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https://www.readbyqxmd.com/read/28647750/misdiagnosed-paranasal-gossypiboma-a-10-year-experience-with-21-cases-at-a-tertiary-center
#1
P Z Wu, W Sun, Y H Wen, R Q Ma, X L Zhu, W P Wen
BACKGROUND: Different from rhinoliths, the paranasal gossypiboma is a foreign body, such as a surgical sponge, left in the nasal cavity. It is a rare, frequently misdiagnosed disease that has rarely been reported. We summarize its clinical characteristics, management, and possible risk factors. METHODOLOGY: We reviewed medical records of confirmed paranasal gossypibomas at a tertiary medical center between 2005 and 2015. Clinical symptoms, age, sex, anatomic sites, endoscopic photography, computed tomography, intraoperative findings, and past medical history were reviewed...
June 25, 2017: Rhinology
https://www.readbyqxmd.com/read/28647567/stearoyl-coa-desaturase-regulates-sorafenib-resistance-via-modulation-of-er-stress-induced-differentiation
#2
Mark Kin Fai Ma, Eunice Yuen Ting Lau, Doris Hoi Wing Leung, Jessica Lo, Nicole Pui Yu Ho, Lily Kwan Wai Cheng, Stephanie Ma, Chi Ho Lin, John A Copland, Jin Ding, Regina Cheuk Lam Lo, Irene Oi Lin Ng, Terence Kin Wah Lee
We investigated the functional role and clinical significance of Stearoyl CoA desaturase-1 (SCD1) mediated endoplasmic reticulum (ER) stress in regulation of liver tumor-initiating cells (T-ICs) and sorafenib resistance, aiming to develop a novel therapeutic strategy against hepatocellular carcinomas (HCCs) METHODS We evaluated the clinic-pathological relevance of SCD1 and its correlation with sorafenib resistance in large cohorts of HCC clinical samples by qPCR and immunohistochemical analyses. Lentiviral-based overexpression and knockdown approaches were performed to characterize functional roles of SCD1 in regulation of liver T-ICs and sorafenib resistance...
June 21, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28643303/-application-of-fascia-orientation-of-pelvic-autonomic-nerve-preservation-in-rectal-cancer-surgery
#3
Xiaobo Liang, Yi Wang, Guolong Ma
Rectal cancer has become the second most common gastrointestinal tumor in our country. With the development of comprehensive treatment, the long-term survival rate of patients with rectal cancer has greatly increased, meanwhile, higher postoperative quality of life is required. But the genitourinary dysfunction which is mainly caused by intraoperative pelvic autonomic nerve damage haunts postoperative rectal cancer patients. Traditional pelvic autonomic nerve protection technology born in the 1980s only improves urogenital function in a part of postoperative patients...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28643071/forgotten-biliary-stents-ignorance-is-not-bliss
#4
Saket Kumar, Abhijit Chandra, Rugved Kulkarni, Ajeet Pratap Maurya, Vishal Gupta
BACKGROUND: Endoscopic biliary stenting is a common procedure in routine gastroenterology practice. Plastic stents are the most common type of stents used and are indicated mainly for short-term biliary drainage. Prolonged indwelling plastic stents can result in disastrous complications. METHODS: We conducted a retrospective analysis of patients who presented with complications of forgotten biliary stents in a tertiary care hospital during January 2010 to October 2016...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28635352/a-randomized-controlled-trial-comparing-two-types-of-retractors-at-caesarean-delivery
#5
Abbey J Hardy-Fairbanks, Todd Mackenzie, Martin McCarthy, Marlene B Goldman, Michele R Lauria
The aim of this study was to determine if the use of a self-retaining, symmetrical retractor (OB/Mobius(®)) during caesarean delivery is associated with differences in post-operative pain experience. Consenting women undergoing caesarean delivery were randomly assigned to OB/Mobius(®) versus conventional retraction instruments. Women were blinded to retractor type and filled out surgical pain surveys each post-operative day. Additional outcome variables were collected through a provider survey and chart review...
