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https://www.readbyqxmd.com/read/29791905/disparities-in-chronic-kidney-disease-prevalence-among-males-and-females-in-195-countries-analysis-of-the-global-burden-of-disease-2016-study
#1
Boris Bikbov, Norberto Perico, Giuseppe Remuzzi
BACKGROUND: Chronic kidney disease (CKD) imposes a substantial burden on health care systems. There are some especially vulnerable groups with a high CKD burden, one of which is women. We performed an analysis of gender disparities in the prevalence of all CKD stages and renal replacement therapy (defined as impaired kidney function [IKF]) in 195 countries. METHODS: We used estimates produced by the Global Burden of Disease (GBD) Study 2016 revision using a Bayesian-regression analytic tool, DisMoD-MR 2...
May 23, 2018: Nephron
https://www.readbyqxmd.com/read/29789986/optimal-equation-for-estimation-of-glomerular-filtration-rate-in-autosomal-dominant-polycystic-kidney-disease-influence-of-tolvaptan
#2
Tsuyoshi Yamaguchi, Eiji Higashihara, Takatsugu Okegawa, Isao Miyazaki, Kikuo Nutahara
BACKGROUND: The reliability of various equations for estimating the GFR in ADPKD patients and the influence of tolvaptan on the resulting estimates have not been examined when GFR is calculated on the basis of inulin clearance. METHODS: We obtained baseline and on-tolvaptan measured GFRs (mGFRs), calculated on the basis of inulin clearance, in 114 ADPKD, and these mGFRs were compared with eGFRs calculated according to four basic equations: the MDRD, CKD-EPI, and JSN-CKDI equations and the Cockcroft-Gault formula, as well as the influence of tolvaptan and of inclusion of cystatin C on accuracy of the results...
May 22, 2018: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/29788462/clinicopathological-predictors-for-progression-of-chronic-kidney-disease-in-nephrosclerosis-a-biopsy-based-cohort-study
#3
Masayuki Yamanouchi, Junichi Hoshino, Yoshifumi Ubara, Kenmei Takaichi, Keiichi Kinowaki, Takeshi Fujii, Kenichi Ohashi, Koki Mise, Tadashi Toyama, Akinori Hara, Miho Shimizu, Kengo Furuichi, Takashi Wada
Background: Biopsy-based studies on nephrosclerosis are lacking and the clinicopathological predictors for progression of chronic kidney disease (CKD) are not well established. Methods: We retrospectively assessed 401 patients with biopsy-proven nephrosclerosis in Japan. Progression of CKD was defined as new-onset end-stage renal disease, decrease of estimated glomerular filtration rate (eGFR) by  ≥50% or doubling of serum creatinine, and the sub-distribution hazard ratio (SHR) with 95% confidence interval (CI) for CKD progression was determined for various clinical and histological characteristics in competing risks analysis...
May 19, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29786454/serum-cystatin-c-as-an-early-predictor-of-acute-kidney-injury-in-preterm-neonates-with-respiratory-distress-syndrome
#4
Tarek Mohey El-Gammacy, Dina Mohamed Shinkar, Noha Refaat Mohamed, Amany Rasmy Al-Halag
Preterm neonates with respiratory distress syndrome (RDS) are at increased risk of acute kidney injury (AKI). Our study aimed at determining whether serum cystatin C (sCysC) on day 3 of life (D3) can early predict AKI in preterm neonates with RDS. This prospective study was conducted on 75 preterm neonates; 50 with RDS and 25 without RDS. On D3, sCysC, serum creatinine (sCr) and blood urea nitrogen (BUN) were measured and estimated glomerular filtration rate (eGFR) was calculated. sCr and BUN levels were measured again on days 5 and 7...
May 22, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29778943/prognostic-significance-of-serum-cystatin-c-in-acute-ischemic-stroke-patients-according-to-lipid-component-levels
#5
Zhengbao Zhu, Chongke Zhong, Tian Xu, Aili Wang, Yanbo Peng, Tan Xu, Hao Peng, Chung-Shiuan Chen, Jinchao Wang, Qunwei Li, Deqin Geng, Yingxian Sun, Yongqiu Li, Yonghong Zhang, Jiang He
BACKGROUND AND AIMS: Serum cystatin C (CysC) is associated with the risk of ischemic stroke and may predict cardiovascular events and death after ischemic stroke onset. However, the association between serum CysC and functional outcome in ischemic stroke patients remains unclear, and whether lipid component level influences the relationship between them has not been studied. METHODS: A total of 3348 ischemic patients from China Antihypertensive Trial in Acute Ischemic Stroke were included in the study...
