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https://www.readbyqxmd.com/read/29916586/-personalized-medicine-and-medical-malpractice
#1
Santo Davide Ferrara, Guido Viel
OBJECTIVES: The manuscript deals with personalized medicine and medical liability in Europe and Italy, addressing the importance of synergistic collaboration between clinical and medico-legal professionals in order to appropriately investigate medical errors and prevent any future adverse event. METHODS: Following a rapid epidemiological overview of mala praxis in Europe, the manuscript presents and discusses the International Guidelines developed and adopted by the International Academy of Legal Medicine (IALM), which guide the work of the medical experts under both criminal and/or civil law...
November 2017: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29910658/clinical-practice-guidelines-in-breast-cancer
#2
REVIEW
N Kumar Tyagi, S Dhesy-Thind
Background: A number of clinical practice guidelines (cpgs) concerning breast cancer (bca) screening and management are available. Here, we review the strengths and weaknesses of cpgs from various professional organizations and consensus groups with respect to their methodologic quality, recommendations, and implementability. Methods: Guidelines from four groups were reviewed with respect to two clinical scenarios: adjuvant ovarian function suppression (ofs) in premenopausal women with early-stage estrogen receptor-positive bca, and use of sentinel lymph node biopsy (slnb) after neoadjuvant chemotherapy (nac) for locally advanced bca...
June 2018: Current Oncology
https://www.readbyqxmd.com/read/29901487/a-core-set-of-outcome-measures-for-adults-with-neurologic-conditions-undergoing-rehabilitation-a-clinical-practice-guideline
#3
Jennifer L Moore, Kirsten Potter, Kathleen Blankshain, Sandra L Kaplan, Linda C OʼDwyer, Jane E Sullivan
BACKGROUND: Use of outcome measures (OMs) in adult neurologic physical therapy is essential for monitoring changes in a patient's status over time, quantifying observations and patient-reported function, enhancing communication, and increasing the efficiency of patient care. OMs also provide a mechanism to compare patient and organizational outcomes, examine intervention effectiveness, and generate new knowledge. This clinical practice guideline (CPG) examined the literature related to OMs of balance, gait, transfers, and patient-stated goals to identify a core set of OMs for use across adults with neurologic conditions and practice settings...
June 12, 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29901241/evaluation-of-all-african-clinical-practice-guidelines-for-hypertension-quality-and-opportunities-for-improvement
#4
Patrick Mbah Okwen, Irene Maweu, Karen Grimmer, Janine Margarita Dizon
RATIONALE, AIMS, AND OBJECTIVES: Good-quality clinical practice guidelines (CPGs) provide recommendations based on current best-evidence summaries. Hypertension is a prevalent noncommunicable disease in Africa, with disastrous sequelae (stroke, heart, and kidney disease). Its effective management relies on good quality, current, locally relevant evidence. This paper reports on an all African review of the guidance documents currently informing hypertension management. METHODS: Attempts were made to contact 62 African countries for formal guidance documents used nationally to inform diagnosis and management of hypertension...
June 14, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29898974/practice-guideline-update-summary-efficacy-and-tolerability-of-the-new-antiepileptic-drugs-ii-treatment-resistant-epilepsy-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american
#5
Andres M Kanner, Eric Ashman, David Gloss, Cynthia Harden, Blaise Bourgeois, Jocelyn F Bautista, Bassel Abou-Khalil, Evren Burakgazi-Dalkilic, Esmeralda Llanas Park, John Stern, Deborah Hirtz, Mark Nespeca, Barry Gidal, Edward Faught, Jacqueline French
OBJECTIVE: To update the 2004 American Academy of Neurology guideline for managing treatment-resistant (TR) epilepsy with second- and third-generation antiepileptic drugs (AEDs). METHODS: 2004 criteria were used to systemically review literature (January 2003 to November 2015), classify pertinent studies according to the therapeutic rating scheme, and link recommendations to evidence strength. RESULTS: Forty-two articles were included. RECOMMENDATIONS: The following are established as effective to reduce seizure frequency (Level A): immediate-release pregabalin and perampanel for TR adult focal epilepsy (TRAFE); vigabatrin for TRAFE (not first-line treatment); rufinamide for Lennox-Gastaut syndrome (LGS) (add-on therapy)...
