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glomerular filtration rate calculator

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https://www.readbyqxmd.com/read/28548236/renal-functional-outcomes-in-patients-undergoing-percutaneous-cryoablation-or-partial-nephrectomy-for-a-solitary-renal-mass
#1
Ross J Mason, Thomas D Atwell, Christine Lohse, Bimal Bhindi, Adam Weisbrod, Stephen A Boorjian, Bradley C Leibovich, Grant D Schmit, R Houston Thompson
OBJECTIVES: To compare renal functional changes after percutaneous cryoablation (CA) or partial nephrectomy (PN). PATIENTS AND METHODS: Patients who underwent CA or PN for a solitary renal mass at a single institution were identified (2003-2013). Estimated glomerular filtration rates (eGFR) were calculated at baseline, discharge, and 3 months follow-up using the Chronic Kidney Disease Epidemiology Collaboration equation. Changes in renal function were compared between groups using 1:1 propensity score (PS) matching, adjustment for PS quintile, and inverse probability weighting (IPW)...
May 26, 2017: BJU International
https://www.readbyqxmd.com/read/28546304/comparison-of-methods-of-estimating-creatinine-clearance-in-pediatric-patients
#2
Danielle Padgett, Andrew Ostrenga, Lindsey Lepard
PURPOSE: A retrospective study was conducted to compare various methods of measuring serum creatinine (SCr) values for use in pediatric renal function assessments, including a method aligned with a recently implemented national SCr testing standard. METHODS: Demographic, medication-use, and selected laboratory data were collected from the hospital records of a sample of pediatric patients (n = 91) who underwent 12- or 24-hour timed urine collection for determination of creatinine clearance (CLcr) over a 2-year period...
June 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28545627/impact-of-renal-function-on-survival-after-cardiac-resynchronization-therapy
#3
J Alvin Kpaeyeh, Laura Divoky, J Madison Hyer, David D Daly, Anbukarasi Maran, Ashley Waring, Michael R Gold
Chronic kidney disease (CKD) is associated with worse survival in patients with heart disease including those with implantable devices. Cardiac resynchronization therapy (CRT) can potentially improve renal function. To assess the relation between the change in renal function and survival with CRT, 238 patients undergoing initial CRT with defibrillator implantation between 2002 and 2011 were followed. The primary end point was all-cause mortality. The estimated glomerular filtration rate (eGFR), before implantation and 6 ± 3 months after CRT was calculated...
April 27, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28544308/use-of-a-new-end-stage-kidney-disease-risk-calculator-in-the-kidney-disease-improving-global-outcomes-guideline-to-evaluate-the-impact-of-different-living-kidney-donor-candidate-assessments
#4
Darren Lee, Momena Manzoor, Geoff Harley, John Whitlam, Natasha Cook, Suet-Wan Choy, Megan Sandiford, Charlotte Gibson, Lawrence P McMahon, Matthew A Roberts
AIM: The Kidney Disease Improving Global Outcomes (KDIGO) guideline recommends the incorporation of a new risk calculator that quantifies the end stage kidney disease (ESKD) risk based on a composite profile of risk factors in living kidney donor candidates (LKDCs). We compared the ESKD risk estimates in previously declined versus accepted LKDCs to evaluate the predictive capacity and potential impact of this tool. METHODS: Baseline 15-year and lifetime ESKD risk estimates without donation were calculated using the risk calculator for LKDCs assessed from two centres between 2007 and 2015...
May 20, 2017: Nephrology
https://www.readbyqxmd.com/read/28540888/assessment-of-renal-function-in-indian-patients-with-sickle-cell-disease
#5
Bhaskar V K S Lakkakula, Henu Kumar Verma, Mona Choubey, Suneeta Patra, Prafukka Kumar Khodiar, Pradeep Kumar Patra
Sickle cell disease (SCD) and its variants are genetic disorders resulting from the presence of a mutated form of hemoglobin. Renal disease is one of the most frequent complications, and kidney damage starts very early and progresses throughout life causing severe complications. The present study is aimed to analyze creatinine-based estimated glomerular filtration rate (eGFR) in 616 SCD patients (507 HbSS and 109 HbSB+), receiving medical care at outpatient wing of Sickle Cell Institute, Chhattisgarh. Glomerular filtration rate (GFR) estimated using the Modification of Diet in Renal Disease (MDRD), Cockcroft-Gault, chronic kidney disease epidemiology collaboration (CKD-EPI) (<17 years analyzed with Schwartz), and SCD specific Jamaica Sickle Cell Cohort Study (JSCCS)-GFR equations were compared...