May 17, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29775443/-b-type-natriuretic-peptide-as-a-marker-of-cardiac-dysfunction-in-children-with-chronic-kidney-disease
#6
Tomasz Drożdż, Przemko Kwinta, Zbigniew Kordon, Krystyna Sztefko, Andrzej Rudziński, Katarzyna Zachwieja, Monika Miklaszewska, Danuta Czarnecka, Dorota Drożdż
Left ventricular hypertrophy is the most common organ damage in children with chronic kidney disease (CKD). AIM: The aim of the study was to assess the usefulness of B-type natriuretic peptide (BNP) as a marker of heart injury in children with CKD. MATERIALS AND METHODS: We included 66 children (41 boys and 25 girls) aged 0.7 to 18.6 (median 11.6) years with CKD stage 1-5. The concentrations of urea, creatinine, cystatin C and BNP in blood serum were assessed, and the estimated glomerular filtration rate (eGFR) was calculated from the Schwartz and Filler formulas...
April 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29774462/combining-gfr-estimates-from-cystatin-c-and-creatinine-what-is-the-optimal-mix
#7
Emil den Bakker, Reinoud Gemke, Joanna A E van Wijk, Isabelle Hubeek, Birgit Stoffel-Wagner, Arend Bökenkamp
BACKGROUND: Combining estimated glomerular filtration rate (eGFR) equations based on creatinine and cystatin C has been shown to improve the accuracy of GFR estimation. This study aims to optimize this strategy for height-independent GFR estimation in children. METHODS: Retrospective study of 408 inulin clearance tests with simultaneous International Federation of Clinical Chemistry-calibrated measurements of creatinine, cystatin C, and urea in children (mean age 12...
May 17, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29771328/association-of-preoperative-plasma-fibrinogen-level-with-postoperative-bleeding-after-on-pump-coronary-bypass-surgery-does-plasma-fibrinogen-level-affect-the-amount-of-postoperative-bleeding
#8
Sameh Alagha, Murat Songur, Tugba Avci, Kerem Vural, Sadi Kaplan
OBJECTIVES: Our primary aim was to investigate the association between the preoperative concentration of plasma fibrinogen and the volume of postoperative bleeding. Our secondary aim was to identify whether there is a possible correlation between the patients' different characteristics and haemostatic laboratory variables and the postoperative amount of bleeding after on-pump coronary artery bypass grafting procedures. METHODS: A total of 550 adult patients undergoing isolated coronary artery bypass grafting on cardiopulmonary bypass in our hospital were enrolled and investigated retrospectively...
May 15, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29770263/evaluation-of-quantitative-and-qualitative-renal-outcome-following-nephron-sparing-surgery
#9
Gautam Ram Choudhary, Arup Kumar Mandal, Uttam Mete, Ravimohan Mavuduru, Anish Bhatacharia, Anupam Lal, Suresh Goyal
Purpose: Preservation of renal function after nephron-sparing surgery (NSS) is multifactorial and the impact of individual factors on it is still a debate. This prospective study investigates the impact of factors responsible for quantitative and functional outcome after NSS. Patients and Methods: Fifty-two patients of localized renal mass (≤7 cm) were included in the study. A contrast-enhanced computed tomography abdomen was performed for characterization of tumor...
2018: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/29768260/carboplatin-dosing-accuracy-by-estimation-of-glomerular-filtration-versus-creatinuria-in-cancer-patients
#10
Noiver Graciano Vera, Luis Pino Villarreal, Jenny Ureña Vargas
BACKGROUND: The glomerular filtration rate (GFR) is essential for calculating the dose and the monitoring of carboplatin. Although GFR measurement (mGFR) by external markers is ideal, in most cases these are not employed; the most used method is GFR estimation (eGFR) by formulae, hence the need to identify the formula with the best performance. METHODS: Patients admitted between 2011 and 2017 and diagnosed with ovarian, endometrial, lung, esophageal, or testicular cancer were assessed retrospectively...