June 13, 2018: Neurology
https://www.readbyqxmd.com/read/29898971/practice-guideline-update-summary-efficacy-and-tolerability-of-the-new-antiepileptic-drugs-i-treatment-of-new-onset-epilepsy-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american
#6
Andres M Kanner, Eric Ashman, David Gloss, Cynthia Harden, Blaise Bourgeois, Jocelyn F Bautista, Bassel Abou-Khalil, Evren Burakgazi-Dalkilic, Esmeralda Llanas Park, John Stern, Deborah Hirtz, Mark Nespeca, Barry Gidal, Edward Faught, Jacqueline French
OBJECTIVE: To update the 2004 American Academy of Neurology (AAN) guideline for treating new-onset focal or generalized epilepsy with second- and third-generation antiepileptic drugs (AEDs). METHODS: The 2004 AAN criteria were used to systematically review literature (January 2003-November 2015), classify pertinent studies according to the therapeutic rating scheme, and link recommendations to evidence strength. RESULTS: Several second-generation AEDs are effective for new-onset focal epilepsy...
June 13, 2018: Neurology
https://www.readbyqxmd.com/read/29891180/clinical-practice-guidelines-for-the-treatment-of-primary-liver-cancer-with-integrative-traditional-chinese-and-western-medicine
#7
Chang-Quan Ling, Jia Fan, Hong-Sheng Lin, Feng Shen, Zhen-Ye Xu, Li-Zhu Lin, Shu-Kui Qin, Wei-Ping Zhou, Xiao-Feng Zhai, Bai Li, Qing-Hui Zhou
Traditional Chinese medicine (TCM) is an important part of the treatment of primary liver cancer (PLC) in China; however, the current instructions for the integrative use of traditional Chinese and Western medicine for PLC are mostly based on expert opinion. There is no evidence-based guideline for clinical practice in this field. Therefore, the Shanghai Association of Chinese Integrative Medicine has established a multidisciplinary working group to develop this guideline, which focuses on the most important questions about the use of TCM during PLC treatment...
May 17, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29889263/update-version-of-the-japanese-guidelines-for-gastric-cancer-screening
#8
Chisato Hamashima
Background: Although the incidence and mortality of gastric cancer have gradually decreased, its burden remains in East Asian countries. Gastric cancer screening has been performed in Japan since 1983, and the introduction of new screening techniques has been eagerly anticipated. Objective: To promote evidence-based screening, the Japanese guidelines for gastric cancer screening have been revised based on the new studies. Methods: The guidelines for gastric cancer screening have been developed according to a previously established method...
June 8, 2018: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29888092/emergency-department-clinician-perspectives-on-the-data-availability-to-implement-clinical-decision-support-tools-for-five-clinical-practice-guidelines
#9
Brian J Douthit, Rachel L Richesson
Clinical practice guidelines (CPGs) often serve as the knowledge base for clinical decision support (CDS). While CPGs are rigorously created by medical professional societies, the concepts in each guideline may not be sufficient for translation into CDS applications. In addition, clinicians' perceptions of these concepts may differ greatly, affecting the implementation and impact of CDS within an organization. Five guidelines developed by the American College of Emergency Physicians were systematically explored, generating fifty-one unique clinical concepts...
2018: AMIA Summits on Translational Science Proceedings
https://www.readbyqxmd.com/read/29876877/should-low-and-middle-income-countries-adopt-clinical-guidelines-developed-in-rich-countries
#10
EDITORIAL
Alan Haycox
No abstract text is available yet for this article.
June 7, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29876799/practical-guidance-for-the-implementation-of-stress-echocardiography
#11
Kengo Suzuki, Yutaka Hirano, Hirotsugu Yamada, Mitsushige Murata, Masao Daimon, Masaaki Takeuchi, Yoshihiro Seo, Chisato Izumi, Makoto Akaishi
Exercise stress testing has been widely undertaken for the diagnosis of heart diseases. The accurate assessment of clinical conditions can be conducted by comparing the findings obtained from the results of stress echocardiography with the changes in the blood/heart rate and electrocardiograms. Numerous overseas studies have reported the utility of stress echocardiography in diagnosing myocardial ischemia; in Japan, the use of this modality for this purpose was included in the national health insurance reimbursable list in 2012...
