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ocular coherent tomography

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https://www.readbyqxmd.com/read/29787603/association-of-ocular-cardiovascular-morphometric-and-lifestyle-parameters-with-retinal-nerve-fibre-layer-thickness
#1
Julia Lamparter, Irene Schmidtmann, Alexander K Schuster, Angeliki Siouli, Joanna Wasielica-Poslednik, Alireza Mirshahi, René Höhn, Josef Unterrainer, Philipp S Wild, Harald Binder, Karl Lackner, Manfred E Beutel, Thomas Münzel, Norbert Pfeiffer, Esther M Hoffmann
BACKGROUND: Glaucoma is a neurodegenerative disease, leading to thinning of the retinal nerve fibre layer (RNFL). The exact influence of ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFL thickness (RNFLT) is unknown and was analysed in a subgroup of the Gutenberg Health Study (GHS). METHODS: Global peripapillary RNFLT was measured in 3224 eyes of 1973 subjects (49% female) using spectral-domain optical coherence tomography (SD-OCT). The association of age, sex, ocular, cardiovascular, morphometric, lifestyle and cognitive factors on RNFLT was analysed using Pearson correlation coefficient and fitting a linear mixed model...
2018: PloS One
https://www.readbyqxmd.com/read/29787488/effects-of-scleral-lens-tear-clearance-on-corneal-edema-and-post-lens-tear-dynamics-a-pilot-study
#2
Bo Tan, Yixiu Zhou, Tiffany L Yuen, Kristina Lin, Langis Michaud, Meng C Lin
SIGNIFICANCE: The present study with small-diameter scleral lenses (SLs) revealed that post-lens tear thickness (PoLTT) was significantly associated with post-lens tear mixing, but not with central corneal edema, after short-term SL wear. PURPOSE: The aim of this study was to investigate the influence of SL tear clearance (PoLTT) on central corneal thickness and post-lens tear dynamics during 5-hour lens wear. METHODS: Neophytes with no active ocular disease were fitted bilaterally with SLs (hofocon A; 15...
May 21, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29785994/the-efficacy-of-intravitreal-dexamethasone-implant-as-the-first-line-treatment-for-retinal-vein-occlusion-related-macular-edema-in-a-real-life-scenario
#3
Mert Simsek, Mehmet Citirik, Serdar Ozates, Dilara Ozkoyuncu
Purpose: This study evaluated the effect of intravitreal dexamethasone implant (IDI; Ozurdex) injection for treating macular edema in patients with branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO). Methods: This prospective study included 40 eyes of 40 patients with nonischemic BRVO and 31 eyes of 31 patients with nonischemic CRVO who received IDI injection as the first-line treatment for macular edema. The best-corrected visual acuity (BCVA) value before and after the treatment; intraocular pressure; optic coherence tomography findings; and all ocular examination findings, including central foveal thickness (CFT) measurement and fluorescein angiography findings, were evaluated for each patient...
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785984/residency-evaluation-and-adherence-design-study-iii-ophthalmology-residency-training-in-india-then-and-now-improving-with-time
#4
Partha Biswas, Parikshit Madhav Gogate, Quresh Badr Maskati, Sundaram Natarajan, Lalit Verma, Payal K Bansal
Purpose: To gauge the differences in ophthalmology residency training, academic, clinical and surgical, in the last three decades of the 20th century and the first decade of the 21st century. Methods: A survey was conducted by the Academic and Research Committee of the All India Ophthalmological Society, in 2014-2016, using a prevalidated questionnaire, which was circulated to ophthalmologists to gauge the practicality of the teaching protocols of clinical and surgical skills during postgraduate residency program...
