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https://www.readbyqxmd.com/read/27924129/interplay-of-genes-in-plant-pathogen-interactions-in-planta-expression-and-docking-studies-of-a-beta-1-3-glucanase-gene-from-piper-colubrinum-and-a-glucanase-inhibitor-gene-from-phytophthora-capsici
#1
K Johnson George, O Rosana Babu, I P Vijesh Kumar, J Santhosh Eapen, M Anandaraj
Oomycete pathogen, Phytophthora capsici is devastating for black pepper (Piper nigrum L.) and causes foot rot disease at all stages of plant growth. Phytophthora secretes a glucanase inhibitor protein (GIP), which is capable of inhibiting defence proteins like endoglucanases. In this particular study Quantitative PCR analysis, molecular docking studies and analysis of sequences of Glucanase inhibitor protein and beta-1,3 glucanse genes were done mainly depending on the data derived from Phytophthora capsici whole genome sequencing and Piper colubrinum RNA-sequencing (RNA-Seq)...
October 2016: Physiology and Molecular Biology of Plants: An International Journal of Functional Plant Biology
https://www.readbyqxmd.com/read/27923215/timing-of-antibiotic-prophylaxis-for-preventing-surgical-site-infections-in-foot-and-ankle-surgery
#2
Direk Tantigate, Eugene Jang, Mani Seetharaman, Peter C Noback, A M Heijne, Justin K Greisberg, J Turner Vosseller
BACKGROUND: Surgical site infections (SSIs) are one of the most troublesome complications after foot and ankle surgery. Previous literature has emphasized the significance of appropriate timing of antibiotic prophylaxis. However, the optimal timing of antibiotic prophylaxis for SSI prevention is still inconclusive. Our study aimed to investigate the optimal timing of antibiotic administration and to elucidate the risk factors for SSIs in foot and ankle surgery. METHODS: A retrospective review of 1933 foot and ankle procedures in 1632 patients from January 1, 2011, through August 31, 2015, was performed...
October 23, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27919488/clinical-assessment-of-gait-in-individuals-with-multiple-sclerosis-using-wearable-inertial-sensors-comparison-with-patient-based-measure
#3
Massimiliano Pau, Silvia Caggiari, Alessandro Mura, Federica Corona, Bruno Leban, Giancarlo Coghe, Lorena Lorefice, Maria Giovanna Marrosu, Eleonora Cocco
BACKGROUND: This study aims to verify the feasibility of use of wearable accelerometers in an ambulatory environment to assess spatiotemporal parameters of gait in people with Multiple Sclerosis (pwMS), as well as the correlation of objective data with patient-reported outcomes. METHODS: One hundred and five pwMS (Expanded Disability Status Scale, EDSS in the range 0-6.5) classified in three sub-groups (EDSS 0-1.5, EDSS 2-4, EDSS 4.5-6.5) and 47 healthy controls (HC) participated in the study...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27909861/surgical-reconstruction-for-fibular-hemimelia
#4
REVIEW
Dror Paley
Fibular hemimelia presents with foot deformity and leg length discrepancy. Previous classifications have focused on the degree of fibular deficiency rather than the type of foot deformity. Published methods of surgical reconstruction have often failed due to residual or recurrent foot deformity. The purpose of this report is to introduce new classification and reconstruction methods. The Paley SHORDT procedure is used to stabilize the ankle when there is a hypoplastic distal fibula with a dynamic valgus deformity...
December 1, 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27909391/visual-behavior-differences-in-drivers-across-the-lifespan-a-digital-billboard-simulator-study
#5
Despina Stavrinos, Peyton R Mosley, Shannon M Wittig, Haley D Johnson, John S Decker, Virginia P Sisiopiku, Sharon C Welburn
Driver distraction is implicated in a significant portion of motor vehicle collisions; evidence has suggested that billboards can contribute to such distraction, but many knowledge gaps remain. The purpose of this study was to evaluate the effects of various types of billboards (static, 250-foot digital transition, 500-foot digital transition, and a control [no billboard] condition) and age group (teen, middle, and older) on visual behavior through the use of a driving simulator. To address gaps in the existing literature, the effects of age group and billboard type on the following visual attention variables were considered: percent of time participants looked at billboards, average glance length, number of glances, and glance pattern activity...
