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Muhammad Ibrahim, Kanwal Rehman, Aneeza Razzaq, Iqbal Hussain, Tahir Farooq, Amjad Hussain, Muhammad Sajid Hamid Akash
The genus Urtica belongs to the family Urticaceae. The plants of this genus are known as nettles or, quite often, as stinging nettles. These plants can be easily identified by the presence of stinging hairs. Urtica species have previously been used for various medicinal purposes. The history for the use of these plants for medicinal purposes starts from the Bronze Age (3000-2000 BC). Medicinally, the genus Urtica has been used to treat several disorders, such as cancer, rheumatoid arthritis, bronchitis, diarrhea, sprains, kidney stones, urinary tract infection, high blood pressure, hemorrhoids, flu, cough, fever, and ulcers...
2018: Critical Reviews in Eukaryotic Gene Expression
Florent Jasinski, Amjad Alkhater, Stuart C Thickett, Richard H Brinkhuis, Per B Zetterlund
Copolymer/water interfacial tensions of statistical copolymers of styrene / n-butyl acrylate were estimated by pendant drop tensiometry using an "inverse" configuration according to which a drop of water was formed in toluene/copolymer solutions. The study first involved the precise measurement of copolymer solutions density using pycnometry. Subsequently, interfacial tensions of copolymer solutions against water were plotted as a function of copolymer concentration in toluene. Several methods were explored to fit the experimental data and obtain estimates of copolymer/water interfacial tensions at 100 % copolymer concentration in toluene by extrapolation...
May 17, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
Amjad Sattar, Sohail Ahmed Khan, Nauman Al-Qamari, Hatem Adel, Syed Omair Adil, Kashif Shafique
BACKGROUND: Chest computed tomography (CT), including high-resolution CT (HRCT), has become an integral part of modern healthcare. It enables the physician to arrive at a diagnosis using a noninvasive approach. Our practice has shown that various chest CT scans without intravenous (IV) contrast, including HRCT, have no proper clinical indication. For the same reason, we have assessed the appropriateness of chest CT without IV contrast based on the evidence-based American College of Radiology (ACR) appropriateness criteria...
March 28, 2018: Respiratory Investigation
Karem H Alzoubi, Enas Mokhemer, Amjad N Abuirmeileh
The aim of this study was to evaluate etazolate against depression-like behavior and, learning and memory impairment induced by 6- hydroxydopamine (6-OHDA) rat model of Parkinson's disease (PD). This aim was achieved through comparing 6-OHDA lesioned rats in the presence and absence of etazolate. The 6-OHDA was used to induce lesion as a model of PD. Etazolate was administered at a dose of 1 mg/kg/day for 14 days, starting 7 days after lesion induction. Apomorphine-induced rotation test was used to evaluate 6-OHDA-induced motor deficits, tail suspension test was used to assess depression-like symptoms, and the radial arms water maze (RAWM) was used to evaluate special learning and memory functions...
May 11, 2018: Behavioural Brain Research
Muhammad Amjad Pervez, Dishad Ahmet Khan, Aamir Ijaz, Shamrez Khan
BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem worldwide and is associated with increased morbidity and mortality. Currently, there is no definitive treatment for this disease. δ-Tocotrienol has potent anti-inflammatory and antioxidant properties and may reduce liver injury in NAFLD. The present study aims to evaluate the efficacy and safety of δ-tocotrienol in the treatment of NAFLD. MATERIALS AND METHODS: The present study was a randomized, double-blind, placebo-controlled pilot study conducted in patients aged > 20 years, belonging to both sexes, having ultrasound-proven fatty liver disease, having a fatty liver index (FLI) of ≥ 60, and persistent elevation of alanine transaminase...
March 2018: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
Amjad I Hussain, Andreas Auensen, Cathrine Brunborg, Jan Otto Beitnes, Lars Gullestad, Kjell I Pettersen
OBJECTIVES: This study addressed the assumption of increased morbidity and mortality after surgical aortic valve replacement in patients older than 80 years with severe aortic stenosis. METHODS: This prospective study was performed in consecutive patients referred for aortic valve replacement. The age-dependent change in cognitive and physical function, quality of life and rehospitalization and complication rates during the following year and 5-year all-cause mortality were documented...
