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https://www.readbyqxmd.com/read/27908567/the-effect-of-topical-5-flurouracil-application-post-endoscopic-inferior-turbinoplasty
#1
Amjad F Nuseir, Mohammad Alsalem, Mouhamad Alzahr, Muthanna Ababneh, Ahmad I Alomari, Firas Alzoubi
RATIONALE AND OBJECTIVES: Adhesions are the most common complication after nasal surgery and revision. 5-Fluorouracil (5-FU) reduces various adhesions and epithelial growth related complications. The aim of this study was to evaluate the effects of 5-flurouracil application in the nasal cavity after a multi-procedure nasal surgery in term of complications frequency. MATERIALS AND METHODOLOGY: Institutional ethical approval was granted and a double-blinded prospective clinical trial was conducted to study the effect of 5-fu on post-operative complications...
November 23, 2016: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/27908256/a-review-on-nano-antimicrobials-metal-nanoparticles-methods-and-mechanisms
#2
Edris Hoseinzadeh, Pouran Makhdoumi, Parisa Taha, John Stelling, Hooshyar Hossini, Mohammad Amjad Kamal, Ghulam Md Ashraf
Nanotechnology is a scientific and engineering technology conducted at the Nano-scale, such as in the fields of compound fabric manufacturing, food processing, agricultural processing, and engineering, as well as in medical and medicinal application. In recent decade, nanomaterial applications for antimicrobial works have been interested by many researchers. Available reports show that some of the metal oxide Nanoparticles including; Al2O3, TiO2, ZnO, CuO, Co3O4, In2O3, MgO, SiO2, ZrO2, Cr2O3, Ni2O3, Mn2O3, CoO, and Nickel oxide have toxicity toward several microorganisms and they could successfully kill numerous bacteria...
December 1, 2016: Current Drug Metabolism
https://www.readbyqxmd.com/read/27904817/transitional-vertebra-and-spina-bifida-occulta-related-with-chronic-low-back-pain-in-a-young-patient
#3
Maryam Kundi, Maham Habib, Sumbal Babar, Asif K Kundi, Salman Assad, Amjad Sheikh
Bertolotti's syndrome (BS) must be considered as a differential diagnosis in a young patient presenting with low back pain (LBP). We present a case of a 26-year-old male complaining of mild chronic LBP for six years, radiating to his left thigh for the past six months. He has been taking non-steroidal anti-inflammatory drugs (NSAIDs) with skeletal muscle relaxants for pain relief. The X-ray and computed tomography (CT) imagings showed congenital enlargement of the left transverse process of the fifth lumbar (L5) vertebra forming pseudo-articulation with the sacrum and unilateral pars interarticularis defect at the L4 level on the left side, respectively...
October 19, 2016: Curēus
https://www.readbyqxmd.com/read/27899391/atypical-presentation-of-anti-gbm-nephritis-in-a-90-year-old-patient
#4
Julie Omolola Okiro, Chaudhry Adeel Ebad, Amjad Zaman Khan
A 90-year-old woman who had bloody diarrhoea, nausea, weakness and reduced urine output was found to have acute kidney injury. Her inflammatory markers were raised and her chest X-ray suggested an inflammatory process. She was initially suspected to have acute kidney injury secondary to dehydration and sepsis but when her autoimmune screen returned positive for antiglomerular basement membrane antibodies our diagnosis and management strategy was reconsidered. This is a case report of Goodpasture disease presenting in an elderly patient...
November 29, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27899018/corrigendum-to-evolution-and-taxonomy-of-the-wild-species-of-the-genus-ovis-mammalia-artiodactyla-bovidae-mol-phylogenet-evol-54-2-2010-315-326
#5
Hamid Reza Rezaei, Saeid Naderi, Ioana Cristina Chintauan-Marquier, Steve Jordan, Pierre Taberlet, Amjad Tahir Virk, Hamid Reza Naghash, Delphine Rioux, Mohammad Kaboli, Gordon Luikart, François Pompanon
No abstract text is available yet for this article.
November 26, 2016: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/27898702/unit-root-testing-and-estimation-in-nonlinear-estar-models-with-normal-and-non-normal-errors
#6
Umair Khalil, Alamgir, Amjad Ali, Dost Muhammad Khan, Sajjad Ahmad Khan, Zardad Khan
Exponential Smooth Transition Autoregressive (ESTAR) models can capture non-linear adjustment of the deviations from equilibrium conditions which may explain the economic behavior of many variables that appear non stationary from a linear viewpoint. Many researchers employ the Kapetanios test which has a unit root as the null and a stationary nonlinear model as the alternative. However this test statistics is based on the assumption of normally distributed errors in the DGP. Cook has analyzed the size of the nonlinear unit root of this test in the presence of heavy-tailed innovation process and obtained the critical values for both finite variance and infinite variance cases...
