Kate T Simms, Adam Keane, Diep Thi Ngoc Nguyen, Michael Caruana, Michaela T Hall, Gigi Lui, Cindy Gauvreau, Owen Demke, Marc Arbyn, Partha Basu, Nicolas Wentzensen, Beatrice Lauby-Secretan, Andre Ilbawi, Raymond Hutubessy, Maribel Almonte, Silvia De Sanjosé, Helen Kelly, Shona Dalal, Linda O Eckert, Nancy Santesso, Nathalie Broutet, Karen Canfell
In 2020, the World Health Organization (WHO) launched a strategy to eliminate cervical cancer as a public health problem. To support the strategy, the WHO published updated cervical screening guidelines in 2021. To inform this update, we used an established modeling platform, Policy1-Cervix, to evaluate the impact of seven primary screening scenarios across 78 low- and lower-middle-income countries (LMICs) for the general population of women. Assuming 70% coverage, we found that primary human papillomavirus (HPV) screening approaches were the most effective and cost-effective, reducing cervical cancer age-standardized mortality rates by 63-67% when offered every 5 years...
December 2023: Nature Medicine