keyword
MENU ▼
Read by QxMD icon Read
search

visual analytics

keyword
https://www.readbyqxmd.com/read/28227050/distance-metric-learning-using-random-forest-for-cytometry-data
#1
M Baran Pouyan, J Birjandtalab, M Nourani, M Baran Pouyan, J Birjandtalab, M Nourani, M Baran Pouyan, J Birjandtalab, M Nourani
Visualization and clustering of single-cell mass cytometry (CyTOF) data are analytic techniques to identify different cell types. Most of such techniques, such as Euclidean norm, lose their effectiveness when the data dimension increases due to the curse of dimensionality. In this paper, we propose a new cell distance (called CytoRFD) that works based on Random Forest (RF) concept. The experimental results show that the proposed distance can achieve a much higher quality and effectiveness in large data analysis than traditional metrics specially for CyTOF data...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28218975/stacking-transgenic-event-das-%C3%A3-15%C3%A3-7-1-alters-maize-composition-less-than-traditional-breeding
#2
Rod A Herman, Brandon J Fast, Peter N Scherer, Alyssa M Brune, Denise T de Cerqueira, Barry W Schafer, Ricardo D Ekmay, George G Harrigan, Greg A Bradfisch
The impact of crossing ("stacking") genetically modified (GM) events on maize-grain biochemical composition was compared with the impact of generating non-GM hybrids. The compositional similarity of seven GM stacks containing event DAS-Ø15Ø7-1 and their matched non-GM near-isogenic hybrids (iso-hybrids) was compared with the compositional similarity of concurrently grown non-GM hybrids and these same iso-hybrids. Scatter plots were used to visualize comparisons among hybrids and a coefficient of identity (percent of variation explained by line of identity) was calculated to quantify the relationships within analyte profiles...
February 20, 2017: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/28212089/streammap-smooth-dynamic-visualization-of-high-density-streaming-points
#3
Chenhui Li, George Baciu, Han Yu
Interactive visualization of streaming points for real-time scatterplots and linear blending of correlation patterns is increasingly becoming the dominant mode of visual analytics for both big data and streaming data from active sensors and broadcasting media. To better visualize and interact with inter-stream patterns, it is generally necessary to smooth out gaps or distortions in the streaming data. Previous approaches either animate the points directly or present a sampled static heatmap. We propose a new approach, called StreamMap, to smoothly blend high-density streaming points and create a visual flow that emphasizes the density pattern distributions...
February 13, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28208275/comprehensive-three-dimensional-gas-chromatography-with-time-of-flight-mass-spectrometry
#4
Nathanial E Watson, H Daniel Bahaghighat, Ke Cui, Robert E Synovec
Development of comprehensive, three-dimensional (3D) gas chromatography with time-of-flight mass spectrometric detection (GC(3)/TOFMS) is described. This instrument provides four dimensions (4D) of chemical selectivity and includes significant improvements to total selectivity (mass spectrometric and chromatographic), peak identification, and operational temperature range relative to previous models of the GC(3) reported. The new instrumental design and data output are evaluated and illustrated via two samples, a 115-component test mixture and a diesel fuel spiked with several compounds, for the purpose of illustrating the chemical selectivity benefits of this instrumental platform...
February 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28207239/analyzing-dna-nanotechnology-a-call-to-arms-for-the-analytical-chemistry-community
#5
Divita Mathur, Igor L Medintz
In order to fully realize the potential of DNA nanotechnology, it is crucial to overcome the lack of robust analytical techniques that continue to hinder the purification and characterization of DNA-based structures. In this Feature, we provide a snapshot of the current state of metrological techniques in DNA nanotechnology and look forward to emerging technologies that may offer new ways to probe and visualize these complex structures.
February 16, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28204887/determination-of-monoamine-neurotransmitters-in-zebrafish-danio-rerio-by-gas-chromatography-coupled-to-mass-spectrometry-with-a-two-step-derivatization
#6
Alvaro Aragon, Jessica Legradi, Ana Ballesteros-Gómez, Juliette Legler, Martin van Velzen, Jacob de Boer, Pim Leonards
A sensitive analytical method for the determination of monoamine neurotransmitters (MNTs) in zebrafish larvae was developed using gas chromatography coupled to mass spectrometry. Six MNTs were selected as target compounds for neurotoxicity testing. MNTs underwent a two-step derivatization with hexamethyldisilazane (HDMS) for O-silylation followed by N-methyl-bis-heptafluorobutyramide (MBHFBA) for N-perfluoroacylation. Derivatization conditions were optimized by an experimental design approach. Method validation showed linear calibration curves (r (2) > 0...