2016: PloS One
https://www.readbyqxmd.com/read/27893201/effects-of-tobacco-smoking-on-the-dorsum-of-the-tongue-and-buccal-epithelium
#7
Abdullah Faraj Al Shammari, Ibrahim Khalil AL Ibrahim, Amjad Ibrahim Alaauldeen, Randa Fouad Merza, Hussain Gadelkarim Ahmed
Objective: The aim of this study was to assess the effects of tobacco smoking on the dorsum of the tongue and buccal epithelium. Methodology: This case control cross-sectional study was conducted with 174 smoking and non-smoking volunteers living in the city of Hail, Northern KSA. Cytological Materials were obtained from buccal mucosa and dorsum of the tongue, and assessed using cytopathological methods. Results: In buccal smears, cytological atypia was observed in 17 out of 101 (16.8%) smoker cases but only 3/73(4...
January 10, 2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27881279/the-economic-impact-of-cigarette-smoking-on-the-poor-in-jordan
#8
Amjad M Toukan
OBJECTIVES: To examine the expenditure on cigarette smoking in Jordan and compare the costs with potential investments in food and other essential items. METHODS: Review of available statistics and calculations were performed to estimate the economic cost of cigarette smoking in the Hashemite Kingdom of Jordan. Data on tobacco use and on household expenditures were collected from the Hashemite Kingdom of Jordan official databases. Information on the percentage of adult male smokers in each income group was based on cross-sectional data from 804 adult smokers...
September 2016: Value in Health Regional Issues
https://www.readbyqxmd.com/read/27875971/therapeutic-suppression-of-nonsense-mutation-an-emerging-target-in-multiple-diseases-and-thrombotic-disorders
#9
Md Asiful Islam, Fahmida Alam, Mohammad Amjad Kamal, Siew Hua Gan, Kah Keng Wong, Teguh Haryo Sasongko
Nonsense mutations contribute to approximately 10-30% of the total human inherited diseases via disruption of protein translation. If any of the three termination codons (UGA, UAG and UAA) emerges prematurely [known as premature termination codon (PTC)] before the natural canonical stop codon, truncated non-functional proteins or proteins with deleterious loss or gain-of-function activities are synthesized, followed by the development of nonsense mutation-mediated diseases. In the past decade, PTC-associated diseases captured much attention in biomedical research, especially as molecular therapeutic targets via nonsense suppression (i...
November 22, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27865619/inhibition-on-the-growth-of-human-mda-mb-231-breast-cancer-cells-in-vitro-and-tumor-growth-in-a-mouse-xenograft-model-by-se-containing-polysaccharides-from-pyracantha-fortuneana
#10
Chengfu Yuan, Changdong Wang, Junjie Wang, Vikas Kumar, Firoz Anwar, Fangxiang Xiao, Gohar Mushtaq, Yufei Liu, Mohammad Amjad Kamal, Ding Yuan
Breast cancer is the second cause of cancer-related death among Women. Current therapies for breast cancer have adverse side-effects. Selenium (Se)-containing polysaccharides have multiple health benefits to humans. Pyracantha fortuneana (P. fortuneana) contains rich Se polysaccharides. We hypothesized that Se-containing polysaccharides from P. fortuneana possess anticancer activity on breast cancer via inhibiting growth and inducing apoptosis. This study aimed to assess the anticancer effect of Se-containing polysaccharides from P...
October 2, 2016: Nutrition Research
https://www.readbyqxmd.com/read/27865188/the-impact-of-digoxin-on-mortality-in-patients-with-chronic-systolic-heart-failure-a-propensity-matched-cohort-study
#11
May Al-Khateeb, Waqas T Qureshi, Raed Odeh, Amjad M Ahmed, Sherif Sakr, Radwa Elshawi, M Bassam Bdeir, Mouaz H Al-Mallah
BACKGROUND: Prior Studies showed mixed results in association of digoxin use with all-cause mortality (ACM). The aim of this analysis is to identify the impact of digoxin use on ACM in a contemporary heart failure (HF) cohort treated with guideline based therapy. METHODS: We included 2298 consecutive patients seen in an HF clinic between 2000 and 2015. Patients were considered to be a digoxin user if he/she received digoxin at any point during the enrollment period in the HF clinic...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27850623/985-high-flow-nasal-cannula-in-post-extubation-patients-a-meta-analysis
#12
Badr Aldawood, Amjad Al-Rajhi, Jason Shahin
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27842486/advances-and-implications-in-nanotechnology-for-lung-cancer-management
#13
Sana Sarkar, Khwaja Osama, Qazi Mohammad Sajid Jamal, Mohammad Amjad Kamal, Usman Sayeed, M Kalim A Khan, Mohd Haris Siddiqui, Salman Akhtar
Lung cancer is one of the most important chronic diseases in the field of respiratory medicine. Conventional treatment strategies for lung cancer include chemotherapy, surgery and radiation therapy. These current therapies lack specificity and are limited by undesirable toxicities in normal cells, as well as a high rate of recurrence.Nanotechnological intervention has greatly revolutionized the therapy of lung cancer by surmounting the current limitations in conventional therapies. Nanoparticles (NPs) achieve preferential accumulation in the tumor cells by employing two mechanisms: passive and active targeting...