May 9, 2018: Interactive Cardiovascular and Thoracic Surgery
Tanner C Godfrey, Benjamin J Wildman, Amjad Javed, Christopher J Lengner, Mohammad Quamarul Hassan
Current studies offer little insight on how epigenetic remodeling of bone-specific chromatin maintains bone mass in vivo. Understanding this gap and precise mechanism is pivotal for future therapeutic innovation to prevent bone loss. Recently, we found that low bone mass is associated with decreased H3K27 acetylation (activating histone modification) of bone specific gene promoters. Here, we aim to elucidate the epigenetic mechanisms by which a miRNA cluster controls bone synthesis and homeostasis by regulating chromatin accessibility and H3K27 acetylation...
December 2018: Connective Tissue Research
Haruka Yoshie, Newsha Koushki, Rosa Kaviani, Mohammad Tabatabaei, Kavitha Rajendran, Quynh Dang, Amjad Husain, Sean Yao, Chuck Li, John K Sullivan, Magali Saint-Geniez, Ramaswamy Krishnan, Allen J Ehrlicher
Actomyosin contractility is an essential element of many aspects of cellular biology and manifests as traction forces that cells exert on their surroundings. The central role of these forces makes them a novel principal therapeutic target in diverse diseases. This requires accurate and higher-capacity measurements of traction forces; however, existing methods are largely low throughput, limiting their utility in broader applications. To address this need, we employ Fourier-transform traction force microscopy in a parallelized 96-well format, which we refer to as contractile force screening...
May 8, 2018: Biophysical Journal
Shahid Hussain Farooqi, Muhammad Ijaz, Muhammad Imran Rashid, H Nabi, S Islam, Amjad Islam Aqib, Kashif Hussain, Amjad Khan, Syeda Nayab Batool Rizvi, Shakeel Mahmood, Khalid Mehmood, Hui Zhang
Bovine anaplasmosis is endemic in Pakistan where it reduces livestock productivity and leads to high mortality, especially in young animals. This study was aimed to identify the potential risk factors responsible for the occurrence and spread of anaplasmosis in cattle and buffaloes for the first time in Pakistan. A total of 900 (cattle = 479, buffalo = 421) blood samples were collected irrespective of age and sex from three distinct zones of Khyber Pakhtunkhhwa (KP) province of Pakistan. Polymerase chain reaction (PCR) technique was used for the molecular detection of anaplasmosis...
May 8, 2018: Tropical Animal Health and Production
Muhammad Amjad Khan, Xiaodong Ding, Sardar Khan, Mark L Brusseau, Anwarzeb Khan, Javed Nawab
Mining of minerals and precious elements leads to land degradation that need to be reclaimed using environmentally friendly and cost effective techniques. The present study investigated the potential effects of different organic amendments on cadmium (Cd) bioavailability in mining-degraded soil and its subsequent bioaccumulation in tomato and cucumber. The selected organic geosorbents (hard wood biochar (HWB), bagasse (BG), rice husk (RH), and maize comb waste (MCW)) were added at application rates of 3% and 5% to chromite mine-degraded soil containing Cd...
May 1, 2018: Science of the Total Environment
Nafees Ahmad, Amer Hayat Khan, Irfanullah Khan, Amjad Khan, Muhammad Atif
Aim: To evaluate doctors' knowledge, attitude, and practices and predictors of adherence to Malaysian hypertension guidelines (CPG 2008). Methods: Twenty-six doctors involved in hypertension management at Penang General Hospital were enrolled in a cross-sectional study. Doctors' knowledge and attitudes towards guidelines were evaluated through a self-administered questionnaire. Their practices were evaluated by noting their prescriptions written to 520 established hypertensive outpatients (20 prescriptions/doctor)...
2018: International Journal of Hypertension
Eunji Kim, Young-Su Yi, Young-Jin Son, Sang Yun Han, Dong Hyun Kim, Gibaeg Nam, Mohammad Amjad Hossain, Jong-Hoon Kim, Junseong Park, Jae Youl Cho
No abstract text is available yet for this article.
April 2018: Journal of Ginseng Research
Basma Damiri, Mohammed S Abualsoud, Amjad M Samara, Sakhaa K Salameh
Background: Metabolic syndrome (MetS) is one of the main reasons for elevated cardiovascular morbidity and mortality worldwide. Obese and overweight individuals are at high risk of developing these chronic diseases. The aim of this study was to characterize and establish sex-adjusted prevalence of metabolic syndrome and its components. Methods: A cross-sectional study was conducted in 2015, 689 (329 men and 360 women) aged 18-65 years from three refugee camps in the West Bank...
