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https://www.readbyqxmd.com/read/28448204/future-research-opportunities-in-peri-prosthetic-joint-infection-prevention
#1
Elie Berbari, John Segreti, Javad Parvizi, Sandra I Berríos-Torres
Peri-prosthetic joint infection (PJI) is a serious complication of prosthetic joint arthroplasty. A better understanding and reversal of modifiable risk factors may lead to a reduction in the incidence of incisional (superficial and deep) and organ/space (e.g., PJI) surgical site infections (SSI). Recently, the Centers for Disease Control and Prevention (CDC) and the Healthcare Infection Control Practices Advisory Committee (HICPAC) published the Guideline for Prevention of Surgical Site Infection. This targeted update applies evidence-based methodology in drafting recommendations for potential strategies to reduce the risk of SSI both across surgical procedures and specifically in prosthetic joint arthroplasty...
April 27, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28438841/practice-guideline-summary-sudden-unexpected-death-in-epilepsy-incidence-rates-and-risk-factors-report-of-the-guideline-development-dissemination-and-implementation-subcommittee-of-the-american-academy-of-neurology-and-the-american-epilepsy-society
#2
Cynthia Harden, Torbjörn Tomson, David Gloss, Jeffrey Buchhalter, J Helen Cross, Elizabeth Donner, Jacqueline A French, Anthony Gil-Nagel, Dale C Hesdorffer, W Henry Smithson, Mark C Spitz, Thaddeus S Walczak, Josemir W Sander, Philippe Ryvlin
OBJECTIVE: To determine the incidence rates of sudden unexpected death in epilepsy (SUDEP) in different epilepsy populations and address the question of whether risk factors for SUDEP have been identified. METHODS: Systematic review of evidence; modified Grading Recommendations Assessment, Development, and Evaluation process for developing conclusions; recommendations developed by consensus. RESULTS: Findings for incidence rates based on 12 Class I studies include the following: SUDEP risk in children with epilepsy (aged 0-17 years) is 0...
April 25, 2017: Neurology
https://www.readbyqxmd.com/read/28425182/serum-ferritin-thresholds-for-the-diagnosis-of-iron-deficiency-in-pregnancy-a-systematic-review
#3
REVIEW
J Daru, J Allotey, J P Peña-Rosas, K S Khan
The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing the global prevalence of anaemia in women of reproductive age is a 2025 global nutrition target. Bone marrow aspiration is the gold standard test for iron deficiency but requires an invasive procedure; therefore, serum ferritin is the most clinically useful test...
April 20, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28412464/grade-equity-guidelines-1-health-equity-in-guideline-development-introduction-and-rationale
#4
Vivian A Welch, Elie A Akl, Gord Guyatt, Kevin Pottie, Javier Eslava-Schmalbach, Mohammed T Ansari, Hans de Beer, Matthias Briel, Tony Dans, Inday Dans, Monica Hultcrantz, Janet Jull, Srinivasa Vittal Katikireddi, Joerg Meerpohl, Rachael Morton, Annhild Mosdol, Jennifer Petkovic, Holger Schünemann, Ravi Sharaf, Jasvinder Singh, Roger Stanev, Thomy Tonia, Mario Tristan, Sigurd Vitols, Joseph Watine, Peter Tugwell
OBJECTIVES: This paper introduces the rationale and methods for explicitly considering health equity in the GRADE methodology for development of clinical, public health and health system guidelines. STUDY DESIGN AND SETTING: guidance for guideline development STUDY DESIGN AND SETTING: We searched for guideline methodology papers, conceptual papers about health equity and examples of guidelines which considered health equity explicitly. We held three meetings with GRADE working group members, and invited comments from the GRADE working group listserve RESULTS: We developed three papers on incorporating equity considerations into the overall approach to guideline development, rating certainty and assembling the evidence base and evidence to decision/recommendation...
