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Critical appraisal

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https://www.readbyqxmd.com/read/29350586/mass-media-representations-of-the-evidence-as-a-possible-deterrent-to-recommending-exercise-for-the-treatment-of-depression-lessons-five-years-after-the-extraordinary-case-of-tread-uk
#1
Panteleimon Ekkekakis, Mark E Hartman, Matthew A Ladwig
Exercise or physical activity are recommended options within stepped-care treatment models for depression. However, few physicians present these options to patients, in part because of the impression that the supporting evidence is weak or inconsistent. We speculate that the coocurrence of "counter-messaging" and deficient critical appraisal may lead to such impressions. We focus on TREAD-UK (ISRCTN16900744), the largest trial to investigate "whether physical activity can be an effective treatment for depression within primary care"...
January 19, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29350073/in-their-own-words-a-synthesis-of-the-qualitative-research-on-the-experiences-of-adults-seeking-asylum-a-systematic-review-of-qualitative-findings-in-forced-migration
#2
Thomas Hoare, Andrew Vidgen, Neil Roberts
Quantitative research indicates that some forced migrants have mental health needs. Asylum seekers are a group of forced migrants applying for asylum status in a host country, and are often subject to rights restrictions and threat of deportation, though little is known about subjective experiences of the asylum journey and process of claiming asylum. The current paper therefore describes a systematic review of the qualitative literature, examining asylum seekers experiences of asylum journey, from country of origin, to arrival and adaptation to host countries...
December 2017: Medicine, Conflict, and Survival
https://www.readbyqxmd.com/read/29349639/outcomes-in-syncope-research-a-systematic-review-and-critical-appraisal
#3
Monica Solbiati, Viviana Bozzano, Franca Barbic, Giovanni Casazza, Franca Dipaola, James V Quinn, Matthew J Reed, Robert S Sheldon, Win-Kuang Shen, Benjamin C Sun, Venkatesh Thiruganasambandamoorthy, Raffaello Furlan, Giorgio Costantino
Syncope is the common clinical manifestation of different diseases, and this makes it difficult to define what outcomes should be considered in prognostic studies. The aim of this study is to critically analyze the outcomes considered in syncope studies through systematic review and expert consensus. We performed a systematic review of the literature to identify prospective studies enrolling consecutive patients presenting to the Emergency Department with syncope, with data on the characteristics and incidence of short-term outcomes...
January 18, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29348924/mortality-and-hospitalizations-in-intensive-dialysis-a-systematic-review-and-meta-analysis
#4
Anna Mathew, Jody-Ann McLeggon, Nirav Mehta, Samuel Leung, Valerie Barta, Thomas McGinn, Gihad Nesrallah
Background: Survival and hospitalization are critically important outcomes considered when choosing between intensive hemodialysis (HD), conventional HD, and peritoneal dialysis (PD). However, the comparative effectiveness of these modalities is unclear. Objective: We had the following aims: (1) to compare the association of mortality and hospitalization in patients undergoing intensive HD, compared with conventional HD or PD and (2) to appraise the methodological quality of the supporting evidence...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29348109/review-beyond-conventional-therapies-complementary-and-alternative-medicine-in-the-management-of-hypertension-an-evidence-based-review
#5
Ang Peng Wong, Yaman Walid Kassab, Abdul Latiff Mohamed, Amelah Mohammed Abdul Qader
Hypertension is one of the major causes of morbidity and mortality. Worldwide, Hypertension is estimated to cause 7.5 million deaths, about 12.8% of the total of all deaths. This accounts for 57 million disability adjusted life years (DALYS) or 3.7% of total DALYS. This led WHO to set a target of 25% reduction in prevalence by 2025. To reach that, WHO has adopted non-conventional methods for the management of hypertension? Despite worldwide popularity of such non-conventional therapies, only small volume of evidence exists that supports its effectiveness...
