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https://www.readbyqxmd.com/read/28734360/revealing-the-biography-of-a-hidden-medieval-manuscript-using-synchrotron-and-conventional-imaging-techniques
#1
E Pouyet, S Devine, T Grafakos, R Kieckhefer, J Salvant, L Smieska, A Woll, A Katsaggelos, O Cossairt, M Walton
Reading the content of hidden texts from ancient manuscripts has become an increasingly important endeavor thanks to the variety of non-destructive analytical tools and image processing routines available for this task. In this study, portable macro X-Ray Fluorescence (MA-XRF-tube), Visible Hyperspectral Imaging (HSI) together with Synchrotron based macro X-Ray Fluorescence (MA-XRF-SR) are combined with signal processing methods to reveal the biography of a degraded manuscript recycled as binding material for a 16th century printed edition of Hesiod's Works and Days...
August 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28734172/clear-evidence-for-item-limits-in-visual-working-memory
#2
Kirsten C S Adam, Edward K Vogel, Edward Awh
There is a consensus that visual working memory (WM) resources are sharply limited, but debate persists regarding the simple question of whether there is a limit to the total number of items that can be stored concurrently. Zhang and Luck (2008) advanced this debate with an analytic procedure that provided strong evidence for random guessing responses, but their findings can also be described by models that deny guessing while asserting a high prevalence of low precision memories. Here, we used a whole report memory procedure in which subjects reported all items in each trial and indicated whether they were guessing with each response...
July 19, 2017: Cognitive Psychology
https://www.readbyqxmd.com/read/28734164/cognitive-strategies-in-the-mental-rotation-task-revealed-by-eeg-spectral-power
#3
Aaron L Gardony, Marianna D Eddy, Tad T Brunyé, Holly A Taylor
The classic mental rotation task (MRT; Shepard & Metzler, 1971) is commonly thought to measure mental rotation, a cognitive process involving covert simulation of motor rotation. Yet much research suggests that the MRT recruits both motor simulation and other analytic cognitive strategies that depend on visuospatial representation and visual working memory (WM). In the present study, we investigated cognitive strategies in the MRT using time-frequency analysis of EEG and independent component analysis. We scrutinized sensorimotor mu (µ) power reduction, associated with motor simulation, parietal alpha (pα) power reduction, associated with visuospatial representation, and frontal midline theta (fmθ) power enhancement, associated with WM maintenance and manipulation...
July 19, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28723903/automatic-analysis-and-3d-modelling-of-hi-c-data-using-tadbit-reveals-structural-features-of-the-fly-chromatin-colors
#4
François Serra, Davide Baù, Mike Goodstadt, David Castillo, Guillaume Filion, Marc A Marti-Renom
The sequence of a genome is insufficient to understand all genomic processes carried out in the cell nucleus. To achieve this, the knowledge of its three-dimensional architecture is necessary. Advances in genomic technologies and the development of new analytical methods, such as Chromosome Conformation Capture (3C) and its derivatives, provide unprecedented insights in the spatial organization of genomes. Here we present TADbit, a computational framework to analyze and model the chromatin fiber in three dimensions...
July 19, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28723249/experiences-of-individuals-with-visual-impairments-in-integrated-physical-education-a-retrospective-study
#5
Justin A Haegele, Xihe Zhu
PURPOSE: The purpose of this retrospective study was to examine the experiences of adults with visual impairments during school-based integrated physical education (PE). METHOD: An interpretative phenomenological analysis (IPA) research approach was used and 16 adults (ages 21-48 years; 10 women, 6 men) with visual impairments acted as participants for this study. The primary sources of data were semistructured audiotaped telephone interviews and reflective field notes, which were recorded during and immediately following each interview...
July 19, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28722604/classification-and-visualization-of-physical-and-chemical-properties-of-falsified-medicines-with-handheld-raman-spectroscopy-and-x-ray-computed-tomography
#6
Tomoko Kakio, Naoko Yoshida, Susan Macha, Kazunobu Moriguchi, Takashi Hiroshima, Yukihiro Ikeda, Hirohito Tsuboi, Kazuko Kimura
Analytical methods for the detection of substandard and falsified medical products (SFs) are important for public health and patient safety. Research to understand how the physical and chemical properties of SFs can be most effectively applied to distinguish the SFs from authentic products has not yet been investigated enough. Here, we investigated the usefulness of two analytical methods, handheld Raman spectroscopy (handheld Raman) and X-ray computed tomography (X-ray CT), for detecting SFs among oral solid antihypertensive pharmaceutical products containing candesartan cilexetil as an active pharmaceutical ingredient (API)...
June 19, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28722291/assessment-of-hair-surface-roughness-using-quantitative-image-analysis
#7
K H Park, H J Kim, B Oh, E Lee, J Ha
BACKGROUND/PURPOSE: Focus on the hair and hair cuticle is increasing. The hair cuticle is the first layer to be exposed to damage and the area of primary protection. For such reasons, hair product manufacturers consider cuticle protection important. However, previous studies used only visual assessment to examine the cuticle. This study aimed to obtain the changes in cuticles and measure hair roughness using a HIROX microscope. METHODS: A total of 23 female subjects used the same products daily for 4 weeks...
