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https://www.readbyqxmd.com/read/29550133/short-communication-model-for-metritis-severity-predicts-that-disease-misclassification-underestimates-projected-milk-production-losses
#1
M M McCarthy, M W Overton
The objective of this research was to determine the effect of disease misclassification on the estimated effect of metritis on milk production. Misclassification introduces bias that usually results in an underestimation of the association between exposure (disease) and the outcome of interest (milk production). This distorted measure of association results from the comparison of an affected population (some of which may not truly be affected) to a nonaffected population (which often includes affected subjects that are unidentified)...
March 14, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29477523/predicting-blood-%C3%AE-hydroxybutyrate-using-milk-fourier-transform-infrared-spectrum-milk-composition-and-producer-reported-variables-with-multiple-linear-regression-partial-least-squares-regression-and-artificial-neural-network
#2
R S Pralle, K W Weigel, H M White
Prediction of postpartum hyperketonemia (HYK) using Fourier transform infrared (FTIR) spectrometry analysis could be a practical diagnostic option for farms because these data are now available from routine milk analysis during Dairy Herd Improvement testing. The objectives of this study were to (1) develop and evaluate blood β-hydroxybutyrate (BHB) prediction models using multivariate linear regression (MLR), partial least squares regression (PLS), and artificial neural network (ANN) methods and (2) evaluate whether milk FTIR spectrum (mFTIR)-based models are improved with the inclusion of test-day variables (mTest; milk composition and producer-reported data)...
February 21, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29429598/does-the-site-of-the-orthotopic-neobladder-outlet-matter-a-prospective-randomized-comparative-study
#3
Ahmed M Moeen, Ahmed S Safwat, Mohamed M Gadelmoula, Seham M Moeen, Hosny M Behnsawy, Ahmed A Shahat, Rabea A Gadelkareem, Diaa A Hameed, Hisham M Hammouda
BACKGROUND: To compare the results of urethral anastomosis to a button hole and to the lowest part of the anterior suture line during orthotopic neobladder substitution. METHODS: From January 2012 to December 2015, 87 consecutive male patients with invasive bladder cancer underwent radical cystectomy and Hautmann ileal neobladder. Patients were randomly divided into two groups; group I (44 patients), the outlet was created as a button-hole at the most dependent part of the pouch, group II (43 patients), the lowest 1 cm of the anterior suture line of the pouch was left open as an outlet...
January 31, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29340299/prospective-study-of-the-feasibility-of-point-of-care-testing-strategy-for-carbapenem-resistant-organism-detection
#4
Rahul Pannala, Bruce Baldwin, Vijay Aluru, Thomas E Grys, Jordan Holmes, Laurence J Miller, M Edwyn Harrison, Cuong C Nguyen, Fred C Tenover, David Persing, Douglas O Faigel
Background/aims:  In an investigator-initiated, prospective study, we evaluated the feasibility of a five-gene sequence point-of-care (POC) testing strategy (Xpert CARBA-R Assay, Cepheid Inc., Sunnyvale, CA, USA), compared to reference laboratory PCR (48 - 72 hours turnaround time, two gene sequences), in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and in a hospital outbreak investigation. Methods:  After informed consent, patients undergoing ERCP (September 2015 - April 2016, n = 191) at Mayo Clinic and potential hospital contacts (n = 9) of an index carbapenem-resistant organism (CRO)-positive inpatient were included...
