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https://www.readbyqxmd.com/read/28894479/the-european-multicentre-bronchiectasis-audit-and-research-collaboration-embarc-experiences-from-a-successful-ers-clinical-research-collaboration
#1
REVIEW
James D Chalmers, Megan Crichton, Pieter C Goeminne, Michael R Loebinger, Charles Haworth, Marta Almagro, Montse Vendrell, Anthony De Soyza, Raja Dhar, Lucy Morgan, Francesco Blasi, Stefano Aliberti, Jeanette Boyd, Eva Polverino
In contrast to airway diseases like chronic obstructive pulmonary disease or asthma, and rare diseases such as cystic fibrosis, there has been little research and few clinical trials in bronchiectasis. Guidelines are primarily based on expert opinion and treatment is challenging because of the heterogeneous nature of the disease. In an effort to address decades of underinvestment in bronchiectasis research, education and clinical care, the European Multicentre Bronchiectasis Audit and Research Collaboration (EMBARC) was established in 2012 as a collaborative pan-European network to bring together bronchiectasis researchers...
September 2017: Breathe
https://www.readbyqxmd.com/read/28892934/why-do-patients-undergoing-chronic-obstructive-pulmonary-disease-treatment-turn-defaulters-a-follow-up-study-in-a-tertiary-care-hospital-in-jamnagar-india
#2
Amrita Sarkar, Abhay Javia, Pradeep Pithadia, Dipesh Parmar
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD), a progressive respiratory illness requiring long-term treatment, is a significant cause of morbidity, mortality and economic burden on the family as well as the country. In the tertiary health care facility where the study was carried out, it was observed that many COPD patients did not come for regular follow up. In these patients, treatment interruption may lead to increased morbidity and mortality. AIM: This study aimed to find out the reasons for defaulting follow up and treatment in COPD patients...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889106/prevention-of-copd-exacerbations-a-european-respiratory-society-american-thoracic-society-guideline
#3
Jadwiga A Wedzicha, Peter M A Calverley, Richard K Albert, Antonio Anzueto, Gerard J Criner, John R Hurst, Marc Miravitlles, Alberto Papi, Klaus F Rabe, David Rigau, Pawel Sliwinski, Thomy Tonia, Jørgen Vestbo, Kevin C Wilson, Jerry A Krishnan
This document provides clinical recommendations for the prevention of chronic obstructive pulmonary disease (COPD) exacerbations. It represents a collaborative effort between the European Respiratory Society and the American Thoracic Society.Comprehensive evidence syntheses were performed to summarise all available evidence relevant to the Task Force's questions. The evidence was appraised using the Grading of Recommendations, Assessment, Development and Evaluation approach and the results were summarised in evidence profiles...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28885968/diagnosing-chronic-obstructive-pulmonary-disease-among-afghanistan-and-iraq-veterans-veterans-affair-s-concordance-with-clinical-guidelines-for-spirometry-administration
#4
Aaron I Schneiderman, Deborah D Dougherty, Vincent P Fonseca, Charles L Wolters, Robert M Bossarte, Mehrdad Arjomandi
BACKGROUND: Early diagnosis and treatment of chronic obstructive pulmonary disease (COPD) can slow disease progression. The Department of Veterans Affairs (VA)/Department of Defense Clinical Practice Guidelines (CPG), established to improve patient outcomes, recommend the use of spirometry in the COPD diagnostic process. The aims of this study were to assess VA health care providers' performance related to CPG-recommended spirometry administration in the evaluation of newly diagnosed COPD among veterans, determine the patient characteristics that may influence the adherence rate, and compare VA concordance rates to those of other health plans...
September 2017: Military Medicine
https://www.readbyqxmd.com/read/28883469/characteristics-of-newly-diagnosed-copd-patients-treated-with-triple-inhaled-therapy-by-general-practitioners-a-real-world-italian-study
#5
Fabiano Di Marco, Pierachille Santus, Silvia Terraneo, Elena Peruzzi, Elisa Muscianisi, Claudio Ripellino, Valeria Pegoraro
Factors predicting prescriptions of triple therapy were investigated in a large group of general practitioners in Italy. In the population treated by identified general practitioners, a cohort of newly diagnosed chronic obstructive pulmonary disease patients was extracted from IMS Health Longitudinal Database during the period 2010-2013. From the diagnosis, 1-year follow-up was evaluated. Thirty-two thousand forty-six newly diagnosed chronic obstructive pulmonary disease patients were evaluated (57.7% male, mean age 67 years)...
