Lorena Carmona-Rodríguez, Aaron S Gajadhar, Irene Blázquez-García, Laura Guerrero, Manuel A Fernández-Rojo, Iker Uriarte, Maricruz Mamani-Huanca, Ángeles López-Gonzálvez, Sergio Ciordia, Antonio Ramos, José Ignacio Herrero, Maite G Fernández-Barrena, María Arechederra, Carmen Berasain, Jorge Quiroga, Bruno Sangro, Josepmaría Argemi, Fernando Pardo, Fernando Rotellar, Daniel López, Coral Barbas, Matías A Ávila, Fernando J Corrales
The liver is the only solid organ capable of regenerating itself to regain 100% of its mass and function after liver injury and/or partial hepatectomy (PH). This exceptional property represents a therapeutic opportunity for severe liver disease patients. However, liver regeneration (LR) might fail due to poorly understood causes. Here, we have investigated the regulation of liver proteome and phosphoproteome at a short time after PH (9 h), to depict a detailed mechanistic background of the early LR phase...
May 12, 2023: BioFactors