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Roderick Willem Treskes, Louise Anna van Winden, Nicole van Keulen, Douwe Ekke Atsma, Enno Tjeerd van der Velde, Elske van den Akker-van Marle, Bart Mertens, Martin Jan Schalij
BACKGROUND: Recent evidence suggests that frequent monitoring using smartphone-compatible wearable technologies might improve clinical effectiveness and patient satisfaction of care. OBJECTIVE: The aim of this study is to investigate the clinical effectiveness and patient satisfaction of a smart technology intervention in patients admitted with a ST elevation myocardial infarction (STEMI) or non-ST acute coronary syndrome (NST-ACS). METHODS: In this single center, open, randomized controlled trial patients who suffered from STEMI or NST-ACS will be randomized 1:1 to an intervention group or control group...
September 22, 2017: JMIR Research Protocols
Josien Engel, Judith M Poldervaart, Ineke van der Wulp, Johannes B Reitsma, Martine C de Bruijne, Jeroen J H Bunge, Maarten J Cramer, Wouter J Tietge, Ruben Uijlings, Cordula Wagner
OBJECTIVE: Cardiac guidelines recommend that the decision to perform coronary angiography (CA) in patients with Non-ST-Elevation Acute Coronary Syndrome (NST-ACS) is based on multiple factors. It is, however, unknown how cardiologists weigh these factors in their decision-making. The aim was to investigate the importance of different clinical characteristics, including information derived from risk scores, in the decision-making of Dutch cardiologists regarding performing CA in patients with suspected NST-ACS...
January 19, 2017: BMJ Open
Josien Engel, Nikki L Damen, Ineke van der Wulp, Martine C de Bruijne, Cordula Wagner
BACKGROUND: In the management of non-ST-elevation acute coronary syndrome (NSTACS) a gap between guideline-recommended care and actual practice has been reported. A systematic overview of the actual extent of this gap, its potential impact on patient-outcomes, and influential factors is lacking. OBJECTIVE: To examine the extent of guideline adherence, to study associations with the occurrence of adverse cardiac events, and to identify factors associated with guideline adherence...
2017: Current Cardiology Reviews
Claudio Cesar Higa, Fedor Anton Novo, Ignacio Nogues, Maria Graciana Ciambrone, Maria Sol Donato, Maria Jimena Gambarte, Natalia Rizzo, Maria Paula Catalano, Eugenio Korolov, Pablo Dino Comignani
BACKGROUND: Microalbuminuria is a known risk factor for cardiovascular morbidity and mortality suggesting that it should be a marker of endothelial dysfunction. Albumin to creatinine ratio (ACR) is an available and rapid test for microalbuminuria determination, with a high correlation with the 24-h urine collection method. There is no prospective study that evaluates the prognostic value of ACR in patients with non ST-segment elevation acute coronary syndromes (NSTE-ACS). The purpose of our study was to detect the long-term prognostic value of ACR in patients with NSTE-ACS...
2016: Cardiology Journal
Erhan Tenekecioglu, Mustafa Yılmaz, Kemal Karaagac, Adem Bekler, Burhan Aslan, Serafettin Demir, Mustafa Kuzeytemiz
AIM OF THE STUDY: Atherosclerosis represents active inflammation in which leukocytes play significant role. Coronary collateral development is a response to myocardial ischaemia. In this study we aimed to investigate the association of the leukocytes with coronary collateral development in patients with non ST-elevated acute coronary syndromes (NST-ACS). MATERIAL AND METHODS: A total of 251 consecutive patients were hospitalized in our hospital with a diagnosis of NST-ACS...
2014: Central-European Journal of Immunology
Adem Bekler, Gokhan Erbag, Hacer Sen, Emine Gazi, Sedat Ozcan
OBJECTIVE: We aimed to study the predictive value of the neutrophil-lymphocyte ratio (NLR) for left ventricular systolic dysfunction (LVSD) in patients with non ST-elevated acute coronary syndrome (NST-ACS). METHODS: A total of 405 patients (mean age 62 years and 75% male) with NST-ACS were included in the study. The study population was divided into tertiles based on admission NLR values. The low, medium and high tertiles defined as NLR≤1.81 (n=135), 1.81<NLR≤3...