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785086/the-utilization-of-an-ocular-wound-chamber-on-corneal-epithelial-wounds
#5
Jennifer S McDaniel, Andrew W Holt, Elaine D Por, Elof Eriksson, Anthony J Johnson, Gina L Griffith
Purpose: Currently available ocular moisture chambers are not adequate to manage the treatment of periocular burns, corneal injuries, and infection. The purpose of these studies was to demonstrate that a flexible, semi-transparent ocular wound chamber device adapted from technology currently used on dermal wounds is safe for use on corneal epithelial injuries. Materials and methods: A depilatory cream (Nair™, 30 seconds) was utilized to remove the excess hair surrounding the left eyes of anesthetized Institute Armand Frappier (IAF) hairless, female guinea pigs (Crl:HA-Hrhr)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29779188/vitreomacular-interface-abnormalities-in-patients-with-diabetic-macular-oedema-and-their-implications-on-the-response-to-anti-vegf-therapy
#6
Michael Mikhail, Stephen Stewart, Felicia Seow, Ruth Hogg, Noemi Lois
PURPOSE: To determine whether the presence of vitreomacular interface abnormalities (VMIA) in patients with diabetic macular oedema (DMO) modifies the response to ranibizumab. METHODS: Medical records and spectral-domain optical coherence tomography (SD-OCT) scans of consecutive patients with centre-involving DMO initiating therapy with ranibizumab between December 2013 and March 2014 at the Belfast Health and Social Care Trust were reviewed. Patients were identified through an electronic database...
May 19, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29777305/the-distribution-of-retinal-nerve-fiber-layer-thickness-and-associations-with-age-refraction-and-axial-length-the-gutenberg-health-study
#7
Esther M Hoffmann, Irene Schmidtmann, Angeliki Siouli, Alexander K Schuster, Manfred E Beutel, Norbert Pfeiffer, Julia Lamparter
PURPOSE: To evaluate the distribution of peripapillary retinal nerve fiber layer thickness as measured by optical coherence tomography and its associations with ocular parameters in a population-based setting. METHODS: In the population-based Gutenberg Health Study, 1974 subjects from the Mainz-Bingen region were scheduled for ophthalmologic examinations, including visual acuity, refraction, tonometry, biometry, and measurements of peripapillary retinal nerve fiber layer thickness (pRNFL) by optical coherence tomography (SD-OCT, Spectralis®, Heidelberg Engineering, Germany)...
May 18, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29776765/effects-of-artificial-tear-treatment-on-corneal-epithelial-thickness-and-corneal-topography-findings-in-dry-eye-patients
#8
B Çakır, E Doğan, E Çelik, T Babashli, T Uçak, G Alagöz
PURPOSE: To investigate the effects of artificial tear treatment on central corneal epithelial thickness, and central, mid-peripheral and peripheral corneal thicknesses in patients with dry eye disease (DED). MATERIAL-METHODS: Patients with DED underwent ocular examinations, including Schirmer-2 test, slit lamp examination for tear break-up time (BUT), corneal topography (CT) for measuring mean central, mid-peripheral and peripheral corneal thickness values and anterior segment optic coherence tomography (AS-OCT) for obtaining central corneal epithelial thickness...
May 15, 2018: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29770905/congenital-grouped-albinotic-spots-of-the-retinal-pigment-epithelium-in-a-patient-with-hemihypertrophy-and-caf%C3%A3-au-lait-spots
#9
Eugenia C White, Jesse D Sengillo, Galaxy Y Cho, Mathieu F Bakhoum, Stephen H Tsang
PURPOSE: To describe the finding of circularly grouped hypomelanotic spots in the central macula of a patient with syndromic characteristics. METHODS: Case report of a patient with albinotic spots grouped within the macula, café au lait spots, and left-sided hemihypertrophy. RESULTS: A 15-year-old boy presented with hypomelanotic spots which were hyperautofluorescent on fundus autofluorescence imaging with no disruption of the retinal laminae or photoreceptor inner and outer segment (IS/OS) junction on spectral domain optical coherence tomography...
May 16, 2018: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29768485/choroidal-thickness-in-normal-indian-subjects-using-swept-source-optical-coherence-tomography
#10
Zeeshan Akhtar, Pukhraj Rishi, Ramasubramanian Srikanth, Ekta Rishi, Muna Bhende, Rajiv Raman
AIM: To determine choroidal thickness in healthy Indian subjects using Swept source optical coherence tomography (SS-OCT). METHODS: In this prospective, observational, cross-sectional study; healthy Indian subjects (n = 230) with no history of ocular and/or systemic disorders were enrolled in the study. Choroidal thickness was measured for 230 eyes using SS-OCT. Subjects were divided into six age groups. Main outcome measures were subfoveal choroidal thickness (SFCT) and macular choroidal thickness (MCT) up to 3 mm at 500-micron interval from the fovea was measured in eight different quadrants...
