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Sodium nitrite

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https://www.readbyqxmd.com/read/28199889/polyphosphate-and-myofibrillar-protein-extract-promote-transglutaminase-mediated-enhancements-of-rheological-and-textural-properties-of-pse-pork-meat-batters
#1
Tomasz Lesiow, Gregg K Rentfrow, Youling L Xiong
The objective of this study was to improve the rheological (storage modulus G'; phase angle δ) and textural (hardness; breaking force) properties of nitrite-cured sausage batters prepared from pale, soft, exudative (PSE) pork with microbial transglutaminase (TG) using isolated myofibrillar protein (MP) or MP extracted by sodium tripolyphosphate (TPP) as substrates. While TG alone significantly enhanced G', δ and hardness, its combination with TPP was more pronounced as these product quality parameters were increased to the level equal to that of the counterpart batter made from normal (red, firm, non-exudative, RFN) pork...
February 5, 2017: Meat Science
https://www.readbyqxmd.com/read/28196859/dietary-nitrite-reverses-features-of-postmenopausal-metabolic-syndrome-induced-by-high-fat-diet-and-ovariectomy-in-mice
#2
Kazuo Ohtake, Nobuyuki Ehara, Hiroshige Chiba, Genya Nakano, Kunihiro Sonoda, Junta Ito, Hiroyuki Uchida, Jun Kobayashi
Menopausal women are at greater risk of developing metabolic syndrome with reduced endothelial nitric oxide synthase (eNOS) activity. Hormone replacement therapy increases eNOS activity and normalizes some characteristics of metabolic syndrome. We hypothesized that nitric oxide (NO) supplementation should have a therapeutic effect in this syndrome. We examined the effect of dietary nitrite on mice model with postmenopausal metabolic syndrome induced by ovariectomy (OVX) with high fat diet (HF). C57BL/6 female mice were divided into five groups, sham+normal fat diet (NF), sham+ HF, OVX+HF without or with sodium nitrite (50mg and 150mg/L) in drinking water...
February 14, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28195581/cultivation-and-characterization-of-candidatus-nitrosocosmicus-exaquare-an-ammonia-oxidizing-archaeon-from-a-municipal-wastewater-treatment-system
#3
Laura A Sauder, Mads Albertsen, Katja Engel, Jasmin Schwarz, Per H Nielsen, Michael Wagner, Josh D Neufeld
Thaumarchaeota have been detected in several industrial and municipal wastewater treatment plants (WWTPs), despite the fact that ammonia-oxidizing archaea (AOA) are thought to be adapted to low ammonia environments. However, the activity, physiology and metabolism of WWTP-associated AOA remain poorly understood. We report the cultivation and complete genome sequence of Candidatus Nitrosocosmicus exaquare, a novel AOA representative from a municipal WWTP in Guelph, Ontario (Canada). In enrichment culture, Ca...
February 14, 2017: ISME Journal
https://www.readbyqxmd.com/read/28193415/changes-of-sodium-nitrate-nitrite-and-n-nitrosodiethylamine-during-in-vitro-human-digestion
#4
Hyeong Sang Kim, Sun Jin Hur
This study aimed to determine the changes in sodium nitrate, sodium nitrite, and N-nitrosodiethylamine (NDEA) during in vitro human digestion, and the effect of enterobacteria on the changes in these compounds. The concentrations of nitrate, nitrite, and NDEA were significantly reduced from 150, 150, and 1ppm to 42.8, 63.2, and 0.85ppm, respectively, during in vitro human digestion (p<0.05). The enterobacteria Escherichia coli and Lactobacillus casei reduced the amount of these compounds present during in vitro human digestion...
June 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28187467/protective-effects-of-ellagic-acid-on-cardiovascular-injuries-caused-by-hypertension-in-rats
#5
Juliana Bahia Reis Jordão, Hellen Karine Paes Porto, Flávio Marques Lopes, Aline Carvalho Batista, Matheus Lavorenti Rocha
Ellagic acid is described as having antioxidant and antiproliferative properties. Hence, it was hypothesized that ellagic acid could improve cardiovascular damage caused by hypertension. In this work, hypertension was induced in rats with Nω-Nitro-L-arginine methyl ester hydrochloride (60 mg/kg/day in drinking water) for 6 weeks. Ellagic acid was coadministered (10 or 30 mg/kg/day by gavage) between the second and sixth week. Blood pressure was recorded every week by tail-cuff plethysmography. After 6 weeks, the rats were sacrificed, the hearts and kidneys were weighed, and blood was collected...
