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https://www.readbyqxmd.com/read/27810802/body-diffusion-weighted-imaging-using-non-cpmg-fast-spin-echo
#1
Eric Gibbons, Patrick Le Roux, Shreyas Vasanawala, John Pauly, Adam Kerr
SS-FSE is a fast technique that does not suffer from off-resonance distortions to the degree that EPI does. Unlike EPI, SS-FSE is ill-suited to diffusion weighted imaging (DWI) due to the Carr-Purcell-Meiboom-Geill (CPMG) condition. Non- CPMG phase cycling does accommodate SS-FSE and DWI but places constraints on reconstruction, which are resolved here through parallel imaging. Additionally, improved echo stability can be achieved by using short duration and highly selective DIVERSE radiofrequency pulses. Here, signal-to-noise ratio (SNR) comparisons between EPI and nCPMG SS-FSE acquisitions and reconstruction techniques give similar values...
October 27, 2016: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/27738994/human-subcortical-brain-asymmetries-in-15-847-people-worldwide-reveal-effects-of-age-and-sex
#2
Tulio Guadalupe, Samuel R Mathias, Theo G M vanErp, Christopher D Whelan, Marcel P Zwiers, Yoshinari Abe, Lucija Abramovic, Ingrid Agartz, Ole A Andreassen, Alejandro Arias-Vásquez, Benjamin S Aribisala, Nicola J Armstrong, Volker Arolt, Eric Artiges, Rosa Ayesa-Arriola, Vatche G Baboyan, Tobias Banaschewski, Gareth Barker, Mark E Bastin, Bernhard T Baune, John Blangero, Arun L W Bokde, Premika S W Boedhoe, Anushree Bose, Silvia Brem, Henry Brodaty, Uli Bromberg, Samantha Brooks, Christian Büchel, Jan Buitelaar, Vince D Calhoun, Dara M Cannon, Anna Cattrell, Yuqi Cheng, Patricia J Conrod, Annette Conzelmann, Aiden Corvin, Benedicto Crespo-Facorro, Fabrice Crivello, Udo Dannlowski, Greig I de Zubicaray, Sonja M C de Zwarte, Ian J Deary, Sylvane Desrivières, Nhat Trung Doan, Gary Donohoe, Erlend S Dørum, Stefan Ehrlich, Thomas Espeseth, Guillén Fernández, Herta Flor, Jean-Paul Fouche, Vincent Frouin, Masaki Fukunaga, Jürgen Gallinat, Hugh Garavan, Michael Gill, Andrea Gonzalez Suarez, Penny Gowland, Hans J Grabe, Dominik Grotegerd, Oliver Gruber, Saskia Hagenaars, Ryota Hashimoto, Tobias U Hauser, Andreas Heinz, Derrek P Hibar, Pieter J Hoekstra, Martine Hoogman, Fleur M Howells, Hao Hu, Hilleke E Hulshoff Pol, Chaim Huyser, Bernd Ittermann, Neda Jahanshad, Erik G Jönsson, Sarah Jurk, Rene S Kahn, Sinead Kelly, Bernd Kraemer, Harald Kugel, Jun Soo Kwon, Herve Lemaitre, Klaus-Peter Lesch, Christine Lochner, Michelle Luciano, Andre F Marquand, Nicholas G Martin, Ignacio Martínez-Zalacaín, Jean-Luc Martinot, David Mataix-Cols, Karen Mather, Colm McDonald, Katie L McMahon, Sarah E Medland, José M Menchón, Derek W Morris, Omar Mothersill, Susana Munoz Maniega, Benson Mwangi, Takashi Nakamae, Tomohiro Nakao, Janardhanan C Narayanaswaamy, Frauke Nees, Jan E Nordvik, A Marten H Onnink, Nils Opel, Roel Ophoff, Marie-Laure Paillère Martinot, Dimitri Papadopoulos Orfanos, Paul Pauli, Tomáš Paus, Luise Poustka, Janardhan Yc Reddy, Miguel E Renteria, Roberto Roiz-Santiáñez, Annerine Roos, Natalie A Royle, Perminder Sachdev, Pascual Sánchez-Juan, Lianne Schmaal, Gunter Schumann, Elena Shumskaya, Michael N Smolka, Jair C Soares, Carles Soriano-Mas, Dan J Stein, Lachlan T Strike, Roberto Toro, Jessica A Turner, Nathalie Tzourio-Mazoyer, Anne Uhlmann, Maria Valdés Hernández, Odile A van den Heuvel, Dennis van der Meer, Neeltje E M van Haren, Dick J Veltman, Ganesan Venkatasubramanian, Nora C Vetter, Daniella Vuletic, Susanne Walitza, Henrik Walter, Esther Walton, Zhen Wang, Joanna Wardlaw, Wei Wen, Lars T Westlye, Robert Whelan, Katharina Wittfeld, Thomas Wolfers, Margaret J Wright, Jian Xu, Xiufeng Xu, Je-Yeon Yun, JingJing Zhao, Barbara Franke, Paul M Thompson, David C Glahn, Bernard Mazoyer, Simon E Fisher, Clyde Francks
The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still controversial. Here we present the largest ever analysis of subcortical brain asymmetries, in a harmonized multi-site study using meta-analysis methods. Volumetric asymmetry of seven subcortical structures was assessed in 15,847 MRI scans from 52 datasets worldwide. There were sex differences in the asymmetry of the globus pallidus and putamen...