May 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28540202/role-of-imaging-in-the-evaluation-of-renal-dysfunction-in-heart-failure-patients
#6
REVIEW
Dario Grande, Paola Terlizzese, Massimo Iacoviello
Heart failure and kidney disease share common pathophysiological pathways which can lead to mutual dysfunction, known as cardiorenal syndrome. In heart failure patients, renal impairment is related to hemodynamic and non-hemodynamic factors. Both decreased renal blood flow and renal venous congestion due to heart failure could lead to impaired renal function. Kidney disease and worsening renal function are independently associated with poor prognosis in heart failure patients, both in acute and chronic clinical settings...
May 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28537783/association-of-mild-to-moderate-reduction-in-glomerular-filtration-rate-with-subclinical-atherosclerosis-in-postmenopausal-women
#7
Florina Parv, Andrei Beceanu, Rodica Avram, Romulus Zorin Timar, Bogdan Timar, Florica Gadalean
BACKGROUND: Due to loss of hormonal protective effects, postmenopausal women have an increased cardiovascular (CV) risk. Chronic kidney disease (CKD) is a well-established risk factor for CV disease, but little is known whether mild-to-moderate kidney dysfunction is associated with atherosclerosis burden in the postmenopausal asymptomatic women. MATERIALS AND METHODS: Subclinical atherosclerosis was evaluated in 125 postmenopausal women with no clinical form of atherosclerosis, by carotid and femoral ultrasonography, ankle-brachial index (ABI), and flow-mediated dilation (FMD)...
May 24, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28537660/relation-between-blood-pressure-variability-and-early-renal-damage-in-hypertensive-patients
#8
L-H Yin, W-J Yan, Z-X Guo, F-Z Zhou, H-Y Zhang
OBJECTIVE: The objective of the present study was to observe the relation between blood pressure variability (BPV) and early renal damage in hypertensive patients. PATIENTS AND METHODS: A total of 118 hypertensive patients were consecutively selected. General parameters including sex, age, duration, and grade of hypertension, antihypertensive drugs taken, smoking status, blood sugar, blood lipid level, body mass index, indexes of 24-h ambulatory blood pressure monitoring and renal function including cystatin C (CysC), serum creatinine (SCr), angiotensin II (Ang II), microalbuminuria (mALb), and urine creatinine (UCr) were measured...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28536087/workflow-sensitivity-of-post-processing-methods-in-renal-dce-mri
#9
Erik Hanson, Eli Eikefjord, Jarle Rørvik, Erling Andersen, Arvid Lundervold, Erlend Hodneland
OBJECTIVE: Estimation of renal filtration using dynamic contrast-enhanced imaging (DCE-MRI) requires a series of analysis steps. The possible number of distinct post-processing chains is large and grows rapidly with increasing number of processing steps or options. In this study we introduce a framework for systematic evaluation of the post-processing chains. The framework is later used to highlight the workflow processing chain sensitivity towards accuracy in estimation of glomerular filtration rate (GFR)...
May 20, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28534209/the-renal-safety-and-efficacy-of-combined-gemcitabine-plus-cisplatin-and-gemcitabine-plus-carboplatin-chemotherapy-in-chinese-patients-with-a-solitary-kidney-after-nephroureterectomy
#10
Peng Sun, Cong Xue, Li-Ren Li, Cui Shao, Xin An, Ried Thomas, Wei Yang, Ying-Fei Deng, Wen-Qi Jiang, Yan-Xia Shi
PURPOSE: The renal safety of cisplatin-based chemotherapy has not been investigated in patients with urothelial carcinoma of the upper urinary tract (UUT-UC) who retain a solitary kidney after nephroureterectomy. This study aimed to assess and compare the renal safety and efficacy of gemcitabine-cisplatin (GP) and gemcitabine-carboplatin (GC) in these patients. METHODS: The medical records of patients diagnosed with urothelial carcinoma at the Sun Yat-Sen University Cancer Center between January 2005 and December 2015 were retrospectively reviewed...