January 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29347927/prevalence-of-hypertensive-disorders-of-pregnancy-in-ethiopia-a-systemic-review-and-meta-analysis
#6
Abadi Kidanemariam Berhe, Getachew Mullu Kassa, Gedefaw Abeje Fekadu, Achenef Asmamaw Muche
BACKGROUND: Although hypertensive disorders of pregnancy are the leading cause of poor perinatal outcomes in Ethiopia, there is no study that shows the national prevalence. Therefore, the aim of this study was to estimate the national pooled prevalence of hypertensive disorders of pregnancy from studies conducted in different parts of the country. METHODS: Databases; MEDLINE, PubMed, HINARI, EMBASE, Google Scholar and African Journals Online were searched by using different search terms on HDP and Ethiopia...
January 18, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29344794/ticagrelor-for-secondary-prevention-of-atherothrombotic-events-after-myocardial-infarction-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#7
REVIEW
Xavier G L V Pouwels, Robert Wolff, Bram L T Ramaekers, Anoukh Van Giessen, Shona Lang, Steve Ryder, Gill Worthy, Steven Duffy, Nigel Armstrong, Jos Kleijnen, Manuela A Joore
The National Institute for Health and Care Excellence (NICE) invited AstraZeneca, the manufacturer of ticagrelor (Brilique®), to submit evidence on the clinical and cost effectiveness of ticagrelor 60 mg twice daily (BID) in combination with low-dose aspirin [acetylsalicylic acid (ASA)] compared with ASA only for secondary prevention of atherothrombotic events in patients with a history of myocardial infarction (MI) and who are at increased risk of atherothrombotic events. Kleijnen Systematic Reviews Ltd (KSR), in collaboration with Maastricht University Medical Centre+, was commissioned as the evidence review group (ERG)...
January 18, 2018: PharmacoEconomics
https://www.readbyqxmd.com/read/29344682/68ga-prostate-specific-membrane-antigen-psma-positron-emission-tomography-pet-for-primary-staging-of-high-risk-prostate-cancer-a-systematic-review
#8
Julia Corfield, Marlon Perera, Damien Bolton, Nathan Lawrentschuk
PURPOSE: To systematically review currently available data on 68Ga-prostate specific membrane antigen (PSMA) positron emission tomography (PET) used for the primary staging of high-risk prostate cancer. METHODS: We performed critical reviews of EMBASE, Web of Science (including MEDLINE) and Cochrane databases in October 2016 according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement. We included studies that utilized 68Ga-PSMA PET for primary staging of prostate cancer...
January 17, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29343048/physiology-intervention-and-outcome-three-critical-questions-about-cerebral-tissue-oxygen-saturation-monitoring
#9
Lingzhong Meng, Shaun E Gruenbaum, Feng Dai, Tianlong Wang
The balance between cerebral tissue oxygen consumption and supply can be continuously assessed by cerebral tissue oxygen saturation (SctO2) monitor. A construct consisting of three sequential questions, targeting the physiology monitored, the intervention implemented, and the outcomes affected, is proposed to critically appraise this monitor. The impact of the SctO2- guided care on patient outcome was examined through a systematic literature search and meta- analysis. We concluded that the physiology monitored by SctO2 is robust and dynamic, fragile (prone to derangement), and adversely consequential when deranged...
January 17, 2018: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29341442/motivating-influences-and-ability-based-outcomes-of-dental-hygiene-baccalaureate-education-in-canada
#10
Z Kanji, D M Laronde
BACKGROUND: There is a scarcity of studies on Canadian baccalaureate dental hygienists. As discussions about baccalaureate education for dental hygiene continue on a national level, examining outcomes of earning a dental hygiene degree is paramount. OBJECTIVE: To investigate the motivating reasons and ability-based outcomes of earning a Bachelor of Dental Science in Dental Hygiene (BDSc) degree from the University of British Columbia (UBC), Canada. METHODS: UBC dental hygiene entry-to-practice (ETP) and degree-completion (DC) graduates (n = 116; 32%) from 1994 to 2016 participated in an online mixed-methods survey...