October 13, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27452954/comparative-analysis-of-biologic-versus-synthetic-mesh-outcomes-in-contaminated-hernia-repairs
#3
Arnab Majumder, Joshua S Winder, Yuxiang Wen, Eric M Pauli, Igor Belyansky, Yuri W Novitsky
BACKGROUND: Contaminated operative fields pose significant challenges for surgeons performing ventral hernia repair. Although biologic meshes have been utilized increasingly in these fields, recent evidence suggests that synthetic meshes represent a viable option. We analyzed the outcomes of biologic and synthetic mesh utilized in patients undergoing major ventral hernia repair in clean-contaminated/contaminated fields. METHODS: We conducted a multicenter, retrospective review of patients undergoing open ventral hernia repair in clean-contaminated/contaminated fields using biologic or synthetic mesh...
October 2016: Surgery
https://www.readbyqxmd.com/read/27375649/nod-factor-effects-on-root-hair-specific-transcriptome-of-medicago-truncatula-focus-on-plasma-membrane-transport-systems-and-reactive-oxygen-species-networks
#4
Isabelle Damiani, Alice Drain, Marjorie Guichard, Sandrine Balzergue, Alexandre Boscari, Jean-Christophe Boyer, Véronique Brunaud, Sylvain Cottaz, Corinne Rancurel, Martine Da Rocha, Cécile Fizames, Sébastien Fort, Isabelle Gaillard, Vincent Maillol, Etienne G J Danchin, Hatem Rouached, Eric Samain, Yan-Hua Su, Julien Thouin, Bruno Touraine, Alain Puppo, Jean-Marie Frachisse, Nicolas Pauly, Hervé Sentenac
Root hairs are involved in water and nutrient uptake, and thereby in plant autotrophy. In legumes, they also play a crucial role in establishment of rhizobial symbiosis. To obtain a holistic view of Medicago truncatula genes expressed in root hairs and of their regulation during the first hours of the engagement in rhizobial symbiotic interaction, a high throughput RNA sequencing on isolated root hairs from roots challenged or not with lipochitooligosaccharides Nod factors (NF) for 4 or 20 h was carried out...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27352787/differences-in-midline-fascial-forces-exist-following-laparoscopic-and-open-transversus-abdominis-release-in-a-porcine-model
#5
Joshua S Winder, Jerome Lyn-Sue, Allen R Kunselman, Eric M Pauli
INTRODUCTION: Posterior component separation herniorrhaphy via transversus abdominis release (TAR) permits midline reapproximation of large fascial defects. To date, no report delineates the reduction in tensile force to reapproximate midline fascia following TAR. We hypothesized that open and laparoscopic TAR would provide similar reductions in midline reapproximation forces in a porcine model. METHODS: Under general anesthesia, a 20-cm midline laparotomy was created and bilateral lipocutaneous flaps were raised to expose the anterior rectus sheath...
June 28, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27352786/guidelines-for-privileging-and-credentialing-physicians-in-gastrointestinal-endoscopy
#6
Jonathan Pearl, Erika Fellinger, Brian Dunkin, Eric Pauli, Thadeus Trus, Jeffrey Marks, Robert Fanelli, Michael Meara, Dimitrios Stefanidis, William Richardson
No abstract text is available yet for this article.
August 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27351652/colonoscopic-assisted-percutaneous-endoscopic-gastrostomy-tube-placement
#7
Ryan M Juza, Joshua S Winder, Eric M Pauli
No abstract text is available yet for this article.
