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Sodium nitrite

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https://www.readbyqxmd.com/read/28416347/blood-collection-vials-and-clinically-used-intravenous-fluids-contain-significant-amounts-of-nitrite
#1
Luis E F Almeida, Sayuri Kamimura, Margaret Y Nettleton, Celia M de Souza Batista, Elizabeth Walek, Alfia Khaibullina, Li Wang, Zenaide M N Quezado
The biology of the inorganic anion nitrite is linked to nitric oxide (NO) as nitrite can be reduced to NO and mediate its biological activities. Thus, studies of nitrite biology require sensitive and selective chemical assays. The acetic and ascorbic acids method is selective for nitrite and measures it in biological matrices. However, one of the pitfalls of nitrite measurements is its ubiquitous presence in sample collection tubes. Here, we showed high levels of nitrite in collection tubes containing EDTA, sodium citrate or sodium heparin and smaller amounts in tubes containing lithium heparin or serum clot activator...
April 14, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28402313/effects-of-carbon-sources-cod-no2-n-ratios-and-temperature-on-the-nitrogen-removal-performance-of-the-simultaneous-partial-nitrification-anammox-and-denitrification-snad-biofilm
#2
Zhaoming Zheng, Yun Li, Jun Li, Yanzhuo Zhang, Wei Bian, Jia Wei, Baihang Zhao, Jingyue Yang
The aim of the present work was to evaluate the effects of carbon sources and chemical oxygen demand (COD)/NO2(-)-N ratios on the anammox-denitrification coupling process of the simultaneous partial nitrification, anammox and denitrification (SNAD) biofilm. Also, the anammox activities of the SNAD biofilm were investigated under different temperature. Kaldnes rings taken from the SNAD biofilm reactor were operated in batch tests to determine the nitrogen removal rates. As a result, with the carbon source of sodium acetate, the appropriate COD/NO2(-)-N ratios for the anammox-denitrification coupling process were 1 and 2...
April 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28389351/enhancing-colour-and-oxidative-stabilities-of-reduced-nitrites-turkey-meat-sausages-during-refrigerated-storage-using-fucoxanthin-purified-from-the-tunisian-seaweed-cystoseira-barbata
#3
Sabrine Sellimi, Ghada Ksouda, Abdelkarim Ben Slima, Rim Nasri, Marguerite Rinaudo, Moncef Nasri, Mohamed Hajji
The present study investigated the angiotensin-I converting enzyme (ACE) inhibitory activity and the antioxidant properties, in vitro and in cured meat sausages containing reduced levels of sodium nitrites, of fucoxanthin purified from the Tunisian brown seaweed Cystoseira barbata (CBFX). Results revealed that CBFX exhibited great scavenging activities against DPPH free radicals (EC50 = 136 μg/ml), peroxyl radicals in the linoleate-β-carotene system (EC50 = 43 μg/ml) and hydroxyl radicals generated by Fenton reaction (DNA nicking assay)...
April 4, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28388524/a-sensitive-method-for-the-determination-of-sulfonamides-in-seawater-samples-by-solid-phase-extraction-and-uv-visible-spectrophotometry
#4
Sophia Ait Errayess, Abdellatif Ait Lahcen, Laila Idrissi, Caterina Marcoaldi, Salvatore Chiavarini, Aziz Amine
The authors have developed a sensitive spectrophotometric method for determination of sulfonamide derivatives such as sulfanilamide (SAA), sulfadiazine (SDZ), sulfacetamide (SCT) sulfamethoxazole (SMX), sulfamerazine (SMR), sulfadimethoxine (SDX), sulfamethiazole (SMT) and Sulfathiazole (STZ). This method is based on the Bratton-Marshall reaction, which involves the diazotization of sulfonamides with sodium nitrite under acidic conditions, followed by coupling with N-(1-naphtyl) ethylenediamine dihydrochloride (NED) to form a pink colored compound...
March 28, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28384248/acute-oral-dose-of-sodium-nitrite-induces-redox-imbalance-dna-damage-metabolic-and-histological-changes-in-rat-intestine
#5
Fariheen Aisha Ansari, Shaikh Nisar Ali, Hussain Arif, Aijaz Ahmed Khan, Riaz Mahmood
Industrialization and unchecked use of nitrate/nitrite salts for various purposes has increased human exposure to high levels of sodium nitrite (NaNO2) which can act as a pro-oxidant and pro-carcinogen. Oral exposure makes the gastrointestinal tract particularly susceptible to nitrite toxicity. In this work, the effect of administration of a single acute oral dose of NaNO2 on rat intestine was studied. Animals were randomly divided into four groups and given single doses of 20, 40, 60 and 75 mg NaNO2/kg body weight...
