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Guideline development

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https://www.readbyqxmd.com/read/28455948/mobile-phone-text-messaging-to-improve-medication-adherence-in-secondary-prevention-of-cardiovascular-disease
#1
REVIEW
Alma J Adler, Nicole Martin, Javier Mariani, Carlos D Tajer, Onikepe O Owolabi, Caroline Free, Norma C Serrano, Juan P Casas, Pablo Perel
BACKGROUND: Worldwide at least 100 million people are thought to have prevalent cardiovascular disease (CVD). This population has a five times greater chance of suffering a recurrent cardiovascular event than people without known CVD. Secondary CVD prevention is defined as action aimed to reduce the probability of recurrence of such events. Drug interventions have been shown to be cost-effective in reducing this risk and are recommended in international guidelines. However, adherence to recommended treatments remains sub-optimal...
April 29, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28455578/-epidemiology-diagnostics-therapy-prevention-and-management-of-uncomplicated-bacterial-outpatient-acquired-urinary-tract-infections-in-adult-patients-update-2017-of-the-interdisciplinary-awmf-s3-guideline
#2
REVIEW
J Kranz, S Schmidt, C Lebert, L Schneidewind, W Vahlensieck, U Sester, R Fünfstück, S Helbig, W Hofmann, E Hummers, M Kunze, E Kniehl, K Naber, F Mandraka, B Mündner-Hensen, G Schmiemann, F M E Wagenlehner
BACKGROUND: Update of the 2010 published evidence-based S3 guideline on epidemiology, diagnostics, therapy and management of uncomplicated, bacterial, outpatient-acquired urinary tract infections in adult patients. The guideline contains current evidence for the rational use of antimicrobial substances, avoidance of inappropriate use of certain antibiotic classes and development of resistance. METHODOLOGY: The update was created under the leadership of the German Association of Urology (DGU)...
April 28, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28455279/engaging-patients-and-caregivers-managing-rare-diseases-to-improve-the-methods-of-clinical-guideline-development-a-research-protocol
#3
Dmitry Khodyakov, Kathi Kinnett, Sean Grant, Ann Lucas, Ann Martin, Brian Denger, Holly Peay, Ian Coulter, Arlene Fink
BACKGROUND: Clinical guidelines provide systematically developed recommendations for deciding on appropriate health care options for specific conditions and clinical circumstances. Up until recently, patients and caregivers have rarely been included in the process of developing care guidelines. OBJECTIVE: This project will develop and test a new online method for including patients and their caregivers in this process using Duchenne muscular dystrophy (DMD) care guidelines as an example...
April 28, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28454861/comparative-analysis-of-zonal-systems-for-macro-level-crash-modeling
#4
Qing Cai, Mohamed Abdel-Aty, Jaeyoung Lee, Naveen Eluru
INTRODUCTION: Macro-level traffic safety analysis has been undertaken at different spatial configurations. However, clear guidelines for the appropriate zonal system selection for safety analysis are unavailable. In this study, a comparative analysis was conducted to determine the optimal zonal system for macroscopic crash modeling considering census tracts (CTs), state-wide traffic analysis zones (STAZs), and a newly developed traffic-related zone system labeled traffic analysis districts (TADs)...
June 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28454796/atrial-fibrillation-detected-by-continuous-electrocardiographic-monitoring-using-implantable-loop-recorder-to-prevent-stroke-in-individuals-at-risk-the-loop-study-rationale-and-design-of-a-large-randomized-controlled-trial
#5
Søren Zöga Diederichsen, Ketil Jørgen Haugan, Lars Køber, Søren Højberg, Axel Brandes, Christian Kronborg, Claus Graff, Anders Gaarsdal Holst, Jonas Bille Nielsen, Derk Krieger, Jesper Hastrup Svendsen
Atrial fibrillation (AF) increases the rate of stroke 5-fold, and AF-related strokes have a poorer prognosis compared with non-AF-related strokes. Atrial fibrillation and stroke constitute an intensifying challenge, and health care organizations are calling for awareness on the topic. Previous studies have demonstrated that AF is often asymptomatic and consequently undiagnosed. The implantable loop recorder (ILR) allows for continuous, long-term electrocardiographic monitoring with daily transmission of arrhythmia information, potentially leading to improvement in AF detection and stroke prevention...
