strict nonoperative approach to active smokers, citing perceived inferior outcomes, others will proceed with surgical bypass if the patient is anatomically suited and medical management has failed. The purpose of this study was to determine the impact of active smoking on LEB outcomes among claudicants. METHODS: All patients undergoing infrainguinal LEB for claudication in the Vascular Study Group of New England from 2003 to 2016 were analyzed...
March 6, 2018: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29508361/surgical-chylothorax-in-neonates-management-and-outcomes
#13
Karina Miura Costa, Amulya Kumar Saxena
BACKGROUND: Postoperative chylothorax occurs due to trauma to lymphatic vessels and can occur after any thoracic procedure. This study reviewed recent literature to evaluate the management and outcomes of surgical chylothorax in neonates. METHODS: PubMed database was searched for articles in English, Portuguese and Spanish from 2000 to 2016. Data were collected for surgery, chylothorax management, complications, mortality and length of hospital stay (LOS). RESULTS: Twenty studies offered 107 neonates: congenital diaphragmatic hernia (CDH) (n = 76, 71%), cardiac malformations (n = 25, 23...
April 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29495123/an-updated-systematic-review-and-meta-analysis-of-early-outcomes-after-left-atrial-appendage-occlusion
#14
Charan Yerasi, Mohamad Lazkani, Prathik Kolluru, Varun Miryala, Jae Kim, Harsha Moole, Abhishek C Sawant, Michael Morris, Ashish Pershad
BACKGROUND: Left atrial appendage occlusion (LAAO) is a promising intervention for stroke prevention in patients with non-valvular atrial fibrillation (NVAF). Early outcomes following LAAO have been published in many studies with variable results. OBJECTIVE: This updated meta-analysis aims to provide a summary of the early outcomes of LAAO. METHODS: Medline/Pubmed, Ovid Journals, Clinical trials, Abstract meetings, Cochrane databases were searched from January 1st, 1999 to November 30th, 2016...
April 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29490874/risk-factors-for-the-development-of-incident-atrial-fibrillation-in-patients-with-cardiac-implantable-electronic-devices
#15
Kazuo Miyazawa, Yusuke Kondo, Miyo Nakano, María Asunción Esteve-Pastor, José Miguel Rivera-Caravaca, Keitaro Senoo, Yoshio Kobayashi, Gregory Y H Lip
INTRODUCTION: Cardiac implantable electronic devices (CIEDs) can detect atrial fibrillation (AF) early and accurately. Risk factors for the development of new-onset AF in patients with CIEDs remains uncertain. METHODS: Patients with CIEDs who visited Chiba University Hospital between January 2016 and December 2016 were enrolled. We only included patients without single chamber CIEDs or a known history of AF. RESULTS: Of 371 patients with CIEDs, 78 (21...
February 26, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29490333/association-of-body-mass-index-with-lifetime-risk-of-cardiovascular-disease-and-compression-of-morbidity
#16
Sadiya S Khan, Hongyan Ning, John T Wilkins, Norrina Allen, Mercedes Carnethon, Jarett D Berry, Ranya N Sweis, Donald M Lloyd-Jones
Importance: Prior studies have demonstrated lower all-cause mortality in individuals who are overweight compared with those with normal body mass index (BMI), but whether this may come at the cost of greater burden of cardiovascular disease (CVD) is unknown. Objective: To calculate lifetime risk estimates of incident CVD and subtypes of CVD and to estimate years lived with and without CVD by weight status. Design, Setting, and Participants: In this population-based study, we used pooled individual-level data from adults (baseline age, 20-39, 40-59, and 60-79 years) across 10 large US prospective cohorts, with 3...
April 1, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29486762/outcomes-and-costs-of-ranibizumab-and-aflibercept-treatment-in-a-health-service-research-context
#17
Martin K Schmid, Oliver Reich, Eva Blozik, Livia Faes, Nicolas S Bodmer, Silvan Locher, Michael A Thiel, Roland Rapold, Maximilian Kuhn, Lucas M Bachmann
BACKGROUND: To compare anti-VEGF treatments for macular disease in terms of costs and clinical outcomes. METHODS: We identified patients suffering from macular disease and treated either with aflibercept, ranibizumab or both at the largest public eye clinic in Switzerland between January 1st and December 31st 2016 who were insured in one of the two participating health insurance companies. Clinical data were extracted from the electronic health record system. The health insurers provided the health claim costs for the ophthalmologic care and the total health care costs of each patient in the observation period...
February 27, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29485952/the-effect-of-opioid-use-and-mental-illness-on-chronic-disease-medication-adherence-in-superutilizers
#18
Satya Surbhi, Ilana Graetz, Jim Y Wan, Justin Gatwood, James E Bailey
BACKGROUND: Nonadherence to essential chronic medications has been identified as a potential driver of high health care costs in superutilizers of inpatient services. Few studies, however, have documented the levels of nonadherence and factors associated with nonadherence in this high-cost, vulnerable population. OBJECTIVE: To examine the factors associated with nonadherence to essential chronic medications, with special emphasis on mental illness and use of opioid medications...
March 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29469206/impact-of-sacubitril-valsartan-combination-in-patients-with-chronic-heart-failure-and-sleep-apnoea-syndrome-the-entresto-sas-study-design
#19
Dany Jaffuel, Nicolas Molinari, Philippe Berdague, Atul Pathak, Michel Galinier, Marion Dupuis, Jean-Etienne Ricci, Jean-Pierre Mallet, Arnaud Bourdin, François Roubille
AIMS: Sleep-disordered breathing (SDB) is a highly prevalent co-morbidity in patients with chronic heart failure (CHF) and can play a detrimental role in the pathophysiology course of CHF. However, the best way to manage SDB in CHF remains a matter of debate. Sacubitril-valsartan has been included in the 2016 European Society of Cardiology guidelines as an alternative to angiotensin-converting enzyme inhibitors to further reduce the risk of progression of CHF, CHF hospitalization, and death in ambulatory patients...
June 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29441746/long-term-prognosis-and-clinical-characteristics-of-patients-with-newly-diagnosed-diabetes-mellitus-detected-after-first-acute-myocardial-infarction-from-kamir-nih-registry
#20
Hyun Woong Park, Min Gyu Kang, Kyehwan Kim, Jin Sin Koh, Jeong Rang Park, Young Hoon Jeong, Jong Hwa Ahn, Jeong Yoon Jang, Choong Hwan Kwak, Yongwhi Park, Myung Ho Jeong, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim, Jin Yong Hwang
BACKGROUND AND OBJECTIVES: After the first acute myocardial infarction (AMI), a considerable proportion of patients are newly diagnosed with diabetes mellitus (DM). However, in AMI, controversy remains regarding the disparity in prognosis between previously diagnosed DM (known-DM) and newly diagnosed DM (new-DM). METHODS: The study included 10,455 patients with AMI (non-DM, 6,236; new-DM, 659; known-DM, 3,560) admitted to one of 15 participating centers in Korea between November 2011 and January 2016 (average follow-up, 523 days)...
February 2018: Korean Circulation Journal
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