June 21, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28628356/clips-versus-resilient-liners-used-with-bilateral-posterior-prefabricated-bars-for-retaining-four-implant-supported-mandibular-overdentures
#6
Mona Gibreel, Mohammed Fouad, Fatma El-Waseef, Nesma El-Amier, Hamdy Marzook
The objective of this research was to clinically compare peri-implant tissue health of bar-clips versus silicone-resilient liners used with bilateral posterior bars for retaining four implant supported mandibular overdentures. Thirty completely edentulous male patients (mean age 65) were randomly assigned into two equal groups. Each patient received four implants in canine and first molar regions of the mandible using flapless surgical technique. Mandibular overdentures were immediately connected to the implants with bilateral prefabricated instant adjusting bars...
June 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28622840/systematic-review-of-randomized-controlled-trials-on-the-role-of-coaching-in-surgery-to-improve-learner-outcomes
#7
REVIEW
Louise-Helene Gagnon, Nimrah Abbasi
BACKGROUND: Surgical coaching, with the goal of improving operative performance, has been introduced into residency and fellowship programs. This is the first systematic review on surgical coaching limited to randomized controlled trials. The objective of this review is to synthesize the existing evidence that addresses the following question: "What are the effects of surgical coaching to improve learner outcomes?" METHODS: A comprehensive literature search was performed through the following databases: MEDLINE, EMBASE, ERIC, and Cochrane Central Register of Controlled Trials...
June 13, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28622309/eyelid-and-fornix-reconstruction-in-abortive-cryptophthalmos-a-single-center-experience-over-12-years
#8
J Ding, Z Hou, Y Li, N Lu, D Li
PurposeAbortive cryptophthalmos is a rare congenital eyelid anomaly with poor prognosis for vision and cosmesis. The study aims to present its varied manifestations and surgical outcomes.Patients and methodsThe medical records of patients with abortive cryptophthalmos treated at the Oculoplastic Clinic of Beijing Tongren Hospital between January 2004 and May 2016 were reviewed. Early surgical intervention was performed when exposure keratopathy occurs. Upper eyelid and superior fornix were mainly reconstructed with sliding myocutaneous flap and scleral and amniotic grafts...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28621025/dorsal-root-ganglion-stimulation-as-a-salvage-treatment-for-complex-regional-pain-syndrome-refractory-to-dorsal-column-spinal-cord-stimulation-a-case-series
#9
Ajax Yang, Corey W Hunter
OBJECTIVE: The efficacy of traditional spinal cord stimulation (t-SCS) tends to decay over time in patients with complex regional pain syndrome (CRPS). While it has been shown that dorsal root ganglion (DRG) stimulation is extremely effective in t-SCS-naïve patients with CRPS, its efficacy in patients who had previously failed t-SCS is unknown. Given that DRG-SCS and t-SCS target different spinal pathways, a failure with t-SCS should not automatically preclude a patient from attempting DRG-SCS...
June 16, 2017: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/28619689/risks-and-benefits-of-opportunistic-salpingectomy-during-vaginal-hysterectomy-a-decision-analysis
#10
Lauren A Cadish, Jonathan P Shepherd, Emma L Barber, Beri Ridgeway
BACKGROUND: Fallopian tubes are commonly removed during laparoscopic and open hysterectomy to prevent ovarian and tubal cancer, but are not routinely removed during vaginal hysterectomy due to perceptions of increased morbidity, difficulty, or inadequate surgical training. OBJECTIVE: We sought to quantify complications and costs associated with a strategy of planned salpingectomy during vaginal hysterectomy. STUDY DESIGN: We created a decision analysis model using TreeAgePro...