2017: PloS One
https://www.readbyqxmd.com/read/28383258/environmental-conditions-influencing-sorption-of-inorganic-anions-to-multi-walled-carbon-nanotubes-studied-by-column-chromatography
#6
Florian Metzelder, Torsten C Schmidt
Sorption to carbon-based nanomaterials is typically studied in batch experiments. An alternative method offering advantages to study sorption is column chromatography. Sorbent packed columns are used and sorption data are determined by relating sorbate retention to that of a non-retarded tracer. We have now for the first time applied this technique to study the influence of environmental conditions on sorption of inorganic anions (bromide, nitrite, nitrate and iodide) to multi-walled carbon nanotubes. Deuterium oxide was used as non-retarded tracer...
April 6, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28364104/-space-time-analysis-of-over-limit-of-sodium-nitrite-in-cooked-meat-products-from-hunan-province-in-2010-2014
#7
Huiying Liao, Hengwen Zhao, Bo Yu
To determine over-limit status of sodium nitrite in cooked meat products in Hunan Province, and to provide scientific evidence for making health supervision.
 Methods: In accordance with the national standards for sampling and testing, data were analyzed by classical and spatial statistic methods.
 Results: The total over-limit rate of sodium nitrite was 5.5% in 731 samples. The relative higher sodium nitrite over-limit rates were Xiangxi Tujia and Miao autonomous prefecture and Zhangjiajie. October and February were the main months in nitrite over-limit...
March 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28352942/long-term-dietary-nitrite-and-nitrate-deficiency-causes-the-metabolic-syndrome-endothelial-dysfunction-and-cardiovascular-death-in-mice
#8
Mika Kina-Tanada, Mayuko Sakanashi, Akihide Tanimoto, Tadashi Kaname, Toshihiro Matsuzaki, Katsuhiko Noguchi, Taro Uchida, Junko Nakasone, Chisayo Kozuka, Masayoshi Ishida, Haruaki Kubota, Yuji Taira, Yuichi Totsuka, Shin-Ichiro Kina, Hajime Sunakawa, Junichi Omura, Kimio Satoh, Hiroaki Shimokawa, Nobuyuki Yanagihara, Shiro Maeda, Yusuke Ohya, Masayuki Matsushita, Hiroaki Masuzaki, Akira Arasaki, Masato Tsutsui
AIMS/HYPOTHESIS: Nitric oxide (NO) is synthesised not only from L-arginine by NO synthases (NOSs), but also from its inert metabolites, nitrite and nitrate. Green leafy vegetables are abundant in nitrate, but whether or not a deficiency in dietary nitrite/nitrate spontaneously causes disease remains to be clarified. In this study, we tested our hypothesis that long-term dietary nitrite/nitrate deficiency would induce the metabolic syndrome in mice. METHODS: To this end, we prepared a low-nitrite/nitrate diet (LND) consisting of an amino acid-based low-nitrite/nitrate chow, in which the contents of L-arginine, fat, carbohydrates, protein and energy were identical with a regular chow, and potable ultrapure water...
March 28, 2017: Diabetologia
https://www.readbyqxmd.com/read/28351967/concerted-regulation-of-renal-plasma-flow-and-glomerular-filtration-rate-by-renal-dopamine-and-nos-i-in-rats-on-high-salt-intake
#9
Mariano E Ibarra, Maria F Albertoni Borghese, Mónica P Majowicz, María C Ortiz, Fabián Loidl, Manuel Rey-Funes, Luis A Di Ciano, Fernando R Ibarra
Under high sodium intake renal dopamine (DA) increases while NOS I expression in macula densa cells (MD) decreases. To explore whether renal DA and NOS I, linked to natriuresis and to the stability of the tubuloglomerular feedback, respectively, act in concert to regulate renal plasma flow (RPF) and glomerular filtration rate (GFR). Male Wistar rats were studied under a normal sodium intake (NS, NaCl 0.24%) or a high sodium intake (HS, NaCl 1% in drinking water) during the 5 days of the study. For the last two days, the specific D1-like receptor antagonist SCH 23390 (1 mg kg bwt(-1) day(-1), sc) or a vehicle was administered...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28349706/unintentional-mass-sodium-nitrite-poisoning-with-a-fatality
#10
Changhwan Lee, Eun Jung Jang, Hyesun Yum, Young Shik Choi, Jeongik Hong
No abstract text is available yet for this article.