January 2015: Pakistan Journal of Medical Sciences Quarterly
Adem Bekler, Erhan Tenekecioğlu, Gökhan Erbağ, Ahmet Temiz, Burak Altun, Ahmet Barutçu, Emine Gazi, Fahri Güneş, Mustafa Yılmaz
OBJECTIVE: Red cell distribution width (RDW) has been reported to be a predictor of cardiac events in coronary artery disease (CAD). Here, we hypothesized that RDW level on admission would be predictive of adverse outcomes in non-ST elevation acute coronary syndrome (NST-ACS). METHODS: In total, 202 patients with NST-ACS (159 males and 43 females) were retrospectively analyzed. The patients were divided into two groups based on the 50th percentile of admission RDW levels...
August 2015: Anatolian Journal of Cardiology
Adem Bekler, Emine Gazi, Mustafa Yılmaz, Ahmet Temiz, Burak Altun, Ahmet Barutçu, Tezcan Peker
OBJECTIVE: The prognostic value of a high platelet-lymphocyte ratio (PLR) has been reported in patients with non-ST elevated myocardial infarction (NSTEMI) and different oncologic disorders. We aimed to evaluate the predictive value of the PLR for left ventricular systolic dysfunction (LVSD) in patients with non-ST elevated acute coronary syndrome (NST-ACS). METHODS: A total of 220 patients with NST-ACS were included in the study. The study population was divided into tertiles based on admission PLR values...
May 2015: Anatolian Journal of Cardiology
Erhan Tenekecioglu, Mustafa Yilmaz, Adem Bekler, Serafettin Demir
BACKGROUND: White blood cells are reported as important not only in plaque vulnerability but also in thrombus formation and thrombus growth in acute coronary syndromes. Eosinophils contain granules that promote thrombus formation and thrombus growth in some heart diseases. In this study we aimed to investigate the relation of eosinophil count with coronary thrombus formation in patients with non ST-elevated acute coronary syndrome (NST-ACS). METHOD: A total of 251 consecutive patients were hospitalized in our hospital with a diagnosis of NST-ACS...
June 2015: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
Adem Bekler, Emine Gazi, Erhan Tenekecioglu, Kemal Karaagac, Burak Altun, Ahmet Temiz, Ahmet Barutçu, Tezcan Peker, Burhan Aslan, Mustafa Yılmaz
BACKGROUND: Red cell distribution width (RDW) and fragmented QRS (fQRS) complexes have also been reported to be pre-dictors of cardiac events and all-cause mortality in coronary artery disease (CAD). We aimed to investigate the association of serum red cell distribution width (RDW) levels and fQRS in patients with non-ST elevated acute coronary syndrome (NST-ACS). MATERIAL AND METHODS: We retrospectively evaluated a total of 251 patients (191 men and 60 women) with NST-ACS...
March 13, 2014: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Mustafa Yilmaz, Erhan Tenekecioglu, Burhan Arslan, Adem Bekler, Ozlem Arican Ozluk, Kemal Karaagac, Fahriye Vatansever Agca, Tezcan Peker, Alkame Akgumus
Leukocytes are reported as crucial not only for plaque activation but also in thrombus formation in acute coronary syndromes (ACSs). Among the markers of inflammation, in coronary artery disease neutrophil-lymphocyte ratio (NLR) has been reported to have the greatest predictive power of poor outcomes. Our aim was to evaluate the association of NLR with coronary thrombus in patients with non-ST-segment elevated ACSs (NST-ACSs). A total of 251 patients were hospitalized with a diagnosis of NST-ACS including non-ST-segment elevated myocardial infarction and unstable angina pectoris...
July 2015: Clinical and Applied Thrombosis/hemostasis
Pedro Carmo, Jorge Ferreira, Carlos Aguiar, António Ferreira, Luís Raposo, Pedro Gonçalves, João Brito, Aniceto Silva
BACKGROUND: Recurrent ischemia is frequent in patients with non-ST-elevation acute coronary syndromes (NST-ACS), and portends a worse prognosis. Continuous ST-segment monitoring (CSTM) reflects the dynamic nature of ischemia and allows the detection of silent episodes. The aim of this study is to investigate whether CSTM adds prognostic information to the risk scores (RS) currently used. METHODS: We studied 234 patients with NST-ACS in whom CSTM was performed in the first 24 hours after admission...
July 2011: Annals of Noninvasive Electrocardiology
Nakarin Sansanayudh, Kitcha Champasri, Chumpol Piamsomboon, Sopon Sanguanwong, Charnarong Narksawasdee, Pannipa Tengtrakulcharoen, Prasart Laotavorn
OBJECTIVE: To assess the efficacy and safety of transradial approach compared with transfemoral approach for coronary angiography and ad hoc angioplasty in Phramongkutklao hospital at the time of initiation of transradial program. MATERIAL AND METHOD: Prospective data collection of consecutive patients who underwent coronary angiography with ad hoc angioplasty during October 2004 to January 2005 was conducted. Baseline demographic data and the details of the procedure were recorded...