2018: PloS One
https://www.readbyqxmd.com/read/29768451/intravitreal-ocriplasmin-for-the-treatment-of-vitreomacular-traction-and-macular-hole-a-study-of-efficacy-and-safety-based-on-nice-guidance
#11
Mahiul M K Muqit, Robin Hamilton, Jason Ho, Sally Tucker, Helen Buck
PURPOSE: To evaluate the real world clinical outcomes of intravitreal ocriplasmin in patients with vitreomacular traction (VMT) with and without full thickness macular holes (FTMH) treated according to NICE guidance. METHODS: Retrospective observational case series of 25 patients treated with a single intravitreal ocriplasmin injection between December 2013 and December 2015. Best corrected visual acuity and optical coherence tomography exams were performed to determine visual outcomes and anatomical VMT release and FTMH closure over time...
2018: PloS One
https://www.readbyqxmd.com/read/29767420/ocular-coherence-tomography-measured-changes-over-time-in-anterior-chamber-angle-and-diurnal-intraocular-pressure-after-laser-iridotomy-impact-study
#12
Ivailo Zhekov, Shahina Pardhan, Rupert Ra Bourne
IMPORTANCE: The change in the anatomical dimensions over time and the effect on diurnal intraocular pressure (DIOP) following laser peripheral iridotomy is poorly understood. BACKGROUND: To evaluate change over time in anterior chamber angle anatomy following laser peripheral iridotomy (LPI) in patients with primary angle closure compared to control eyes. Additionally, the effect of LPI on DIOP fluctuation was investigated. DESIGN: Longitudinal, prospective, double-randomized research study...
May 16, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29766541/gold-nanoparticles-in-ophthalmology
#13
REVIEW
Florence Masse, Mathieu Ouellette, Guillaume Lamoureux, Elodie Boisselier
Many research projects are underway to improve the diagnosis and therapy in ophthalmology. Indeed, visual acuity deficits affect 285 million people worldwide and different strategies are being developed to strengthen patient care. One of these strategies is the use of gold nanoparticles (GNP) for their multiple properties and their ability to be used as both diagnosis and therapy tools. This review exhaustively details research developing GNPs for use in ophthalmology. The toxicity of GNPs and their distribution in the eye are described through in vitro and in vivo studies...
May 16, 2018: Medicinal Research Reviews
https://www.readbyqxmd.com/read/29765955/pediatric-multiple-endocrine-neoplasia-type-2b-clinicopathological-correlation-of-perilimbal-mucosal-neuromas-and-treatment-of-secondary-open-angle-glaucoma
#14
Ta Chen Chang, Kingsley C Okafor, Kara M Cavuoto, Sander R Dubovy, Carol L Karp
Ocular findings of multiple endocrine neoplasia type 2B (MEN 2B) include prominent corneal nerves, mucosal neuromas of the conjunctiva, glaucoma, and dry eyes. A 15-year-old girl with MEN 2B presents with advanced secondary open-angle glaucoma and bilateral perilimbal masses. High-resolution optical coherence tomography (HR-OCT) of the perilimbal lesions showed normal epithelial thickness and subepithelial lobular areas of mixed reflectivity, which correlates well with histopathologic findings of benign mucosal neuromas...
April 2018: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/29765199/the-development-of-a-reference-database-with-the-topcon-3d-oct-1-maestro
#15
Michael Chaglasian, Murray Fingeret, Pinakin Gunvant Davey, Wei-Chieh Huang, Danny Leung, Edmund Ng, Charles A Reisman
Importance: The paper presents the range for measurements taken with a new spectral domain optical coherence tomography (OCT) device to establish a reference database for discrimination purposes. Objective: To report the range of thickness values for the new Topcon Maestro 3D OCT device with 2 scan size settings: the 12×9 mm wide field and 6×6 mm scans. Design: Prospective, multicenter cohort study conducted at 7 clinical sites across the USA...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29762268/influence-of-removing-the-large-retinal-vessels-related-effect-on-peripapillary-vessel-density-progression-analysis-in-glaucoma
#16
Gábor Holló
PURPOSE: To investigate the usefulness of removing the large vessel-related information from peripapillary optical coherence tomography (OCT) angiography progression analysis. Peripapillary vessel density (VD) image series which had shown no progression with an earlier software version that did not separate capillary and large vessel-related effects were reevaluated for selective peripapillary capillary VD progression. METHODS: Prospective retinal nerve fiber layer thickness (RNFLT) and peripapillary VD measurements were made using the Angiovue/RTvue-XR OCT on one eye of 9 normal, 20 under treatment ocular hypertensive (OHT) and 24 under treatment open-angle glaucoma patients at 6-month intervals for 2 years (5 visits)...