2018: Diabetology & Metabolic Syndrome
Ghobad Moradi, Mohammad-Mehdi Gouya, Fatemeh Azimizan, Amjad Mohamadi Bolbanabad, Sonia Darvishi, Mohammad Reza Aghasadeghi, Mahmood Nabavi, Ramin Alasvand, Mehrzad Tashakorian, Bijan Nouri, Khaled Rahmani, Leila Molaei
OBJECTIVES: To provide more accurate estimates of the prevalence of Hepatitis B (HBV) and Hepatitis C (HCV) and their contributing factors among prisoners in Iran. METHODS: Cross-sectional study of 6200 Iranian prisoners in 2015. Data were collected through questionnaires and interviews. HBV infection and HCV exposure status of the participants was determined by HBsAg and HCV antibodies blood tests using Enzyme-Linked Immunosorbent Assay (ELISA). Data were analyzed in STATA-12...
April 26, 2018: Tropical Medicine & International Health: TM & IH
Komal Saleem, Braira Wahid, Amjad Ali, Shazia Rafique, Zara Naz, Sana Usman, Muhammad Idrees
Direct-acting antivirals (DAAs) have been proved as potent agents in the new era of Hepatitis C therapeutics. DAA has evolved to prove highly efficacious treatment rates and sustained virological response in hepatitis C virus (HCV)-treated patients and has shown minimal side effects, but in this study, we reported five cases that showed unusual response toward the use of DAA. The diagnosis was an unusual response of abruptly high viral titers and liver function tests (LFTs) in patients who received DAA combination therapy...
April 25, 2018: Viral Immunology
Safia Jabeen, Zahid Mehmood, Toqeer Mahmood, Tanzila Saba, Amjad Rehman, Muhammad Tariq Mahmood
For the last three decades, content-based image retrieval (CBIR) has been an active research area, representing a viable solution for retrieving similar images from an image repository. In this article, we propose a novel CBIR technique based on the visual words fusion of speeded-up robust features (SURF) and fast retina keypoint (FREAK) feature descriptors. SURF is a sparse descriptor whereas FREAK is a dense descriptor. Moreover, SURF is a scale and rotation-invariant descriptor that performs better in the case of repeatability, distinctiveness, and robustness...
2018: PloS One
Amjad M Husaini, Muhammad Sohail
The challenges of sustainable food production without damaging the environment for a growing human population have increased considerably. The current agricultural practices involving chemical fertilizers and even organic farming are not sustainable in the long run and can have deleterious effects on the environment. Thus, new, innovative solutions need to be identified and propagated for tackling this. Among such innovations, that can complement conventional as well as organic farming methods, are genetic modification (GM) and aquaculture...
2018: Frontiers in Plant Science
Mehwish Waseem, Naveed Yaqoob, Muhammad Iqbal Tariq, Muhammad Qasim Raza, Imran Amjad
OBJECTIVE: To determine the effect of lower limb ergometric training on echocardiographic parameters of left ventricle in dilated cardiomyopathy (DMC) patients. STUDY DESIGN: Randomized control trial. PLACE AND DURATION OF STUDY: Rawalpindi Institute of Cardiology, Rawalpindi, Pakistan, from September 2016 to February 2017. METHODOLOGY: Clinically stable patients with DCM (n=60), were randomly allocated into an interventional group with two-month interventional program and a non-trained control group (n=30 each)...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Muhammad Amjad Ali, Farrukh Azeem, Muhammad Amjad Nawaz, Tuba Acet, Amjad Abbas, Qari Muhammad Imran, Kausar Hussain Shah, Hafiz Mamoon Rehman, Gyuhwa Chung, Seung Hwan Yang, Holger Bohlmann
Plant WRKY transcription factors play a vital role in abiotic stress tolerance and regulation of plant defense responses. This study examined AtWRKY11 and AtWRKY17 expression under ABA, salt, and osmotic stress at different developmental stages in Arabidopsis. We used reverse transcriptase PCR, quantitative real-time PCR, and promoter:GUS lines to analyze expression. Both genes were upregulated in response to abiotic stress. Next, we applied the same stressors to seedlings of T-DNA insertion wrky11 and 17 knock-out mutants (single and double)...
April 17, 2018: Journal of Plant Physiology
Aaisha Amjad, Uzair Amjad, Rubeena Zakar, Ahmed Usman, Muhammad Zakria Zakar, Florian Fischer
BACKGROUND: The increasing rate of caesarean deliveries has become a serious concern for public health experts globally. Various medical and non-medical factors, such as maternal socio-demographics, are found to be responsible for this upsurge. Like in other countries, the rate of caesarean sections has increased in Pakistan as well. Therefore, there is a need to investigate the factors behind this increase. This study aims to assess the determinants associated with caesarean deliveries among child-bearing women aged 15-49 years in Pakistan...
April 23, 2018: BMC Pregnancy and Childbirth
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