keyword
MENU ▼
Read by QxMD icon Read
search

single particle analysis

keyword
https://www.readbyqxmd.com/read/28525615/embolic-foreign-material-in-the-central-nervous-system-of-pediatric-autopsy-patients-with-instrumented-heart-disease
#1
Matthew Torre, Mirna Lechpammer, Vera Paulson, Sanjay Prabhu, Audrey C Marshall, Amy L Juraszek, Robert F Padera, Elizabeth A Bundock, Sara O Vargas, Rebecca D Folkerth
Upon detection of foreign-body embolization to the central nervous system (CNS) following a specific invasive cardiovascular procedure in 1 autopsied child, we undertook a quality assurance analysis to determine whether other patients had had similar events. Autopsies of all infants and children with history of cardiac catheterization, heart surgery on cardiopulmonary bypass, and/or extracorporeal membrane oxygenation over a 5-year period at a single tertiary care institution were reviewed for light-microscopic evidence of foreign material...
May 19, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28525257/self-etch-adhesive-as-a-carrier-for-acp-nanoprecursors-to-deliver-biomimetic-remineralization
#2
Zhifang Wu, Xiaokan Wang, Zhe Wang, Changyu Shao, Xiaoting Jin, Leiqing Zhang, Haihua Pan, Ruikang Tang, Baiping Fu
Lab biomineralization should be carried out in an actual clinical practice. This study evaluated self-etch adhesive as a carrier for amorphous calcium phosphate (ACP) nanoprecursors to continuously deliver biomimetic remineralization of self-assembly type I collagen and demineralized dentin. Si-containing ACP particles (Si-ACP) stabilized with polyaspartic acid (PAsp) were synthesized and characterized by transmission electron microscopy (TEM), scanning electron microscopy-energy-dispersive X-ray spectroscopy, Fourier transform infrared analysis, X-ray powder diffractometry, and X-ray phototelectron spectroscopy...
May 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28516056/simultaneous-micronization-and-purification-of-bioactive-fraction-by-supercritical-antisolvent-technology
#3
Stevanus Hiendrawan, Bambang Veriansyah, Edward Widjojokusumo, Raymond R Tjandrawinata
Simultaneous micronization and purification of DLBS3233 bioactive fraction, a combination of two Indonesian herbals Lagerstroemia speciosa and Cinnamomum burmannii has been successfully performed via supercritical anti-solvent (SAS) technology. The objective of the present study was to investigate the effectiveness of SAS technology to micronize and reduce coumarin content of DLBS3233. The effects of four SAS process parameters, i.e. pressure, temperature, concentration and solution flow rate on particle formation were investigated...
April 2017: Journal of Advanced Pharmaceutical Technology & Research
https://www.readbyqxmd.com/read/28514062/locoregional-therapy-with-%C3%AE-emitting-trastuzumab-against-peritoneal-metastasis-of-her2-positive-gastric-cancer-in-mice
#4
Huizi Keiko Li, Yukie Morokoshi, Kotaro Nagatsu, Tadashi Kamada, Sumitaka Hasegawa
Peritoneal metastasis of gastric cancer (PMGC) is incurable and thus has an extremely poor prognosis. We have found however that locoregionally administered trastuzumab armed with a radionuclide astatine-211 ((211) At)-emitting α-particle ((211) At-trastuzumab) is effective against HER2-positive PMGC in a xenograft mouse model. We first observed that (211) At-trastuzumab can specifically bind and effectively kill NCI-N87 (N87) cells, which are HER2-positive human metastatic GC cells, both in vitro and in subcutaneous tumors...
May 17, 2017: Cancer Science
https://www.readbyqxmd.com/read/28513474/dielectric-analysis-based-on-spherical-shell-model-for-cationic-and-anionic-spherical-polyelectrolyte-brushes
#5
Xiaoxia Guo, Kongshuang Zhao
We report here a dielectric study on cationic and anionic spherical polyelectrolyte brushes (SPBs) (consisting of a polystyrene (PS) core and poly (2-aminoethylmethacrylate hydrochloride (PAEMH) chains or poly (acrylic acid) (PAA) chains grafted onto the core) suspensions over a frequency range of 40 Hz to 110 MHz. The relaxation behavior of the suspensions shows significant changes in the brush layer properties when changing particles mass fraction or pH of system. After eliminating electrode polarization effect at low frequency, two definite relaxations related to the interfacial polarization, around 100 kHz and 10 MHz respectively, are observed...