August 2016: Transportation Research. Part F, Traffic Psychology and Behaviour
https://www.readbyqxmd.com/read/27904023/early-embryonic-development-of-long-tendons-in-the-human-foot
#6
Masahito Yamamoto, Yasuhiro Shiraishi, Kei Kitamura, Zhe Wu Jin, Gen Murakami, Jose Francisco Rodríguez-Vázquez, Shin-Ichi Abe
To examine a common plantar tendinous plate for long flexors of the toe and fingers in human embryos, we observed sections of 10 embryos at 5-6 weeks (crown-rump length or CRL 15-21 mm). The heel or tuber of the calcaneus was underdeveloped in 3 embryos with CRL 15 mm and the talus appeared not to be piled up on the calcaneus but these two bones were arranged along the lateromedial axis. As reported in the hand, we demonstrated, in the deep side of tarsal bones, a common tendinous plate formed by a joining of the flexor halluces longus and flexor digitorum longus tendons...
2016: Okajimas Folia Anatomica Japonica
https://www.readbyqxmd.com/read/27903628/the-role-of-plantigrady-and-heel-strike-in-the-mechanics-and-energetics-of-human-walking-with-implications-for-the-evolution-of-the-human-foot
#7
James T Webber, David A Raichlen
Human bipedal locomotion is characterized by a habitual heel-strike (HS) plantigrade gait, yet the significance of walking foot-posture is not well understood. To date, researchers have not fully investigated the costs of non-heel-strike (NHS) walking. Therefore, we examined walking speed, walk-to-run transition speed, estimated locomotor costs (lower limb muscle volume activated during walking), impact transient (rapid increase in ground force at touchdown) and effective limb length (ELL) in subjects (n=14) who walked at self-selected speeds using HS and NHS gaits...
December 1, 2016: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27895574/robot-assisted-rehabilitation-of-ankle-plantar-flexors-spasticity-a-3-month-study-with-proprioceptive-neuromuscular-facilitation
#8
Zhihao Zhou, Yao Sun, Ninghua Wang, Fan Gao, Kunlin Wei, Qining Wang
In this paper, we aim to investigate the effect of proprioceptive neuromuscular facilitation (PNF)-based rehabilitation for ankle plantar flexors spasticity by using a Robotic Ankle-foot Rehabilitation System (RARS). A modified robot-assisted system was proposed, and seven poststroke patients with hemiplegic spastic ankles participated in a 3-month robotic PNF training. Their impaired sides were used as the experimental group, while their unimpaired sides as the control group. A robotic intervention for the experimental group started from a 2-min passive stretching to warming-up or relaxing the soleus and gastrocnemius muscles and also ended with the same one...
2016: Frontiers in Neurorobotics
https://www.readbyqxmd.com/read/27890336/complications-and-revision-amputation-following-trauma-related-lower-limb-loss
#9
Eric Edison Low, Elizabeth Inkellis, Saam Morshed
INTRODUCTION: Trauma-related amputations are a common cause of limb loss in the United States. Despite the military and public health impact of trauma-related amputations, distributions of various lower limb amputations and the relative frequency of complications and revision amputations have not been well described. We used the National Trauma Data Bank (NTDB) in order to investigate the epidemiology of trauma-related lower extremity amputations among civilians in U.S. trauma centers...
November 18, 2016: Injury
https://www.readbyqxmd.com/read/27890134/the-relationship-between-arch-height-and-foot-length-implications-for-size-grading
#10
Matthew Hill, Roozbeh Naemi, Helen Branthwaite, Nachiappan Chockalingam
OBJECTIVE: Medial longitudinal Arch Height is synonymous with classifying foot type and conversely foot function. Detailed knowledge of foot anthropometry is essential in the development of ergonomically sound footwear. Current Footwear design incorporates a direct proportionate scaling of instep dimensions with those of foot length. The objective of this paper is to investigate if a direct proportional relationship exists between human arch height parameters and foot length in subjects with normal foot posture...