June 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28607855/seri-surgical-scaffold-in-2-stage-breast-reconstruction-2-year-data-from-a-prospective-multicenter-trial
#11
Nolan Karp, Mihye Choi, David A Kulber, Susan Downey, Gloria Duda, Gabriel M Kind, Mark L Jewell, Diane K Murphy, Max R Lehfeldt, Neil Fine
BACKGROUND: Soft-tissue support devices are used during breast reconstruction. This study investigated long-term clinical data following SERI Surgical Scaffold (SERI) implantation, a bioresorbable, silk-derived scaffold for soft-tissue support. METHODS: This was a prospective, multicenter study in 103 subjects who received SERI during stage 1 of 2-stage breast reconstruction with subpectoral tissue expander placement (Natrelle Style 133V; Allergan plc, Dublin, Ireland) followed by subpectoral breast implant placement...
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28607014/np108-an-antimicrobial-polymer-with-activity-against-methicillin-and-mupirocin-resistant-staphylococcus-aureus
#12
Derry K Mercer, Laura K Katvars, Fiona Hewitt, Daniel W Smith, Jennifer Robertson, Deborah A O'Neil
Staphylococcus aureus is a clinically significant human pathogen that causes infectious diseases ranging from skin and soft tissue infections (SSTI), healthcare associated infections (HAI) to potentially fatal bacteraemia and endocarditis. Nasal carriage of S. aureus, especially persistent carriage, is associated with an increased risk of subsequent infection, particularly nosocomial and surgical site infections (SSI), usually via autoinfection. NP108 is a cationic antimicrobial polymer composed of Generally Recognized as Safe (GRAS) amino acid building blocks...
June 12, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28604375/retained-upper-third-molars-during-le-fort-i-osteotomy-with-downfracture
#13
Marco Friscia, Marzia Petrocelli, Carolina Sbordone, Raffaele Corvino, Fabio Maglitto, Francesco Maria Cassandro, Giorgio Iaconetta, Luigi Califano
AIM: The aim of our study is to demonstrate that the presence of upper wisdom teeth must be evaluated before and during Le Fort I osteotomy because attention must be focused to the disadvantages or facilitations of surgery depending on molar presence. MATERIALS OF STUDY: Our study has analyzed two groups, each one including 20 patients, 10 males and 10 females, with an age between 16-30 years. The first group was treated with le Fort I osteotomy leaving in situ the wisdom upper third molars...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28602926/radiation-induced-malignant-peripheral-nerve-sheath-tumors-a-systematic-review
#14
REVIEW
Ryuya Yamanaka, Azusa Hayano
OBJECTIVE: Radiation-induced malignant peripheral nerve sheath tumors (MPNSTs) are an uncommon late risk of irradiation. We conducted the largest systematic review to date, of individual patient data for patients with these tumors. METHODS: We conducted a systematic search using the PubMed database, and compiled a systematic literature review. We used Kaplan-Meier analysis and log-rank test to estimate survival. RESULTS: We analyzed 65 radiation-induced and 26 radiation-associated MPNSTs in patients with neurofibromatosis...
June 8, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28601898/varied-facets-of-rectal-atresia-and-rectal-stenosis
#15
Shilpa Sharma, Devendra K Gupta
Rectal atresia (RA) and rectal stenosis (RS) are rare anomalies with varied treatment options. A thorough literature review was done on reported cases/series of RA and RS. Based on evidence from cases managed over last 15 years, new insights into embryology were hypothesized. A comprehensive review was compiled with updated knowledge on diagnosis and management. RA is classified into five types I: II: III: IV: V as RS: RA with septal defect: RA with a fibrous cord between two atretic ends: RA with a gap: Multiple RA and/or RS...
June 10, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28601875/activities-of-mscs-derived-from-transgenic-mice-seeded-on-adm-scaffolds-in-wound-healing-and-assessment-by-advanced-optical-techniques
#16
Ning Wang, Hanping Liu, Xuefeng Li, Qilei Zhang, Maosheng Chen, Ying Jin, Xiaoyuan Deng
BACKGROUND/AIMS: Bone marrow Mesenchymal stem cells (MSCs) are promising for promoting cutaneous wound healing through reinforcing cellular processes. We evaluated the effect of GFP-tagged MSCs transplantation on skin regeneration in excisional wounds in mice. METHODS: MSCs from GFP-labeled transgenic mice were co-cultured with acellular dermal matrix (ADM) scaffolds, and MSC-ADM scaffolds were transplanted into surgical skin wounds of BALB/c mice. After implantation, the survival and behavior of MSCs were examined by second harmonic generation and two-photon excitation fluorescence imaging, western blotting and DNA amplification and sequencing...