July 19, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28719613/visual-detection-of-brucella-in-bovine-biological-samples-using-dna-activated-gold-nanoparticles
#8
Dheeraj Pal, Nongthombam Boby, Satish Kumar, Gurpreet Kaur, Syed Atif Ali, Julien Reboud, Sameer Shrivastava, Praveen K Gupta, Jonathan M Cooper, Pallab Chaudhuri
Brucellosis is a bacterial disease, which, although affecting cattle primarily, has been associated with human infections, making its detection an important challenge. The existing gold standard diagnosis relies on the culture of bacteria which is a lengthy and costly process, taking up to 45 days. New technologies based on molecular diagnosis have been proposed, either through dip-stick, immunological assays, which have limited specificity, or using nucleic acid tests, which enable to identify the pathogen, but are impractical for use in the field, where most of the reservoir cases are located...
2017: PloS One
https://www.readbyqxmd.com/read/28711233/review-of-sleep-eeg-in-preterm-and-term-neonates
#9
Anneleen Dereymaeker, Kirubin Pillay, Jan Vervisch, Maarten De Vos, Sabine Van Huffel, Katrien Jansen, Gunnar Naulaers
Neonatal sleep is a crucial state that involves endogenous driven brain activity, important for neuronal survival and guidance of brain networks. Sequential EEG-sleep analysis in preterm infants provides insights into functional brain integrity and can document deviations of the biologically pre-programmed process of sleep ontogenesis during the neonatal period. Visual assessment of neonatal sleep-EEG, with integration of both cerebral and non-cerebral measures to better define neonatal state, is still considered the gold standard...
July 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28706547/factors-related-to-women-s-childbirth-satisfaction-in-physiologic-and-routine-childbirth-groups
#10
Elham Jafari, Parvin Mohebbi, Saeideh Mazloomzadeh
BACKGROUND: Women's satisfaction with childbirth is an important measure of the quality of maternity care services. This study aims to address factors related to women's childbirth satisfaction in physiological and routine childbirth groups. MATERIALS AND METHODS: This descriptive-analytical study was conducted among 340 women in physiological and routine childbirth groups in 2012. Women were selected through convenience sampling method in the routine group and by census in the physiological group...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28704193/rehabilitation-of-patients-with-hip-joint-arthroplasty-late-post-surgery-period-hospital-rehabilitation
#11
Maya S Krastanova, Elena M Ilieva, Danelina E Vacheva
BACKGROUND: Hip joint replacement (endoprosthesis, alloplasty) has become one of the most frequent surgery interventions of the 20th century. AIM: To conduct rehabilitation therapy in the late post-surgery period of hospital rehabilitation (45 days after surgery), to track patients' progress and measure the results. MATERIALS AND METHODS: One hundred and fifty-two patients with hip joint endoprosthesis were included in the study. All underwent surgery and rehabilitation at the Department of Clinical Rehabilitation of the Physical and Rehabilitation Medicine Clinic at Doctor G...
June 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28702459/a-review-of-quantitative-tools-used-to-assess-the-epidemiology-of-porcine-reproductive-and-respiratory-syndrome-in-u-s-swine-farms-using-dr-morrison-s-swine-health-monitoring-program-data
#12
REVIEW
Carles Vilalta, Andreia G Arruda, Steven J P Tousignant, Pablo Valdes-Donoso, Petra Muellner, Ulrich Muellner, Moh A Alkhamis, Robert B Morrison, Andres M Perez
Porcine reproductive and respiratory syndrome (PRRS) causes far-reaching financial losses to infected countries and regions, including the U.S. The Dr. Morrison's Swine Health Monitoring Program (MSHMP) is a voluntary initiative in which producers and veterinarians share sow farm PRRS status weekly to contribute to the understanding, in quantitative terms, of PRRS epidemiological dynamics and, ultimately, to support its control in the U.S. Here, we offer a review of a variety of analytic tools that were applied to MSHMP data to assess disease dynamics in quantitative terms to support the decision-making process for veterinarians and producers...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28701812/next-generation-data-systems-and-knowledge-products-to-support-agricultural-producers-and-science-based-policy-decision-making
#13
Susan M Capalbo, John M Antle, Clark Seavert
Research on next generation agricultural systems models shows that the most important current limitation is data, both for on-farm decision support and for research investment and policy decision making. One of the greatest data challenges is to obtain reliable data on farm management decision making, both for current conditions and under scenarios of changed bio-physical and socio-economic conditions. This paper presents a framework for the use of farm-level and landscape-scale models and data to provide analysis that could be used in NextGen knowledge products, such as mobile applications or personal computer data analysis and visualization software...