June 28, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27338580/reduced-postoperative-pain-scores-and-narcotic-use-favor-per-oral-endoscopic-myotomy-over-laparoscopic-heller-myotomy
#8
Salvatore Docimo, Abraham Mathew, Alexander J Shope, Joshua S Winder, Randy S Haluck, Eric M Pauli
INTRODUCTION: Per-oral endoscopic myotomy (POEM) is a less invasive therapy for achalasia with a shorter hospitalization but with similar short- and long-term outcomes as a laparoscopic Heller myotomy (LHM). Previous literature comparing POEM to LHM has focused primarily on postoperative outcome parameters such as complications, dysphagia scores and gastro-esophageal reflux severity. This study specifically compares postoperative pain following POEM to pain following LHM, the current gold-standard operation...
June 23, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27152591/reply-posterior-component-separation-with-transversus-abdominis-release-technique-utility-and-outcomes-in-complex-abdominal-wall-reconstruction
#9
Christine M Jones, Joshua S Winder, John D Potochny, Eric M Pauli
No abstract text is available yet for this article.
September 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27139705/changing-attitudes-and-improving-skills-demonstrating-the-value-of-the-sages-flexible-endoscopy-course-for-fellows
#10
Aimee K Gardner, Jeffrey M Marks, Eric M Pauli, Arnab Majumder, Brian J Dunkin
BACKGROUND: The purpose of this study was to examine the effectiveness of the SAGES flexible endoscopy course in improving fellows' attitudes, confidence, and skills related to implementing endoscopy in practice. METHODS: Fellows participated in a 2-day course consisting of case presentations, expert panels, and hands-on laboratory training. Before and after the course, fellows completed a questionnaire assessing demographics, experiences in residency, practice plans, plans to implement flexible endoscopy in practice, and level of confidence performing 15 endoscopic procedures...
May 2, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27107825/transversus-abdominis-release-for-abdominal-wall-reconstruction-early-experience-with-a-novel-technique
#11
Joshua S Winder, Brittany J Behar, Ryan M Juza, John Potochny, Eric M Pauli
BACKGROUND: Ventral hernias are common sequelae of abdominal surgery. Recently, transversus abdominis release has emerged as a viable option for large or recurrent ventral hernias. Our objective was to determine the outcomes of posterior component separation via transversus abdominis release for the treatment of abdominal wall hernias in the first series of patients at one institution. METHODS: We performed a retrospective review of a prospectively maintained database of open ventral hernia repair patients to identify patients who underwent posterior component separation via transversus abdominis release at one institution from 2012 to 2015...
August 2016: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/27023876/how-i-do-it-novel-parastomal-herniorrhaphy-utilizing-transversus-abdominis-release
#12
Eric M Pauli, Ryan M Juza, Joshua S Winder
INTRODUCTION: Parastomal hernias are a complex surgical problem affecting a large number of patients. Recurrences continue to occur despite various methods of repair. We present a novel method of open parastomal hernia repair with retromuscular mesh reinforcement in a modified Sugarbaker configuration. METHODS: A full mildline laparotomy is performed and all adhesions are taken down. We then perform an open parastomal hernia repair by utilizing retromuscular dissection, posterior component separation via transversus abdominis release, and lateralization of the bowel utilizing a modified Sugarbaker mesh configuration within the retromuscular space...
August 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/26994774/implementing-a-robotics-curriculum-at-an-academic-general-surgery-training-program-our-initial-experience
#13
Joshua S Winder, Ryan M Juza, Jennifer Sasaki, Ann M Rogers, Eric M Pauli, Randy S Haluck, Stephanie J Estes, Jerome R Lyn-Sue
The robotic surgical platform is being utilized by a growing number of hospitals across the country, including academic medical centers. Training programs are tasked with teaching their residents how to utilize this technology. To this end, we have developed and implemented a robotic surgical curriculum, and share our initial experience here. Our curriculum was implemented for all General Surgical residents for the academic year 2014-2015. The curriculum consisted of online training, readings, bedside training, console simulation, participating in ten cases as bedside first assistant, and operating at the console...
September 2016: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/26818302/posterior-component-separation-with-transversus-abdominis-release-technique-utility-and-outcomes-in-complex-abdominal-wall-reconstruction
#14
REVIEW
Christine M Jones, Joshua S Winder, John D Potochny, Eric M Pauli
BACKGROUND: Ventral hernia formation is a frequent and increasingly difficult problem. Nonmidline hernias, parastomal hernias, hernias near bony landmarks, and recurrent ventral hernias (especially after anterior component separation) present particular challenges. Typical reconstructive techniques may struggle to reestablish abdominal domain and to create a lasting repair. Posterior component separation with transversus abdominis release is a novel technique that offers a durable solution to a variety of complex ventral hernias...
