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https://www.readbyqxmd.com/read/28110459/calcium-phosphate-ceramics-and-polysaccharide-based-hydrogel-scaffolds-combined-with-mesenchymal-stem-cell-differently-support-bone-repair-in-rats
#1
Sophie Frasca, Françoise Norol, Catherine Le Visage, Jean-Marc Collombet, Didier Letourneur, Xavier Holy, Elhadi Sari Ali
Research in bone tissue engineering is focused on the development of alternatives to autologous bone grafts for bone reconstruction. Although multiple stem cell-based products and biomaterials are currently being investigated, comparative studies are rarely achieved to evaluate the most appropriate approach in this context. Here, we aimed to compare different clinically relevant bone tissue engineering methods and evaluated the kinetic repair and the bone healing efficiency supported by mesenchymal stem cells and two different biomaterials, a new hydrogel scaffold and a commercial hydroxyapatite/tricalcium phosphate ceramic, alone or in combination...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28109812/chitosan-as-a-vehicle-for-growth-factor-delivery-various-preparations-and-their-applications-in-bone-tissue-regeneration
#2
REVIEW
Jayachandran Venkatesan, Sukumaran Anil, Se-Kwon Kim, Min Suk Shim
The replacement of conventional autografts and allografts by bone fragments constructed from alternate materials, cells, and molecules (growth factors, drugs, etc.) is an exciting prospect in the field of bone tissue engineering. Bone morphogenetic protein-2 (BMP-2) is a growth factor that has been extensively studied from this point of view. This review analyzes the relevance of chitosan and its derivatives and composites with various materials such as ceramics, heparin, silica, stem cells, titanium implants, etc...
January 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28108961/effects-of-negatively-and-positively-charged-ti-metal-surfaces-on-ceramic-coating-adhesion-and-cell-response
#3
Rodney Marcelo do Nascimento, Vanessa Rafaela de Carvalho, José Silvio Govone, Antônio Carlos Hernandes, Nilson Cristino da Cruz
This manuscript reports an evaluation of the effects of simple chemical-heat treatments on the deposition of different ceramic coatings, i.e., TiO2, CaTiO3 and CaP, on commercially pure titanium (cp-Ti) and Ti6Al4V and the influence of the coatings on cells interaction with the surfaces. The ceramic materials were prepared by the sol-gel method and the coating adhesion was analyzed by pull-off bending tests. The wettability of positively or negatively charged surfaces was characterized by contact angle measurements, which also enabled the calculation of the surface free energy through the polar-apolar liquids approach...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28108237/poly-trimethylene-carbonate-based-composite-materials-for-reconstruction-of-critical-sized-cranial-bone-defects-in-sheep
#4
Ni Zeng, Anne C van Leeuwen, Dirk W Grijpma, Ruud R M Bos, Roel Kuijer
PURPOSE: The use of ceramic materials in repair of bone defects is limited to non-load-bearing sites. We tested poly(trimethylene carbonate) (PTMC) combined with β-tricalcium phosphate or biphasic calcium phosphate particles for reconstruction of cranial defects. MATERIALS AND METHODS: PTMC-calcium phosphate composite matrices were implanted in cranial defects in sheep for 3 and 9 months. Micro-computed tomography quantification and histological observation were performed for analysis...
December 18, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28107811/biomimetic-versus-sintered-calcium-phosphates-the-in-vitro-behavior-of-osteoblasts-and-mesenchymal-stem-cells
#5
Joanna Maria Sadowska, Jordi Guillem-Marti, Edgar B Montufar, Montserrat Espanol, Maria-Pau Ginebra
The fabrication of calcium phosphates using biomimetic routes, namely, precipitation processes at body temperature, results in distinct features compared to conventional sintered calcium phosphate ceramics, such as a high specific surface area and micro or nanometric crystal size. The aim of this paper is to analyze the effects of these parameters on cell response, focusing on two bone cell types: rat mesenchymal stem cells (rMSCs) and human osteoblastic cells (SaOS-2). Biomimetic calcium deficient hydroxyapatite (CDHA) was obtained by a low temperature setting reaction, and α-tricalcium phosphate (α-TCP) and β- tricalcium phosphate (β-TCP) were subsequently obtained by sintering CDHA either at 1400 °C or 1100 °C...