February 10, 2017: Planta Medica
https://www.readbyqxmd.com/read/28177694/is-there-a-role-of-inos-activation-in-the-delayed-antiarrhythmic-effect-of-sodium-nitrite
#6
Vivien Demeter-Haludka, László Juhász, Mária Kovács, János Gardi, Ágnes Végh
This study aimed to examine whether inducible nitric oxide synthase (iNOS) plays a role in the delayed antiarrhythmic effect of sodium nitrite. Twenty-one dogs were infused intravenously with sodium nitrite (0.2 µmol/kg/min) for 20 min, either in the absence (<i>n</i>=12) or in the presence of the iNOS inhibitor S-(2-aminoethyl)-isothiourea (AEST; total dose: 2.0 mg/kg;<i> i.v.</i>, <i>n</i>=9). Control dogs (<i>n</i>=12) were given saline. Twenty-four hours later, all the dogs were subjected to a 25 min period occlusion of the left anterior descending (LAD) coronary artery, followed by rapid reperfusion...
November 24, 2016: Canadian Journal of Physiology and Pharmacology
https://www.readbyqxmd.com/read/28163087/l-%C3%AE-n-methylamino-l-alanine-bmaa-nitrosation-generates-a-cytotoxic-dna-damaging-alkylating-agent-an-unexplored-mechanism-for-neurodegenerative-disease
#7
G Potjewyd, P J Day, S Shangula, G P Margison, A C Povey
BACKGROUND: L-β-N-methylamino-L-alanine (BMAA) is a non-proteinic amino acid, that is neurotoxic in vitro and in animals, and is implicated in the causation of amyotrophic lateral sclerosis and parkinsonism-dementia complex (ALS-PDC) on Guam. Given that natural amino acids can be N-nitrosated to form toxic alkylating agents and the structural similarity of BMAA to other amino acids, our hypothesis was that N-nitrosation of BMAA might result in a toxic alkylating agent, providing a novel mechanistic hypothesis for BMAA action...
February 2, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28157581/survival-of-listeria-monocytogenes-with-different-antibiotic-resistance-patterns-to-food-associated-stresses
#8
Norton Komora, Carolina Bruschi, Rui Magalhães, Vânia Ferreira, Paula Teixeira
The ongoing rise of antibiotic resistant microbial pathogens has become one of the major public health threats worldwide. Despite all the effort and actions taken so far, a proliferation of antibiotic resistant (AR) and multi-antibiotic resistant (MAR) strains is still observed, including in foodborne pathogens. This trend has been also noted recently for isolates of Listeria monocytogenes, a species that, although remaining largely sensitive to clinically relevant antimicrobials, has been reported to develop increased tolerance to antibiotics, particularly in isolates recovered from the food-chain...
January 24, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28116921/effect-of-silver-nanoparticles-synthesized-by-gamma-radiation-on-the-cytotoxicity-of-doxorubicin-in-human-cancer-cell-lines-and-experimental-animals
#9
H H Mansour, M Eid, M B El-Arnaouty
Silver nanoparticles (AgNPs)embedded poly ( N-vinylpyrrolidone/dextran) hydrogels were prepared by gamma radiation. Highly stable and uniformly distributed AgNPs have been obtained within hydrogel networks as nanoreactors via in situ reduction of silver nitrate using sodium borohydride as reducing agent. The formation of AgNPs has been confirmed by Fourier transform infrared spectroscopy. The ultraviolet-visible spectroscopy measurements show a distinct characteristic absorption peaks around 420 nm, indicating the formation of AgNPs...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28111973/efficacy-of-crocin-and-safranal-as-protective-agents-against-genotoxic-stress-induced-by-gamma-radiation-urethane-and-procarbazine-in-mice
#10
A Koul, S K Abraham
Crocin (CRO) and safranal (SAF) are bioactive constituents of saffron (dried stigma of Crocus sativus flower), an expensive spice with medicinal properties. Aqueous extract of saffron is known for its antigenotoxic effect against environmental genotoxins/carcinogens. However, there is need to identify saffron constituents responsible for this antigenotoxic effect. The aim of our investigation was to ascertain the role of CRO and SAF as inhibitors of in vivo genotoxic stress. For this purpose, Swiss albino mice were pretreated with CRO (50-mg/kg body weight (bw))/SAF (0...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28105834/in-line-acidification-for-potentiometric-sensing-of-nitrite-in-natural-waters
#11
Nadezda Pankratova, Maria Cuartero, Thomas Cherubini, Gaston A Crespo, Eric Bakker
We report on a novel approach for in-line sample acidification that results in a significant improvement in the limit of detection of potentiometric anion-selective electrodes aiming at determining nutrients in natural waters. The working principle of the developed acidification module relies on the cation-exchange process between the sample and an ion-exchange Donnan exclusion membrane in its protonated form. The resulting in-line acidification of natural waters with millimolar sodium chloride level (freshwater, drinking water, and aquarium water, as well as dechloridized seawater) decreases the pH down to ∼5...