May 17, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28512091/conformational-flexibility-in-the-immunoglobulin-like-domain-of-the-hepatitis-c-virus-glycoprotein-e2
#6
Ieva Vasiliauskaite, Ania Owsianka, Patrick England, Abdul Ghafoor Khan, Sarah Cole, Dorothea Bankwitz, Steven K H Foung, Thomas Pietschmann, Joseph Marcotrigiano, Felix A Rey, Arvind H Patel, Thomas Krey
The hepatitis C virus (HCV) glycoprotein E2 is the major target of neutralizing antibodies and is therefore highly relevant for vaccine design. Its structure features a central immunoglobulin (Ig)-like β-sandwich that contributes to the binding site for the cellular receptor CD81. We show that a synthetic peptide corresponding to a β-strand of this Ig-like domain forms an α-helix in complex with the anti-E2 antibody DAO5, demonstrating an inside-out flip of hydrophobic residues and a secondary structure change in the composite CD81 binding site...
May 16, 2017: MBio
https://www.readbyqxmd.com/read/28511427/role-of-omega-3-fatty-acids-on-lipid-profile-in-diabetic-dyslipidaemia-single-blind-randomised-clinical-trial
#7
Shaylika Chauhan, Hanish Kodali, Jawad Noor, Karuna Ramteke, Vidisha Gawai
INTRODUCTION: Diabetic dyslipidaemia is characterised by hypertriglyceridaemia, low High Density Lipoprotein (HDL), postprandial lipimea, small and dense LDL particles is considered to be a major predisposing factor for various macrovascular complications. Omega-3 fatty acids are fish oil derivative introduced in the market for dyslipidaemia associated with increased triglyceride level. AIM: To study the effect of omega-3 fatty acids on lipid profile in Type II diabetes patients...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28508254/comparison-of-pain-within-24%C3%A2-h-after-uterine-artery-embolization-with-tris-acryl-gelatin-microspheres-versus-gelatin-sponge-particles-for-leiomyoma
#8
Tetsuya Katsumori, Hisatomi Arima, Shunsuke Asai, Natsuko Hayashi, Hiroshi Miura
PURPOSE: To compare acute pain after uterine artery embolization (UAE) with tris-acryl gelatin microspheres (TAGM) versus gelatin sponge particles (GS) for leiomyoma. MATERIALS AND METHODS: This was a single-institution, retrospective study. Between July 2008 and November 2016, 101 consecutive patients with symptomatic uterine leiomyoma underwent UAE with the same protocol for post-procedural pain. GS was employed with near-stasis endpoint for the first 49 patients, whereas TAGM was used with limited endpoint for the next 52 patients...
May 15, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28507763/investigation-of-cloud-point-extraction-for-the-analysis-of-metallic-nanoparticles-in-a-soil-matrix
#9
Hind El Hadri, Vincent A Hackley
The characterization of manufactured nanoparticles (MNPs) in environmental samples is necessary to assess their behavior, fate and potential toxicity. Several techniques are available, but the limit of detection (LOD) is often too high for environmentally relevant concentrations. Therefore, pre-concentration of MNPs is an important component in the sample preparation step, in order to apply analytical tools with a LOD higher than the ng kg(-1) level. The objective of this study was to explore cloud point extraction (CPE) as a viable method to pre-concentrate gold nanoparticles (AuNPs), as a model MNP, spiked into a soil extract matrix...