April 12, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28412463/frameworks-for-adaptation-of-health-guidelines-a-methodological-survey
#5
REVIEW
Andrea Darzi, Elias A Abou-Jaoude, Arnav Agarwal, Chantal Lakis, Wojtek Wiercioch, Nancy Santesso, Hneine Brax, Fadi El-Jardali, Holger J Schünemann, Elie A Akl
BACKGROUND: Our objective was to identify and describe published frameworks for adaptation of clinical, public health and health services guidelines. METHODS: We included reports describing methods of adaptation of guidelines in sufficient detail to allow its reproducibility. We searched Medline, and EMBASE databases. We also searched personal files, as well manuals and handbooks of organizations and professional societies that proposed methods of adaptation and adoption of guidelines...
April 12, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28411519/-breaking-good-news-neurologists-experiences-of-discussing-sudep-with-patients-in-scotland
#6
Tom Nisbet, Sue Turbull, Sharon Mulhern, Saif Razvi
Since the findings of a Fatal Accident Inquiry (FAI) in 2010, clinicians working in Scotland have been advised to discuss the risk of Sudden Unexpected Death in Epilepsy (SUDEP) with patients immediately or soon after a diagnosis of epilepsy is made. A thematic analysis was used to describe the experiences discussing SUDEP of 10 clinicians (six Consultant Neurologists and four Neurology Registrars) working in Scotland. Contrary to previous research, clinicians appear to be routinely discussing SUDEP in a standardized fashion with newly diagnosed patients and the FAI appears to have instigated this change in practice...
April 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28411155/trial-timing-and-pattern-information-analyses-of-fmri-data
#7
Dagmar Zeithamova, Maria-Alejandra de Araujo Sanchez, Anisha Adke
Pattern-information approaches to fMRI data analysis are becoming increasingly popular but few studies to date have investigated experimental design optimization for these analyses. Here, we tested several designs that varied in the number of trials and trial timing within fixed duration scans while participants encoded images of animals and tools. Trial timing conditions with fixed onset-to-onset timing ranged from slow 12-second trials with two repetitions of each item to quick 6-second trials with four repetitions per item...
April 11, 2017: NeuroImage
https://www.readbyqxmd.com/read/28407472/introduction-to-the-centers-for-disease-control-and-prevention-and-healthcare-infection-control-practices-advisory-committee-guideline-for-prevention-of-surgical-site-infection-prosthetic-joint-arthroplasty-section
#8
John Segreti, Javad Parvizi, Elie Berbari, Philip Ricks, Sandra I Berríos-Torres
Peri-prosthetic joint infection (PJI) is a severe complication of total joint arthroplasty that appears to be increasing as more of these procedures are performed. Numerous risk factors for incisional (superficial and deep) and organ/space (e.g., PJI) surgical site infections (SSIs) have been identified. A better understanding and reversal of modifiable risk factors may lead to a reduction in the incidence of incisional SSI and PJI. The Centers for Disease Control and Prevention (CDC) and the Healthcare Infection Control Practices Advisory Committee (HICPAC) recently updated the national Guideline for Prevention of Surgical Site Infection...
April 13, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28399329/adapting-a-large-database-of-point-of-care-summarized-guidelines-a-process-description
#9
Nicolas Delvaux, Stijn Van de Velde, Bert Aertgeerts, Martine Goossens, Benjamin Fauquert, Ilka Kunnamo, Paul Van Royen
RATIONALE, AIMS AND OBJECTIVES: Questions posed at the point of care (POC) can be answered using POC summarized guidelines. To implement a national POC information resource, we subscribed to a large database of POC summarized guidelines to complement locally available guidelines. Our challenge was in developing a sustainable strategy for adapting almost 1000 summarized guidelines. The aim of this paper was to describe our process for adapting a database of POC summarized guidelines. METHODS: An adaptation process based on the ADAPTE framework was tailored to be used by a heterogeneous group of participants...