May 2017: American Heart Journal
https://www.readbyqxmd.com/read/28454614/guideline-implementation-surgical-smoke-safety
#6
Jennifer L Fencl
Research conducted during the past four decades has demonstrated that surgical smoke generated from the use of energy-generating devices in surgery contains toxic and biohazardous substances that present risks to perioperative team members and patients. Despite the increase in information available, however, perioperative personnel continue to demonstrate a lack of knowledge of these hazards and lack of compliance with recommendations for evacuating smoke during surgical procedures. The new AORN "Guideline for surgical smoke safety" provides guidance on surgical smoke management...
May 2017: AORN Journal
https://www.readbyqxmd.com/read/28454591/lost-in-translation-returning-germline-genetic-results-in-genome-scale-cancer-research
#7
Amber L Johns, Skye H McKay, Jeremy L Humphris, Mark Pinese, Lorraine A Chantrill, R Scott Mead, Katherine Tucker, Lesley Andrews, Annabel Goodwin, Conrad Leonard, Hilda A High, Katia Nones, Ann-Marie Patch, Neil D Merrett, Nick Pavlakis, Karin S Kassahn, Jaswinder S Samra, David K Miller, David K Chang, Marina Pajic, John V Pearson, Sean M Grimmond, Nicola Waddell, Nikolajs Zeps, Anthony J Gill, Andrew V Biankin
BACKGROUND: The return of research results (RoR) remains a complex and well-debated issue. Despite the debate, actual data related to the experience of giving individual results back, and the impact these results may have on clinical care and health outcomes, is sorely lacking. Through the work of the Australian Pancreatic Cancer Genome Initiative (APGI) we: (1) delineate the pathway back to the patient where actionable research data were identified; and (2) report the clinical utilisation of individual results returned...
April 28, 2017: Genome Medicine
https://www.readbyqxmd.com/read/28454589/prevalence-and-antimicrobial-resistance-profile-of-staphylococcus-in-dairy-farms-abattoir-and-humans-in-addis-ababa-ethiopia
#8
Takele Beyene, Halefom Hayishe, Fikru Gizaw, Ashenafi Feyisa Beyi, Fufa Abunna, Bedaso Mammo, Dinka Ayana, Hika Waktole, Reta Duguma Abdi
BACKGROUND: Staphylococcus species cause mastitis and wound infection in livestock and food poisoning in humans through ingestion of contaminated foods, including meat and dairy products. They are evolving pathogens in that they readily acquire drug resistance, and multiple drug-resistant (MDR) isolates are increasing in human and veterinary healthcare. Therefore, this study was conducted to evaluate the prevalence of Staphylococci and their drug resistance in dairy farms and abattoir settings of Addis Ababa...
April 28, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28454516/early-childhood-obesity-a-survey-of-knowledge-and-practices-of-physicians-from-the-middle-east-and-north-africa
#9
Inge Gies, Bader AlSaleem, Beheshteh Olang, Berkouk Karima, Gamal Samy, Khaled Husain, Mahmoud Elhalik, Mohamad Miqdady, Mohamad Rawashdeh, Mohamed Salah, Nezha Mouane, Pejman Rohani, Atul Singhal, Yvan Vandenplas
BACKGROUND: Childhood obesity is one of the most serious public health issues of the twenty-first century affecting even low- and middle-income countries. Overweight and obese children are more likely to stay obese into adulthood. Due to the paucity of data on local practices, our study aimed to assess the knowledge and practices of physicians from the Middle East and North Africa region with respect to early-onset obesity. METHODS: A specific questionnaire investigating the perception and knowledge on early-onset obesity was circulated to healthcare providers (general physicians, pediatricians, pediatric gastroenterologist, neonatologists) practicing in 17 Middle East and North African countries...