September 7, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28882909/effect-of-time-and-day-of-admission-on-hospital-care-quality-for-patients-with-chronic-obstructive-pulmonary-disease-exacerbation-in-england-and-wales-single-cohort-study
#6
Christopher Michael Roberts, Derek Lowe, Emma Skipper, Michael C Steiner, Rupert Jones, Colin Gelder, John R Hurst, Gillian E Lowrey, Catherine Thompson, Robert A Stone
OBJECTIVE: To evaluate if observed increased weekend mortality was associated with poorer quality of care for patients admitted to hospital with chronic obstructive pulmonary disease (COPD) exacerbation. DESIGN: Prospective case ascertainment cohort study. SETTING: 199 acute hospitals in England and Wales, UK. PARTICIPANTS: Consecutive COPD admissions, excluding subsequent readmissions, from 1 February to 30 April 2014 of whom 13 414 cases were entered into the study...
September 6, 2017: BMJ Open
https://www.readbyqxmd.com/read/28878523/transcultural-adaptation-and-validation-of-the-korean-version-of-the-brief-illness-perception-questionnaire-for-patients-with-pulmonary-tuberculosis
#7
Jinsoo Min, Youjin Chang, Ki Man Lee, Kang Hyeon Choe, Jin Young An
BACKGROUND AND AIM: The brief illness perception questionnaire (BIPQ) has been used in many populations for both adults and children, and it provides a rapid assessment of illness perception. This study was performed to create a translated version of the BIPQ to fit the Korean society and to test its validity through pulmonary tuberculosis (TB) patients. METHODS: Translation and transcultural adaptation of BIPQ, applicable to the Korean society, was performed in accordance with the international guidelines...
July 2017: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/28874610/the-2017-global-initiative-for-chronic-obstructive-lung-disease-report-and-practice-implications-for-the-respiratory-therapist
#8
Michael W Hess
Since 1998, the Global Initiative for Obstructive Lung Disease (GOLD) has worked with health care professionals, medical researchers, and public health officials around the world to optimize the prevention, treatment, and management of COPD. GOLD has continually worked to ensure COPD management strategy recommendations are aligned with current published research. The 2017 GOLD report represents a major revision to GOLD strategy guidelines, the first such major revision in the last 5 years. As such, the 2017 report has significant implications for the diagnosis of COPD, the management of stable disease, and the treatment of exacerbations...
September 5, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28872442/added-value-of-computer-aided-ct-image-features-for-early-lung-cancer-diagnosis-with-small-pulmonary-nodules-a-matched-case-control-study
#9
Peng Huang, Seyoun Park, Rongkai Yan, Junghoon Lee, Linda C Chu, Cheng T Lin, Amira Hussien, Joshua Rathmell, Brett Thomas, Chen Chen, Russell Hales, David S Ettinger, Malcolm Brock, Ping Hu, Elliot K Fishman, Edward Gabrielson, Stephen Lam
Purpose To test whether computer-aided diagnosis (CAD) approaches can increase the positive predictive value (PPV) and reduce the false-positive rate in lung cancer screening for small nodules compared with human reading by thoracic radiologists. Materials and Methods A matched case-control sample of low-dose computed tomography (CT) studies in 186 participants with 4-20-mm noncalcified lung nodules who underwent biopsy in the National Lung Screening Trial (NLST) was selected. Variables used for matching were age, sex, smoking status, chronic obstructive pulmonary disease status, body mass index, study year of the positive screening test, and screening results...
September 5, 2017: Radiology
https://www.readbyqxmd.com/read/28866396/estimating-premature-mortality-attributable-to-pm2-5-exposure-and-benefit-of-air-pollution-control-policies-in-china-for-2020
#10
Kamal Jyoti Maji, Anil Kumar Dikshit, Mohit Arora, Ashok Deshpande
In past decade of rapid industrial development and urbanization, China has witnessed increasingly persistent severe haze and smog episodes, posing serious health hazards to the Chinese population, especially in densely populated cities. Quantification of health impacts attributable to PM2.5 (particulates with aerodynamic diameter≤2.5μm) has important policy implications to tackle air pollution. The Chinese national monitoring network has recently included direct measurements of ground level PM2.5, providing a potentially more reliable source for exposure assessment...