February 15, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28193066/proof-of-principle-of-rtlc-an-open-source-software-developed-for-image-evaluation-and-multivariate-analysis-of-planar-chromatograms
#7
Dimitri Fichou, Petar Ristivojević, Gertrud E Morlock
High-performance thin-layer chromatography (HPTLC) is an advantageous analytical technique for analysis of complex samples. Combined with multivariate data analysis, it turns out to be a powerful tool for profiling of many samples in parallel. So far, chromatogram analysis has been time-consuming and required the application of at least two software packages to convert HPTLC chromatograms into a numerical data matrix. Hence, this study aimed to develop a powerful, all in one open-source software for user-friendly image processing and multivariate analysis of HPTLC chromatograms...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28192423/elucidation-of-molecular-kinetic-schemes-from-macroscopic-traces-using-system-identification
#8
Miguel Fribourg, Diomedes E Logothetis, Javier González-Maeso, Stuart C Sealfon, Belén Galocha-Iragüen, Fernando Las-Heras Andrés, Vladimir Brezina
Overall cellular responses to biologically-relevant stimuli are mediated by networks of simpler lower-level processes. Although information about some of these processes can now be obtained by visualizing and recording events at the molecular level, this is still possible only in especially favorable cases. Therefore the development of methods to extract the dynamics and relationships between the different lower-level (microscopic) processes from the overall (macroscopic) response remains a crucial challenge in the understanding of many aspects of physiology...
February 13, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28190349/a-dual-color-quantum-dots-encoded-frit-based-immunoassay-for-visual-detection-of-aflatoxin-m1-and-pirlimycin-residues-in-milk
#9
Wenxiao Jiang, Natalia V Beloglazova, Pengjie Luo, Ping Guo, Guimiao Lin, Xiaomei Wang
Mycotoxins and antibacterial agents are the main chemical hazards that lead to several health problems. Nowadays, multiplex immunoassay is a primary goal throughout the world. Here, aflatoxin M1 and pirlimycin were selected as models, and a novel dual colorimetric encoded frit-based immunoassay was developed for simultaneously screening of aflatoxin M1 and pirlimycin residues in milk. This multiplex frit-based immunoassay combined two monoclonal antibodies in order to extend the spectrum of analytes, and to enable detection of two classes of analytes in a single test...
February 13, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28187892/interactive-radiographic-image-retrieval-system
#10
Malay Kumar Kundu, Manish Chowdhury, Sudeb Das
BACKGROUND AND OBJECTIVE: Content based medical image retrieval (CBMIR) systems enable fast diagnosis through quantitative assessment of the visual information and is an active research topic over the past few decades. Most of the state-of-the-art CBMIR systems suffer from various problems: computationally expensive due to the usage of high dimensional feature vectors and complex classifier/clustering schemes. Inability to properly handle the "semantic gap" and the high intra-class versus inter-class variability problem of the medical image database (like radiographic image database)...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28187416/feature-learning-applied-to-the-estimation-of-tensile-strength-at-break-in-polymeric-material-design
#11
Fiorella Cravero, María Jimena Martínez, Gustavo Esteban Vazquez, Mónica Fátima Díaz, Ignacio Ponzoni
Several feature extraction approaches for QSPR modelling in Cheminformatics are discussed in this paper. In particular, this work is focused on the use of these strategies for predicting mechanical properties, which are relevant for the design of polymeric materials. The methodology analysed in this study employs a feature learning method that uses a quantification process of 2D structural characterization of materials with the autoencoder method. Alternative QSPR models inferred for tensile strength at break (a well-known mechanical property of polymers) are presented...
November 27, 2016: Journal of Integrative Bioinformatics
https://www.readbyqxmd.com/read/28167844/current-methods-of-haemolysis-detection-and-reporting-as-a-source-of-risk-to-patient-safety-a-narrative-review
#12
REVIEW
Euan J McCaughey, Elia Vecellio, Rebecca Lake, Ling Li, Leslie Burnett, Douglas Chesher, Stephen Braye, Mark Mackay, Stephanie Gay, Tony C Badrick, Johanna I Westbrook, Andrew Georgiou
AIM: Haemolysis has a major impact on patient safety as the need for a replacement specimen increases the risk of injury and infection, delays test results and extends the duration of hospital stays. Consistency of haemolysis detection and reporting can facilitate the generation of benchmark data used to develop quality practices to monitor and reduce this leading cause of pre-analytical laboratory error. This review aims to investigate current methods of haemolysis detection and reporting...
December 2016: Clinical Biochemist. Reviews
https://www.readbyqxmd.com/read/28163918/health-system-performance-assessment-landscape-at-the-eu-level-a-structured-synthesis-of-actors-and-actions
#13
Nataša Perić, Maria M Hofmarcher-Holzhacker, Judit Simon
BACKGROUND: Many policy makers and other stakeholders in the EU have expressed interest in better understanding the performance of their own health systems to identify opportunities for improvement in effectiveness, efficiency and equity. Health system performance assessment (HSPA) has received considerable attention at EU level as an instrument to improve transparency and accountability. This is equally important for population health and sustainable health spending. The goal of this paper is to synthesise and map the current state and developments in the field of HSPA relevant in the EU context and by this aid the navigation in the growing HSPA system, understand the available tools and identify opportunities for improvement...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28153237/graphene-oxide-and-carboxylated-graphene-oxide-viable-two-dimensional-nanolabels-for-lateral-flow-immunoassays
#14
Li Yu, Peiwu Li, Xiaoxia Ding, Qi Zhang
Graphene oxide (GO) and carboxylated GO were used as labels for lateral flow immunoassays, instead of the conventionally used colloidal gold and colored latex labels. A sensor is demonstrated that enables fast screening for aflatoxin B1 (AFB1) as a model analyte using the antibody-GO complex as the recognition element. The visual limit of detection and cut-off value for AFB1 are 0.3 and 1ng/mL, respectively. It is shown that GO and carboxylated GO are viable black labels for use in lateral flow assays, one typical advantage being the saving cost (compared to the use of colloidal gold)...