February 2017: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/28389397/grade-equity-guidelines-3-health-equity-considerations-in-rating-the-certainty-of-synthesized-evidence
#10
Vivian A Welch, Elie A Akl, Kevin Pottie, Mohammed T Ansari, Matthias Briel, Robin Christensen, Antonio Dans, Leonila Dans, Javier H Eslava-Schmalbach, Gordon Guyatt, Monica Hultcrantz, Janet Jull, Srinivasa Vittal Katikireddi, Eddy Lang, Elizabeth Matovinovic, Joerg J Meerpohl, Rachael Morton, Annhild Mosdøl, M Hassan Murad, Jennifer Petkovic, Holger Schünemann, Ravi Sharaf, Beverley Shea, Jasvinder A Singh, Ivan Solà, Roger Stanev, Airton Tetelbom Stein, Lehana Thabane, Thomy Tonia, Mario Tristan, Sigurd Vitols, Joseph Watine, Peter Tugwell
OBJECTIVE: The aim of this paper is to describe a conceptual framework for how to consider health equity in the GRADE (Grading Recommendations Assessment and Development Evidence) guideline development process. STUDY DESIGN AND SETTING: Consensus-based guidance developed by the GRADE working group members and other methodologists. RESULTS: We developed consensus-based guidance to help address health equity when rating the certainty of synthesized evidence (i...
April 4, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28381378/severe-acute-pancreatitis-pathogenesis-diagnosis-and-surgical-management
#11
Mark Portelli, Christopher David Jones
BACKGROUND: Severe acute pancreatitis is a subtype of acute pancreatitis, associated with multiple organ failure and systemic inflammatory response syndrome. In this qualitative review we looked at the principles of pathogenesis, classification and surgical management of severe acute pancreatitis. We also looked at the current shift in paradigm in the management of severe acute pancreatitis since the guideline developed by the British Society of Gastroenterology. DATA SOURCES: Studies published between 1st January 1991 and 31st December 2015 were identified with PubMed, MEDLINE, EMBASE and Google Scholar online search engines using the following Medical Subject Headings: "acute pancreatitis, necrosis, mortality, pathogenesis, incidence" and the terms "open necrosectomy and minimally invasive necrosectomy"...
April 2017: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/28372958/toward-a-framework-for-benefit-risk-assessment-in-diagnostic-imaging-identifying-scenario-specific-criteria
#12
Maria Agapova, Brian W Bresnahan, Ken F Linnau, Louis P Garrison, Mitchell Higashi, Larry Kessler, Beth Devine
RATIONALE AND OBJECTIVES: Diagnostic imaging has many effects and there is no common definition of value in diagnostic radiology. As benefit-risk trade-offs are rarely made explicit, it is not clear which framework is used in clinical guideline development. We describe initial steps toward the creation of a benefit-risk framework for diagnostic radiology. MATERIALS AND METHODS: We performed a literature search and an online survey of physicians to identify and collect benefit-risk criteria (BRC) relevant to diagnostic imaging tests...
March 31, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28369374/a-qualitative-study-of-the-determinants-of-hiv-guidelines-implementation-in-two-south-eastern-districts-of-tanzania
#13
Mary N Mwangome, Eveline Geubbels, Alison Wringe, Jim Todd, Paul Klatser, Marjolein Dieleman
Current HIV policies in Tanzania have adopted the three long-term impact results of zero new infections, zero HIV deaths and zero stigma and discrimination. Strategies to reach these results include scaling-up HIV Testing and Counselling (HTC); Preventing Mother-To-Child Transmission (PMTCT); and strengthening Care and Treatment Clinic (CTC) services. Previous studies showed that HIV policy and guideline recommendations were not always implemented in rural South Tanzania. This study aims to identify the determinants of HIV guideline implementation...
March 22, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28363670/using-the-analytic-hierarchy-process-for-prioritizing-imaging-tests-in-diagnosis-of-suspected-appendicitis
#14
Maria Agapova, Brian W Bresnahan, Ken F Linnau, Louis P Garrison, Mitchell Higashi, Larry Kessler, Beth Devine
RATIONALE AND OBJECTIVES: In clinical guideline or criteria development processes, such as those used in developing American College of Radiology Appropriateness Criteria (ACR AC), experts subjectively evaluate benefits and risks associated with imaging tests and make complex decisions about imaging recommendations. The analytic hierarchy process (AHP) decomposes complex decisions into structured smaller decisions, incorporates quantitative evidence and qualitative expert opinion, and promotes structured consensus building...