February 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/26769409/multimodal-endoscopic-management-of-iatrogenic-transverse-colon-injuries-from-a-percutaneous-endoscopic-gastrostomy-tube
#15
Joshua S Winder, Ryan M Staszak, Eric M Pauli
No abstract text is available yet for this article.
June 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/26558911/laparoscopic-repair-of-a-left-sided-paraduodenal-hernia
#16
Joshua S Winder, Eric M Pauli, Randy S Haluck
INTRODUCTION: Internal hernias are a rare cause of bowel obstruction, constituting 0.2-0.9 % of all cases with paraduodenal hernias (PDH) being the most common accounting for 50 % of all internal hernias with 75 % of those being left-sided [1, 2]. They are due to small bowel herniating into a peritoneum-lined sac at the fourth portion of the duodenum as the result of abnormal midgut rotation during embryonic development. Patients may present with symptoms of small bowel obstruction, though the majority are found incidentally [3]...
August 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26482309/alkyl-amine-bevirimat-derivatives-are-potent-and-broadly-active-hiv-1-maturation-inhibitors
#17
Emiko Urano, Sherimay D Ablan, Rebecca Mandt, Gary T Pauly, Dina M Sigano, Joel P Schneider, David E Martin, Theodore J Nitz, Carl T Wild, Eric O Freed
Concomitant with the release of human immunodeficiency virus type 1 (HIV-1) particles from the infected cell, the viral protease cleaves the Gag polyprotein precursor at a number of sites to trigger virus maturation. We previously reported that a betulinic acid-derived compound, bevirimat (BVM), blocks HIV-1 maturation by disrupting a late step in protease-mediated Gag processing: the cleavage of the capsid-spacer peptide 1 (CA-SP1) intermediate to mature CA. BVM was shown in multiple clinical trials to be safe and effective in reducing viral loads in HIV-1-infected patients...
October 19, 2015: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/26416380/management-of-non-acute-gastrointestinal-defects-using-the-over-the-scope-clips-otscs-a-retrospective-single-institution-experience
#18
Joshua S Winder, Afif N Kulaylat, Jane R Schubart, Hassan M Hal, Eric M Pauli
INTRODUCTION: Advanced endoscopic techniques provide novel therapies for complications historically treated with surgical interventions. Over-the-scope clips (OTSCs) have recently been shown to be effective at endoscopic closure of gastrointestinal (GI) defects. We hypothesize that by following classic surgical principles of fistula management, a high rate of long-term success can be achieved with endoscopic closure of non-acute GI tract defects. METHODS: A retrospective review of a single-institution prospectively maintained database (2012-2015) of all patients referred for the management of GI leaks or fistulae who underwent attempted closure with the OTSC system (Ovesco, Germany) was performed...
June 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/26279553/adjusting-the-local-arrangement-of-%C3%AF-stacked-oligothiophenes-through-hydrogen-bonds-a-viable-route-to-promote-charge-transfer
#19
Hongguang Liu, Éric Brémond, Antonio Prlj, Jérôme F Gonthier, Clémence Corminboeuf
We show that substituting quaterthiophene cores with strong H-bond aggregators, such as urea groups, provides an efficient way to adjust the mutual in-plane displacements of the semiconducting units and promote charge transfer. Our 2-D structure-property mapping reveals that the insertion of substituents induces up to 2.0 Å longitudinal and transversal displacements between the π-conjugated moieties. Some of these relative displacements lead to improved cofacial orbital overlaps that are otherwise inaccessible due to Pauli repulsion...
July 3, 2014: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/26261782/quantitative-bi-component-t2-analysis-of-histologically-normal-achilles-tendons
#20
Eric Y Chang, Jiang Du, Sheronda Statum, Chantal Pauli, Christine B Chung
INTRODUCTION: the aim of this pilot study was to implement ultrashort echo time (UTE) MRI with bi-component analysis on grossly normal Achilles tendons with histologic correlation. MATERIALS AND METHODS: six tendon samples which were grossly normal on visual inspection and palpation were harvested. A 2D UTE pulse sequence was implemented on a 3T MR scanner and bi-component and single-component T2* analysis was performed. Tendon samples were histologically processed and evaluated...
April 2015: Muscles, Ligaments and Tendons Journal
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