November 2010: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Yue-rong Jiang, Hui-jun Yin, Li-zhi Li
OBJECTIVE: To investigate the therapeutic effects of propyl gallate (PrG) in combination with standard medication on patients with non-ST-elevation acute coronary syndrome (NST-ACS), including unstable angina and acute non-ST-elevation myocardial infarction, and its influences on serum inflammatory marker and platelet activation. METHODS: Fifty-five patients with NST-ACS were randomly assigned to two groups. Accessory to the standard Western medicine, the 27 patients in the tested group treated with PrG and the 28 in the control group with salvia composite (SC), all being medicated for 14 days...
September 2008: Chinese Journal of Integrated Traditional and Western Medicine
Antonio Tello-Montoliu, José M Moltó, Nicolás López-Hernández, Ana García-Medina, Vanessa Roldán, Francisco Sogorb, Gregory Y H Lip, Francisco Marín
BACKGROUND: Common carotid intima-media thickness (CIMT) has been related to cardiovascular risk factors, coronary atherosclerosis and a higher risk of myocardial infarction. Evaluation of intracranial arteries by transcranial Doppler explores the presence of vascular dysfunction at this level. We tested the hypothesis that CIMT and Doppler Pulsatility Index (DPI) can be related to the Thrombolysis in Myocardial Infarction (TIMI) risk score for non-ST-elevation acute coronary syndrome (nST-ACS)...
2007: Cerebrovascular Diseases
Javier Jiménez-Candil, Ignacio Cruz González, Francisco Martín, Pedro Pabón, Víctor León, Jesús Hernández, Manuel Sánchez-Flores, José Moríñigo, Claudio Ledesma, Cándido Martín-Luengo
BACKGROUND: Previous studies have shown that prolonged QRS duration increases the risk of death in patients with heart failure and after an ST-segment elevation acute myocardial infarction. Very little data exist about the prognostic implications of QRS duration in the non-ST-segment elevation acute coronary syndrome (NST-ACS): unstable angina and non-ST elevation acute myocardial infarction (non-STEMI). METHODS: This is a prospective and observational study in which we included 502 patients (age 71+/-10 years, 68% males, 29% diabetes) consecutively admitted for NST-ACS...
May 23, 2008: International Journal of Cardiology
Javier Jiménez-Candil, Ignacio Cruz González, José M González Matas, Carmen Albarrán, Pedro Pabón, José Luis Moríñigo, Claudio Ledesma, Francisco Martín, Maximiliano Diego, Cándido Martín-Luengo
BACKGROUND AND PURPOSE: Myocardial ischemia prolongs the QTc interval. Very little data exists about its prognostic implications in the non-ST-elevation acute coronary syndromes (NST-ACS). METHODS: This is and observational and prospective study in which we evaluated the prognostic implications of the QTc obtained at admission (AQTc) in the short- and long-term of the NST-ACS. The median of the follow-up was 17 months. RESULTS: AQTc correlated adequately with the incidence of adverse events in the short- and long-term (P < ...
April 2007: Journal of Electrocardiology
Jean-Paul Bounhoure, Didier Carrié, Jacques Puel
Acute coronary syndromes (ACS) are frequent in the elderly and carry a poor prognosis. Severe coronary artery disease, frequent comorbidity, late diagnosis, and treatments themselves are responsible for high morbidity and mortality rates. Reluctance to treat elderly patients with new mechanical or chemical revascularization techniques is due to the higher risk profile. ACS may or may not be accompanied by ST elevation: STEMI corresponds to acute myocardial infarction before myocardial necrosis, while non STEMI corresponds to unstable angina and subendocardial necrosis...
April 2006: Bulletin de L'Académie Nationale de Médecine
Stefano De Servi, Matteo Mariani, Pietro Vandoni, Antonio Dellavalle, Alessandro Politi, Fabrizio Poletti, Erminio Bonizzoni, Mario Leoncinie
Background In patients with non-ST elevation acute coronary syndrome (NST-ACS) that is treated invasively, glycoprotein (GP) IIb/IIIa inhibitors can be used either as upstream treatment in a coronary care unit or as downstream provisional treatment in selected patients who are undergoing percutaneous coronary intervention (PCI). The relative advantage of either strategy is unknown. The purpose of this study was to assess 30-day outcome of patients enrolled in a prospective NST-ACS registry and treated invasively with either of these two therapeutic strategies...
March 2006: Journal of Cardiovascular Medicine
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