August 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28860265/official-ers-ats-clinical-practice-guidelines-noninvasive-ventilation-for-acute-respiratory-failure
#11
Bram Rochwerg, Laurent Brochard, Mark W Elliott, Dean Hess, Nicholas S Hill, Stefano Nava, Paolo Navalesi, Massimo Antonelli, Jan Brozek, Giorgio Conti, Miquel Ferrer, Kalpalatha Guntupalli, Samir Jaber, Sean Keenan, Jordi Mancebo, Sangeeta Mehta, Suhail Raoof
Noninvasive mechanical ventilation (NIV) is widely used in the acute care setting for acute respiratory failure (ARF) across a variety of aetiologies. This document provides European Respiratory Society/American Thoracic Society recommendations for the clinical application of NIV based on the most current literature.The guideline committee was composed of clinicians, methodologists and experts in the field of NIV. The committee developed recommendations based on the GRADE (Grading, Recommendation, Assessment, Development and Evaluation) methodology for each actionable question...
August 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28858010/is-there-a-role-for-inhaled-anticholinergic-therapy-in-asthma-management
#12
Shannon M Parkey, Cortney M Mospan
Anticholinergic therapy has long been a cornerstone of management of chronic obstructive pulmonary disease (COPD) but has not been included in treatment guidelines for asthma. In September 2015, tiotropium bromide was approved for use in adults with asthma; the indication has since been expanded to children ages 6 years and older. This article discusses appropriate patient selection and dosing, and the role of tiotropium bromide in asthma management.
September 2017: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/28851860/a-qualitative-study-of-gp-nurse-and-practice-manager-views-on-using-targeted-case-finding-to-identify-patients-with-copd-in-primary-care
#13
Rachael H Summers, Taniya Sharmeen, Kate Lippiett, Kate Gillett, Carla Astles, Linh Vu, Mark Stafford-Watson, Anne Bruton, Mike Thomas, Tom Wilkinson
'Finding the missing millions' with chronic obstructive pulmonary disease became part of the Department of Health strategy for England in 2010. Targeted case-finding within primary care is one potential pro-active strategy, but currently little is known about the views of healthcare professionals on this approach. In this study, 36 healthcare professionals (12 GPs, 14 nurses, and 10 practice managers) from 34 UK practices participated in semi-structured telephone interviews about targeted case-finding. Interviews followed an interview guide, were audio-recorded, transcribed verbatim, coded and analysed using 'Framework Approach'...
August 29, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28845472/a-clinical-prediction-score-to-guide-referral-of-elderly-dialysis-patients-for-kidney-transplant-evaluation
#14
Ling-Xin Chen, Michelle A Josephson, Donald Hedeker, Kellie Hunter Campbell, Nicole Stankus, Milda R Saunders
INTRODUCTION: Dialysis patients aged ≥70 years derive improved life expectancy through kidney transplantation compared to their waitlisted counterparts, but guidelines are not clear about how to identify appropriate transplantation candidates. We developed a clinical prediction score to identify elderly dialysis patients with expected 5-year survival appropriate for kidney transplantation (>5 years). METHODS: Incident dialysis patients in 2006-2009 aged ≥70 were identified from the United States Renal Data System database and divided into derivation and validation cohorts...
July 2017: KI Reports
https://www.readbyqxmd.com/read/28804700/abridged-version-of-the-awmf-guideline-for-the-medical-clinical-diagnostics-of-indoor-mould-exposure-s2k-guideline-of-the-german-society-of-hygiene-environmental-medicine-and-preventive-medicine-ghup-in-collaboration-with-the-german-association-of-allergists
#15
Gerhard A Wiesmüller, Birger Heinzow, Ute Aurbach, Karl-Christian Bergmann, Albrecht Bufe, Walter Buzina, Oliver A Cornely, Steffen Engelhart, Guido Fischer, Thomas Gabrio, Werner Heinz, Caroline E W Herr, Jörg Kleine-Tebbe, Ludger Klimek, Martin Köberle, Herbert Lichtnecker, Thomas Lob-Corzilius, Rolf Merget, Norbert Mülleneisen, Dennis Nowak, Uta Rabe, Monika Raulf, Hans Peter Seidl, Jens-Oliver Steiß, Regine Szewszyk, Peter Thomas, Kerttu Valtanen, Julia Hurraß
This article is an abridged version of the AWMF mould guideline "Medical clinical diagnostics of indoor mould exposure" presented in April 2016 by the German Society of Hygiene, Environmental Medicine and Preventive Medicine (Gesellschaft für Hygiene, Umweltmedizin und Präventivmedizin, GHUP), in collaboration with the above-mentioned scientific medical societies, German and Austrian societies, medical associations and experts. Indoor mould growth is a potential health risk, even if a quantitative and/or causal relationship between the occurrence of individual mould species and health problems has yet to be established...
