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Maytenus laevis

Hiroyuki Nakagawa, Yoshihisa Takaishi, Yoshinori Fujimoto, Carmenza Duque, Cristina Garzon, Mitsunobu Sato, Masato Okamoto, Tetsuya Oshikawa, Sharif Uddin Ahmed
The methanol extract of the bark of the Colombian medicinal plant Maytenus laevis gave six new compounds and 28 known compounds. The structures of the new and known compounds were elucidated on the basis of spectroscopic evidence. Several of these compounds were screened for cytokine-inducing activity on human PBMCs to investigate antitumor effects, and canophyllol (12) demonstrated the most effective induction of the cytokines.
November 2004: Journal of Natural Products
No abstract text is available yet for this article.
May 1964: Proceedings of the Society for Experimental Biology and Medicine
Piacente, Tommasi, Pizza
Two new sesquiterpene-pyridine alkaloids, laevisines A (1) and B (2), have been isolated from the bark of Maytenus laevis, along with seven known alkaloids (3-9). Their structures were elucidated by FABMS analysis and 1D and 2D NMR spectroscopy including DQF-COSY, HSQC, and HMBC.
January 1999: Journal of Natural Products
J G Gonzalez, G delle Monache, F delle Monache, G B Marini-Bettolò
In the high Amazonian basin a plant named chuchuasha, (or chuchuaso) is used in traditional medicine for several purposes in the form of an alcoholic extract. This plant, a Maytenus species, most probably Maytenus laevis, grows in the subandean region of the Amazonian basin (Peru, Ecuador, Colombia). Antitumor and anti-inflammatory properties were recently attributed to the extracts of the root bark of the plant. The composition of the extract of M. laevis from the Putumayo area of Colombia was studied in order to establish the active principle responsible for these activities...
January 1982: Journal of Ethnopharmacology
K Flemming
No abstract text is available yet for this article.
June 1965: Die Naturwissenschaften
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