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Barbara Röper, Danielle Kaisig, Florian Auer, Ertan Mergen, Michael Molls
BACKGROUND AND PURPOSE: In radiotherapy of the breast following breast-conserving surgery, the adverse reaction predominantly found is confined to the skin. After phase II studies, Thêta-Cream, containing CM Glucan, Hydroxyprolisilan C und Matrixyl as active substances, was said to have prophylactic properties of preventing acute radiation side effects in skin tissue. In a prospective randomized study, Thêta-cream was compared with standard skin care using Bepanthol lotion. PATIENTS AND METHODS: 20 breast cancer patients were randomly assigned to use Thêta-Cream or Bepanthol lotion during radiotherapy...
May 2004: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
Kathrin Biro, Diamant Thaçi, Falk R Ochsendorf, Roland Kaufmann, Wolf-Henning Boehncke
Dexpanthenol is popular in treating various dermatoses and in skin care, but few controlled clinical trials have been performed. We investigated the efficacy of dexpanthenol in skin protection against irritation in a randomized, prospective, double-blind, placebo-controlled study. 25 healthy volunteers (age 18-45 years) were treated for the inner aspect of both forearms with either Bepanthol Handbalsam containing 5% dexpanthenol or placebo x2 daily for 26 days. From day 15-22, sodium lauryl sulfate (SLS) 2% was applied to these areas x2 daily...
August 2003: Contact Dermatitis
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