April 28, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28454445/role-of-reactive-oxygen-species-in-the-anticancer-activity-of-botanicals-comparing-sensitivity-profiles
#10
Zoya Cohen, Yair Maimon, Noah Samuels, Raanan Berger
Numerous botanicals have been shown to exhibit in vitro and in vivo anticancer activity, some of which is the result of the induction of reactive oxygen species (ROS) in cancer cells with a high ROS content. The present study compared sensitivities to a series of botanicals among cancer cell lines, using an XTT viability test, in order to create a specific cancer-herb profile. Of the 27 botanicals screened, 10 exhibited a cytotoxic effect, 7 of which were ROS-mediated. The sensitivity profiles of the ROS-inducing botanicals in 10 cancer cell lines were similar, unlike 3 cytotoxic ROS-independent botanicals that displayed divergent botanical-specific profiles...
April 2017: Oncology Letters
https://www.readbyqxmd.com/read/28454070/principles-and-applications-of-photoelectrochemical-sensing-strategies-based-on-biofunctionalized-nanostructures
#11
REVIEW
Yang Zang, Jianping Lei, Huangxian Ju
Photoelectrochemical (PEC) biosensing is a popular research hotspot that has attracted substantial attention from chemists and biologists due to its low cost and desirable sensitivity. The PEC biosensing mainly refers to the influence of the interaction between recognition element and analyte on photocurrent signal, which involves the charge and energy transfer of PEC reaction between electron donor/acceptor and photoactive material upon light irradiation. Understanding the fundamentals of PEC strategy benefits the development of next-generation PEC sensors...
April 22, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28453928/the-clinical-severity-of-hemoglobin-s-black-a-%C3%AE-%C3%AE-%C3%AE-0-thalassemia
#12
Maria I Cancio, Banu Aygun, David H K Chui, Jennifer A Rothman, J Paul Scott, Jeremie H Estepp, Jane S Hankins
Hemoglobin S/Black ((A) γδβ)(0) -thalassemia is a rare sickle cell disease (SCD) variant. On the basis of limited descriptions in the literature, the disease is reported as a mild microcytic anemia with an uncomplicated course. We report the clinical and laboratory data of nine patients whose diagnoses were confirmed by DNA-based techniques. Despite having mild anemia and high fetal hemoglobin level postinfancy, these patients developed many of the classic complications of SCD, including vaso-occlusive crisis, acute chest syndrome, avascular necrosis, and cholelithiasis...
April 28, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28453823/a-flowchart-for-building-evidence-based-care-bundles-in-intensive-care-based-on-a-systematic-review
#13
Marjon Borgert, Jan Binnekade, Frederique Paulus, Astrid Goossens, Dave Dongelmans
Purpose: The Institute for Healthcare Improvement is the founder of the care bundled approach and described the methods used on how to develop care bundles. However, other useful methods are published as well. In this systematic review, we identified what different methods were used to design care bundles in intensive care units. The results were used to build a comprehensive flowchart to guide through the care bundle design process. Data sources: Electronic databases were searched for eligible studies in PubMed, EMBASE and CINAHL from January 2001 to August 2014...
April 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28453809/in-patients-undergoing-lung-resection-is-it-safe-to-administer-amiodarone-either-as-prophylaxis-or-treatment-of-atrial-fibrillation
#14
Styliani Maria Kolokotroni, Levon Toufektzian, Leanne Harling, Andrea Billè
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether the administration of amiodarone is safe in patients undergoing lung resection either for prophylaxis or treatment of de novo postoperative atrial fibrillation (POAF). A total of 30 papers were identified, of which 13 represented the best evidence to answer the clinical question. The authors, journal, date, study type, country of publication, patient demographics, relevant outcomes and results were tabulated...
May 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28453627/patient-reported-physical-function-measures-in-cancer-clinical-trials
#15
Thomas M Atkinson, Angela M Stover, Daniel F Storfer, Rebecca M Saracino, Thomas A D'Agostino, Denise Pergolizzi, Konstantina Matsoukas, Yuelin Li, Ethan Basch
Patient-reported outcomes (PROs) are increasingly used to monitor treatment-related symptoms and physical function decrements in cancer clinical trials. As more patients enter survivorship, it is important to capture PRO physical function throughout trials to help restore pretreatment levels of function. We completed a systematic review of PRO physical function measures used in cancer clinical trials and evaluated their psychometric properties on the basis of guidelines from the US Food and Drug Administration...