2017: Environmental Science. Nano
https://www.readbyqxmd.com/read/28507703/advanced-electroanalytical-chemistry-at-nanoelectrodes
#10
Yi-Lun Ying, Zhifeng Ding, Dongping Zhan, Yi-Tao Long
Nanoelectrodes, with dimensions below 100 nm, have the advantages of high sensitivity and high spatial resolution. These electrodes have attracted increasing attention in various fields such as single cell analysis, single-molecule detection, single particle characterization and high-resolution imaging. The rapid growth of novel nanoelectrodes and nanoelectrochemical methods brings enormous new opportunities in the field. In this perspective, we discuss the challenges, advances, and opportunities for nanoelectrode fabrication, real-time characterizations and high-performance electrochemical instrumentation...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28505743/complementary-mode-analyses-between-sub-and-superdiffusion
#11
Takuya Saito, Takahiro Sakaue
Several subdiffusive stochastic processes in nature, e.g., the motion of a tagged monomer in polymers, the height fluctuation of interfaces, particle dynamics in single-file diffusion, etc., can be described rigorously or approximately by the superposition of various modes whose relaxation times are broadly distributed. In this paper, we propose a mode analysis generating superdiffusion, which is paired with or complementary to subdiffusion. The key point in our discussion lies in the identification of a pair of conjugated variables, which undergo sub- and superdiffusion, respectively...
April 2017: Physical Review. E
https://www.readbyqxmd.com/read/28501440/classification-of-microcrystalline-celluloses-via-structures-of-individual-particles-measured-by-synchrotron-radiation-x-ray-micro-computed-tomography
#12
Longwei Fang, Xianzhen Yin, Li Wu, Yaping He, Yuanzhi He, Wei Qin, Fanyue Meng, Peter York, Xu Xu, Jiwen Zhang
Microcrystalline cellulose (MCC) is one of the most important excipients due to its outstanding binding and tableting properties. Owing to the absence of high resolution characterization techniques at the single particle scale, 3D (three dimension) microstructure of MCC and its effects on formulation performance remain unexamined. The aim of this work was to establish a methodology for single particles of MCC type 102 based on synchrotron radiation X-ray micro computed tomography (SR-μCT), principal component analysis (PCA) and partial least square discriminant analysis (PLSDA)...
May 10, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28501339/x-ray-free-electron-laser-single-particle-analysis-for-biological-systems
#13
REVIEW
Osamu Miyashita, Yasumasa Joti
The X-ray free electron laser (XFEL) is a new light source that can produce coherent, ultra-brilliant, femtosecond X-ray pulses. This X-ray beam provides new possibilities for studies in structural biology. In this review, we survey the applications of XFEL to biological systems, with an emphasis on studies of noncrystalline samples. Although atomic-level modeling is not yet achievable, this method enables high-throughput, damage-free imaging of biological samples under near-physiological conditions and is being rapidly developed...
May 10, 2017: Current Opinion in Structural Biology
https://www.readbyqxmd.com/read/28499337/optically-encoded-semiconducting-polymer-dots-with-single-wavelength-excitation-for-barcoding-and-tracking-of-single-cells
#14
Chun-Ting Kuo, Hong-Shang Peng, Yu Rong, Jiangbo Yu, Wei Sun, Bryant S Fujimoto, Daniel T Chiu
Multiplexed optical encoding is emerging as a powerful technique for high-throughput cellular analysis and molecular assays. Most of the developed optical barcodes, however, either suffer from large particle size or are incompatible with most commercial optical instruments. Here, a new type of nanoscale fluorescent barcodes (Pdot barcodes) was prepared from semiconducting polymers. The Pdot barcodes possess the merits of small size (~20 nm in diameter), narrow emission bands (FWHM of 30-40 nm), three-color emissions (blue, green, and red) under single-wavelength excitation, a high brightness, good pH and thermal stability, and efficient cellular uptake...
May 12, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28498686/intense-laser-solid-state-physics-unraveling-the-difference-between-semiconductors-and-dielectrics
#15
C R McDonald, G Vampa, P B Corkum, T Brabec
Experiments on intense laser driven dielectrics have revealed population transfer to the conduction band to be oscillatory in time. This is in stark contrast to ionization in semiconductors and is currently unexplained. Current ionization theories neglect coupling between the valence and conduction band and therewith, the dynamic Stark shift. Our single-particle analysis identifies this as a potential reason for the different ionization behavior. The dynamic Stark shift increases the band gap with increasing laser intensities, thus suppressing ionization to an extent where virtual population oscillations become dominant...