May 12, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29760969/automated-spectroscopic-retinal-oximetry-with-visible-light-optical-coherence-tomography
#17
Shaohua Pi, Acner Camino, William Cepurna, Xiang Wei, Miao Zhang, David Huang, John Morrison, Yali Jia
Accurate, quantitative assessment of retinal blood oxygen saturation ( sO2 ) may provide a useful early indicator of pathophysiology in several ocular diseases. Here, with visible-light optical coherence tomography (OCT), we demonstrate an automated spectroscopic retinal oximetry algorithm to measure the sO2 within the retinal arteries (A- sO2 ) and veins (V- sO2 ) in rats by automatically detecting the vascular posterior boundary on cross-sectional structural OCT. The algorithm was validated in vitro with flow phantoms and in vivo in rats by comparing the sO2 results, respectively, to those obtained using a blood gas analyzer and pulse oximetry...
May 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29757807/thicknesses-of-central-macular-retinal-nerve-fiber-and-ganglion-cell-inner-plexiform-layers-in-patients-with-hypertension
#18
Soo Hyun Lee, Woo Hyuk Lee, Hyung Bin Lim, Young Joon Jo, Jung Yeul Kim
PURPOSE: To compare retinal thickness between patients with chronic hypertension without retinopathy, hypertensive retinopathy, Keith-Wagener-Barker Grade IV status, and normal controls using spectral domain optical coherence tomography. METHODS: In this retrospective study, we analyzed patients who visited our retinal clinic from January 2013 to February 2016. Of those included, 58 eyes of 58 patients were in the healthy control group (Group A), 37 eyes of 37 patients were in the chronic hypertension without retinopathy group (disease duration of at least 10 years; Group B), and 31 eyes of 31 patients with relieved hypertensive retinopathy (Grade IV hypertensive retinopathy a year or more ago but no longer had hypertensive retinopathy at the time of the study; Group C)...
May 11, 2018: Retina
https://www.readbyqxmd.com/read/29757019/optical-coherence-tomography-angiography-in-glaucoma-care
#19
Sunee Chansangpetch, Shan C Lin
Rapid improvements in optical coherence tomography (OCT) technology have allowed for enhancement of both image resolution and scanning speed, and the development of vascular assessment modality. Optical coherence tomography angiography (OCTA) is the non-invasive in vivo imaging of the vasculature located within the retina and optic nerve head area. The principle of OCTA is to use the variations in OCT signals caused by moving particles as the contrast mechanism for imaging of flow. Several algorithms which aim to maximize the contrast signal and minimize the noise have been developed including the phase-based techniques, intensity-based techniques (e...
May 14, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29755817/comparison-of-electrocoagulation-and-conventional-medical-drops-for-treatment-of-conjunctivochalasis-short-term-results
#20
Mehtap Çağlayan, Pınar Kösekahya, Canan Gürdal, Özge Saraç
Objectives: To compare the effectiveness of electrocoagulation and conventional medical drops for treatment of conjunctivochalasis using anterior segment-optical coherence tomography (AS-OCT). Materials and Methods: Forty eyes of 20 patients with bilateral conjunctivochalasis were included in this prospective study. Twenty eyes of 10 patients were assigned to Group 1 and underwent electrocoagulation. The other 20 eyes of 10 patients were assigned to Group 2 and received conventional medical treatment consisting of non-steroidal antiinflammatory drop (topical 0...
April 2018: Turkish Journal of Ophthalmology
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