May 16, 2018: Chemotherapy
https://www.readbyqxmd.com/read/29761990/-a-computer-tomography-assisted-method-for-the-automatic-detection-of-region-of-interest-in-dynamic-kidney-images
#11
Xueping Jing, Xiujuan Zheng, Shaoli Song, Kai Liu
Glomerular filtration rate (GFR), which can be estimated by Gates method with dynamic kidney single photon emission computed tomography (SPECT) imaging, is a key indicator of renal function. In this paper, an automatic computer tomography (CT)-assisted detection method of kidney region of interest (ROI) is proposed to achieve the objective and accurate GFR calculation. In this method, the CT coronal projection image and the enhanced SPECT synthetic image are firstly generated and registered together. Then, the kidney ROIs are delineated using a modified level set algorithm...
December 1, 2017: Sheng Wu Yi Xue Gong Cheng Xue za Zhi, Journal of Biomedical Engineering, Shengwu Yixue Gongchengxue Zazhi
https://www.readbyqxmd.com/read/29761689/percutaneous-nephrolithotomy-in-solitary-kidneys-effective-safe-and-improves-renal-functions
#12
Volkan Caglayan, Sedat Oner, Efe Onen, Sinan Avci, Murat Aydos, Metin Kilic, Murat Demirbas
BACKGROUND: To evaluate success and complication rates of endourological stone treatments and to evaluate effects of percutaneous nephrolithotomy (PCNL) on renal functions, in patients with solitary kidneys. METHODS: In our center, 3150 patients underwent PCNL between 2003 and 2017 and 142 patients underwent retrograd intrarenal surgery (RIRS) between 2013 and 2017. We retrospectively analysed the data of 82 patients with solitary kidney who underwent PCNL and of 8 patients with solitary kidney who underwent RIRS...
May 14, 2018: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/29759510/predicting-morbidity-after-robotic-partial-nephrectomy-the-effect-of-tumor-environment-and-patient-related-factors
#13
Zine-Eddine Khene, Benoit Peyronnet, Neil J Kocher, Haley Robyak, Corentin Robert, Benjamin Pradere, Emmanuel Oger, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Jay D Raman, Karim Bensalah
PURPOSE: To investigate the effect of tumor and nontumor related parameters on perioperative outcomes of robotic partial nephrectomy (RPN). PATIENTS AND METHODS: Patients who underwent RPN for a localized renal tumor at 2 institutions between June 2010 and November 2016 were reviewed. RENAL and Mayo adhesive probability (MAP) scores were calculated and information on comorbid conditions including ASA score, performance status, Charlson's comorbidity index (CCI), and history of cardiovascular disease was collected...
May 11, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29749989/first-report-on-the-percentiles-of-the-glomerular-filtration-rate-in-iranian-children-using-the-2009-schwartz-equations
#14
Peyman Roomizadeh, Alaleh Gheissari, Roya Kelishadi, Farhad Mahmoudi, Amin Abedini
The glomerular filtration rate (GFR) is widely considered the best overall index of renal function. The Schwartz equations are designed for measuring the GFR in children between 1 and 16 years of age. In the present study, we investigated the percentiles of the GFR in a general population of Iranian children with no known renal disease via the 2009 Schwartz equations (updated and combined equations). Between 2010 and 2011, we selected 687 children aged 7-16 years from the Iranian province of Isfahan. Blood samples were analyzed for blood urea nitrogen, creatinine, and cystatin C...
March 2018: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29744748/assessing-the-kidney-function-parameters-glomerular-filtration-rate-and-effective-renal-plasma-flow-with-dynamic-fdg-pet-mri-in-healthy-subjects
#15
Barbara K Geist, Pascal Baltzer, Barbara Fueger, Martina Hamboeck, Thomas Nakuz, Laszlo Papp, Sazan Rasul, Lalith Kumar Shiyam Sundar, Marcus Hacker, Anton Staudenherz
BACKGROUND: A method was developed to assess the kidney parameters glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) from 2-deoxy-2-[18 F]fluoro-D-glucose (FDG) concentration behavior in kidneys, measured with positron emission tomography (PET) scans. Twenty-four healthy adult subjects prospectively underwent dynamic simultaneous PET/magnetic resonance imaging (MRI) examination. Time activity curves (TACs) were obtained from the dynamic PET series, with the guidance of MR information...