March 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/27881742/association-of-abnormal-metatarsal-parabola-with-second-metatarsophalangeal-joint-plantar-plate-pathology
#11
Adam E Fleischer, Erin E Klein, Maheen Ahmad, Shivang Shah, Fernanda Catena, Lowell Scott Weil, Lowell Weil
BACKGROUND: Plantar plate pathology is common, yet it is unclear whether, and to what extent, the length of the second metatarsal contributes to this problem. METHODS: We conducted a retrospective case-control (1:2) study to examine radiographic risk factors for plantar plate tears. One hundred patients (age 55.7 ± 12.3 years) with plantar plate injuries and 200 healthy controls (age 56.3 ± 11.3 years) were included. Cases were defined as patients with nonacute, isolated, plantar plate pathology of the second metatarsophalangeal joint confirmed by intraoperative inspection at a single foot and ankle specialty practice from June 1, 2007, to January 31, 2014...
November 22, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27879456/hindlimb-spasticity-after-unilateral-motor-cortex-lesion-in-rats-is-reduced-by-contralateral-nerve-root-transfer
#12
Hai Yang Zong, Fenfen Ma, Lai Yin Zhang, Hui Ping Lu, Jing Ru Gong, Min Cai, Hao Dong Lin, Yizhun Zhun Zhu, Chun Lin Hou
The aim was to test the feasibility and effectiveness of contralateral nerve root transfer in reducing post stroke spasticity of the affected hindlimb muscles in rats. In our study, we for the first time created a novel animal hindlimb spastic hemiplegia model in rats with photothrombotic lesion of unilateral motor cortex and we established a novel surgical procedure in reducing motor cortex lesion induced hindlimb spastic hemiplegia in rats. Thirty six rats were randomized into three groups. In group A, rats received sham operation...
November 22, 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27878457/poorly-understood-and-often-miscategorized-congenital-umbilical-cord-hernia-an-alternative-repair-method
#13
E İnce, A Temiz, S S Ezer, H Ö Gezer, A Hiçsönmez
PURPOSE: Umbilical cord hernia is poorly understood and often miscategorized as "omphalocele minor". Careless clamping of the cord leads to iatrogenic gut injury in the situation of umbilical cord hernia. This study aimed to determine the characteristics and outcomes of umbilical cord hernias. We also highlight an alternative repair method for umbilical cord hernias. METHODS: We recorded 15 cases of umbilical cord hernias over 10 years. The patients' data were retrospectively reviewed, and preoperative preparation of the newborn, gestational age, birth weight, other associated malformations, surgical technique used, enteral nutrition, and length of hospitalization were recorded...
November 22, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/27878341/initiation-of-forward-gait-with-lateral-occurrence-of-emotional-stimuli-general-findings-and-relevance-for-pedestrians-crossing-roads
#14
D Caffier, C Gillet, L P Heurley, A Bourrelly, F Barbier, J Naveteur
With reference to theoretical models regarding links between emotions and actions, the present study examined whether the lateral occurrence of an emotional stimulus influences spatial and temporal parameters of gait initiation in 18 younger and 18 older healthy adults. In order to simulate road-crossing hazard for pedestrians, slides of approaching cars were used and they were presented in counterbalanced order with threatening slides from the International Affective Picture System (IAPS) and control slides of safe walking areas...