June 9, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/28599977/fate-of-remnant-sinuses-of-valsalva-in-patients-with-bicuspid-and-trileaflet-valves-undergoing-aortic-valve-ascending-aorta-and-aortic-arch-replacement
#17
Rita Karianna Milewski, Andreas Habertheuer, Joseph E Bavaria, Mary Siki, Wilson Y Szeto, Eric Krause, Varun Korutla, Nimesh D Desai, Prashanth Vallabhajosyula
OBJECTIVE: In patients presenting with aortic valvulopathy with concomitant ascending aortic aneurysm, surgical management of the sinus of Valsalva segment remains undefined, especially for moderately dilated aortic roots. In patients with this pathology undergoing aortic valve replacement with supracoronary ascending aorta replacement, we assessed the fate of the remnant preserved sinus of Valsalva segment stratified by aortic valve morphology and pathology. METHODS: From 2002 to 2015, 428 patients underwent elective aortic valve replacement with supracoronary ascending aorta replacement...
April 28, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28599305/heptamethine-carbocyanine-dz-1-dye-for-near-infrared-fluorescence-imaging-of-hepatocellular-carcinoma
#18
Jiaze An, Ningning Zhao, Caiqin Zhang, Yong Zhao, Dengxu Tan, Ya Zhao, Bing Bai, Hai Zhang, Boyang Jason Wu, Changhong Shi
Nar-infrared fluorescence (NIRF) dyes have recently emerged as promising tools for non-invasive imaging of different types of cancers. Heree, we explored the potential utility of a NIRF DZ-1 dye, with dual imaging and tumour targeting functions, in hepatocellular carcinoma (HCC). We showed the preferential uptake of DZ-1 by HCC cells in vitro and in derived subcutaneous/orthotopic tumour xenografts, accompanied by a minimal effect on normal cells. DZ-1 simplified tumour growth profiling as well, since we were able to correlate NIRF signals with tumour volume and/or tumour-emitting luminescence in mice...
May 24, 2017: Oncotarget
https://www.readbyqxmd.com/read/28594739/posterior-vitrectorhexis-a-surgical-modification-for-intraocular-foreign-body-removal-through-limbal-route
#19
Prabu Baskaran, Sahil Bhandari, Madanagopalan V Govindarajan
PURPOSE: To describe a modified surgical technique of creating a posterior capsule opening for removal of retained intraocular foreign body, what we call as retroillumination-assisted posterior vitrectorhexis. METHODS: Vitrectomy probe through pars plana route is used to create a well-controlled circular posterior vitrectorhexis. RESULTS: A uniformly circular posterior capsule opening is created after standard pars plana vitrectomy for the removal of foreign body...
June 7, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28587977/combination-of-straight-and-tilted-implants-for-supporting-screw-retained-dental-prostheses-in-atrophic-posterior-maxillae-a-2-year-prospective-study
#20
Juan-Carlos Casar-Espinosa, Raquel Castillo-Oyagüe, María Ángeles Serrera-Figallo, Roberto Garrido-Serrano, Christopher D Lynch, Manuel Menéndez-Collar, Daniel Torres-Lagares, José-Luis Gutiérrez-Pérez
OBJECTIVES: To evaluate the two-year survival rate (SR) and marginal bone loss (MBL) of fixed dental prostheses (FDPs) supported by straight (S) and tilted (T) implants under the influence of diverse study variables. METHODS: A prospective investigation comprising 21 patients provided with a total of 27 maxillary screw-retained restorations fixed to 70 dental implants was developed. Two groups of implants were considered depending on their inclination with respect to the occlusal plane: Group 1 (S, n=37): straight/axial implants and Group 2 (T, n=33): tilted/angled fixations...
June 3, 2017: Journal of Dentistry
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