March 28, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28328022/modifications-to-the-azide-method-for-nitrate-isotope-analysis
#11
Ying Tu, Yunting Fang, Dongwei Liu, Yuepeng Pan
RATIONALE: The azide method for measuring the stable isotope ratios of nitrate (NO3(-) ) is easy to set up. However, the method requires spongy cadmium (Cd) or activated Cd powder which are not easy to prepare, and a toxic azide buffer is used. We aimed to use Cd powder directly to simplify preparation and to substantially reduce the azide dose. METHODS: The reaction conditions were optimized in order to maximize the NO3(-) reduction yield. The original azide buffer was diluted by 10- to 10000-fold with or without addition of sodium acetate to reduce O-exchange between nitrite (NO2(-) ) and H2 O...
May 30, 2016: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28322085/examination-of-the-effect-of-sodium-nitrite-on-gap-junction-function-during-ischaemia-and-reperfusion-in-anaesthetized-dogs
#12
Gottfried Miskolczi, Márton Gönczi, Mária Kovács, Ágnes Végh
It has previously been proved that sodium nitrite, infused prior to coronary artery occlusion or before reperfusion, results in marked antiarrhythmic effect in anaesthetized dogs. We have now examined whether this protection involves the modulation of gap junction (GJ) function by nitric oxide (NO), derived from nitrite administration under ischaemic conditions. Two groups of chloralose and urethane anaesthetized dogs, each containing 13 animals, were subjected to a 25 min period occlusion of the left anterior descending (LAD) coronary artery, followed by reperfusion...
March 2017: Acta Biologica Hungarica
https://www.readbyqxmd.com/read/28316466/effects-of-additions-of-monascus-and-laccaic-acid-on-the-color-and-quality-properties-of-nitrite-free-emulsion-sausage-during-refrigerated-storage
#13
Pil-Nam Seong, Hoa Van Ba, Yoon-Seok Kim, Sun-Moon Kang, Soo-Hyun Cho, Jin-Hyoung Kim, Beom-Young Park, Geun-Ho Kang, Sung-Sil Moon, Hyun-Woo Seo
This effect of Monascus and Laccaic acid on the chemical composition, physical, texture and sensory properties of sausage were investigated during storage. Eight treatments (T) of sausage such as T1 (12 ppm sodium nitrite), while T2, T3, T4, T5, T6 and T7 were formulated with different ratios of Monascus/Laccaic acid: 63/7.0, 108/12, 135/15, 59.5/10.5, 102/18 and 127.5/22.5 ppm, respectively. The batch formulated without nitrite or Monascus and laccaic acid was served as control (C). The control sausages had higher pH values compared to the treated ones at 3, 10 and 28 d storage (p<0...
2017: Korean Journal for Food Science of Animal Resources
https://www.readbyqxmd.com/read/28285190/nitrate-decreases-xanthine-oxidoreductase-mediated-nitrite-reductase-activity-and-attenuates-vascular-and-blood-pressure-responses-to-nitrite
#14
Célio Damacena-Angelis, Gustavo H Oliveira-Paula, Lucas C Pinheiro, Eduardo J Crevelin, Rafael L Portella, Luiz Alberto B Moraes, Jose E Tanus-Santos
Nitrite and nitrate restore deficient endogenous nitric oxide (NO) production as they are converted back to NO, and therefore complement the classic enzymatic NO synthesis. Circulating nitrate and nitrite must cross membrane barriers to produce their effects and increased nitrate concentrations may attenuate the nitrite influx into cells, decreasing NO generation from nitrite. Moreover, xanthine oxidoreductase (XOR) mediates NO formation from nitrite and nitrate. However, no study has examined whether nitrate attenuates XOR-mediated NO generation from nitrite...
March 6, 2017: Redox Biology
https://www.readbyqxmd.com/read/28284123/the-impact-of-high-hydrostatic-pressure-on-the-functionality-and-consumer-acceptability-of-reduced-sodium-naturally-cured-wieners
#15
Z Pietrasik, N J Gaudette, S P Johnston
The effects of high pressure processing (HPP; 600MPa for 3min at 8°C) on the quality and shelf life of reduced sodium naturally-cured wieners was studied. HPP did not negatively impact processing characteristics and assisted in extending shelf life of all wiener treatments up to a 12week storage period. At week 8, HPP wieners received higher acceptability scores, indicating HPP can effectively extend the sensory quality of products, including sodium reduced formulations containing natural forms of nitrite...