January 17, 2018: International Journal of Dental Hygiene
https://www.readbyqxmd.com/read/29341310/critical-appraisal-of-the-oxidative-stress-pathway-in-vitiligo-a-systematic-review-and-meta-analysis
#11
REVIEW
R Speeckaert, J Dugardin, J Lambert, H Lapeere, E Verhaeghe, M M Speeckaert, N van Geel
BACKGROUND: The pathogenesis of vitiligo remains a topic of extensive debate. This is partly due to the moderate efficacy of current treatments. The role of oxidative stress pathway in vitiligo is a popular although controversial research topic. OBJECTIVE: To clarify the role of the oxidative stress pathway in vitiligo compared to other inflammatory skin disorders and to assess the therapeutic role of antioxidants. METHODS: We conducted a systematic search of the existing literature on the aberrancies of the oxidative stress pathway in vitiligo...
January 17, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29340451/is-waste-collection-associated-with-hepatitis-b-infection-a-meta-analysis
#12
Marcos Paulo Gomes Mol, Sandy Cairncross, Dirceu Bartolomeu Greco, Leo Heller
This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientific discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were sought which had been made available on the data used by December 2013 and updated to December 2016. The quality of the included studies was assessed according to the guidelines of Loney et al. for the critical appraisal of studies on the prevalence or incidence of a health problem...
November 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29338767/effect-of-exercise-versus-cognitive-behavioural-therapy-or-no-intervention-on-anxiety-depression-fitness-and-quality-of-life-in-adults-with-previous-methamphetamine-dependency-a-systematic-review
#13
REVIEW
Linzette Morris, Jessica Stander, Wardah Ebrahim, Stephanie Eksteen, Orissa Anna Meaden, Ané Ras, Annemarie Wessels
BACKGROUND: Methamphetamine (MA) is a highly addictive psychostimulant used by approximately 52 million people worldwide. Chronic MA abuse leads to detrimental physiological and neurological changes, as well as increases in anxiety and depression, and decreases in overall fitness and quality of life. Exercise has been reported to possibly reverse physiological and neurological damage caused by previous MA use, and to reduce anxiety and depression in this population. The aim of this systematic review was to identify, clinically appraise and synthesise the available evidence for the effectiveness of exercise, compared to cognitive behavioural therapy (CBT), standard care or no intervention, on decreasing anxiety and depression and improving fitness and quality of life in previous MA users...
January 16, 2018: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29338099/establishing-the-critical-role-of-oriented-aggregation-in-molecular-solid-state-fluorescence-enhancement
#14
P Srujana, T P Radhakrishnan
The general occurrence of fluorescence emission quenching in molecular aggregates is circumvented in select classes of molecules. This has largely been attributed to the rigidification of the molecule and its environment, which hinders non-radiative excited state energy loss through structural relaxation; since such an effect should in principle apply to most aggregates and crystals, there must clearly be other critical factors that make the select molecules exceptional. Discovery of three crystalline structures of a new push-pull molecule in its enantiomorphic and racemic forms, exhibiting not only very high, but distinctly different solid state fluorescence enhancements, has now allowed a systematic investigation of the role of intramolecular and intermolecular excited state energy loss pathways...
January 16, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29337387/systematic-review-of-predictive-risk-models-for-adverse-drug-events-in-hospitalised-patients
#15
REVIEW
Nazanin Falconer, Michael Barras, Neil Cottrell
AIM: An emerging approach to reducing hospital adverse drug events is the use of predictive risk scores. The aim of this systematic review was to critically appraise models developed for predicting adverse drug event risk in inpatients. METHODS: Embase, PubMed, CINAHL and Scopus databases were used to identify studies of predictive risk models for hospitalised adult inpatients. Studies had to have used multivariable logistic regression for model development, resulting in a score or rule with two or more variables, to predict the likelihood of inpatient adverse drug events...