January 3, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28095321/cellulose-to-depolymerize%C3%A2-or-not-to
#12
REVIEW
Sergiu Coseri
Oxidation of the primary OH groups in cellulose is a pivotal reaction both at lab and industrial scale, leading to the value-added products, i.e. oxidized cellulose which have tremendous applications in medicine, pharmacy and hi-tech industry. Moreover, the introduction of carboxyl moieties creates prerequisites for further cellulose functionalization through covalent attachment or electrostatic interactions, being an essential achievement designed to boost the area of cellulose-based nanomaterials fabrication...
January 15, 2017: Biotechnology Advances
https://www.readbyqxmd.com/read/28089828/nitrite-increases-glucose-stimulated-insulin-secretion-and-islet-insulin-content-in-obese-type-2-diabetic-male-rats
#13
Sevda Gheibi, Fatemeh Bakhtiarzadeh, Sajad Jeddi, Khadijeh Farrokhfall, Homeira Zardooz, Asghar Ghasemi
PURPOSE: Reduced bioavailability of nitric oxide (NO) is associated with pathogenesis of type 2 diabetes. Nitrite can act as a substrate for generation of systemic NO. The aim of this study was to examine the effects of nitrite administration on glucose-stimulated insulin secretion (GSIS) and islet insulin content in obese type 2 diabetic rats. METHODS: Male rats were divided into 4 groups: Control, control + nitrite, diabetes, and diabetes + nitrite. Sodium nitrite (50 mg/L in drinking water) was administered for 8 weeks...
January 9, 2017: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28068841/listeria-monocytogenes-behaviour-and-quality-attributes-during-sausage-storage-affected-by-sodium-nitrite-sodium-lactate-and-thyme-essential-oil
#14
Carla María Blanco-Lizarazo, Rubén Betancourt-Cortés, Angélica Lombana, Katerine Carrillo-Castro, Indira Sotelo-Díaz
The effects of the addition of nitrite at 200 ppm (N), sodium lactate 1.5% (L) and thyme essential oil at 100 ppm (T1) on Listeria monocytogenes behaviour and ATPase activity inhibition were evaluated, as well as lipid oxidation through the quantification of malonaldehydes, in sausage stored at 8 ℃ for 41 days and at 30 ℃ for 14 days. The changes in the colour profile were performed during storage time at 8 ℃. Quantitative descriptive sensory analyses were performed after two days at 4 ℃...
January 1, 2017: Food Science and Technology International, Ciencia y Tecnología de Los Alimentos Internacional
https://www.readbyqxmd.com/read/28041825/sodium-nitrite-and-sodium-thiosulfate-are-effective-against-acute-cyanide-poisoning-when-administered-by-intramuscular-injection
#15
Vikhyat S Bebarta, Matthew Brittain, Adriano Chan, Norma Garrett, David Yoon, Tanya Burney, David Mukai, Michael Babin, Renate B Pilz, Sari B Mahon, Matthew Brenner, Gerry R Boss
STUDY OBJECTIVE: The 2 antidotes for acute cyanide poisoning in the United States must be administered by intravenous injection. In the out-of-hospital setting, intravenous injection is not practical, particularly for mass casualties, and intramuscular injection would be preferred. The purpose of this study is to determine whether sodium nitrite and sodium thiosulfate are effective cyanide antidotes when administered by intramuscular injection. METHODS: We used a randomized, nonblinded, parallel-group study design in 3 mammalian models: cyanide gas inhalation in mice, with treatment postexposure; intravenous sodium cyanide infusion in rabbits, with severe hypotension as the trigger for treatment; and intravenous potassium cyanide infusion in pigs, with apnea as the trigger for treatment...