April 1, 2017: Talanta
https://www.readbyqxmd.com/read/28152838/a-schematic-case-episode-format-to-aid-in-choosing-wisely
#15
B Brooke Mann, Jad Hayes, Lalan S Wilfong, Marcus A Neubauer
: 181 Background: The recommendations of the Choosing Wisely campaign are evidence -based strategies to reduce cost without sacrificing outcomes. Yet tying the recommendations to indicators of use at the physician and case level has been challenging. As practices become responsible for total cost of care, an easy to use analytic method to determine appropriate use will be critical. We here describe a tool for rapid assessment of individual cases to achieve that objective. METHODS: The population was a payer defined cohort of lung cancer patients treated at Texas Oncology (TxO)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152441/the-identification-of-markers-for-geoforensic-hplc-profiling-at-close-proximity-sites
#16
G McCulloch, L A Dawson, M J Brewer, R M Morgan
Soil is a highly transferable source of trace physical material that is both persistent in the environment and varied in composition. This inherent variability can provide useful information to determine the geographical origin of a questioned sample or when comparing and excluding samples, since the composition of soil is dependent on geographical factors such as climate, bedrock geology and land use. Previous studies have limited forensic relevance due to the requirement for large sample amounts and unrealistic differences between the land use and geographical location of the sample sites...
January 17, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28149785/objective-assessment-of-the-effect-of-pupil-size-upon-the-power-distribution-of-multifocal-contact-lenses
#17
Eleni Papadatou, Antonio J Del Águila-Carrasco, José J Esteve-Taboada, David Madrid-Costa, Alejandro Cerviño-Expósito
AIM: To analytically assess the effect of pupil size upon the refractive power distributions of different designs of multifocal contact lenses. METHODS: Two multifocal contact lenses of center-near design and one multifocal contact lens of center-distance design were used in this study. Their power profiles were measured using the NIMO TR1504 device (LAMBDA-X, Belgium). Based on their power profiles, the power distribution was assessed as a function of pupil size...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28147275/visualization-of-chromatin-decompaction-and-break-site-extrusion-as-predicted-by-statistical-polymer-modeling-of-single-locus-trajectories
#18
Assaf Amitai, Andrew Seeber, Susan M Gasser, David Holcman
Chromatin moves with subdiffusive and spatially constrained dynamics within the cell nucleus. Here, we use single-locus tracking by time-lapse fluorescence microscopy to uncover information regarding the forces that influence chromatin movement following the induction of a persistent DNA double-strand break (DSB). Using improved time-lapse imaging regimens, we monitor trajectories of tagged DNA loci at a high temporal resolution, which allows us to extract biophysical parameters through robust statistical analysis...
January 31, 2017: Cell Reports
https://www.readbyqxmd.com/read/28146120/a-paper-based-electrochromic-array-for-visualized-electrochemical-sensing
#19
Fengling Zhang, Tianyi Cai, Liang Ma, Liyuan Zhan, Hong Liu
We report a battery-powered, paper-based electrochromic array for visualized electrochemical sensing. The paper-based sensing system consists of six parallel electrochemical cells, which are powered by an aluminum-air battery. Each single electrochemical cell uses a Prussian Blue spot electrodeposited on an indium-doped tin oxide thin film as the electrochromic indicator. Each electrochemical cell is preloaded with increasing amounts of analyte. The sample activates the battery for the sensing. Both the preloaded analyte and the analyte in the sample initiate the color change of Prussian Blue to Prussian White...
January 31, 2017: Sensors
https://www.readbyqxmd.com/read/28144197/epidemiologic-investigation-of-dysentery-in-north-of-iran-use-of-geographic-information-system-gis
#20
Aliasghar Nadi, Ghassem Abedi, Khatoon Isazadeh, Farideh Rostami, Hasan Siamian, Mahbobeh Hosseini, Mehran Asadi-Aliabadi
INTRODUCTION: Dysentery is an intestinal inflammation which is created by the microorganisms attacking intestine mucus. Knowing the prevalence of this disease in different societies paves the way for programming and providing treatment and preventive measures. The main purpose of this study is to investigate the epidemiologic pattern and geographical distribution of dysentery based on GIS. METHOD: This was a cross-sectional and analytical study. The dysentery cases were gathered from the section of contagious diseases in health chancellery of Mazandaran University of medical sciences through a checklist during the years 2008 to 2013...
December 2016: Materia Socio-medica
keyword
keyword
111709
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"