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https://www.readbyqxmd.com/read/28731265/application-of-dead-end-knockout-zebrafish-as-recipients-of-germ-cell-transplantation
#1
Qian Li, Wataru Fujii, Kunihiko Naito, Goro Yoshizaki
Germ cell transplantation is a promising technology for the propagation of endangered or valuable fishes. In this technique, sterile male and female recipient fish are injected with donor germ cells so they can produce viable gametes derived from the donor cells. The dead end (dnd) gene is involved in the migration of primordial germ cells; therefore, dnd-knockout zebrafish are expected to be germ-cell-free, making them suitable recipients for germ cell transplantation. dnd mutants were produced by microinjecting 2 nl of 10 ng/μl cRNAs encoding zinc finger nucleases against dnd into the blastodisc of zebrafish embryos before the cell cleavage stage...
July 21, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28729121/multiple-myeloma-genomics-a-systematic-review
#2
REVIEW
Casey J Weaver, Joseph D Tariman
OBJECTIVES: This integrative review describes the genomic variants that have been found to be associated with poor prognosis in patients diagnosed with multiple myeloma (MM). Second, it identifies MM genetic and genomic changes using next-generation sequencing, specifically whole-genome sequencing or exome sequencing. DATA SOURCE: A search for peer-reviewed articles through PubMed, EBSCOhost, and DePaul WorldCat Libraries Worldwide yielded 33 articles that were included in the final analysis...
July 18, 2017: Seminars in Oncology Nursing
https://www.readbyqxmd.com/read/28727994/retrospective-evaluation-of-the-procedural-sedation-practices-of-expert-nurses-during-abortion-care
#3
Monica R McLemore, E Angel Aztlan
OBJECTIVE: To evaluate the provision of procedural sedation during abortion by expert nurses and to describe the factors that are associated with time to discharge for women who receive this sedation. DESIGN: Retrospective chart review. METHODS: Descriptive statistics were generated to describe a retrospective cohort of women presenting for abortion under procedural sedation. Analysis of variance was used to determine significant characteristics that influenced time to discharge...
July 17, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28727621/how-information-drives-complexity
#4
Thomas R Clancy
As systems evolve over time, their natural tendency is to become increasingly more complex. Studies in the field of complex systems have generated new perspectives on the application of management strategies in health systems. This article is the 2nd in a series of articles that focuses on why technological complexity is increasing and strategies nurse administrators can use to successfully implement change in the face of it.
July 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28727240/development-and-dissemination-of-the-el-centro-health-disparities-measures-library
#5
Victoria Behar Mitrani, Joanne E O'Day, Timothy B Norris, Oluwamuyiwa Winifred Adebayo
PURPOSE: This report describes the development and dissemination of a library of English measures, with Spanish translations, on constructs relevant to social determinants of health and behavioral health outcomes. The El Centro Measures Library is a product of the Center of Excellence for Health Disparities Research: El Centro, a program funded by the National Institute on Minority Health and Health Disparities of the U.S. National Institutes of Health. The library is aimed at enhancing capacity for minority health and health disparities research, particularly for Hispanics living in the United States and abroad...
July 20, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/28725840/the-impact-of-revised-discharge-instructions-on-patient-satisfaction
#6
Heather Markey Waniga, Travis Gerke, Alena Shoemaker, Derek Bourgoine, Pracha Eamranond
INTRODUCTION: The impact of discharge instructions on a patient's experience is not fully understood. This research explored whether nurse- and physician-generated discharge instructions had a positive effect on patient perceptions regarding their discharge experience. METHODS: We compared Press Ganey discharge-related patient satisfaction scores for the year prior to and the year subsequent to implementing revised discharge instructions for all patients admitted to a 180-bed community-based hospital...
September 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28723988/brazilian-research-groups-in-nursing-comparison-of-2006-and-2016-profiles
#7
Alacoque Lorenzini Erdmann, Caroline Cechinel Peiter, Gabriela Marcellino de Melo Lanzoni
Objective: To compare the profile of nursing research groups registered at the CNPq Research Groups Directory in 2006 and 2016. Method: Descriptive and documentary analysis, The data has been collected in 2006 and in 2016, with parameterized search with the term "nursing" at the CNPq Research Groups Directory. The selected variables have been organized in a Microsoft Office Exce spreadsheetl. Results: The research groups have increased from 251 in 2006 to 617 in 2016, with important increase of the number of participants, among students and researchers...