November 22, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/27871591/continuous-intra-articular-local-anesthetic-drug-instillation-versus-discontinuous-sciatic-nerve-block-after-total-knee-arthroplasty
#15
Johannes Cip, Hedwig Erb-Linzmeier, Peter Stadlbauer, Christian Bach, Arno Martin, Reinhard Germann
STUDY OBJECTIVE: Sciatic nerve block (SNB) is commonly used as adjunct to femoralis nerve block (FNB) to achieve high-quality pain relief after total knee arthroplasty (TKA). However, this combination is associated with considerable muscle weakness, foot drop and surgically related nerve injuries may be masked. The purpose of this study was to assess whether low risk continuous intra-articular anesthetic drug instillation is an adequate alternative to SNB when adding to FNB after TKA...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27863443/gait-assessment-with-solesound-instrumented-footwear-in-spinal-muscular-atrophy
#16
Jacqueline Montes, Damiano Zanotto, Sally Dunaway Young, Rachel Salazar, Darryl C De Vivo, Sunil Agrawal
BACKGROUND: Gait impairment is common in spinal muscular atrophy (SMA) and is described using clinical assessments and instrumented walkways. Continuous over-ground walking has not been studied. METHODS: Nine SMA participants completed the six-minute walk test (6MWT) and 10-meter walk/run wearing instrumented footwear (SoleSound). Data were simultaneously collected using a reference system (GAITRite(TM) ). The root mean square error (RMSE) indicated criterion validity...
November 18, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862471/assessment-of-passive-muscle-elongation-using-diffusion-tensor-mri-correlation-between-fiber-length-and-diffusion-coefficients
#17
Valentina Mazzoli, Jos Oudeman, Klaas Nicolay, Mario Maas, Nico Verdonschot, Andre M Sprengers, Aart J Nederveen, Martijn Froeling, Gustav J Strijkers
In this study we investigated the changes in fiber length and diffusion parameters as a consequence of passive lengthening and stretching of the calf muscles. We hypothesized that changes in radial diffusivity (RD) are caused by changes in the muscle fiber cross sectional area (CSA) as a consequence of lengthening and shortening of the muscle. Diffusion Tensor MRI (DT-MRI) measurements were made twice in five healthy volunteers, with the foot in three different positions (30° plantarflexion, neutral position and 15° dorsiflexion)...
November 8, 2016: NMR in Biomedicine
https://www.readbyqxmd.com/read/27858688/characteristics-of-foot-morphology-and-their-relationship-to-gender-age-body-mass-index-and-bilateral-asymmetry-in-japanese-adults
#18
Xiaoguang Zhao, Takehiko Tsujimoto, Bokun Kim, Yasutomi Katayama, Kiyoji Tanaka
BACKGROUND: Different characteristics of foot morphology are commonly accompanied by altering lower extremity biomechanical characteristics and foot function. Clarifying what factors affect foot morphology is helpful in understanding the basis of foot deformity and foot dysfunction. OBJECTIVE: The aim of this study was to investigate characteristics of foot morphology and whether related factors such as gender, age, body mass index (BMI) and bilateral asymmetry have an impact on foot morphology...
November 11, 2016: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/27847806/surgical-strategy-for-the-chronic-achilles-tendon-rupture
#19
Yangjing Lin, Liu Yang, Li Yin, Xiaojun Duan
Background. Chronic Achilles tendon rupture is usually misdiagnosed and treated improperly. This study aims to better understand the treatment of chronic Achilles tendon rupture. Methods. Patients who were not able to perform a single-limb heel rise were chosen. Pre- and postoperative magnetic resonance imaging (MRI) were conducted. By evaluating the presence or absence of Achilles tendon stumps and the gap length of rupture, V-Y advancement, gastrocnemius fascial turndown flap, or flexor halluces longus tendon transfer were selected for tendon repair...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27846434/how-far-do-stabilometric-and-clinical-parameters-correlate-in-peripheral-neuropathies
#20
REVIEW
Ana Flavia Gomes Paiva, Philippe Thoumie, Besma Missaoui
Peripheral neuropathies are characterized by the impairment of motor and sensitive nervous fibers. We aimed to investigate the correlation between proprioception, force and the limits of equilibrium parameter (LOE), by assessing 38 patients diagnosed with characterized bilateral neuropathy and 11 healthy subjects. Clinical evaluation, based on a motor and pallesthesic score, enabled their classification into groups corresponding to motor, sensitive or mixed neuropathies. Balance measures on a stabilometric platform allowed differentiation between the patients and healthy subjects but not between the groups of patients...
November 9, 2016: Gait & Posture
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