January 20, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28107637/survival-predictions-of-ceramic-crowns-using-statistical-fracture-mechanics
#6
S Nasrin, N Katsube, R R Seghi, S I Rokhlin
This work establishes a survival probability methodology for interface-initiated fatigue failures of monolithic ceramic crowns under simulated masticatory loading. A complete 3-dimensional (3D) finite element analysis model of a minimally reduced molar crown was developed using commercially available hardware and software. Estimates of material surface flaw distributions and fatigue parameters for 3 reinforced glass-ceramics (fluormica [FM], leucite [LR], and lithium disilicate [LD]) and a dense sintered yttrium-stabilized zirconia (YZ) were obtained from the literature and incorporated into the model...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28106935/effects-of-luting-composites-on-the-resultant-colors-of-ceramic-veneers-to-intended-shade-tab
#7
Qing Li
PURPOSE: To investigate the color differences of ceramic veneers and the intended shade tab, and evaluate the effects of luting composites on the resultant colors of ceramic veneers. MATERIALS AND METHODS: Pressable leucite-reinforced feldspathic ceramic discs (IPS e.max), with nominal shade A3, were fabricated with thicknesses of 1.0 mm, 0.7 mm, and 0.5 mm (n = 10/ thickness). The ceramic specimens were cemented onto a composite background (shade Dentin) using a veneer adhesive system with five colors of luting composites (RelyX)...
January 20, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28106229/the-rm-pressfit-vitamys-5-year-swiss-experience-of-the-first-100-cups
#8
Michael Wyatt, Jan Weidner, Dominik Pfluger, Martin Beck
BACKGROUND: The RM Pressfit vitamys is a titanium particle-coated monoblock cup with vitamin E stabilised highly cross-linked polyethylene. Initial fixation is achieved via press-fit with subsequent stability by bone on-growth. This is the first study to report the 5-year results of this design. METHODS: We performed a prospective cohort study according to STROBE guidelines of 100 consecutive total hip replacements (THRs) in 92 patients all with ceramic heads. Demographic data, pre/postoperative visual analogue scale (VAS) for pain and satisfaction, Harris Hip Scores (HHS) and complications were recorded...
January 20, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28106165/effects-of-sr-ht-gahnite-on-osteogenesis-and-angiogenesis-by-adipose-derived-stem-cells-for-critical-sized-calvarial-defect-repair
#9
Guifang Wang, Seyed-Iman Roohani-Esfahani, Wenjie Zhang, Kaige Lv, Guangzheng Yang, Xun Ding, Derong Zou, Daxiang Cui, Hala Zreiqat, Xinquan Jiang
Tissue engineering strategies to construct vascularized bone grafts are now attracting much attention. Strontium-hardystonite-Gahnite (Sr-HT-Gahnite) is a strong, highly porous, and biocompatible calcium silicate based bio-ceramic that contains strontium and zinc ions. Adipose derived stem cells (ASCs) have been demonstrated to have the ability in promoting osteogenesis and angiogenesis. In this study, the effects of Sr-HT-Gahnite on cell morphology, cell proliferation, and osteogenic differentiation of ASCs were systematically investigated...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28106140/gradient-hierarchic-aligned-porosity-sioc-ceramics
#10
Cekdar Vakifahmetoglu, Damla Zeydanli, Murilo Daniel de Mello Innocentini, Fernanda Dos Santos Ribeiro, Paulo Renato Orlandi Lasso, Gian Domenico Soraru
This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom of molds promoted the nucleation, expansion and rising of gas bubbles, and the creation of a ceramic matrix with axially oriented channels interconnected by small round pores. The samples were analyzed by SEM, tomography, BET, water immersion porosimetry and permeation to gas flow...