July 13, 2017: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/28722809/measuring-the-outcomes-of-nursing-practice-a-delphi-study
#8
Jenny Sim, Patrick Crookes, Kenneth Walsh, Elizabeth Halcomb
AIM: To develop nursing-sensitive patient indicators to measure the outcomes of nursing practice. BACKGROUND: Nurses play an important role in the health care system yet there is no consensus on how the impact of nursing work should be evaluated. Limited research has previously examined the views of clinical nurses on the important concepts for measuring nursing practice. DESIGN: A four-round modified Delphi survey sought opinions from patients and nurses about the relevant concepts and their relative priority as indicators of quality nursing practice...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28722784/the-universal-collaborative-dynamic-model-of-specialist-and-advanced-nursing-and-midwifery-practice-a-way-forward
#9
Laserina O'Connor, Mary Casey, Rita Smith, Gerard Michael Fealy, Denise O' Brien, Denise O'Leary, Diarmuid Stokes, Martin S McNamara, Mary Ellen Glasgow, Andrew Cashin
BACKGROUND: There is a sizable body of empirical literature supporting the unique contributions of specialist and advanced practice roles to health care. However, there is very little international evidence to inform the integration of a future model for advanced or specialist practice in the Irish health care system. AIM: The aim of this study was to inform and guide the development of a future model of specialist and advanced nursing and midwifery practice. DESIGN: A qualitative study was conducted to initiate this important area of inquiry...
July 19, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28722172/intentional-learning-a-concept-analysis
#10
Sarah Mollman, Lori Candela
AIM: To use a concept analysis to determine a clear definition of the term "intentional learning" for use in nursing. BACKGROUND: The term intentional learning has been used for years in educational, business, and even nursing literature. It has been used to denote processes leading to higher order thinking and the ability to use knowledge in new situations; both of which are important skills to develop in nursing students. But the lack of a common, accepted definition of the term makes it difficult for nurse educators to base instruction and learning experiences on or to evaluate its overall effectiveness in educating students for diverse, fast-paced clinical practices...
July 19, 2017: Nursing Forum
https://www.readbyqxmd.com/read/28720751/exploring-the-perspectives-of-clinical-professionals-and-support-staff-on-implementing-supported-self-management-for-asthma-in-uk-general-practice-an-imp-2-art-qualitative-study
#11
Susan Morrow, Luke Daines, Sharon Wiener-Ogilvie, Liz Steed, Lorna McKee, Ann-Louise Caress, Stephanie J C Taylor, Hilary Pinnock
Despite an overwhelming evidence base, supported self-management of asthma is poorly implemented into routine practice. Strategies for implementation must address organisational routines, as well as provide resources for patients and training to improve professionals' skills. We aimed to explore the priority that primary care practices attach to asthma self-management, to describe their existing asthma management routines, and to generate innovative implementation strategies. We recruited 33 participants (23 general practitioners; seven nurses; three administrative staff) from 14 general practices...
July 18, 2017: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/28720631/accrued-cost-savings-of-a-free-clinic-using-quality-adjusted-life-years-saved-and-return-on-investment
#12
Jim Sanders, Marcus Lacey, Clare E Guse
INTRODUCTION: Savings garnered through the provision of preventive services is a form of profit for health systems. Free clinics have been using this logic to demonstrate their cost-savings. The Community-Based Chronic Disease Management (CCDM) clinic treats hypertension using nurse-led teams, clinical protocols, and community-based settings. METHODS: We calculated CCDM's cost-effectiveness from 2007 to 2013 using 2 metrics: Quality-adjusted life years (QALYs) saved and return on investment (ROI)...
July 2017: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/28720263/aiming-for-a-holistic-integrated-service-for-men-diagnosed-with-prostate-cancer-definitions-of-standards-and-skill-sets-for-nurses-and-allied-healthcare-professionals
#13
Alastair D Lamb, Sue Thompson, Netty Kinsella, Ingmar Gerbitz, Elaine Chapman, Lisa Putt, Sophie Bennett, Vineetha Thankappannair, Lisa Geoghegan, Naomi Wright, Alison Stirton-Croft, Penny Nixon, Andrew Styling, Diane Whitney, Lindsay Hodgson, Lisa Punt, Jenny Longmore, Mike Carter, Bill Petch, Yvonne Rimmer, Simon Russell, Luke Hughes-Davies, Danish Mazhar, Nimish C Shah, Vincent J Gananapragasam, Andrew Doble, Ola Bratt, Christof Kastner
PURPOSE: To establish a comprehensive set of recommendations for the service structure and skill set of nurses and allied healthcare professionals in prostate cancer care. METHODS: Using components of formal consensus methodology, a 30-member multidisciplinary panel produced 53 items for discussion relating to the provision of care for prostate cancer patients by specialist nurses and allied healthcare professionals. Items were developed by two rounds of email correspondence in which, first, items were generated and, second, items refined to form the basis of a consensus meeting which constituted the third round of review...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28716313/telemedicine-for-management-of-inflammatory-bowel-disease-myibdcoach-a-pragmatic-multicentre-randomised-controlled-trial
#14
Marin J de Jong, Andrea E van der Meulen-de Jong, Mariëlle J Romberg-Camps, Marco C Becx, Jeroen P Maljaars, Mia Cilissen, Ad A van Bodegraven, Nofel Mahmmod, Tineke Markus, Wim M Hameeteman, Gerard Dijkstra, Ad A Masclee, Annelies Boonen, Bjorn Winkens, Astrid van Tubergen, Daisy M Jonkers, Marie J Pierik
BACKGROUND: Tight and personalised control of inflammatory bowel disease in a traditional setting is challenging because of the disease complexity, high pressure on outpatient clinics, and rising incidence. We compared the effects of self-management with a telemedicine system, which was developed for all subtypes of inflammatory bowel disease, on health-care utilisation and patient-reported quality of care versus standard care. METHODS: We did this pragmatic, randomised trial in two academic and two non-academic hospitals in the Netherlands...