November 14, 2016: Current Drug Metabolism
https://www.readbyqxmd.com/read/27837408/humanizing-glycosylation-pathways-in-eukaryotic-expression-systems
#14
REVIEW
Amjad Hayat Khan, Hadi Bayat, Masoumeh Rajabibazl, Suriana Sabri, Azam Rahimpour
Glycosylation represents the most widespread posttranslational modifications, found in a broad spectrum of natural and therapeutic recombinant proteins. It highly affects bioactivity, site-specificity, stability, solubility, immunogenicity, and serum half-life of glycoproteins. Numerous expression hosts including yeasts, insect cells, transgenic plants, and mammalian cells have been explored for synthesizing therapeutic glycoproteins. However, glycosylation profile of eukaryotic expression systems differs from human...
January 2017: World Journal of Microbiology & Biotechnology
https://www.readbyqxmd.com/read/27833921/management-of-patient-care-in-hemodialysis-while-focusing-on-cardiovascular-disease-events-and-the-atypical-role-of-hyper-and-or-hypotension-a-systematic-review
#15
REVIEW
Amjad Khan, Amer Hayat Khan, Azreen Syazril Adnan, Syed Azhar Syed Sulaiman, Siew Hua Gan, Irfanullah Khan
Background. Hemodialysis related hemodynamic instability is a major but an underestimated issue. Moreover, cardiovascular events are the leading cause of morbidity and mortality associated with blood pressure in hemodialysis patients. However, there have been many controversies regarding the role and management of hyper- and/or hypotension during hemodialysis that needs to be addressed. Objective. To critically review the available published data on the atypical role of hyper- and/or hypotension in cardiovascular associated morbidity and mortality in patients on hemodialysis and to understand the discrepancies in this context...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27830886/anomalous-left-brachiocephalic-vein-important-vascular-anomaly-concomitant-with-congenital-anomalies-and-heart-diseases
#16
Shahram Kahkouee, Makan Sadr, Elham Pedarzadeh, Sara Fardin, Ali Borhani, Saeid Gholami, Ghazaleh Amjad
BACKGROUND: Anomalous left brachiocephalic vein (ALBCV) is a rare and less known systemic venous anomaly. Infrequently, this vein takes an abnormal course and passes to the right behind or beneath the aortic arch to create the superior vena cava (SVC). Its incidence was reported much higher in patients with congenital heart disease (CHD) especially in conotruncal and aortic arch anomalies. It could be misdiagnosed with normal or abnormal mediastinal structures. It also could make complication during surgeries or invasive strategies...
November 10, 2016: Folia Morphologica (Warsz)
https://www.readbyqxmd.com/read/27830631/editorial-thematic-issue-association-of-cns-disorders-with-other-health-issues
#17
EDITORIAL
Mohammad Amjad Kamal
No abstract text is available yet for this article.
2016: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/27829738/adjunctive-aids-for-the-detection-of-oral-premalignancy
#18
REVIEW
D Charanya, L P Raghupathy, Amjad Fazeela Farzana, R Murugan, R Krishnaraj, G Kalarani
Early detection of cancer greatly decreases the morbidity and mortality rates and thereby increases the 5-year survival rates. In developing countries like India where the disease is highly prevalent focus is mainly on decreasing the mortality rates which can be easily achieved by detection at an asymptomatic stage. Visual examination has been the standard screening method for screening oral cancer through several decades, and it is well known that conventional visual examination is limited to subjective interpretation and cannot be easily achieved in certain anatomical sites...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/27817986/examining-the-context-and-helpfulness-of-family-companion-contributions-to-older-adults-primary-care-visits
#19
Jennifer L Wolff, Yue Guan, Cynthia M Boyd, Judith Vick, Halima Amjad, David L Roth, Laura N Gitlin, Debra L Roter
OBJECTIVE: Older adults commonly involve family (broadly defined) in their care. We examined communication behaviors of family companions during older adults' primary care visits, including whether these behaviors vary with respect to how older adults manage their health, preferences for involving family in medical decision-making, and ratings of companion helpfulness. METHODS: Analysis of audio-taped primary care visits of older patients who were accompanied by a family companion (n=30 dyads) and linked patient surveys...
October 25, 2016: Patient Education and Counseling
https://www.readbyqxmd.com/read/27812493/a-case-control-study-on-the-relationship-between-mycoplasma-genitalium-infection-in-women-with-normal-pregnancy-and-spontaneous-abortion-using-polymerase-chain-reaction
#20
Rashid Ramazanzadeh, Mazaher Khodabandehloo, Fariba Farhadifar, Samaneh Rouhi, Amjad Ahmadi, Shaho Menbari, Fariba Fallahi, Reza Mirnejad
OBJECTIVES: Mycoplasma genitalium infections are suggested as causes of a number of pathological outcomes in pregnant women. The aim of this study was to evaluate the frequency of M. genitalium infections among pregnant women and its association with spontaneous abortion. METHODS: In this case-control study we included 109 women with spontaneous abortion with a gestational age of 10-20 weeks (patients), and 109 women with normal pregnancy with a gestational age of 20-37 weeks (controls) in Sanandaj, Iran...
October 2016: Osong Public Health and Research Perspectives
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