April 27, 2017: Epidemiologic Reviews
https://www.readbyqxmd.com/read/28453588/-diverticular-disease-myths-and-realities
#16
Daniela Fluxá, Rodrigo Quera
Diverticulosis and diverticular disease of the colon are common conditions in Western countries. The incidence and prevalence of these diseases are increasing and becoming significant for health systems. A growing body of knowledge is shifting the paradigm of the pathogenesis and treatment of diverticular disease. Low-grade inflammation, altered intestinal microbiota, visceral hypersensitivity, and abnormal colonic motility have been identified as factors leading to diverticular disease. The risk of developing diverticulitis among individuals with diverticulosis is lower than 10 to 25%...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28452891/child-seat-belt-guidelines-examining-the-4-9-rule-as-the-standard-examining-the-4-9-rule-as-the-standard
#17
Amber M Morse, Mary E Aitken, Samantha H Mullins, Beverly K Miller, Mindy M Pomtree, Erin M Ulloa, Jeffrey S Montgomery, Marie E Saylors
BACKGROUND: Current American Academy of Pediatrics (AAP) recommendations regarding transition from child safety/booster seat to adult safety belt use indicate that children should be at least 4'9", 8 years old, or 80 pounds. Proper fit in the vehicle seat, assessed with a 5 point fit test, should also be met. While most children reach 4'9" around age 8, each child and vehicle presents a unique combination; thus a child may not fit appropriately in all vehicle types using only the 4'9" requirement...
April 27, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28452889/surgical-management-of-pancreatic-necrosis-a-practice-management-guideline-from-the-eastern-association-for-the-surgery-of-trauma
#18
Nathan T Mowery, Brandon R Bruns, Heather MacNew, Suresh Agarwal, Toby Enniss, Mansoor Khan, Weidun Alan Guo, Jeremy W Cannon, Matthew Lissauer, Therese M Duane, Amy N Hildreth, Peter Pappas, Lynn Gries, Meghann Kaiser, Bryce Robinson
BACKGROUND: Pancreatic or peripancreatic tissue necrosis confers substantial morbidity and mortality. New modalities have created a wide variation in approaches and timing of interventions for necrotizing pancreatitis. As acute care surgery evolves, its practitioners are increasingly being called upon to manage these complex patients. METHODS: A systematic review of the MEDLINE database using PubMed was performed. English language articles regarding pancreatic necrosis from 1980 to 2014 were included...
April 27, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28452630/financial-capacity-and-financial-exploitation-of-older-adults-research-findings-policy-recommendations-and-clinical-implications
#19
Stacey Wood, Peter A Lichtenberg
BACKGROUND: Financial exploitation (FE) of older adults is a social issue that is beginning to receive the attention that it deserves in the mediathanks to some high profile cases, but empirical research and clinical guidelines on the topic are just emerging. OBJECTIVE: Our review seeks to synthesize the current research in the area and develop a concentpual model. METHOD: In this review, we describes the significance of the problem, proposes a theoretical model for conceptualizing FE, and summarizes related areas of research that may be useful to consider in the understanding of FE...
January 2017: Clinical Gerontologist
https://www.readbyqxmd.com/read/28452607/how-do-patients-actually-experience-and-use-art-in-hospitals-the-significance-of-interaction-a-user-oriented-experimental-case-study
#20
Stine L Nielsen, Lars B Fich, Kirsten K Roessler, Michael F Mullins
This article aims to understand patient wellbeing and satisfaction and to qualify the current guidelines for the application of art in hospitals. Employing anthropological methods, we focus on the interactional aspects of art in health interventions. A user-oriented study ranked 20 paintings, followed by an experiment using paintings in the dayroom of five medical wards. Fieldwork was done over a two-week period. During the first week, dayrooms were configured without the presence of art and in the second week were configured with the artworks...
December 2017: International Journal of Qualitative Studies on Health and Well-being
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