July 14, 2017: Lancet
https://www.readbyqxmd.com/read/28714835/interventions-to-support-and-develop-clinician-researcher-leadership-in-one-health-district
#15
Margaret Fry, Anthony Dombkins
Purpose Clinical leadership, researcher capacity and a culture of clinical inquiry are needed in the clinical workforce. The purpose of this paper is to report on a program which was used to develop and support clinicians to explore practice, implement innovation, translate evidence and build researcher capacity. Design/methodology/approach This pragmatic paper presents a case study of a nursing and midwifery clinician-researcher development program. The multi-site, multi-modal program focused on education, mentoring and support, communication networks, and clinician-university partnerships strategies to build workforce capacity and leadership...
July 10, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28714447/feasibility-of-automating-patient-acuity-measurement-using-a-machine-learning-algorithm
#16
Caitlin W Brennan, Frank Meng, Mark M Meterko, Leonard W D'Avolio
BACKGROUND AND PURPOSE: One method of determining nurse staffing is to match patient demand for nursing care (patient acuity) with available nursing staff. This pilot study explored the feasibility of automating acuity measurement using a machine learning algorithm. METHODS: Natural language processing combined with a machine learning algorithm was used to predict acuity levels based on electronic health record data. RESULTS: The algorithm was able to predict acuity relatively well...
December 1, 2016: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28714441/nurses-attitudes-regarding-the-safe-handling-of-patients-who-are-morbidly-obese-instrument-development-and-psychometric-analysis
#17
Susan Bejciy-Spring, Brenda Vermillion, Sally Morgan, Cheryl Newton, Sheila Chucta, Cindy Gatens, Inga Zadvinskis, Christopher Holloman, Esther Chipps
BACKGROUND AND PURPOSE: Nurses' attitudes play an important role in the consistent practice of safe patient handling behaviors. The purposes of this study were to develop and assess the psychometric properties of a newly developed instrument measuring attitudes of nurses related to the care and safe handling of patients who are obese. METHODS: Phases of instrument development included (a) item generation, (b) content validity assessment, (c) reliability assessment, (d) cognitive interviewing, and (e) construct validity assessment through factor analysis...
December 1, 2016: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/28714150/development-and-psychometric-testing-of-a-new-instrument-to-measure-the-caring-behaviour-of-nurses-in-italian-acute-care-settings
#18
Michela Piredda, Valerio Ghezzi, Elisa Fenizia, Anna Marchetti, Tommasangelo Petitti, Maria Grazia De Marinis, Alessandro Sili
AIM: To develop and psychometrically test the Italian-language Nurse Caring Behaviours Scale, a short measure of nurse caring behaviour as perceived by inpatients. BACKGROUND: Patient perceptions of nurses' caring behaviours are a predictor of care quality. Caring behaviours are culture-specific, but no measure of patient perceptions has previously been developed in Italy. Moreover, existing tools show unclear psychometric properties, are burdensome for respondents, or are not widely applicable...
July 16, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28713073/dementia-friendly-interventions-to-improve-the-care-of-people-living-with-dementia-admitted-to-hospitals-a-realist-review
#19
Melanie Handley, Frances Bunn, Claire Goodman
OBJECTIVES: To identify features of programmes and approaches to make healthcare delivery in secondary healthcare settings more dementia-friendly, providing a context-relevant understanding of how interventions achieve outcomes for people living with dementia. DESIGN: A realist review conducted in three phases: (1) stakeholder interviews and scoping of the literature to develop an initial programme theory for providing effective dementia care; (2) structured retrieval and extraction of evidence; and (3) analysis and synthesis to build and refine the programme theory...
July 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28711216/national-nursing-science-priorities-creating-a-shared-vision
#20
Patricia Eckardt, Joan M Culley, Elizabeth Corwin, Therese Richmond, Cynthia Dougherty, Rita H Pickler, Cheryl A Krause-Parello, Carol F Roye, Jessica G Rainbow, Holli A DeVon
BACKGROUND: Nursing science is essential to advance population health through contributions at all phases of scientific inquiry. Multiple scientific initiatives important to nursing science overlap in aims and population focus. PURPOSE: This article focused on providing the American Academy of Nursing and nurse scientists in the Unites States with a blueprint of nursing science priorities to inform a shared vision for future collaborations, areas of scientific inquiry, and resource allocation...
June 12, 2017: Nursing Outlook
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