May 9, 2018: EJNMMI Research
https://www.readbyqxmd.com/read/29738479/animal-and-plant-protein-intake-and-body-mass-index-and-waist-circumference-in-a-korean-elderly-population
#16
Ki-Byeong Park, Hyun Ah Park, Jae-Heon Kang, Kyoungwoo Kim, Young Gyu Cho, Jinyoung Jang
Controversy exists on whether animal and plant proteins influence obesity differently. The purpose of this study was to evaluate the association between total, animal, and plant protein intake with the body mass index (BMI), waist circumference (WC), and renal function in the Korean elderly. Study participants included Korean adults aged 60 years or older from the Korean National Health and Nutrition Examination Survey in 2013⁻2014. Height, weight, and waist circumference were measured and the body mass index was calculated...
May 8, 2018: Nutrients
https://www.readbyqxmd.com/read/29738041/association-between-estimated-glomerular-filtration-rate-and-sodium-excretion-in-urine-of-african-descendants-in-brazil-a-population-based-study
#17
Elisângela Milhomem Dos Santos, Dyego José de Araújo Brito, Ana Karina da Cunha Teixeira França, Joyce Santos Lages, Alcione Miranda Dos Santos, Natalino Salgado Filho
INTRODUCTION: Excessive salt intake is a risk factor for the development of chronic kidney disease (CKD). OBJECTIVE: To evaluate the association between estimated glomerular filtration rate (eGFR) and sodium excretion in urine samples of Brazilians of African ancestry. METHODS: Cross-sectional, population-based study of 1,211 Brazilians of African ancestry living in Alcântara City, Maranhão, Brazil. Demographic, nutritional, clinical, and laboratory data were analyzed...
May 7, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29723256/renal-protective-effect-of-antiplatelet-therapy-in-antiphospholipid-antibody-positive-lupus-nephritis-patients-without-antiphospholipid-syndrome
#18
Hironari Hanaoka, Harunobu Iida, Tomofumi Kiyokawa, Yukiko Takakuwa, Takahiro Okazaki, Hidehiro Yamada, Shoichi Ozaki, Kimito Kawahata
OBJECTIVE: We sought to evaluate the effect of antiplatelet therapy in addition to conventional immunosuppressive therapy for lupus nephritis (LN) patients positive for antiphospholipid antibodies (aPL) without definite antiphospholipid syndrome (APS). METHODS: Patients with biopsy-proven LN class III or IV were retrospectively evaluated. We selected patients positive for anticardiolipin antibody (aCL) or lupus anticoagulant (LA) who did not meet the criteria for a diagnosis of APS...
2018: PloS One
https://www.readbyqxmd.com/read/29698721/fixed-but-not-autoadjusting-positive-airway-pressure-attenuates-the-time-dependent-decline-in-glomerular-filtration-rate-in-patients-with-obstructive-sleep-apnea
#19
Oreste Marrone, Fabio Cibella, Jean-Louis Pépin, Ludger Grote, Johan Verbraecken, Tarja Saaresranta, John A Kvamme, Ozen K Basoglu, Carolina Lombardi, Walter T McNicholas, Jan Hedner, Maria R Bonsignore
BACKGROUND: The impact of treating obstructive sleep apnea (OSA) on renal function decline is controversial. Previous studies usually included small samples and did not consider specific effects of different continuous positive airway pressure (CPAP) modalities. The aim of this study was to evaluate the respective influence of fixed and auto-adjusting CPAP modes on estimated glomerular filtration rate (eGFR) in a large sample of patients derived from the prospective European Sleep Apnea Database (ESADA) cohort...
April 23, 2018: Chest
https://www.readbyqxmd.com/read/29697035/serum-n-terminal-pro-brain-natriuretic-peptide-level-is-associated-with-the-development-of-chronic-kidney-diseases-in-patients-with-type-2-diabetes
#20
Ryo Sawada, Yoshitaka Hashimoto, Takafumi Senmaru, Muhei Tanaka, Emi Ushigome, Masahiro Yamazaki, Michiaki Fukui
BACKGROUND AND OBJECTIVE: Previous studies revealed the association between serum N-terminal pro-brain natriuretic peptide (NT-proBNP) level and chronic kidney diseases (CKD) in general population. However, little is known about the association between serum NT-proBNP level and incident CKD in patients with type 2 diabetes. Thus, we investigated the impact of serum NT-proBNP level on incident CKD in patients with type 2 diabetes. METHOD: We enrolled 211 type 2 diabetic patients without CKD in this cohort study...
April 25, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
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