June 6, 2018: Journal of Echocardiography
https://www.readbyqxmd.com/read/29873949/evaluation-of-the-impact-of-a-multimodel-intervention-on-prescribing-patterns-of-sedative-hypnotics-in-a-behavioral-health-system
#12
Korana Avdagic, Michelle Geier, Zlatan Coralic, Patrick Finley
Objective: To describe the effect of a multimodal intervention targeting chronic benzodiazepine and sedative-hypnotic prescriptions in a large behavioral health system. Methods: This retrospective study analyzed chronic sedative-hypnotic prescription rates in patients seeking mental health services in a large behavioral health system. The multimodal intervention consisted of provider education, coordination of care with all providers involved in patient care, and guideline development and implementation for safe prescribing of sedative-hypnotics...
May 31, 2018: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29859534/burden-of-cardiovascular-risk-factors-and-disease-among-patients-with-type-1-diabetes-results-of-the-australian-national-diabetes-audit-anda
#13
Anthony Pease, Arul Earnest, Sanjeeva Ranasinha, Natalie Nanayakkara, Danny Liew, Natalie Wischer, Sofianos Andrikopoulos, Sophia Zoungas
BACKGROUND: Cardiovascular risk stratification is complex in type 1 diabetes. We hypothesised that traditional and diabetes-specific cardiovascular risk factors were prevalent and strongly associated with cardiovascular disease (CVD) among adults with type 1 diabetes attending Australian diabetes centres. METHODS: De-identified, prospectively collected data from patients with type 1 diabetes aged ≥ 18 years in the 2015 Australian National Diabetes Audit were analysed...
June 2, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29846947/colorectal-cancer-screening-for-average-risk-adults-2018-guideline-update-from-the-american-cancer-society
#14
Andrew M D Wolf, Elizabeth T H Fontham, Timothy R Church, Christopher R Flowers, Carmen E Guerra, Samuel J LaMonte, Ruth Etzioni, Matthew T McKenna, Kevin C Oeffinger, Ya-Chen Tina Shih, Louise C Walter, Kimberly S Andrews, Otis W Brawley, Durado Brooks, Stacey A Fedewa, Deana Manassaram-Baptiste, Rebecca L Siegel, Richard C Wender, Robert A Smith
In the United States, colorectal cancer (CRC) is the fourth most common cancer diagnosed among adults and the second leading cause of death from cancer. For this guideline update, the American Cancer Society (ACS) used an existing systematic evidence review of the CRC screening literature and microsimulation modeling analyses, including a new evaluation of the age to begin screening by race and sex and additional modeling that incorporates changes in US CRC incidence. Screening with any one of multiple options is associated with a significant reduction in CRC incidence through the detection and removal of adenomatous polyps and other precancerous lesions and with a reduction in mortality through incidence reduction and early detection of CRC...
May 30, 2018: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29843743/the-grade-evidence-to-decision-etd-framework-for-health-system-and-public-health-decisions
#15
REVIEW
Jenny Moberg, Andrew D Oxman, Sarah Rosenbaum, Holger J Schünemann, Gordon Guyatt, Signe Flottorp, Claire Glenton, Simon Lewin, Angela Morelli, Gabriel Rada, Pablo Alonso-Coello
OBJECTIVE: To describe a framework for people making and using evidence-informed health system and public health recommendations and decisions. BACKGROUND: We developed the GRADE Evidence to Decision (EtD) framework for health system and public health decisions as part of the DECIDE project, in which we simultaneously developed frameworks for these and other types of healthcare decisions, including clinical recommendations, coverage decisions and decisions about diagnostic tests...