January 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29238570/impact-of-asa-score-misclassification-on-nsqip-predicted-mortality-a-retrospective-analysis
#5
Alex Helkin, Sumeet V Jain, Angelika Gruessner, Maureen Fleming, Leslie Kohman, Michael Costanza, Robert N Cooney
Background: The ASA physical classification score has a major impact on the observed/expected (O/E) mortality ratio in the NSQIP General Vascular Mortality Model. The difference in predicted mortality is greatest between ASAs 3 and 4. We hypothesized under-classified ASA scores significantly affect the O/E mortality. Methods: We conducted a retrospective review of NSQIP essential surgery cases from January 2014 to December 2014 ( n  = 1264) with mortality sub-analysis ( n  = 33) at our institution...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/28992032/effects-of-a-multi-strain-bacillus-spp-direct-fed-microbial-and-a-protease-enzyme-on-growth-performance-nutrient-digestibility-blood-characteristics-fecal-microbiota-and-noxious-gas-emissions-of-grower-pigs-fed-corn-soybean-meal-based-diets-a-meta-analysis
#6
L Payling, I H Kim, M C Walsh, E Kiarie
Three studies involving 352 grower pigs were conducted to determine the effects of dietary supplementation with multistrain spp. direct-fed microbial (DFM) and protease, alone or in combination, on growth performance, nutrient digestibility, blood characteristics, fecal microbiota, and noxious gas emissions, and to use a meta-analysis to increase the reliability of the findings. Treatments ( = 4) were set up as a 2 × 2 factorial design with 2 levels of protease (0 and 5.000/6.000 units/kilogram of feed [U/KG]) and 2 levels of DFM (0 and 1...
September 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28653369/recognition-of-chronic-migraine-by-medicine-trainees-a-cross-sectional-survey
#7
Priyanka Yadav, Alec L Bradley, Jonathan H Smith
OBJECTIVE: Chronic migraine is a diagnosis that can be abstracted through the clinical history, although some providers may struggle in properly applying diagnostic criteria. We aimed to learn how well medicine trainees would be able to recognize the diagnostic criteria for chronic migraine and apply that medical knowledge to case vignettes illustrating different symptom interpretation strategies of the identical information. METHODS: An electronic, anonymous and multiple-choice response questionairre assessing selected trainee characteristics, headache case vignettes, and chronic migraine diagnostic criteria was distributed to all regional medicine program directors and coordinators in Kentucky and surrounding states...
September 2017: Headache
https://www.readbyqxmd.com/read/28588661/quantification-of-the-articular-view-of-the-elbow-afforded-by-standard-portals-using-30%C3%A2-arthroscopy
#8
Robert Moverley, Henry B Colaco, Bran Rudran, Matthew Szarko, Magnus Arnander, Duncan Tennent
BACKGROUND: The present study quantifies the field of view (FOV) from standard arthroscopy portals and aims to identify anatomical regions where the FOV is limited. METHODS: Eleven cadaveric elbows were examined through standard anteromedial, anterolateral and posterior portals. The FOV was marked with dye using a spinal needle. The articular surfaces were then exposed and the percentage FOV seen was calculated. FOV percentage areas were compared using a Student's t-test (JMP, version 10, SAS Institute Inc...
July 2017: Shoulder & Elbow
https://www.readbyqxmd.com/read/28391558/a-survey-of-the-knowledge-of-african-american-women-about-prostate-cancer-screening
#9
Taryn Y Eastland
Prostate cancer is the second most common cancer diagnosed in men. Its incident and mortality rates are generally higher in populations of African descent. The scientific community recommends that men should be informed of the benefits, risks, and limitations of screening in order to make an informed decision regarding participation in prostate cancer screening. Women are known to act as the healthcare gatekeeper for the family. As such, African-American (AA) women could facilitate the informed decision-making process by providing prostate cancer and screening information to AA men...
April 8, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28291785/transcriptome-difference-and-potential-crosstalk-between-liver-and-mammary-tissue-in-mid-lactation-primiparous-dairy-cows
#10
Dengpan Bu, Massimo Bionaz, Mengzhi Wang, Xuemei Nan, Lu Ma, Jiaqi Wang
Liver and mammary gland are among the most important organs during lactation in dairy cows. With the purpose of understanding both the different and the complementary roles and the crosstalk of those two organs during lactation, a transcriptome analysis was performed on liver and mammary tissues of 10 primiparous dairy cows in mid-lactation. The analysis was performed using a 4×44K Bovine Agilent microarray chip. The transcriptome difference between the two tissues was analyzed using SAS JMP Genomics using ANOVA with a false discovery rate correction (FDR)...