May 22, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28530212/-measurements-of-vancomycin-concentrations-in-the-blood-a-method-of-personalization-the-antibiotic-therapy-in-patients-with-chronic-kidney-disease
#11
Joanna Pondel, Piotr Krajewski, Natalia Królikowska, Aleksandra Tobiasz, Hanna Augustyniak-Bartosik, Magdalena Hurkacz
Therapeutic Drug Monitoring is a recognized method of personalizing treatment, having particular application in patients with chronic kidney disease who have frequent infections, requiring administration of vancomycin. International guidelines indicate the need to adjust the dose of the drug to the state of renal function. The recommended therapeutic ranges of minimum and maximum levels should be achieved in order to increase the effectiveness and safety of treatment. AIM: The aim of this study was to evaluate the usefulness of measuring the concentration of vancomycin in patients with chronic kidney disease due to bacterial infection...
April 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28523527/impact-of-estimated-glomerular-filtration-rate-on-diabetic-macular-edema
#12
Shreyas Temkar, Nishanthini Karuppaiah, Brijesh Takkar, Dipankar Bhowmik, Manjari Tripathi, Sivasubramanian Ramakrishnan, Yog Raj Sharma, Rajpal Vohra, Rohan Chawla, Pradeep Venkatesh
PURPOSE: Diabetic macular edema (DME) is a major cause of visual impairment in patients with diabetes and is influenced by various systemic factors. This study evaluates the effect of renal status on DME using estimated glomerular filtration rate (eGFR) as a study marker. METHODS: This was a prospective observational cross-sectional study. One hundred and ninety-five patients of diabetic retinopathy (DR) were included. Group 1 had patients of DR without DME (n = 100), and group 2 had patients of DR with DME (n = 95)...
May 18, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28523356/evaluation-of-height-dependent-and-height-independent-methods-of-estimating-baseline-serum-creatinine-in-critically-ill-children
#13
Erin Hessey, Rami Ali, Marc Dorais, Geneviève Morissette, Michael Pizzi, Nikki Rink, Philippe Jouvet, Jacques Lacroix, Véronique Phan, Michael Zappitelli
BACKGROUND: Baseline serum creatinine (bSCr) is required for diagnosing acute kidney injury (AKI). In children, bSCr is commonly defined as the lowest measurement within 3 months of admission. Measured values are often missing and estimating bSCr using height-based glomerular filtration rate (GFR) equations is problematic when height is unavailable. METHODS: This is a retrospective cohort study including 538 children admitted to the intensive care unit (ICU) between 2003 and 2005 at two centers in Canada, with measured bSCr, height, and ICU-SCr values...
May 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28514315/role-of-cystatin-c-and-glomerular-filtration-rate-in-diagnosis-of-kidney-impairment-in-hepatic-cirrhosis-patients
#14
Dong Wang, Jia-Fu Feng, An-Qun Wang, Yu-Wei Yang, Yun-Shuang Liu
Hepatic cirrhosis is often accompanied by functional kidney impairment, which may be reversed if early treatment is promptly administered. This study aimed to investigate the role of Cystatin C and Cystatin C estimated glomerular filtration rate in the diagnosis of kidney impairment in patients with hepatic cirrhosis.Four hundred sixty five patients with hepatic cirrhosis were recruited. Serum creatinine and Cystatin C were determined, and their estimated glomerular filtration rates were calculated.The area under the receiver-operating characteristic curve (area under curve [AUC]) of Cystatin C and Cystatin C estimated glomerular filtration rate was significantly larger than that of serum creatinine and serum creatinine estimated glomerular filtration rate, respectively (P = ...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28513510/factors-associated-with-blood-pressure-control-in-predialysis-chronic-kidney-disease-patients-short-term-experience-from-a-single-center-in-southern-nigeria
#15
E I Okaka, O E Ojeh-Oziegbe, E I Unuigbe
BACKGROUND: Hypertension is a leading cause of kidney disease worldwide, and chronic kidney disease (CKD) is a known cause of secondary hypertension. Blood pressure (BP) control is a main-stay in the management of CKD because it retards the progression of established CKD. AIM: To determine BP control and its associated factors in predialysis CKD patients in a tertiary hospital setting. METHODOLOGY: CKD patients who attended the renal outpatient clinic during the period from December 2013 to June 2014 were recruited into the study...