May 29, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29843737/the-advantages-and-limitations-of-guideline-adaptation-frameworks
#16
Zhicheng Wang, Susan L Norris, Lisa Bero
BACKGROUND: The implementation of evidence-based guidelines can improve clinical and public health outcomes by helping health professionals practice in the most effective manner, as well as assisting policy-makers in designing optimal programs. Adaptation of a guideline to suit the context in which it is intended to be applied can be a key step in the implementation process. Without taking the local context into account, certain interventions recommended in evidence-based guidelines may be infeasible under local conditions...
May 29, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29800249/identification-and-description-of-reliable-evidence-for-2016-american-academy-of-ophthalmology-preferred-practice-pattern-guidelines-for-cataract-in-the-adult-eye
#17
Asieh Golozar, Yujiang Chen, Kristina Lindsley, Benjamin Rouse, David C Musch, Flora Lum, Barbara S Hawkins, Tianjing Li
Importance: Trustworthy clinical practice guidelines require reliable systematic reviews of the evidence to support recommendations. Since 2016, the American Academy of Ophthalmology (AAO) has partnered with Cochrane Eyes and Vision US Satellite to update their guidelines, the Preferred Practice Patterns (PPP). Objective: To describe experiences and findings related to identifying reliable systematic reviews that support topics likely to be addressed in the 2016 update of the 2011 AAO PPP guidelines on cataract in the adult eye...
May 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29799155/listeria-then-and-now-a-call-to-reevaluate-patient-teaching-based-on-analysis-of-us-federal-databases-1998-2016
#18
Katya Simon, Valentina Simon, Rachel Rosenzweig, Rebeca Barroso, Mickey Gillmor-Kahn
INTRODUCTION: Listeria monocytogenes is a foodborne pathogen capable of crossing the placental-fetal barrier; infection with the bacterium causes listeriosis. An exposed fetus may suffer blindness, neurological damage including meningitis, or even death. The adverse consequences of listeriosis place the infection on the federally reportable disease list. Primary prevention relies on women avoiding 6 categories of foods most likely to be contaminated with L monocytogenes, as indicated in guidelines developed by the Centers for Disease Control and Prevention (CDC), adapted by the American College of Obstetricians and Gynecologists (ACOG) in 2014, and reaffirmed without changes by ACOG in 2016...
May 24, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29794431/the-problem-relevance-quality-and-homogeneity-of-trial-designs-outcomes-and-reporting
#19
Gerd Göstemeyer, Colin Levey
Clinical trials are the cornerstone of evidence-based medicine. By directly comparing different interventions they produce evidence on their relative efficacy and effectiveness This, in turn, can inform secondary research and guideline development to facilitate evidence-based clinical decision making. However, the quality of evidence stemming from clinical trials is frequently poor. Here, the pathway of evidence from basic research to the generation of implementable clinical guidelines will be described. Relevant factors related to trial design and reporting, such as the choice of trial comparators, outcomes and outcome measures, will be described and their influence on evidence synthesis will be discussed...
May 24, 2018: Monographs in Oral Science
https://www.readbyqxmd.com/read/29791429/-clinical-practice-guideline-for-the-evaluation-and-management-of-upper-gastrointestinal-bleeding-for-the-peruvian-social-security-essalud
#20
Jorge Vásquez-Quiroga, Alvaro Taype-Rondan, Jessica Hanae Zafra-Tanaka, Ericson Arcana-López, Luis Cervera-Caballero, Javier Contreras-Turin, Katherine Guzmán-Cáceres, Juan Llatas-Perez, Luis Marin-Calderón, Alejandro Piscoya, Daniel Vargas-Blácido, Nelly Vásquez-Valverde, Raúl Timaná-Ruiz
OBJECTIVE: To provide evidence-based clinical recommendations for the evaluation and management of patients with upper gastrointestinal bleeding (UGB) in the Peruvian Social Security (EsSalud). MATERIALS AND METHODS: A local guideline development group (local GDG) was established, including specialists in gastroenterology and methodologists. The local GDG formulated 11 clinical questions to be answered by this clinical practice guide (CPG). We searched and selected CPG of UGB published from 2012, which answered the posed questions and obtained a score higher than 60% in domains 1 and 3 of the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) tool...
January 2018: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
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