January 16, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29337007/postnatal-post-traumatic-stress-an-integrative-review
#16
Madeleine Simpson, Virginia Schmied, Cathy Dickson, Hannah Grace Dahlen
PROBLEM: Post-traumatic stress disorder and post-traumatic stress symptoms following birth occur amongst a small proportion of women but can lead to poor maternal mental health, impairment in mother-infant bonding and relationship stress. This integrative review aims to examine the associated risk factors and women's own experiences of postnatal post-traumatic stress in order to better understand this phenomenon. METHOD: Fifty three articles were included and critically reviewed using the relevant Critical Appraisal Skills Program checklists or Strengthening the Reporting of Observational studies in Epidemiology assessment tool...
January 11, 2018: Women and Birth: Journal of the Australian College of Midwives
https://www.readbyqxmd.com/read/29336515/expectations-and-experiences-of-patients-with-osteoarthritis-undergoing-total-joint-arthroplasty-an-integrative-review
#17
Min Ting Alicia See, Yanika Kowitlawakul, Apphia Jia Qi Tan, Sok Ying Liaw
BACKGROUND: The effectiveness of educational interventions for osteoarthritic patients undergoing total joint arthroplasty remains inconclusive. It is essential to understand the educational needs of these patients from their perspectives. AIM: The aim of this study was to systematically summarize and synthesize osteoarthritic patients' expectations and experiences in undergoing total joint arthroplasty to identify their educational needs. DESIGN: An integrative review was conducted...
January 16, 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29335899/the-ultrasonographic-whirlpool-sign-in-testicular-torsion-valuable-tool-or-waste-of-valuable-time-a-systematic-review-and-meta-analysis
#18
Jared McDowall, Ahmed Adam, Louis Gerber, Callistus O A Enyuma, Sunday J Aigbodion, Sean Buchanan, Abdullah E Laher
PURPOSE: A positive whirlpool sign (WS) is defined as the presence of a spiral-like pattern when the spermatic cord is assessed during ultrasonography (US), using standard, high-resolution ultrasonography (HRUS) and/or color Doppler sonography (CDS), in the presence of testicular torsion. The objective of this review was to assess the validity and accuracy of this sign by performing a comprehensive systematic literature review and meta-analysis. METHODS: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, a comprehensive literature search was performed (August, 2017), using the following databases: BMJ Best Practice, Cochrane Library, Embase, PubMed, Scopus, and Web of Science...
January 15, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29334943/training-programmes-to-improve-evidence-uptake-and-utilisation-by-physiotherapists-a-systematic-scoping-review
#19
Jessica Stander, Karen Grimmer, Yolandi Brink
BACKGROUND: Research training programmes are a knowledge translation (KT) intervention which aim to improve research evidence uptake by clinicians. Whilst KT training programmes have been reported to significantly improve evidence uptake by physiotherapists, it is unclear which aspects of training optimally assist KT into physiotherapy practice. The purpose of the review was to establish the body of evidence regarding KT training programmes to improve physiotherapists' use of evidence-based practice (EBP) and clinical practice guidelines (CPG)...
January 15, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29334280/comparison-of-guidelines-for-the-use-of-tnf-inhibitors-for-psoriasis-in-the-united-states-canada-europe-and-the-united-kingdom-a-critical-appraisal-and-comprehensive-review
#20
Vidhi V Shah, Erica B Lee, Shivani Reddy, Elaine J Lin, Jashin J Wu
PURPOSE: To compare and contrast evidence-based CPGs from leading dermatological organizations for the use of tumor necrosis factor inhibitors (TNFi) in psoriasis. MATERIALS AND METHODS: Guidelines from the British National Institute for Health and Care Excellence (NICE), the British Association of Dermatologists (BAD), the American Academy of Dermatology (AAD), the National Psoriasis Foundation (NPF), and the Canadian Dermatology Association (CDA) were reviewed and compared...
January 15, 2018: Journal of Dermatological Treatment
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