January 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28104926/the-bending-stress-distribution-in-bilayered-and-graded-zirconia-based-dental-ceramics
#11
Douglas Fabris, Júlio C M Souza, Filipe S Silva, Márcio Fredel, Joana Mesquita-Guimarães, Yu Zhang, Bruno Henriques
The purpose of this study was to evaluate the biaxial flexural stresses in classic bilayered and in graded zirconia-feldspathic porcelain composites. A finite element method and an analytical model were used to simulate the piston-on-ring test and to predict the biaxial stress distributions across the thickness of the bilayer and graded zirconia-feldspathic porcelain discs. An axisymmetric model and a flexure formula of Hsueh et al. were used in the FEM and analytical analysis, respectively. Four porcelain thicknesses were tested in the bilayered discs...
July 2016: Ceramics International
https://www.readbyqxmd.com/read/28104468/composite-material-consisting-of-microporous-%C3%AE-tcp-ceramic-and-alginate-for-delayed-release-of-antibiotics
#12
Michael Seidenstuecker, Juergen Ruehe, Norbert P Suedkamp, Annerose Serr, Annette Wittmer, Marc Bohner, Anke Bernstein, Hermann O Mayr
OBJECTIVE: The aim of this study was to produce a novel composite of microporous β-TCP filled with alginate and Vancomycin (VAN) to prolong the release behavior of the antibiotic for up to 28 days. MATERIAL AND METHODS: Using the flow chamber developed by the group, porous ceramics in a directional flow were filled with alginates of different composition containing 50 mg/mL of antibiotics. After cross-linking the alginate with calcium ions, incubation took place in 10 mL double-distilled water for 4 weeks at 37 °C...
January 16, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28103747/failure-of-an-uncemented-thumb-carpometacarpal-joint-ceramic-prosthesis
#13
E Kollig, W Weber, D Bieler, A Franke
: Thumb carpometacarpal joint replacement is associated with high rates of loosening and failure. We present our results for an uncemented ceramic-ceramic total joint prosthesis with a reverse ball-and-socket design and bioactive coating. Between 2008 and 2012, 29 prostheses were inserted into 28 patients (mean age 63 years) with advanced osteoarthritis. After a mean period of 33 months (range 9-62), 26 patients (27 implants) were available for follow-up. Six months postoperatively, 50% of the patients had radiological evidence of early loosening...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28103275/a-theoretical-model-for-predicting-residual-stress-generation-in-fabrication-process-of-double-ceramic-layer-thermal-barrier-coating-system
#14
Yan Song, Weijie Wu, Feng Xie, Yilun Liu, Tiejun Wang
Residual stress arisen in fabrication process of Double-Ceramic-Layer Thermal Barrier Coating System (DCL-TBCs) has a significant effect on its quality and reliability. In this work, based on the practical fabrication process of DCL-TBCs and the force and moment equilibrium, a theoretical model was proposed at first to predict residual stress generation in its fabrication process, in which the temperature dependent material properties of DCL-TBCs were incorporated. Then, a Finite Element method (FEM) has been carried out to verify our theoretical model...
2017: PloS One
https://www.readbyqxmd.com/read/28102826/ceramic-particle-engulfment-by-fibroblasts-does-not-alter-at-all-cell-behavior
#15
Pierre-Antoine Faye, Olivier Roualdes, Fabrice Rossignol, Daniel Jean Hartmann, Alexis Desmoulière
Despite many studies, the impact of ceramic particles on cell behavior remains still unclear. The aim of the present study was to investigate the effects of ceramic nano-sized particles on fibroblastic cells. Fibroblasts (dermal fibroblasts freshly isolated from skin samples and WI26 fibroblastic cells) were cultured in monolayer in the presence of alumina or cerium-zirconia particles (��� 50 nm diameter) at two concentrations (100 or 500 ��g.mL-1). Fluorescent alumina particles were also used. Cell morphology, cytoplasmic ceramic incorporation using confocal and transmission electron microscopy, and migration using silicon insert, were analyzed...