December 29, 2016: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28027835/toward-nitrogen-14-nuclear-quadrupole-resonance-imaging-by-nutation-experiments-performed-with-a-radio-frequency-field-gradient
#16
Sarra Aissani, Laouès Guendouz, Pierre-Louis Marande, Daniel Canet
Until now, NQR imaging has been considered mainly in the case of Chlorine-35. This is a spin 3/2 resonating at relatively high frequency (around 30MHz) thus affording a favorable sensitivity. Conversely, Nitrogen-14 (spin 1) NQR is much less sensitive because its resonances frequencies are below 6MHz. In contrast to already existing methodologies for object localization by (14)N NQR, we present here a new, more straightforward, approach and the principles of space dependent (14)N Quadrupole Resonance are laid down...
December 16, 2016: Solid State Nuclear Magnetic Resonance
https://www.readbyqxmd.com/read/28017995/effect-of-partial-substitution-of-nacl-by-kcl-on-physicochemical-properties-biogenic-amines-and-n-nitrosamines-during-ripening-and-storage-of-dry-cured-bacon
#17
Feng Li, Hong Zhuang, Weiwei Qiao, Jianhao Zhang, Yongli Wang
Effects of three salting treatments (Formulation II: 80 % NaCl + 20 % KCl; Formulation III: 60 % NaCl + 40 % KCl and Formulation IV: 40 % NaCl + 60 % KCl) on physicochemical properties, residual nitrite, N-nitrosamines and biogenic amines were compared with those of control bacons (Formulation I: 100 % NaCl) during processing and storage. Results showed that there were no significant differences among treatments for moisture, pH, and total volatile basic nitrogen (TVBN) content in dry-cured bacons during processing...
October 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28017872/nitrite-derived-nitric-oxide-reduces-hypoxia-inducible-factor-1%C3%AE-mediated-extracellular-vesicle-production-by-endothelial-cells
#18
Nicholas Burnley-Hall, Gareth Willis, Jessica Davis, D Aled Rees, Philip E James
INTRODUCTION: Extracellular vesicles (EVs) are small, spherical particles enclosed by a phospholipid bilayer (∼30-1000 nm) released from multiple cell types, and have been shown to have pathophysiological roles in a plethora of disease states. The transcription factor hypoxia-inducible factor-1 (HIF-1) allows for adaptation of cellular physiology in hypoxia and may permit the enhanced release of EVs under such conditions. Nitric oxide (NO) plays a pivotal role in vascular homeostasis, and can modulate the cellular response to hypoxia by preventing HIF-1 accumulation...
December 23, 2016: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/28010842/ultra-sensitive-hplc-photochemical-reaction-luminol-chemiluminescence-method-for-the-measurement-of-secondary-amines-after-nitrosation
#19
Hitoshi Kodamatani, Yoshimi Iwaya, Makoto Saga, Keiitsu Saito, Takahiro Fujioka, Shigeo Yamazaki, Ryo Kanzaki, Takashi Tomiyasu
A novel method for the determination of secondary amines at the nanomolar level was developed. The method is based on the nitrosation reaction of secondary amines, with the generated N-nitrosamines being measured using an HPLC separation, photochemical reaction, and chemiluminescence detection system. The efficient nitrosation of secondary amines was performed using sodium nitrite (200 mM) and acetic acid (0.8 M) at 80 °C over 60 min. Although compounds bearing OH and SH functional groups also underwent the nitrosation reaction, the sensitivity of these compounds was 1000 times lower than that of the secondary amines...
February 1, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28000380/quercetin-inhibits-sodium-nitrite-induced-inflammation-and-apoptosis-in-different-rats-organs-by-suppressing-bax-hif1-%C3%AE-tgf-%C3%AE-smad-2-and-akt-pathways
#20
Nouf Mohamed Al-Rasheed, Laila Mohamed Fadda, Hala A Attia, Hanaa Mahmoud Ali, Nawal Mohamed Al-Rasheed
The objective of this work is to study the protective effects of Quercetin against sodium nitrite-induced hypoxia on liver, lung, kidney and cardiac tissues, also to explore novel mechanism of this compound. Male albino rats were injected with sodium nitrite (75 mg/kg). Quercetin (200 mg kg(-1) ,- i.p.) was administrated 24 and 1 h respectively prior to sodium nitrite intoxication, hypoxia significantly decreased hemoglobin concentration, while increased expressions of HIF, Bax, Smad-2, TGF-β, and AKT...
December 21, 2016: Journal of Biochemical and Molecular Toxicology
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