2017: PloS One
https://www.readbyqxmd.com/read/28284691/relationships-between-early-life-growth-intake-and-birth-season-with-first-lactation-performance-of-holstein-dairy-cows
#11
H Chester-Jones, B J Heins, D Ziegler, D Schimek, S Schuling, B Ziegler, M B de Ondarza, C J Sniffen, N Broadwater
The objective was to determine the relationships between early-life parameters [including average daily gain (ADG), body weight (BW), milk replacer intake, starter intake, and birth season] and the first-lactation performance of Holstein cows. We collected data from birth years 2004 to 2012 for 2,880 Holstein animals. Calves were received from 3 commercial dairy farms and enrolled in 37 different calf research trials at the University of Minnesota Southern Research and Outreach Center from 3 to 195 d. Upon trial completion, calves were returned to their respective farms...
May 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/27920475/impact-of-frailty-on-approach-to-colonic-resection-laparoscopy-vs-open-surgery
#12
COMPARATIVE STUDY
Catalina Mosquera, Konstantinos Spaniolas, Timothy L Fitzgerald
AIM: To understand the influence of frailty on postoperative outcomes for laparoscopic and open colectomy. METHODS: Data were obtained from the National Surgical Quality Improvement Program (2005-2012) for patients undergoing colon resection [open colectomy (OC) and laparoscopic colectomy (LC)]. Patients were classified as non-frail (0 points), low frailty (1 point), moderate frailty (2 points), and severe frailty (≥ 3) using the Modified Frailty Index. 30-d mortality and complications were used as the primary end point and analyzed for the overall population...
November 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27881143/weekly-versus-every-three-weeks-platinum-based-chemoradiation-regimens-for-head-and-neck-cancer
#13
James M Melotek, Benjamin T Cooper, Matthew Koshy, Joshua S Silverman, Michael T Spiotto
BACKGROUND: The majority of chemoradiation (CRT) trials for locally advanced head and neck squamous cell carcinoma (HNSCC) have relied on platinum-based chemotherapy regimens administered every-3-weeks. However, given the increased utilization of weekly platinum regimens, it remains unclear how different chemotherapy schedules compare regarding efficacy and toxicity. METHODS: We retrospectively identified 212 patients with HNSCC who were treated at a single academic medical center with concurrent platinum-based CRT given weekly (N = 68) or every-three-weeks (N = 144)...
November 24, 2016: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27636213/female-urethral-diverticulum-presentation-diagnosis-and-predictors-of-outcomes-after-surgery
#14
Sherif A El-Nashar, Ruchira Singh, Melissa M Bacon, Shunaha Kim-Fine, John A Occhino, John B Gebhart, Christopher J Klingele
INTRODUCTION AND HYPOTHESIS: To report on clinical presentation, diagnosis, and outcomes after treatment of female urethral diverticulum (UD). METHODS: Using a record linkage system, women with a new diagnosis of UD at Mayo Clinic from January 1, 1980, through December 31, 2011, were identified. The presenting symptoms, clinical characteristics, diagnosis, and management of women presenting with UD were recorded. Outcomes after surgery were assessed using survival analysis...
November 2016: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/27514658/esr1-erbb2-and-ki67-mrna-expression-predicts-stage-and-grade-of-non-muscle-invasive-bladder-carcinoma-nmibc
#15
Johannes Breyer, Ralph M Wirtz, Mark Laible, Kornelia Schlombs, Philipp Erben, Maximilian Christian Kriegmair, Robert Stoehr, Sebastian Eidt, Stefan Denzinger, Maximilian Burger, Arndt Hartmann, Wolfgang Otto
Pathological staging and grading are crucial for risk assessment in non-muscle-invasive bladder cancer (NMIBC). Molecular grading might support pathological evaluation and minimize interobserver variability. In this study, the well-established breast cancer markers ESR1, PGR, ERBB2, and MKI67 were evaluated as potential molecular markers to support grading and staging in NMIBC. We retrospectively analyzed clinical data and formalin-fixed paraffin-embedded tissues (FFPE) of patients with NMIBC. Messenger RNA (mRNA) expression of the aforementioned markers was measured by single-step reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) using RNA-specific TaqMan assays...