January 19, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28102338/strengthening-of-ceramic-based-artificial-nacre-via-synergistic-interactions-of-1d-vanadium-pentoxide-and-2d-graphene-oxide-building-blocks
#16
Andrea Knöller, Christian P Lampa, Felix von Cube, Tingying Helen Zeng, David C Bell, Mildred S Dresselhaus, Zaklina Burghard, Joachim Bill
Nature has evolved hierarchical structures of hybrid materials with excellent mechanical properties. Inspired by nacre's architecture, a ternary nanostructured composite has been developed, wherein stacked lamellas of 1D vanadium pentoxide nanofibres, intercalated with water molecules, are complemented by 2D graphene oxide (GO) nanosheets. The components self-assemble at low temperature into hierarchically arranged, highly flexible ceramic-based papers. The papers' mechanical properties are found to be strongly influenced by the amount of the integrated GO phase...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28102327/super-strong-materials-for-temperatures-exceeding-2000%C3%A2-%C3%A2-c
#17
Laura Silvestroni, Hans-Joachim Kleebe, William G Fahrenholtz, Jeremy Watts
Ceramics based on group IV-V transition metal borides and carbides possess melting points above 3000 °C, are ablation resistant and are, therefore, candidates for the design of components of next generation space vehicles, rocket nozzle inserts, and nose cones or leading edges for hypersonic aerospace vehicles. As such, they will have to bear high thermo-mechanical loads, which makes strength at high temperature of great importance. While testing of these materials above 2000 °C is necessary to prove their capabilities at anticipated operating temperatures, literature reports are quite limited...
January 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28100862/-bone-flap-resorption-after-cranioplasty-in-pediatric-patients-report-of-2-cases
#18
Rintaro Yokoyama, Takeshi Mikami, Shouhei Noshiro, Kei Miyata, Kentaro Toyama, Katsuya Komatsu, Noriaki Kikuchi, Tadashi Hasegawa, Nobuhiro Mikuni
Aseptic bone flap resorption, a rare complication after cranioplasty following decompressive craniectomy, is more likely to develop in children. We experienced two cases of aseptic bone flap resorption and identified potential pathophysiological mechanisms through histological findings. In the first case, an 11-year-old girl underwent decompressive craniectomy due to brain swelling with contusion. An autologous bone flap was cryopreserved for four months. Twenty-five months after cranioplasty with autologous bone flap, aseptic bone flap resorption was observed, and cranioplasty was performed with ceramic bone...
January 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28097927/assessment-and-comparison-of-three-high-aluminum-fly-ash-utilization-scenarios-in-inner-mongolia-china-using-an-eco-efficiency-indicator
#19
Shuo Yang, Ling Lin, Shao Peng Li, Qiang Li, Xiu Teng Wang, Liang Sun
Utilization of fly ash is of great importance in China in the context of resource and environmental crises. Different fly ash utilization processes are proposed, and some have been practically applied. However, none of these fly ash utilization pathways has been evaluated comprehensively by integrating both environmental and economic perspectives. In this study, three high-aluminum fly ash utilization methods in Mongolia were assessed and compared based on the concept of eco-efficiency. The environmental assessment was conducted in accordance with life-cycle assessment principles, and a monetization-weighting approach was applied to obtain social willingness-to-pay as a reflection of environmental impact...
January 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28097117/cobalt-intoxication-heart-failure-after-revision-total-hip-replacement-for-ceramic-head-fracture-a-case-report
#20
Chul-Ho Kim, Young Hyun Choi, Mi Yeon Jeong, Jae Suk Chang, Pil Whan Yoon
In 1960s, toxic heart failure due to cobalt poisoning was firstly reported from Canadian industrial worker. Following development of bearing materials in hip arthroplasties, using cobalt-chrome alloy in bearing surface, there were rarely reported of systemic affect toxic cobaltism include toxic heart failure due to articulation wear in Western countries. It could be happened more easily by third body wear from ceramic particle especially revision total hip replacement (THR) surgery using cobalt-chrome alloy following ceramic articulation breakage which index surgery performed by ceramic on ceramic bearing...
December 2016: Hip & Pelvis
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