July 2017: Agricultural Systems
https://www.readbyqxmd.com/read/28701760/synovial-tissue-research-a-state-of-the-art-review
#14
REVIEW
Carl Orr, Elsa Sousa, David L Boyle, Maya H Buch, Christopher D Buckley, Juan D Cañete, Anca I Catrina, Ernest H S Choy, Paul Emery, Ursula Fearon, Andrew Filer, Danielle Gerlag, Frances Humby, John D Isaacs, Søren A Just, Bernard R Lauwerys, Benoit Le Goff, Antonio Manzo, Trudy McGarry, Iain B McInnes, Aurélie Najm, Constantino Pitzalis, Arthur Pratt, Malcolm Smith, Paul P Tak, Rogier Thurlings, João E Fonseca, Douglas J Veale
The synovium is the major target tissue of inflammatory arthritides such as rheumatoid arthritis. The study of synovial tissue has advanced considerably throughout the past few decades from arthroplasty and blind needle biopsy to the use of arthroscopic and ultrasonographic technologies that enable easier visualization and improve the reliability of synovial biopsies. Rapid progress has been made in using synovial tissue to study disease pathogenesis, to stratify patients, to discover biomarkers and novel targets, and to validate therapies, and this progress has been facilitated by increasingly diverse and sophisticated analytical and technological approaches...
August 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28697812/imaging-and-lipidomics-methods-for-lipid-analysis-in-metabolic-and-cardiovascular-disease
#15
K G Stevens, C A Bader, A Sorvina, D A Brooks, S E Plush, J L Morrison
Cardiometabolic diseases exhibit changes in lipid biology, which is important as lipids have critical roles in membrane architecture, signalling, hormone synthesis, homoeostasis and metabolism. However, Developmental Origins of Health and Disease studies of cardiometabolic disease rarely include analysis of lipids. This short review highlights some examples of lipid pathology and then explores the technology available for analysing lipids, focussing on the need to develop imaging modalities for intracellular lipids...
July 12, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28692978/keshif-rapid-and-expressive-tabular-data-exploration-for-novices
#16
Mehmet Adil Yalcin, Niklas Elmqvist, Benjamin B Bederson
General purpose graphical interfaces for data exploration are typically based on manual visualization and interaction specifications. While designing manual specification can be very expressive, it demands high efforts to make effective decisions, therefore reducing exploratory speed. Instead, principled automated designs can increase exploratory speed, decrease learning efforts, help avoid ineffective decisions, and therefore better support data analytics novices. Towards these goals, we present Keshif, a new systematic design for tabular data exploration...
July 4, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28690426/graphing-trillions-of-triangles
#17
Paul Burkhardt
The increasing size of Big Data is often heralded but how data are transformed and represented is also profoundly important to knowledge discovery, and this is exemplified in Big Graph analytics. Much attention has been placed on the scale of the input graph but the product of a graph algorithm can be many times larger than the input. This is true for many graph problems, such as listing all triangles in a graph. Enabling scalable graph exploration for Big Graphs requires new approaches to algorithms, architectures, and visual analytics...
July 2017: Information Visualization
https://www.readbyqxmd.com/read/28689407/direct-on-line-determination-of-laser-induced-particle-size-distribution-by-icpms
#18
Ariane Donard, Fanny Claverie, Fabien Pointurier, Céline Blitz Frayret, Barbora Svatosova, Christophe Pecheyran
The characterization of the aerosol (size, composition and concentration) generated by Laser Ablation is of great interest due to its impact on the analytical performances when coupled to Inductively Coupled Plasma Mass Spectrometry (ICPMS). The capabilities of High Resolution ICPMS as a direct tool to characterize nanoparticles produced by femtosecond Laser Ablation of pure copper are presented. An analytical protocol, similar to the 'single particle ICPMS' technique used to characterize the size distribution of nanoparticles in solution, was developed in order to observe the signals of individual particles produced by a single ablation shot...
July 8, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28679909/real-time-process-analytics-in-emergency-healthcare
#19
Vassiliki Koufi, Flora Malamateniou, Adrianna Prentza, George Vassilacopoulos
Emergency medical systems (EMS) are considered to be amongst the most crucial systems as they involve a variety of activities which are performed from the time of a call to an ambulance service till the time of patient's discharge from the emergency department of a hospital. These activities are closely interrelated so that collaboration and coordination becomes a vital issue for patients and for emergency healthcare service performance. The utilization of standard workflow technology in the context of Service Oriented Architecture can provide an appropriate technological infrastructure for defining and automating EMS processes that span organizational boundaries so that to create and empower collaboration and coordination among the participating organizations...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28674907/protein-multiplexed-immunoassay-analysis-with-r
#20
Edmond J Breen
Plasma samples from 177 control and type 2 diabetes patients collected at three Australian hospitals are screened for 14 analytes using six custom-made multiplex kits across 60 96-well plates. In total 354 samples were collected from the patients, representing one baseline and one end point sample from each patient. R methods and source code for analyzing the analyte fluorescence response obtained from these samples by Luminex Bio-Plex(®) xMap multiplexed immunoassay technology are disclosed. Techniques and R procedures for reading Bio-Plex(®) result files for statistical analysis and data visualization are also presented...
2017: Methods in Molecular Biology
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