March 28, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28360378/a-systematic-review-and-appraisal-of-the-quality-of-practice-guidelines-for-the-management-of-neisseria-gonorrhoeae-infections
#15
Catherine Dickson, Trevor Arnason, Dara Spatz Friedman, Gila Metz, Jeremy M Grimshaw
BACKGROUND: Clinical guidelines help ensure consistent care informed by current evidence. As shifts in antimicrobial resistance continue to influence first-line treatment, up-to-date guidelines are important for preventing treatment failure. A guideline's development process will influence its recommendations and users' trust. OBJECTIVE: To assess the quality of current gonorrhoea guidelines' development processes. DATA SOURCES: Multiple databases...
March 30, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28353127/testicular-tissue-cryopreservation-and-ethical-considerations-a-scoping-review
#16
Angel Petropanagos
Testicular tissue cryopreservation (TTCP) aims to preserve the future option of genetic reproduction for prepubescent cancer patients who are at risk of infertility as a result of their cancer therapies. This technology is experimental and currently only offered in the research context. As TTCP moves towards becoming more widely available, it is imperative that healthcare providers recognize the complex ethical issues surrounding this technology. This scoping review study identifies and assesses the range and depth of ethical concerns related to this testicular tissue cryopreservation technology...
March 28, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28349646/quality-improvement-of-community-pharmacy-services-a-prioritisation-exercise
#17
Rumana S Newlands, Ailsa Power, Linda Young, Margaret Watson
OBJECTIVES: Effective strategies are needed to translate knowledge (evidence) into practice to improve the quality of community pharmacy services. We report the first step of a novel knowledge translation process which involved the systematic identification and prioritisation of community pharmacy services in Scotland which were perceived to require improvement and/or guideline development. METHODS: This process involved three stages and a stakeholder group comprising community pharmacists, policy makers, lay and pharmacy organisation representatives...
March 27, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28349577/critical-appraisal-of-clinical-practice-guidelines-for-adult-cancer-patients-with-febrile-neutropenia
#18
Ziad G Nasr, Safae Abu Yousef, Farah Jibril, Kyle J Wilby
OBJECTIVES: To critically appraise published international clinical practice guidelines (CPGs) for management of febrile neutropenia in adult patients with cancer and to determine opportunities for improved development and reporting. METHODS: A literature search identified CPGs for adult cancer patients with febrile neutropenia. Four independent assessors evaluated each included CPG according to the Appraisal of Guidelines for Research and Evaluation II instrument...
March 27, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28347696/workplace-mental-health-an-international-review-of-guidelines
#19
REVIEW
Kate Memish, Angela Martin, Larissa Bartlett, Sarah Dawkins, Kristy Sanderson
The aim of this systematic review was to determine the quality and comprehensiveness of guidelines developed for employers to detect, prevent, and manage mental health problems in the workplace. An integrated approach that combined expertise from medicine, psychology, public health, management, and occupational health and safety was identified as a best practice framework to assess guideline comprehensiveness. An iterative search strategy of the grey literature was used plus consultation with experts in psychology, public health, and mental health promotion...
March 24, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28341034/outcome-assessment-in-total-knee-arthroplasty-a-systematic-review-and-critical-appraisal
#20
REVIEW
Toni Lange, Elisabeth Rataj, Christian Kopkow, Jörg Lützner, Klaus-Peter Günther, Jochen Schmitt
BACKGROUND: The Outcome Measures in Rheumatology (OMERACT) initiative developed a core outcome set (COS) of domains to assess effectiveness of interventions for knee osteoarthritis. These domains (pain, physical function, patient global assessment, imaging at 1 year) should be assessed in every trial to make research evidence meaningful and comparable. We systematically evaluated and critically appraised the use of measurement instruments and outcome domains in prospective studies evaluating patients with knee osteoarthritis undergoing total knee arthroplasty (TKA) and assessed their accordance with the OMERACT COS...
February 2017: Journal of Arthroplasty
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