February 24, 2017: Meat Science
https://www.readbyqxmd.com/read/28280793/human-second-window-pre-conditioning-and-post-conditioning-by-nitrite-is-influenced-by-a-common-polymorphism-in-mitochondrial-aldehyde-dehydrogenase
#16
Julian O M Ormerod, Jonathan D W Evans, Hussain Contractor, Matteo Beretta, Sayqa Arif, Bernadette O Fernandez, Martin Feelisch, Bernd Mayer, Rajesh K Kharbanda, Michael P Frenneaux, Houman Ashrafian
Pre-conditioning is an exciting physiological phenomenon that, despite great efforts, has so far resisted translation to mainstream clinical medicine. Many potential triggers (e.g., ischemia of the organ in question or a remote organ, many different drugs) have been investigated, but recent work has implicated activation of mitochondrial aldehyde dehydrogenase (ALDH2) as central to the process. A genetic polymorphism, known as ALDH2*2, is common worldwide (present in up to 40% of Han Chinese people) and produces a functionally different enzyme...
February 2017: JACC. Basic to Translational Science
https://www.readbyqxmd.com/read/28272030/biomass-aggregation-influences-nan3-short-term-effects-on-anammox-bacteria-activity
#17
A Pedrouso, A Val Del Río, J L Campos, R Méndez, A Mosquera-Corral
The main bottleneck to maintain the long-term stability of the partial nitritation-anammox processes, especially those operated at low temperatures and nitrogen concentrations, is the undesirable development of nitrite oxidizing bacteria (NOB). When this occurs, the punctual addition of compounds with the capacity to specifically inhibit NOB without affecting the process efficiency might be of interest. Sodium azide (NaN3) is an already known NOB inhibitor which at low concentrations does not significantly affect the ammonia oxidizing bacteria (AOB) activity...
March 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28266762/downregulation-of-hif1-%C3%AE-smad-2-akt-and-bax-gene-expression-in-sodium-nitrite-induced-lung-injury-via-some-antioxidants
#18
Mai O Kadry, Hanaa Mahmoud Ali
The aim of the current study is to evaluate the efficacy of pretreatment with either l-arginine (L-arg) or Carnosine (Car) and their combination in ameliorating some of the biochemical indices induced in the lung of sodium nitrite (NaNO2 )-intoxicated rats. The results revealed that NaNO2 significantly increased serum tumor necrosis factor-α, C-reactive protein, heat shock proteins-70, vascular endothelial growth factor, and Interleukin 6. Moreover, transforming growth factor-β, hypoxia-inducible factor, Smad-2, Protein Kinase B (AKT), and Bax were overexpressed, whereas Bcl2 protein was downregulated compared with the normoxic group...
March 7, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28261254/interaction-of-polyamines-abscisic-acid-nitric-oxide-and-hydrogen-peroxide-under-chilling-stress-in-tomato-lycopersicon-esculentum-mill-seedlings
#19
Qiannan Diao, Yongjun Song, Dongmei Shi, Hongyan Qi
Polyamines (PAs) play a vital role in the responses of higher plants to abiotic stresses. However, only a limited number of studies have examined the interplay between PAs and signal molecules. The aim of this study was to elucidate the cross-talk among PAs, abscisic acid (ABA), nitric oxide (NO), and hydrogen peroxide (H2O2) under chilling stress conditions using tomato seedlings [(Lycopersicon esculentum Mill.) cv. Moneymaker]. The study showed that during chilling stress (4°C; 0, 12, and 24 h), the application of spermidine (Spd) and spermine (Spm) elevated NO and H2O2 levels, enhanced nitrite reductase (NR), nitric oxide synthase (NOS)-like, and polyamine oxidase activities, and upregulated LeNR relative expression, but did not influence LeNOS1 expression...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28244005/sodium-selenite-prevents-paraquat-induced-neurotoxicity-in-zebrafish
#20
Talise E Müller, Mauro E Nunes, Charlene C Menezes, Aline T Marins, Jossiele Leitemperger, Ana Carolina Lopes Gressler, Fabiano B Carvalho, Catiuscia Molz de Freitas, Vanessa A Quadros, Roselei Fachinetto, Denis B Rosemberg, Vania L Loro
Considering the antioxidant properties of sodium selenite (Na2SeO3) and the involvement of oxidative stress events in paraquat-induced neurotoxicity, this study investigated the protective effect of dietary Na2SeO3 on biochemical and behavioral parameters of zebrafish exposed to paraquat (PQ). Fish were pretreated with a Na2SeO3 diet for 21 days and then PQ (20 mg/kg) was administered intraperitoneally with six injections for 16 days. In the novel tank test, the Na2SeO3 diet prevented the locomotor impairments, as well as the increase in the time spent in the top area of the tank, and the exacerbation of freezing episodes...
February 27, 2017: Molecular Neurobiology
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