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Adult Henoch-Scholein purpura

Michael J Goodman, James D Nordin, Edward A Belongia, John P Mullooly, James Baggs
BACKGROUND: We describe here a case of Henoch-Schönlein purpura (HSP) that occurred 10 days after administration of the meningococcal polysaccharide vaccine and came to the attention of a Vaccine Safety Datalink (VSD) investigator (but did not occur in the VSD cohort). Periodic case reports have linked vaccines to HSP. OBJECTIVE: To better understand the potential risk for HSP after immunization with the meningococcal polysaccharide vaccine. PATIENTS AND METHODS: We studied the VSD cohort to estimate the 42-day postvaccination incidence rate of HSP in the VSD population 16 to 20 years of age...
August 2010: Pediatrics
Seniz Ergin, Berna Sanli Erdoğan, Hüseyin Turgut, Deniz Evliyaoğlu, Ata Nevzat Yalçin
Henoch-Schölein purpura is usually a disease of children presenting with arthralgia, abdominal pain, renal involvement, and palpable purpura. Viral and bacterial infections may have a role in its etiology. We present a 32-year-old male patient with recurrent Henoch-Schölein purpura in association with a chronic hepatitis B infection of ten years duration. The patient had received lamuvidine and interferon-alpha for the treatment of hepatitis B infection for a year. The skin lesions disappeared with the treatment of the hepatitis B infection...
October 2005: Journal of Dermatology
A Watanabe, T Kakihara, M Hara, A Tanaka, K Kanno, C Imai, Y Ikarashi, S Okubo, T Yanagihara, M Uchiyama
BACKGROUND: To better understand the mechanisms of glomerular epithelial cell (GEC) injuries in various diseases, we compared GEC excreted during chemotherapy (antineoplastic drugs) and GEC excreted in renal diseases. METHODS: For 19 patients undergoing chemotherapy (85 courses), 69 patients with IgA nephropathy and 16 patients with Henoch-Schölein purpura nephritis, the number of excreted GEC and GEC casts were counted by an immunofluorescent study. The morphological features of GEC were also studied in an immunofluorescent study combined with Hoechst stain...
December 2001: Pediatrics International: Official Journal of the Japan Pediatric Society
I S Szer
The joint pain, inflammation, and painful cutaneous edema of Henoch-Schölein purpura (HSP) are effectively treated with analgesics, nonsteroidal anti-inflammatory agents, and corticosteroids, but the optimal management of HSP-associated gastrointestinal and renal involvement has not yet been determined. The results of mostly anecdotal and uncontrolled studies favor a short course of oral corticosteroids for severe abdominal pain and aggressive immunosuppressive therapy for patients with progressive HSP nephritis...
May 1999: Cleveland Clinic Journal of Medicine
B Roche, M Blazquez, A Charlier, J C Bognel
The authors report three cases of Scholein-Henoch's purpura in adults which were characterized by atypical severity of the digestive signs which led to laparotomy. In one case, the digestive signs preceded the onset of the cutaneous purpura, which made the diagnosis difficult. The digestive impact was confirmed endoscopically (petechia, ulceration, ulcerated stenosis) in two of the three patients. Damage of the small intestine predominated, as in the literature, but only one patient required resection of the intestine...
January 1994: Annales de Gastroentérologie et D'hépatologie
M Morichau-Beauchant, G Touchard, P Maire, M Briaud, P Babin, D Alcalay, C Matuchansky
An adult male patient with Henoch-Schônlein purpura and severe intestinal involvement is reported. Henoch-Schönlein purpura was documented by microscopic and immunofluorescent studies of the skin and kidney. At duodenojejunoscopy there were multiple ulcerations and thickening of mucosal folds. Microscopic and immunofluorescent studies of duodenum and proximal jejunum showed submucosal vasculitis and granular deposits of immunoglobulin A and complement components (C3) in the vessel walls, similar to those observed in the skin and kidney...
June 1982: Gastroenterology
S Kalowski, P Kincaid-Smith
No abstract text is available yet for this article.
1973: Perspectives in Nephrology and Hypertension
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