2017: Allergo Journal International
https://www.readbyqxmd.com/read/28801434/comparative-effectiveness-of-six-chinese-herb-formulas-for-acute-exacerbation-of-chronic-obstructive-pulmonary-disease-protocol-for-systematic-review-and-network-meta-analysis
#16
Shaonan Liu, Jing Chen, Yihan He, Lei Wu, Jiaqi Lai, Jinhong Zuo, Lihong Yang, Xinfeng Guo
INTRODUCTION: Chinese medicine is commonly used to combine with pharmacotherapy for the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Six Chinese herb formulas involving Weijing decoction, Maxingshigan decoction, Yuebijiabanxia decoction, Qingqihuatan decoction, Dingchuan decoction and Sangbaipi decoction are recommended in Chinese medicine clinical guideline or textbook, to relieve patients with phlegm-heat according to Chinese syndrome differentiation...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28790283/-postoperative-atelectasis-and-pneumonia-after-general-thoracic-surgery
#17
Yasushi Hoshikawa, Daisuke Tochii
Atelectasis and pneumonia are common postoperative complications occurred in patients undergoing general thoracic surgery. Strategies to reduce the risk of postoperative pulmonary complications including these 2 disorders consist of smoking cessation, optimization of underlying chronic obstructive pulmonary disease( COPD), adequate pain control, intensive oral care, and so on. Preoperative treatments for patients with COPD are the same as those for COPD patients being not about to have surgery, which mainly consist of long-acting bronchodilators and pulmonary rehabilitation...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28774205/effect-of-respiratory-rehabilitation-techniques-on-the-autonomic-function-in-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review
#18
Jibril Mohammed, Hellen Da Silva, Jessica Van Oosterwijck, Patrick Calders
Patients with chronic obstructive pulmonary disease (COPD) show several extrapulmonary abnormalities such as impairment in the autonomic function (AF). Similarly, the use of respiratory training techniques such as controlled breathing techniques, noninvasive mechanical ventilation (NIMV), and oxygen supplementation for AF modulation in patients with COPD is popular in existing literature. However, the evidence to support their use is nonexistent. A systematic search of studies reporting on the effect of controlled breathing techniques, NIMV, and/or oxygen supplementation techniques on AF outcome parameters was conducted in three online databases: PubMed, Embase, and Web of Science...
August 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28774202/physical-activity-sedentary-behaviour-and-sleep-in-copd-guidelines-a-systematic-review
#19
Hayley Lewthwaite, Tanja W Effing, Timothy Olds, Marie T Williams
OBJECTIVES: Physical activity, sedentary and sleep behaviours have strong associations with health. This systematic review aimed to identify how clinical practice guidelines (CPGs) for the management of chronic obstructive pulmonary disease (COPD) report specific recommendations and strategies for these movement behaviours. METHODS: A systematic search of databases (Medline, Scopus, CiNAHL, EMbase, Clinical Guideline), reference lists and websites identified current versions of CPGs published since 2005...
August 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28769553/clinical-utility-of-alpha-1-proteinase-inhibitor-in-the-management-of-adult-patients-with-severe-alpha-1-antitrypsin-deficiency-a-review-of-the-current-literature
#20
REVIEW
David G Parr, Beatriz Lara
Alpha-1 antitrypsin (AAT) functions primarily to inhibit neutrophil elastase, and its deficiency predisposes individuals to the development of chronic obstructive pulmonary disease (COPD). The putative protective serum concentration is generally considered to be above a threshold of 11 μM/L, and therapeutic augmentation of AAT above this value is believed to retard the progression of emphysema. Several AAT preparations, all derived from human donor plasma, have been commercialized since approval by the US Food and Drug Administration (FDA) in 1987...
2017: Drug Design, Development and Therapy
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