May 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28508095/estimation-of-glomerular-filtration-rate-in-cancer-patients-with-abnormal-body-composition-and-relation-with-carboplatin-toxicity
#16
M Bretagne, A Jouinot, J P Durand, O Huillard, P Boudou Rouquette, C Tlemsani, J Arrondeau, G Sarfati, F Goldwasser, J Alexandre
PURPOSE: Carboplatin clearance is correlated with glomerular filtration rate (GFR) and usually estimated with creatinine clearance using Cockcroft-Gault (CG) formula. Because plasma creatinine level is highly correlated with muscle mass, we hypothesized that an abnormal body composition with a low lean body mass (LBM) percentage [(LBM/weight) × 100] may result in inadequate carboplatin dosing. Serum cystatin C is an alternative marker of GFR, not affected by muscle mass. We aimed to investigate the influence of total LBM and LBM percentage on GFR calculation, using creatinine (CrCl) or cystatin C (GFRcysC-creat) in cancer patients...
May 15, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28503237/modified-c-index-novel-predictor-of-postoperative-renal-functional-loss-of-laparoscopic-partial-nephrectomy
#17
Hiroki Ito, Kazuhide Makiyama, Takashi Kawahara, Kimito Osaka, Koji Izumi, Yumiko Yokomizo, Noboru Nakaigawa, Masahiro Yao
INTRODUCTION: We aimed to develop a scoring system to quantify the distance between the renal hilum and renal tumour, termed the modified C index (m-CI), and to predict renal functional loss (RFL) following laparoscopic partial nephrectomy (LPN). METHODS: The m-CI was measured by using computed tomography in 113 patients who underwent LPN between May 2003 and June 2014. The RFL following LPN was calculated by examining the estimated glomerular filtration rate (eGFR) and radioisotope renography one year postoperatively...
May 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28502322/high-prevalence-of-elevated-molybdenum-levels-in-pediatric-ckd-patients-a-cross-sectional-and-longitudinal-study%C3%A2
#18
Guido Yang, Vladimir Belostotsky, Marta Kobrzynski, Shih-Han S Huang, Liju Yang
AIMS: Many of the secondary effects of high levels of molybdenum (Mo) overlap with symptoms commonly seen in pediatric patients with chronic kidney disease (CKD). We measured plasma Mo levels and examined the relationship between Mo levels and kidney function. MATERIALS AND METHODS: The study was carried out at the London Health Sciences Centre in London, Ontario, Canada with 36 children and adolescents 4 - 18 years of age with CKD. There were 1 - 6 trace element measurements (Mo and copper (Cu)) per patient...
May 15, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28500363/diffusion-weighted-imaging-of-the-kidneys-in-haemolytic-uraemic-syndrome
#19
Jochen Herrmann, Ulrich Wenzel, Stephanie Galler, Bjoern P Schoennagel, Jasmin D Busch, Magdalini Tozakidou, Kay U Petersen, Michaela Joekel, Peter Bannas, Jin Yamamura, Michael Groth, Gerhard Adam, Christian R Habermann
OBJECTIVES: To evaluate the kidneys of patients with haemolytic uraemic syndrome (HUS) using diffusion-weighted imaging (DWI) and Doppler ultrasound (US) compared with healthy controls. MATERIALS AND METHODS: Fifteen patients (mean age 33.3 years; three male; 12 female) with diarrhoea-positive HUS and 15 healthy volunteers were prospectively evaluated with DWI and Doppler US. A total apparent diffusion coefficient (ADCTOT), and ADCs predominantly reflecting microperfusion (ADCLOW) and diffusion (ADCHIGH) were calculated...
May 12, 2017: European Radiology
https://www.readbyqxmd.com/read/28499044/determinants-of-decline-of-renal-function-in-treated-hypertensive-patients-the-campania-salute-network
#20
Costantino Mancusi, Raffaele Izzo, Giovanni de Simone, Maria Viviana Carlino, Grazia Canciello, Eugenio Stabile, Nicola de Luca, Bruno Trimarco, Maria Angela Losi
Background.: Hypertension is a leading cause of chronic kidney disease (CKD) and a decrease in glomerular filtration rate (GFR) is associated with a higher prevalence of hypertension and an increased proportion of suboptimal blood pressure (BP) control. Methods.: To investigate characteristics associated with GFR decline, we selected 4539 hypertensive patients from the Campania Salute Network (mean age 53 ± 11 years) with at least 3 years of follow-up (FU) and no more than Stage III CKD...
May 12, 2017: Nephrology, Dialysis, Transplantation
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