November 2016: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/27459973/in-vitro-evaluation-of-osteoblast-responses-to-carbon-nanotube-coated-titanium-surfaces
#16
K Subramani, S N Pandruvada, D A Puleo, J K Hartsfield, S S Huja
BACKGROUND: The effects of surface roughness and carboxyl functionalization of multi-walled carbon nanotubes (MWCNTs) mixed with collagen coated onto titanium (Ti) substrates on MC3T3-E1 osteoblasts were evaluated. METHODS: The proliferation, differentiation, and matrix mineralization were investigated using (1) smooth-surfaced Ti discs, (2) Ti discs coated with collagen and MWCNT (Ti-MWCNT), and (3) Ti discs coated with collagen and MWCNT-COOH (Ti-MWCNT-COOH) for applications in orthodontic mini screw implants (MSIs)...
December 2016: Progress in Orthodontics
https://www.readbyqxmd.com/read/27294398/excellent-intra-and-inter-observer-reproducibility-of-wrist-circumference-measurements-in-obese-children-and-adolescents
#17
Giuseppe Campagna, Simona Zampetti, Alessia Gallozzi, Sara Giansanti, Claudio Chiesa, Lucia Pacifico, Raffaella Buzzetti
In a previous study, we found that wrist circumference, in particular its bone component, was associated with insulin resistance in a population of overweight/obese children. The aim of the present study was to evaluate the intra- and inter-operator variability in wrist circumference measurement in a population of obese children and adolescents. One hundred and two (54 male and 48 female) obese children and adolescents were consecutively enrolled. In all subjects wrist circumferences were measured by two different operators two times to assess intra- and inter-operator variability...
2016: PloS One
https://www.readbyqxmd.com/read/27179246/varicose-veins-new-trends-in-treatment-in-a-vascular-surgery-unit
#18
Daniela P Mazzaccaro, Silvia Stegher, Maria Teresa Occhiuto, Lorenzo Muzzarelli, Giovanni Malacrida, Giovanni Nano
AIM: Less invasive techniques such as foam sclerotherapy, endovenous laser or radiofrequency ablation have recently been introduced as a valid alternative to surgery for the treatment of varicose veins (VVs). We retrospectively reviewed our experience in the treatment of VVs with particular attention to how our therapeutic approach has changed over the last years. MATERIAL OF STUDY: Data of all patients consecutively treated from September 1st 2013 to July 31st 2015 for both primitive and recurrent VVs were retrospectively collected and analyzed...
2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27137907/growth-patterns-of-the-neurocentral-synchondrosis-ncs-in-immature-cadaveric-vertebra
#19
Laurel Blakemore, Richard Schwend, Behrooz A Akbarnia, Megan Dumas, John Schmidt
STUDY DESIGN: Gross anatomic study of osteological specimens. OBJECTIVES: To evaluate the age of closure for the neurocentral synchondrosis (NCS) in all 3 regions of the spine in children aged 1 to 18 years old. SUMMARY OF BACKGROUND DATA: The ossification of the human vertebra begins from a vertebral body ossification center and a pair of neural ossification centers located within the centrum called the NCS. These bipolar cartilaginous centers of growth contribute to the growth of the vertebral body, spinal canal, and posterior elements of the spine...
April 30, 2016: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/27017524/ophthalmic-surgical-simulation-in-training-dexterity-in-dominant-and-nondominant-hands-results-from-a-pilot-study
#20
Luis A Gonzalez-Gonzalez, Abhishek R Payal, Jose E Gonzalez-Monroy, Mary K Daly
PURPOSE: To determine whether a structured training program using the validated EYESI surgical simulator improves dexterity in nondominant (ND) hands. SETTING: Academic tertiary referral center. DESIGN: Nonrandomized, prospective study. METHODS: Subjects who chose to participate and provided informed consent completed a structured simulation training program, which included a baseline test, 3 sessions of repeated tasks, and a final test on capsulorhexis in dominant (D) and ND hands...
July 2016: Journal of Surgical Education
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