April 28, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28498673/single-particle-dynamics-at-the-intrinsic-surface-of-various-apolar-aprotic-dipolar-and-hydrogen-bonding-liquids-as-seen-from-computer-simulations
#16
Balázs Fábián, Marcello Sega, George Horvai, Pal Jedlovszky
We investigate the single molecule dynamics at the intrinsic liquid/vapor interface of five different molecular liquids (carbon tetrachloride, acetone, acetonitrile, methanol and water). After assessing that the characteristic residence times in the surface layer are long enough for a meaningful definition of several transport properties within the layer itself, we characterize the dynamics of the individual molecules at the liquid surface by analyzing their normal and lateral mean square displacements and lateral velocity autocorrelation functions and, in the case of the hydrogen bonding liquids (i...
May 12, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28498657/surface-enhanced-raman-spectroscopy-a-facile-and-rapid-method-for-the-chemical-components-study-of-individual-atmospheric-aerosol
#17
Yu Fu, Christian Kuppe, Ventsislav Kolev Valev, Hongbo Fu, Liwu Zhang, Jianmin Chen
A simple and rapid method for detecting chemical components of individual aerosol particles on Klarite substrate with surface-enhanced Raman spectroscopy (SERS) is described. For both single simulated aerosol particles and ambient atmospheric particles, this new analytical method promotes the enhancement factor of the Raman signal. The spectra of ammonium sulfate and naphthalene particles at the microscopic level are enhanced by a factor of 6 and therefore greatly improve the detection of the chemical composition of an individual aerosol particle...
May 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28498373/genomic-exploration-of-individual-giant-ocean-viruses
#18
William H Wilson, Ilana C Gilg, Mohammad Moniruzzaman, Erin K Field, Sergey Koren, Gary R LeCleir, Joaquín Martínez Martínez, Nicole J Poulton, Brandon K Swan, Ramunas Stepanauskas, Steven W Wilhelm
Viruses are major pathogens in all biological systems. Virus propagation and downstream analysis remains a challenge, particularly in the ocean where the majority of their microbial hosts remain recalcitrant to current culturing techniques. We used a cultivation-independent approach to isolate and sequence individual viruses. The protocol uses high-speed fluorescence-activated virus sorting flow cytometry, multiple displacement amplification (MDA), and downstream genomic sequencing. We focused on 'giant viruses' that are readily distinguishable by flow cytometry...
May 12, 2017: ISME Journal
https://www.readbyqxmd.com/read/28490134/changes-in-the-structure-and-dissociation-of-soybean-protein-isolate-induced-by-ultrasound-assisted-acid-pretreatment
#19
Liurong Huang, Xiaona Ding, Chunhua Dai, Haile Ma
Structure and dissociation properties of soybean protein isolate (SPI) induced by ultrasound and acid were investigated. Results of solubility showed that ultrasound-assisted acid had no effect on the content of soluble aggregates in SPI. Increase of fluorescence intensity and red-shift of maximum emission wavelength indicated that acid induced molecular unfolding of SPI and exposure of hydrophobic groups. Circular dichroism spectra showed that ultrasound-assisted acid pretreatment resulted in increases in the α-helix content by 29...
October 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28484226/pattern-analysis-of-laser-tattoo-interactions-for-picosecond-and-nanosecond-domain-1-064-nm-neodymium-doped-yttrium-aluminum-garnet-lasers-in-tissue-mimicking-phantom
#20
Keun Jae Ahn, Zhenlong Zheng, Tae Rin Kwon, Beom Joon Kim, Hye Sun Lee, Sung Bin Cho
During laser treatment for tattoo removal, pigment chromophores absorb laser energy, resulting in fragmentation of the ink particles via selective photothermolysis. The present study aimed to outline macroscopic laser-tattoo interactions in tissue-mimicking (TM) phantoms treated with picosecond- and nanosecond-domain lasers. Additionally, high-speed cinematographs were captured to visualize time-dependent tattoo-tissue interactions, from laser irradiation to the formation of photothermal and photoacoustic injury zones (PIZs)...
May 8, 2017: Scientific Reports
keyword
keyword
111790
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"